• Title/Summary/Keyword: Delivery Process

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Large-scale Synthesis of Uniform-sized Nanoparticles for Multifunctional Medical Applications

  • Hyeon, Taeg-Hwan
    • Proceedings of the Korean Vacuum Society Conference
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    • 2011.02a
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    • pp.1-1
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    • 2011
  • We developed a new generalized synthetic procedure, called as "heat-up process," to produce uniform-sized nanocrystals of many transition metals and oxides without a size selection process. We were able to synthesize uniform magnetite nanocrystals as much as 1 kilogram-scale from the thermolysis of Fe-oleate complex. Clever combination of different nanoscale materials will lead to the development of multifunctional nano-biomedical platforms for simultaneous targeted delivery, fast diagnosis, and efficient therapy. In this presentation, I would like to present some of our group's recent results on the designed fabrication of multifunctional nanostructured materials based on uniform-sized magnetite nanoparticles and their medical applications. Uniform ultrasmall iron oxide nanoparticles of <3 nm were synthesized by thermal decomposition of iron-oleate complex in the presence of oleyl alcohol. These ultrasmall iron oxide nanoparticles exhibited good T1 contrast effect. In in vivo T1 weighted blood pool magnetic resonance imaging (MRI), iron oxide nanoparticles showed longer circulation time than commercial gadolinium complex, enabling high resolution imaging. We used 80 nm-sized ferrimagnetic iron oxide nanocrystals for T2 MRI contrast agent for tracking transplanted pancreatic islet cells and single-cell MR imaging. We reported on the fabrication of monodisperse magnetite nanoparticles immobilized with uniform pore-sized mesoporous silica spheres for simultaneous MRI, fluorescence imaging, and drug delivery. We synthesized hollow magnetite nanocapsules and used them for both the MRI contrast agent and magnetic guided drug delivery vehicle.

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A Study on the Successful Operation for the Integration of Cyber Logistics (성공적(成功的)인 사이버 통합(統合) 물류(物流) 운영(運營)에 관(關)한 연구(硏究) -전자상거래(電子商去來)(홈쇼핑) 업체(業體)와 택배(宅配) 업체(業體)를 중심(中心)으로-)

  • Kim, Sang-In;Choi, Hong-Do;Kang, Kyung-Sik
    • Journal of the Korea Safety Management & Science
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    • v.17 no.4
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    • pp.247-258
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    • 2015
  • The purpose of this study is to let the entire logistics system be managed in cyberspace by effectively sharing the logistics information between companies involved in the process, changing conventional commerce to electronic commerce. Most of the goods traded through electronic commerce are small goods involving small business transactions. This produces many problems in shipping and delivery and the leads an inefficient logistics system. Another problems is that there is no sharing of information that process the logistics flow and no systematic management of pick-up and delivery information. As a result, rise in logistics cost, longer delivery period and poor service quality are inevitable and these results are becoming an obstacle in the widespread usage of the electronic commerce. Companies that are part of logistics center can cooperate logistics business in Cyber space and share the entire logistics information through the cyber logistics center. This turns out in effective sharing of logistics information, and thus, allows efficient management of logistics, improves logistics service, and reduces logistics cost.

Information Delivery Scheme by Using DTN in Battlefield Eenvironment (전장 환경에서 DTN을 이용한 정보전달기법)

  • Kim, Young-An
    • The Journal of Korean Institute of Communications and Information Sciences
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    • v.36 no.3B
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    • pp.260-267
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    • 2011
  • Wireless Local Area Network (WLAN) is recently become popular on the internet since we can download and transfer mass data through it. However, transferring data with distances over 100m often causes some troubles. When downloading mass data from moving vehicles such as cars, jeeps, tanks, etc., if the download process from the first AP (Access Point) is not completed then we have to re-start this process from the second AP (from 0%). Therefore, the question is how to maintain the data we have received from the first AP, and then continuously download remaining data from the next APs in a battlefield environment. In this paper, we propose an effective method for receiving mass data separately from the mobile receive nodes in a Delay Tolerant Network (DTN). We carried on an experiment and evaluation by simulation; these simulation results are provided to show the proposed information delivery scheme performance.

Pregnant Women's Labor Progress, Childbirth Outcome, and Childbirth Satisfaction according to the Presence or Absence of Labor Induction (유도분만 시행 여부에 따른 임산부의 분만진행과정, 분만결과, 분만만족도)

  • Jeong, Yun Ah;Chung, Chae Weon
    • Women's Health Nursing
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    • v.24 no.1
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    • pp.58-70
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    • 2018
  • Purpose: To provide accurate information on induced labor and find strategies to enhance women's childbirth satisfaction. Methods: Participants were pregnant women expected to have normal vaginal delivery. A total of 113 women with induced labor and 61 women with spontaneous labor were surveyed. Data were collected using a questionnaire and electronic medical records. Results: The following variables related to labor progress showed significant differences between the induced labor group and the spontaneous labor group: length of the first stage of labor in primigravidas, use of analgesic, incidence of uterine hyperstimulation, incidence of fetal distress, and medical treatment for the expectant mother. Delivery type and the incidence of postpartum complications showed significant difference between the two groups. Induced labor women's childbirth satisfaction was mainly affected by the process of labor whereas spontaneous labor women's childbirth satisfaction was affected by the outcome of childbirth. Conclusion: Medical staff should have accurate information on the risk of induced labor and the benefits of a natural delivery. Moreover, medical staff should provide necessary information and environment for women to participate in the decision-making process.

A study on MRP/JIT system for vendor management

  • Lee, Soon-Yo;Yang, Seun-Mo
    • Korean Management Science Review
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    • v.5 no.2
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    • pp.57-70
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    • 1988
  • This paper examines both MRP and JIT for reducing WIP(Work In Process). The MRP/JIT system is suitable for multi-model, small-production manufacturing comparies in Korea because of the short delivery distance and low risk of accident during delivery. The objective of this paper is to manage vendors effectively by informing supply points and quantity of parts of vendors with MRP and JIT.

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Multivesicular DepoFoam particles for oral delivery of recombinant human epidermal growth factor

  • Li, Hong;An, Jun-Hee;Park, Jeong-Sook;Han, Kun
    • Proceedings of the PSK Conference
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    • 2003.04a
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    • pp.299.1-299.1
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    • 2003
  • Multivesicular DepoFoam technology is best suited for the encapsulation and sustained release of water-soluble drugs. The purpose of the present study was to prepare multivesicular DepoFoam particles and investigated possibility of oral delivery of a peptide, human epidermal growth factor (rhEGF). The multivesicular DepoFoam particles containing rhEGF was prepared by a two step water-in-oil-in-water double emulsification process. (omitted)

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Microbiological Assessment of Home-Delivered Meals for Children from Low-income Families during Production and Delivery (결식아동을 위한 가정배달 도시락의 생산과 배달과정 중 미생물적 평가)

  • Moon, Jeong-A;Yoo, Chang-Hee;Lee, Kyung-Eun
    • Journal of the Korean Dietetic Association
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    • v.19 no.3
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    • pp.236-252
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    • 2013
  • The purpose of this study was to assess the microbiological quality of home-delivered meals during production and delivery for children from low-income families. Production flows from a facility in Seoul that provides home-delivered meals were analyzed and the time-temperature of the food was measured. Microbiological assessment was performed for the production environment, personal hygiene, and food samples at each production and delivery step based on the process approach. It took 2 hours or longer from completion of production to meal delivery. An aerobic colony count (ACC) and coliform were not detected at knives, cutting boards, and dish towels. However, ACC (at pre-preparation, preparation, and packing areas) and coliform (at the preparation area) were detected on the hands and gloves of employees. Air-borne bacterial counts varied according to day and preparation area (ND~6 CFU/plate/15 min). Food temperatures, on the completion of production and meal delivery, fell into temperature danger zones. ACC and coliform counts of raw ingredients did not decrease after pre-preparation (washing and sanitizing) for menus involving food preparation with no cook step. ACC decreased after cooking step for menus of food preparation with cook step, but the ACC of the stir-fried and seasoned dried filefish fillet on the completion of cooking was too numerous to count due to improper heating. The ACC of seasoned young Chinese cabbages (a menu with complex food preparation) increased during delivery (from 2.5 log CFU/ml to 5.0 log CFU/ml). This qualitative assessment of foodborne pathogens revealed that B. cereus was detected in vegetable and meat product menus. These results suggest time-temperature control is necessary during production and delivery and management guidelines during production of home-delivered meals are provided for safe production.

A Study on Development of A GPS navigation system based on RFID which contains location information (위치정보가 기록된 RFID를 이용한 택배차량용 내비게이션 시스템 개발에 관한 연구)

  • Shim, Jin-Bum;Han, Yeong-Geun
    • Journal of the Korea Safety Management & Science
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    • v.12 no.1
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    • pp.113-118
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    • 2010
  • "Domestic delivery service" is defined the service to deliver goods or packages from point of senders to point of receiver. With the characteristics of door to door, it is must a service provider should know the exact location of destination assuring best utilization of moving path. Generally, location information consist of postal code and address only, which result in difficulties to identify the precise location of destination. It is relatively less correlated between the information that address refers and practical location in Korea address system. For example, the next door to house number 100 is not always house number 101. Therefore, a delivery man additionally uses a paper map or a GPS navigation which carry extra job to input every code of location to the device in order to know precise location. It is also very inconvenient that every delivery man identify the location that address information refers and make a personal decision of the optimum moving path dropping each destination without calculating provisioning process of whole delivery path. As explained above, it is inefficient to find information delivery service required and to generate the optimum path. In results, these difficulties bring in delay of service and increase of cost. In this point, the contents of the thesis suggest a GPS navigation system easy to obtain accuracy of delivery information which enables to automate optimum moving path based on RFID which contains location information.

Feasibility on Statistical Process Control Analysis of Delivery Quality Assurance in Helical Tomotherapy (토모테라피에서 선량품질보증 분석을 위한 통계적공정관리의 타당성)

  • Kyung Hwan, Chang
    • Journal of radiological science and technology
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    • v.45 no.6
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    • pp.491-502
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    • 2022
  • The purpose of this study was to retrospectively investigate the upper and lower control limits of treatment planning parameters using EBT film based delivery quality assurance (DQA) results and to analyze the results of statistical process control (SPC) in helical tomotherapy (HT). A total of 152 patients who passed or failed DQA results were retrospectively included in this study. Prostate (n = 66), rectal (n = 51), and large-field cancer patients, including lymph nodes (n = 35), were randomly selected. The absolute point dose difference (DD) and global gamma passing rate (GPR) were analyzed for all patients. Control charts were used to evaluate the upper and lower control limits (UCL and LCL) for all the assessed treatment planning parameters. Treatment planning parameters such as gantry period, leaf open time (LOT), pitch, field width, actual and planning modulation factor, treatment time, couch speed, and couch travel were analyzed to provide the optimal range using the DQA results. The classification and regression tree (CART) was used to predict the relative importance of variables in the DQA results from various treatment planning parameters. We confirmed that the proportion of patients with an LOT below 100 ms in the failure group was relatively higher than that in the passing group. SPC can detect QA failure prior to over dosimetric QA tolerance levels. The acceptable tolerance range of each planning parameter may assist in the prediction of DQA failures using the SPC tool in the future.

Analysis of Guidelines and Ordering Cases for BIM Deliverable Delivery System Development in Road Sector (도로분야 BIM 성과품 납품체계 개발을 위한 국내외 지침 및 발주사례 분석)

  • Seo, Myoung-Bae;Kim, Jin-Uk;Choi, Won-Sik;Ju, Ki-Beom
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.14 no.11
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    • pp.5897-5905
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    • 2013
  • In spite of advantage by using BIM as quantity take-off, schedule control and clash check, absence of guidelines is a barrier to applying BIM to road domain. In this research, domestic and overseas cases of BIM guideline are analyzed in order to develop the road BIM deliverable submission system. The analysis is classified 5 topics which are BIM submit product list, submit files format, availability of existing 2D based products, BIM authoring tools and submit process. As a result, It needs a lot of effort to standardize BIM delivery system for road domain because BIM submit product list and BIM authoring tools are changable depending on BIM use cases. However, submit files format and submit process are common part to suggest guidelines of road BIM delivery system. It requires to combine BIM and 2D products for road BIM delivery system because delivery products are not exactly alternative 2D based delivery products for the present. The authors expect this research to use as basic data for development of the BIM deliverable submission system in road domain.