• Journal of Pharmaceutical Investigation
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• v.35 no.1
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• pp.25-31
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• 2005

Depot system for local drug delivery using chitosan hydrogel has been developed to enhance the therapeutic efficacy and to prevent the severe side effect in whole body. Thus, we have prepared an injectable chitosan hydrogel containing liposomes to treat cancers clinically. Anionic liposomes incorporated to improve sustained release efficiency within chitosan hydrogel. The chitosan solution containing liposomes was designed to form a hydrogel complex at body temperature. The released behavior of doxorubicin from liposomes in chitosan hydrogel showed sustained-release caused by diffusion of doxorubicin from temperature responsive liposome into chitosan hydrogel. The chitosan hydorgel containing liposomes enhanced the therapeutic potency for the solid tumor in vivo system. Our results indicate that the liposomes in chitosan hydrogel represent a depot system for local drug delivery.

• Journal of Applied Reliability
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• v.11 no.2
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• pp.141-149
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• 2011

Environment Conversion Factors, which are stipulated in System Reliability Toolkit, have a lot of advantages once applied in a reliability data handbook such as NPRD-95, during the process of reliability prediction. However, the factors have a restriction in their applications because they don't deal with a few environments, e.g., Missile Launch (ML). In this study, environment factors of various components from MIL-HDBK-217F were analyzed to address this problem. Statistical computations showed that converting from Airborne Rotary Wing (ARW) to Missile Launch (ML) was the most coherent by comparing coefficient of determination. In addition, conversion factors from System Reliability Toolkit and those from the statistical calculations were evaluated in terms of their similarities.

• Journal of the Korean Operations Research and Management Science Society
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• v.21 no.2
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• pp.95-109
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• 1996

In automobile industry, the depot (distribution center) system is utilized to adjust the inventory and to supply the demands to the firm timely. In case of the small lot demands of short delivery cycle and the long distance from the parts manufacturing to the firm, the depot system is very important. In this paper, a model to minimize the sum of costs of holding, inventory and transportation, is proposed to determine the optimal quantities of production and transportation in JTT system. Finally, computational results that verify the effectiveness of the proposed model are demonstrated.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.3 no.2
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• pp.120-125
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• 2002

In this paper, we propose a new ordering model for the mixed parts transportation problem with multi-items based on the depot system. Order scale are used as decision parameters instead of order point for ordering multi-items. Finally we test the model with simple example and show computational result that verifies the effectiveness of the model.

• Journal of the Korea Society for Simulation
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• v.26 no.3
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• pp.23-34
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• 2017

This paper is to study the simulation model of depot maintenance system that analyzes logistics supportability such as component availability and cost of target equipment. A depot maintenance system could repair or maintain multiple components simultaneously. The key performance indicators of this system are component availability, repair cycle time, and maintenance cost. The simulation model is based on the engine maintenance process of army aviation depot. This study combines the NOLH(Nearly Orthogonal Latin Hypercube) experimental design method, to composes 33 scenarios, with a multiple regression analysis to find out major factors that influence on key performance indicators. This study is significant in providing a cost-effectiveness analysis on depot maintenance system that is capable of maintaining multiple components at the same time.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.20 no.12
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• pp.789-796
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• 2019

If the development of Integrated Logistics Support (ILS) for maintenance of the end step is conducted systematically and efficiently, the weapon system lifecycle can be postponed and the availability can be improved. DEFense CONdition (DEFCON) is maintained as perfect. Nevertheless, like its importance, the guide for maintaining the depot performance is applied differently for each weapon system. The errors that can result cause additional cost, etc. ILS development at depot level maintenance is different from full scale development. Therefore, this study distinguishes the management and deployment section for the development concept. An additional way to perform an efficient development of depot maintenance element when determining the depot maintenance period were presented. This study examined how the Reliability, Availability, Maintainability (RAM), Logistics Support Analysis (LSA), and ILS 11 elements intersect at the depot maintenance sources. An analytical study of concrete adoptable plans was performed. The systematic adoption of a development procedure can make it possible to calculate the adoptable development cost. In addition, it can be helpful for improving the quality level and practical use of work products.

• Proceedings of the KSR Conference
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• 2002.10a
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• pp.497-502
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• 2002

TGIS(Train General Information System) is monitoring Train status and analyzing fault happened. TGIS informed a lot of Passenger data, Driving data, Status data and Fault data to 'Depot'. For dealing them more properly, TGIS need specified data and specialized data handling method. This paper suggest Optimize data of Train Monitoring System and Apply that to Main Line Car.

• Journal of the Korean Operations Research and Management Science Society
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• v.24 no.3
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• pp.1-11
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• 1999

We consider the problem of determining the spare inventory level for a multiechelon repairable-item inventory system. Our model extends the previous results to the system which has an inventory at the central depot as well as bases. We develop an optimal algorithm to find spare inventory leveis, which minimize the total expected cost and simultaneously satisfy a specified minimum service rate. The algorithm is tested using problems of various sizes to verify the efficiency and accuracy.

• Journal of Korean Society of Industrial and Systems Engineering
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• v.20 no.43
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• pp.99-107
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• 1997

We consider a multiechelon repairable-item inventory system where several bases are supported by a central depot and the external repair facilities. Unlike METRIC- based models, there are only a finite number of repair channels at each base, central depot and the external repair facilities. It is desired to find repair capacities and spares level which together guarantee a specified service level at minimum cost. Closed queueing network theory is used to model the stochastic process. The purpose of this paper is to derive the steady-state distributions of this system.

• Proceedings of the Korean Institute of Navigation and Port Research Conference
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• 2018.11a
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• pp.152-154
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• 2018

Inland Container Depot is regarded as an important link in the multimodal transport, contributing to reduce transportation costs, reduce the time saved at the port, with the main function of clearing domestic goods, empty containers and refrigerated containers, super cargo. Inland Container Depot has just used in the South of Vietnam in recent years which are starting in the business. In this paper, i want to research on the potential of dry ports including the development and effective for economic of Vietnam.