• 디지털산업정보학회논문지
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• 제15권3호
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• pp.89-100
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• 2019

Uniform and integrated college desks and chairs have low efficiency of loading for transportation and delivery and low efficiency of storage for warehousing due to their simple uniform physical properties, thus increasing logistics costs for companies and decreasing their competitiveness. In an effort to overcome the limitations of previous studies, this study analyzed the stages of logistics for desks and chairs in college lecture rooms via the transportation route including the factory warehouses and local warehouses and via the delivery route from local warehouses by the region to the orderers including college lecture rooms. The study developed a model for the rationalization of corporate logistics by making a variable folding desk and chair capable of distance adjustment according to height to replace the uniform and integrated college desks and chairs in lecture rooms. A model was developed between the old uniform and integrated college desks and chairs and the new variable folding desks and chairs for three scenarios of cost development including product storage costs, transportation costs from the specialized factory warehouses to the local warehouses by the region, and delivery costs from the local warehouses to college lecture rooms as the orderer. For the generalization of the model, it was applied to each of the 90%, 95%, and 99% service levels.

• 전력전자학회:학술대회논문집
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• 전력전자학회 2003년도 춘계전력전자학술대회 논문집(1)
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• pp.477-480
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• 2003

Generally, 2 phase excited brushless DC motor(BLDCM) operates only in the region of constant trapezoidal back-EMF on each phase. Therefore the efficiency decreases in comparison with 3phase excited BLDCM. This paper proposes the relation between the usage ratio of voltage and the change of fewer delivery of BLDCM according to extension of conduction intervals.

• 대한수의사회지
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• 제21권3호
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• pp.164-169
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• 1985

The survey was carried out to investigate calving interval, gestation period, the interval between parturition and first breeding and the duration from delivery to conception in the total of 320 heads of Holstein cows being fed in the suburbs of Suwon. Th

• 한국진공학회:학술대회논문집
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• 한국진공학회 2013년도 제45회 하계 정기학술대회 초록집
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• pp.92.2-92.2
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• 2013

The design and chemical synthesis of multifunctional nanomaterials have been providing potential applications in biomedical fields such as molecular imaging and drug delivery. Recently, bio-derived and/or synthetic nanostructured materials capable of modulating the immune system have been also issues of interest in immunology-related nanomedicine fields. In this talk, the recent research results on the development of nanostructured materials for enhanced immunity would be presented. I will introduce the chemical strategy for the combination of nanostructured materials and bioactive compounds to improve both anti-cancer immunity and vaccine delivery efficiency.

• 대한의생명과학회지
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• 제9권2호
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• pp.67-74
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• 2003

Viral and non-viral vectors have been used in the delivery of genetic materials into animal cells and tissues, with each approach having pros and cons. Non-viral vectors have many useful merits such as easy preparation, low immunity and size tolerance of a transgene when compared to those of viral vectors. Delivery specificity may be achieved by complex formation between receptor ligands and a non-viral vector. In the present study, non-viral vector systems are investigated in an effort to find a practical delivery means for gene therapy, Receptor-ligand interaction between transferrin-receptor and transferrin was utilized for efficient gene transfer into cancer cells. A plasmid vector, pcDNA3 (LacZ) was ligated with a small duplexed oligo fragment in which a Biotin- VN$^{TM}$ phosphoramidite was placed in the middle of the oligo. The plasmid vector labeled by biotin was then conjugated with biotin-labeled transferrin via streptavidin. This trimeric conjugates were delivered to a hepatoma cell line, HepG2. The delivery efficiency of the trimeric conjugate was 2-fold higher than that of cationic liposomes used for transfection of a plasmid vector. These results demonstrate that a plasmid vector can be efficiently transferred into cells by forming a trimeric complex of plasmid vector-linker-ligand.

• 폴리머
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• 제36권2호
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• pp.149-154
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• 2012

생체적합성을 가진 키토산과 강력한 항산화제로 알려진 리포산을 합성하여 만든 양친매성 고분자를 이용하여 약물전달시스템으로서의 응용 가능성을 알아보았다. 수용액 상에서 자기조립의 성질을 가지는 양친매성 고분자는 나노입자를 형성하고 이 입자 안에 항암제로 널리 쓰이는 5-fluorouracil을 고체분산법을 이용하여 봉입하였다. 최적의 약물전달체를 얻기 위하여 키토산에 결합된 리포산의 비율을 조절하여 입자크기 및 약물봉입률을 비교하였다. DLS를 이용하여 측정한 나노입자는 약 250 nm 정도의 크기를 가졌고 그 봉입률은 10% 내외로 측정되었다. 42%의 리포산 치환율을 가지는 공중합체가 약물전달체로서 가장 우수한 성능을 보여주었다.

• KSII Transactions on Internet and Information Systems (TIIS)
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• 제5권1호
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• pp.141-156
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• 2011

In this paper we develop a link cost function for data delivery in sensor network. Usually most conventional methods determine the optimal coefficients in the cost function without considering the surrounding environment of the node such as the wireless propagation environment or the topological environment. Due to this reason, there are limitations to improve the quality of data delivery such as data delivery ratio and delay of data delivery. To solve this problem, we derive a new cost function using the concept of Partially Connected Neural Network (PCNN) which is modeled according to the input types whether inputs are correlated or uncorrelated. The correlated inputs are connected to the hidden layer of the PCNN in a coupled fashion but the uncoupled inputs are in an uncoupled fashion. We also propose the training technique for finding an optimal weight vector in the link cost function. The link cost function is trained to the direction that the packet transmission success ratio of each node maximizes. In the experimental section, we show that our method outperforms other conventional methods in terms of the quality of data delivery and the energy efficiency.

• 대한안전경영과학회지
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• 제24권3호
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• pp.29-37
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• 2022

The development of technology related to the Fourth Industrial Revolution and the growth of the online market due to pandemic are continuing the growth of the logistics market for product delivery. If it is difficult to deliver the product directly to the customer during delivery, storage and delivery using the unmanned courier box are being carried out. However, existing storage boxes are not actively used due to lack of usability even though they have the advantage of storing goods and delivering non-face-to-face. In addition, existing courier boxes are not prepared for cold chain transportation. The unmanned delivery storage device with ICT cold chain technology should be developed to prepare for the transition to non-face-to-face society, to improve logistics efficiency and meet user's requirements. Also, it is necessary to consider the measures to reduce the safety problems that may occur during the use and maintenance of the automatic system. This study conducted a model-based analysis for the development of unmanned delivery storage devices with ICT cold chain technology, and conducted a study to derive the system development specifications that meet the requirements and secure safety and apply them to the development process.

• 대한안전경영과학회지
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• 제19권3호
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• pp.129-135
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• 2017

The respective delivering vehicle loaded with the own cargo moves into the respective delivery area. At the base, the delivery points D1 and D2, for example, have the same starting point but the destination is different. The average delivering time of the delivery vehicle is mostly more than 8 hours a day. Therefore, the efficiency of delivery is generally low. In this study, the deliveries will be forwarded from a base station to a delivery point where cross docking will be applied to a single vehicle, and will be distributed from the cross docking point through cross docking. If the distribution is implemented, one vehicle will not have to be operated from the base to the cross docking point. In that case, logistics cost will be reasonably saved by the reduction of transportation cost and labor time. If one vehicle only runs from the base to the cross docking point, each vehicle will be operated in two shifts, and the vehicle operation can be efficiently implemented. This research model is based on the assumption that the 3 types of ratios between the traffic volume of the vehicles starting at the base and the vehicles waiting at the cross docking point are set to the first ratio of 30% to 70%, the second ratio of 50% to 50% and the final ratio of 70% to 30%. As a result of the study, The delivery time in the cross docking point is much higher than that in present on the condition that the cargo volume in the D2 area is more than 50%. Likewise, the delivery time is slightly higher on the condition that the cargo volume is less than 50%. Time is reduced in terms of 50% model like AS-IS model.

• Reproductive and Developmental Biology
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• 제28권1호
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• pp.71-76
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• 2004

Gene delivery is one of the keen interests in animal industry as well as research on gene functions. Some of the in vivo gene delivery techniques have been successively used in various tissues for the gene therapy and transgenesis. Despite intensive efforts, it still remains to overcome problems of limited local and regional administration and low transgene expression. To improve the efficiency of gene delivery, a new procedure was tested. We injected exogenous DNA containing LacZ into the female or male gonads and then pulsed electric field. Electroporated gonads showed positive X-gal staining in many seminiferous tubules of the porcine fetal gonads. Exogenously introduced LacZ genes were also expressed in female porcine gonad. In addition, we demonstrated efficient gene delivery in gonad of adult mouse. Furthermore, we succeed to generate genetically modified germline cells showing GFP and positive X-gal signals. The results suggest that the newly developed gene delivery is an effective way of in vivo transfection in mammals. The developed gene delivery procedure should be useful in producing transgenic animals when combined with primary cell culture and nuclear transplantation.