• Journal of Pharmaceutical Investigation
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• v.29 no.3
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• pp.217-225
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• 1999

These studies were designed to determine the effect of hydroalcoholic gel system (lower alkanol concentration: 40-60%) compared to general hydrogel system (lower alkanol concentration: 10-35%) on transdermal delivery of piroxicam and its anti-inflammatory activity. Piroxicam was incorporated into a hydroalcoholic gel and a hydrogel containing polymers, solvents, and cosolvents. The pH of gel was about 6.3-7.3 and the solvent mixtures were composed of water and various concentrations of ethanol (35, 40, 50, and 60%). For the in vitro study, the skin permeation of piroxicam from the gel formulations was investigated using Franz modified diffusion cells fitted with hairless mouse skin. For the in vivo study, the anti-inflammatory activity of hydroalcoholic gel was compared to other commercial products (piroxicam hydrogel and ketoprofen hydrogel) in rat and human. The anti-inflammatory activity was determined using carrageenan induced foot edema model in rat. For the clinical study, it was evaluated from determining efficacy and acceptability with 98 patients suffering from musculoskeletal pain. A novel piroxicam hydroalcoholic gel was successfully formulated in the range of 40-50% of ethanol as solvent, more than 10% of propylene glycol, 5% of $Transcutol^{\circledR}$ and 1 % of benzyl alcohol. The skin permeation of piroxicam using hydroalcoholic gel system was greater than that of general hydrogel system $(flux\;:\;139.1-148.2\;{\mu}g/cm^2/hr\;vs.43.0-84.5 {\mu}g/cm^2/hr)$ in vitro. In carrageenan-induced edema model, the anti-inflammatory activity of hydroalcoholic gel was better than that of piroxicam hydrogel for edema inhibition (75.1 % vs. 62.9%, p

• Journal of Korean Society on Water Environment
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• v.23 no.4
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• pp.518-526
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• 2007

There have been serious soil erosion and water pollution problems caused by highland agriculture practices at Doam-dam watershed. Especially agricultural activities, chemical and organic fertilizer and pesticide applications, soil reconditioning to maintain soil fertility are known as primary causes of soil erosion and water qaulity degradation in the receiving water bodies. Among these, soil reconditioning can accelerate soil erosion rates. To develop soil erosion prevention practices, it is necessary to estimate the soil erosion from the watershed. Thus, the Universal Soil Loss Equation (USLE) model has been developed and utilized to assess soil erosion. However, the USLE model cannot be used at watershed scale because it does not consider sediment delivery ratio (SDR) for watershed application. For this reason, the Sediment Assessment Tool for Effective Erosion Control (SA TEEC) was developed to assess the sediment yield at any point in the watershed. The USLE-based SA TEEC system can estimate the SDR using area-based SDR and slope-based SDR module. In this study, the SATEEC system was used to estimate soil erosion and sediment yield at the Doam-dam watershed using the soil properties from reconditioned agricultural fields. Based on the soil sampling and analysis, the US LE K factor was calculated and used in the SA TEEC system to analyze the possible errors of previous USLE application studies using soil properties from the digital soil map, and compared with that using soil properties obtained in this study. The estimated soil erosion at the Doam-dam watershed without using soil properties obtained in the soil sampling and analysis is 1,791,400 ton/year (123 ton/ha/year), while the soil erosion amount is 2,429,900 ton/year (166.8 ton/ha/year) with the use of soil properties from the soil sampling and analysis. There is 35 % increase in estimated soil erosion and sediment yield with the use of soil properties from soil reconditioned agricultural fields. Since significant amount of soil erosion are known to be occurring from the agricultural fields, the soil erosion and sediment yield from only agricultural fields was assessed. The soil erosion rate is 45.9 ton/ha/year without considering soil properties from soil reconditioned agricultural fields, while 105.3 ton/ha/year after considering soil properties obtained in this study, increased in 129%. This study shows that it is very important to use correct soil properties to assess soil erosion and sediment yield simulation. It is recommended that further studies are needed to develop environment friendly soil reconditioning method should be developed and implemented to decrease the speed of soil erosion rates and water quality degradation.

• Journal of Internet Computing and Services
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• v.4 no.5
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• pp.11-19
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• 2003

Since B2C(Business to Customer) from which e-commerce had originated was replaced by B2B, e-Business has shown fast growth so fa., Recently, e-Procurement by l:n concept is on the development as self-purchase system associated with their own ERP In many conglomerates in the Korean market. However, in order to vitalize e-Biz in the plant industry, we need to set up e-marketplaces where many sellers and buyers can meet each other at the same time, which has become the essential part for success as an expanded business model. In this paper, we expect that the foundation for e-transformation in the plant industry is set up by developing Purchase Process System and related modules as the prerequisite for e-Biz in the plant industry, and this report will provide an exemplary model for e-commerce. The Purchase Process System consists of 1) e-Purchasing Module that manages bidding and contract information based on quotation inquiry, 2) e-Expediting Module that manages information to guarantee the on-time delivery, 3) e-Certification Module that controls user authentification, 4) e-Basic Module that manages the bulletin boards, Q&A, etc.

• The Journal of Society for e-Business Studies
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• v.24 no.3
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• pp.111-128
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• 2019

In the current procurement system in Korean military, the army, navy and air force have their own distributors, military branches and warehouses. However, especially, it has been hard to have the economy of scale because most of suppliers have shipped their order from the suppliers to each of Korean military directly. Koran military considers the transportation cost as one of the management cost factors among various kinds of cost. Furthermore they have contracted with the suppliers in annual and collectively on the transportation. Hence they have been in trouble with getting efficiency of Defense budget execution because it is hard to make a decision of Defense budget with real transportation cost. Moreover Korean army, navy and air force have their own supply chain separately, so they can not cooperate flexible and quickly when they need. Therefore, in this research, we provide a benchmarking of DTCI (Defense Transportation Coordination Initiative) which has been proved that it has improved the procurement system in US implementing the integrated transportation system with 3PL and military. In addition we propose advanced integrated shipping model using Hub & Spoke system for Korean military. In order to prove its effect, we simulate our model based on the real data of the suppliers' delivery to compare with the current system when it comes to how much we can save the cost. Our research can provide evidence that the integrated procurement system in Korean military will improve Korean military procurement system.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.19 no.12
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• pp.287-293
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• 2018

The Korean peninsula has been known as an area that is free of volcanic disasters. However, recent observations and research results of volcanoes in Far East Asia, including Baedu Mountain and Japanese volcanoes, show that the Korean peninsula is no longer a safe area from volcanic disasters. Since 2012, the Korean government has been developing an IT-based construction technology, VDRS (Volcanic Disaster Response System), for effective volcanic disaster response system. The main users of VDRS are public officers in central or local governments. However, most of them have little experience and knowledge about volcanic disasters. Therefore, it is essential to develop education contents and implement training on volcanic disaster response for effective response in a real disaster situation. In this paper, we deal with the development of a mobile application based on virtual reality (VR) for realistic volcanic disaster response training. The objectives of training are the delivery of knowledge and experience for volcanic disasters. First, VR contents were generated based on spatial information. A 3D model was constructed based on a Digital Elevation Model (DEM), and visualization models for meterological effects and various volcanic disaster diffusion effects were implemented for the VR contents. Second, the mobile application for the volcanic disaster response training was implemented. A 12-step story board is proposed for volcanic disaster experience. The application was developed with the Unity3D engine based on the proposed story board to deliver knowledge of various volcanic disasters (volcanic ash, pyroclastic flows, volcanic mudflow etc.). The results of this paper will be used for volcanic disaster response and prevention training and for more realistic training linked with augmented reality technology in the future.

• Journal of Navigation and Port Research
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• v.44 no.6
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• pp.524-533
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• 2020

The free-trade-zone system has been implemented in industrial-complex-type free-trade zones with a focus on the manufacturing industry since 1970, and was intended to attract foreign investment and increase trade by providing benefits such as tax reduction and deregulation to tenant companies. However, foreign investment in these industrial-complex-type free trade zones has decreased significantly. On the other hand, port-type free-trade zones have great potential to attract foreign investment for development due to the increase in port traffic. The developmental trends in the free-trade-zone system have been studied primarily in the manufacturing industry, and those studies must be extended. In this paper, the role and operation of free-trade zones are examined and problems highlighted. We analyzed a business model specialized in port-type free-trade zones to identify problems, propose measures to improve the system for re-exporting domestic goods to the customs area for storage, and upgrade overall operations. The effects of our measures were analyzed by simple simulation. These proposed improvements in the operation of port-type free-trade zones will help attract foreign companies to these international logistics hubs and global delivery centers.

• 한국노년학
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• v.37 no.3
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• pp.567-582
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• 2017

The purpose of this study is to investigate the path model consisted of action planning, physical activity, and depression in order to obtain an enhanced understanding of their relationship and to support the aged with depression in community. In order to achieve this, precedent study was reviewed and the program with physical activity and action planning was executed. the data of a investigation of action planning, physical activity, and depression of the aged participated in the program which was consisted of physical activity with Action Planning was used and 116 cases were analyzed. The data analysis was done by descriptive statistics, correlation analysis, and path analysis. The results were as follows. First, the path model was accepted. Second, the direct path of action planning to physical activity was significant. Third, the direct path of both action planning and physical activity to depression were significant. Fourth, the effect size of action planning to depression was more than that of physical activity. Fifth, the indirect path of action planning to depression through physical activity was significant. On the basis of these results, this suggests a need to add action planning on national physical activity plan, establish the delivery system for physical activity program with action planning in mental health center in community, and applicate narrative approach skills for qualitative improvement of action planning.

• Journal of KIBIM
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• v.10 no.1
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• pp.9-22
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• 2020

Recently, BIM has been extended to infrastructures such as roads and bridges, and the demand for BIM standard development for ports is increasing internationally. Due to the low level of utilization of classification system and drawing standards compared to other infrastructures, and the closed nature of national security facilities, ports have insufficient level of connection and sharing environment among external systems or users. In addition, since the standardization of data for port facilities is not made, it is still necessary to establish an independent DB for each system and to ensure interoperability of data between these systems since it does not have a shared environment among similar data. Therefore, the purpose of this study is to develop and verify IFC, the international standard for BIM, in order to cope with the BIM environment and to be commonly used in the design, construction, and maintenance of port facilities. To this end, we build a standard schema with port-specific Express Notation according to buildingSMART International's standard development methodology. First, domestic and international reference model standards were analyzed to derive components such as space and facilities of port facilities. Based on this, the components of the port facility were derived through the codification, categorization, and normalization process developed by the research team. This was extended based on the port BIM object classification system developed by the research team. Normalization results were verified by designers and associations. Then, IFC schema construction was based on Express-G data modeling based on IFC 4 * 2 Candidate, which is a bridge candidate standard based on IFC4 (ISO16739), and IFC 4 * 3 Draft, which is developed by buildingSMART International. The final schema was validated using the commercialized validation tool. In addition, in order to verify the structural verification of the port IFC schema, the transformation process was verified by converting the caisson model into a Part21 file. In the future, this result will not only be used as a delivery standard for port BIM products, but will also be applied as a linkage standard between systems and a common data format for port BIM platforms when BIM is used in the maintenance phase. In particular, it is expected to be used as a core standard for data exchange in the port maintenance stage.

• The Journal of the Convergence on Culture Technology
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• v.8 no.4
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• pp.303-311
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• 2022

Recently the telemedicine platform firms which have been temporarily permitted since COVID-19 outbreak have increasingly provided online prescription drugs delivery, causing concerns among incumbent providers of medicine, some of whom began to take aggressive actions again them. In this study, using game theoretic market entry - deterrence model, we show that although the incumbent medicine provider can effectively deter entry by the telemedicine platform firms by its preemptive action, accommodation could be a optimal action when telemedicine platform firms already have penetrated the market with their being permitted to do business due to the COVID-19. However, for the incumbent to cooperate for the successful change in the retail market for medicines, policies like placing a ceiling on the maximum number of taking prescriptions by the pharmacists a day in the telemedince platform network, providing favorable exposure of community pharmacists on the telemedicine platform user interface, and allowing community pharmacies to participate as shareholders of the telemedicine platform firms in its initial public opening of capital, are suggested.

• Asia pacific journal of information systems
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• v.18 no.4
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• pp.27-55
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• 2008

Due to the increasing and intensifying competition in the Internet shopping market, it has been recognized as very important to develop an effective policy and strategy for acquiring loyal customers. For this reason, web site designers need to know if a new Internet shopping mall(ISM) will be accepted. Researchers have been working on identifying factors for explaining and predicting user acceptance of an ISM. Some studies, however, revealed inconsistent findings on the antecedents of user acceptance of a website. Lack of consideration for individual differences in user ability is believed to be one of the key reasons for the mixed findings. The elaboration likelihood model (ELM) and several studies have suggested that individual differences in ability plays an moderating role on the relationship between the antecedents and user acceptance. Despite the critical role of user ability, little research has examined the role of user ability in the Internet shopping mall context. The purpose of this study is to develop a user acceptance model that consider the moderating role of user ability in the context of Internet shopping. This study was initiated to see the ability of the technology acceptance model(TAM) to explain the acceptance of a specific ISM. According to TAM. which is one of the most influential models for explaining user acceptance of IT, an intention to use IT is determined by usefulness and ease of use. Given that interaction between user and website takes place through web interface, the decisions to accept and continue using an ISM depend on these beliefs. However, TAM neglects to consider the fact that many users would not stick to an ISM until they trust it although they may think it useful and easy to use. The importance of trust for user acceptance of ISM has been raised by the relational views. The relational view emphasizes the trust-building process between the user and ISM, and user's trust on the website is a major determinant of user acceptance. The proposed model extends and integrates the TAM and relational views on user acceptance of ISM by incorporating usefulness, ease of use, and trust. User acceptance is defined as a user's intention to reuse a specific ISM. And user ability is introduced into the model as moderating variable. Here, the user ability is defined as a degree of experiences, knowledge and skills regarding Internet shopping sites. The research model proposes that the ease of use, usefulness and trust of ISM are key determinants of user acceptance. In addition, this paper hypothesizes that the effects of the antecedents(i.e., ease of use, usefulness, and trust) on user acceptance may differ among users. In particular, this paper proposes a moderating effect of a user's ability on the relationship between antecedents with user's intention to reuse. The research model with eleven hypotheses was derived and tested through a survey that involved 470 university students. For each research variable, this paper used measurement items recognized for reliability and widely used in previous research. We slightly modified some items proper to the research context. The reliability and validity of the research variables were tested using the Crobnach's alpha and internal consistency reliability (ICR) values, standard factor loadings of the confirmative factor analysis, and average variance extracted (AVE) values. A LISREL method was used to test the suitability of the research model and its relating six hypotheses. Key findings of the results are summarized in the following. First, TAM's two constructs, ease of use and usefulness directly affect user acceptance. In addition, ease of use indirectly influences user acceptance by affecting trust. This implies that users tend to trust a shopping site and visit repeatedly when they perceive a specific ISM easy to use. Accordingly, designing a shopping site that allows users to navigate with heuristic and minimal clicks for finding information and products within the site is important for improving the site's trust and acceptance. Usefulness, however, was not found to influence trust. Second, among the three belief constructs(ease of use, usefulness, and trust), trust was empirically supported as the most important determinants of user acceptance. This implies that users require trustworthiness from an Internet shopping site to be repeat visitors of an ISM. Providing a sense of safety and eliminating the anxiety of online shoppers in relation to privacy, security, delivery, and product returns are critically important conditions for acquiring repeat visitors. Hence, in addition to usefulness and ease of use as in TAM, trust should be a fundamental determinants of user acceptance in the context of internet shopping. Third, the user's ability on using an Internet shopping site played a moderating role. For users with low ability, ease of use was found to be a more important factors in deciding to reuse the shopping mall, whereas usefulness and trust had more effects on users with high ability. Applying the EML theory to these findings, we can suggest that experienced and knowledgeable ISM users tend to elaborate on such usefulness aspects as efficient and effective shopping performance and trust factors as ability, benevolence, integrity, and predictability of a shopping site before they become repeat visitors of the site. In contrast, novice users tend to rely on the low elaborating features, such as the perceived ease of use. The existence of moderating effects suggests the fact that different individuals evaluate an ISM from different perspectives. The expert users are more interested in the outcome of the visit(usefulness) and trustworthiness(trust) than those novice visitors. The latter evaluate the ISM in a more superficial manner focusing on the novelty of the site and on other instrumental beliefs(ease of use). This is consistent with the insights proposed by the Heuristic-Systematic model. According to the Heuristic-Systematic model. a users act on the principle of minimum effort. Thus, the user considers an ISM heuristically, focusing on those aspects that are easy to process and evaluate(ease of use). When the user has sufficient experience and skills, the user will change to systematic processing, where they will evaluate more complex aspects of the site(its usefulness and trustworthiness). This implies that an ISM has to provide a minimum level of ease of use to make it possible for a user to evaluate its usefulness and trustworthiness. Ease of use is a necessary but not sufficient condition for the acceptance and use of an ISM. Overall, the empirical results generally support the proposed model and identify the moderating effect of the effects of user ability. More detailed interpretations and implications of the findings are discussed. The limitations of this study are also discussed to provide directions for future research.