• 제목/요약/키워드: Deleterious effects

검색결과 242건 처리시간 0.027초

만성폐쇄성 폐질환을 동반한 불안정성 협심증환자에서 off-pump 관상동맥우회술 (Off-pump CABG for Unstable Angina Complicated With COPD)

  • 곽기오
    • Journal of Chest Surgery
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    • 제33권2호
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    • pp.186-189
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    • 2000
  • In an attermpt to aviod the deleterious effects of cardiopulmonary by pass such as pulmonary complication neurologic complication and renal failure off-pump CABG has been rediscovered and developed. We experienced off-pump CABG in 2 cases with unstable angina complicated with COPD and report herein the cases with review of literature.

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Hepatoprotective Effect and Antioxidant Role of Caesalpinia bonducella on Paracetamol-induced Hepatic Damage in Rats

  • Gupta, Malaya;Mazumder, Upal Kanti;Kumar, Ramanathan Sambath
    • Natural Product Sciences
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    • 제9권3호
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    • pp.186-191
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    • 2003
  • The hepatoprotective effect of methanol extract of leaves of Caesalpinia bonducella was studied by means of paracetamol induced liver damage in rats. The degree of protection was measured by using biochemical parameters such as serum transaminase (SGPT and SGOT), alkaline phosphatase (ALP), bilirubin, and total protein. Further, the effects of the extract on lipid peroxidation (LPO), glutathione (GSH), superoxide dismutase (SOD), and catalase (CAT) were estimated. The methanol extract of C. bonducella (MECB) (50,100 and 200 mg/kg) produced significant (P<0.01) hepatoprotective effect by decreasing the activity of serum enzymes, bilirubin, and lipid peroxidation, while it significantly increased increased the levels of GSH, SOD, CAT, and protein in a dose dependent manner. The effects of MECB were comparable to that of standard drug Silymarin. However, at a lower dose (25 mg/kg) it could not restore the deleterious effect produced by paracetamol. The results indicate that Caesalpinia bonducella had antioxidant and hepatoprotective effects.

보조 인듀서가 터보펌프의 흡입성능에 미치는 영향 (Effect of a Booster Inducer on the Suction Performance of Turbopumps)

  • 최창호;홍순삼;김진한
    • 한국유체기계학회 논문집
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    • 제8권3호
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    • pp.42-47
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    • 2005
  • Effects of a booster inducer on the suction performance of turbopumps are investigated in this paper. To see the effect of the booster inducer, suction performance tests are conducted with and without the booster inducer for three turbopumps. It is shown that the booster inducer can enhance the suction performance of turbopumps when the tip clearance of the main inducers are relatively large. Numerical analysis are also carried out to see the effects of the booster inducer on the performance of the main inducer. The booster inducer is shown to increase the static pressure at the inlet of the main inducer and prevent growing of inlet back flows which are believed to have deleterious effects on the suction performance of the inducer.

보조 인듀서가 터보펌프의 흡입성능에 미치는 영향 (Effect of a booster inducer on the suction performance of turbopumps)

  • 최창호;홍순삼;김진한
    • 유체기계공업학회:학술대회논문집
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    • 유체기계공업학회 2004년도 유체기계 연구개발 발표회 논문집
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    • pp.552-557
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    • 2004
  • Effects of a booster inducer on the suction performance of turbopumps are investigated in this paper. To see the effect of the booster inducer, suction performance tests are conducted with and without the booster inducer for three turbopumps. It is shown that the booster inducer can enhance the suction performance of turbopumps when the tip clearance of the main inducers are relatively large. Numerical analysis are also carried out to see the effects of the booster inducer on the performance of the main inducer. The booster inducer is shown to increase the static pressure at the inlet of the main inducer and prevent growing of inlet back flows which are believed to have deleterious effects on the suction performance of the inducer.

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Biocide sodium hypochlorite decreases pigment production and induces oxidative damage in the harmful dinoflagellate Cochlodinium polykrikoides

  • Ebenezer, Vinitha;Ki, Jang-Seu
    • ALGAE
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    • 제29권4호
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    • pp.311-319
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    • 2014
  • The biocide sodium hypochlorite (NaOCl) is widely used for controlling algal growth, and this application can be extended to marine environments as well. This study evaluates the biocidal efficiency and cellular toxicity of NaOCl on the harmful dinoflagellate Cochlodinium polykrikoides, with emphasis on pigment production and antioxidant enzyme activity. The test organism showed dose-dependent decrease in growth rate on exposure to NaOCl, and the 72 h $EC_{50}$ was measured to be $0.584mg\;L^{-1}$. NaOCl significantly decreased pigment levels and chlorophyll autofluorescence intensity, indicating possible detrimental effects on the photosystem of C. polykrikoides. Moreover, it significantly increased the activities of antioxidant enzymes, suggesting the production of reactive oxygen species in the cells. These data indicate that NaOCl exerted deleterious effects on the photosynthetic machinery and induced oxidative damage in the dinoflagellate and this biocide could be effectively used for the control of algal blooms.

노인이 경험하는 긴장상태에 대한 사회적 지원의 완충효과 -노인의 생활만족도를 중심으로- (A Study on the Buffer Effects of Social Support on the Strain of the Aged)

  • 이신숙
    • 대한가정학회지
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    • 제35권4호
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    • pp.199-210
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    • 1997
  • The purpose of this study was to examine whether social support buffers the deleterious effects of strain on life satisfaction of the aged and to provide information for finding out ways of increasing their life satisfaction. The subjects of this study were 252 aged persons living in Kwangju and Joun-nam. The statistics used for data analysis were frequency percentage mean standard deviation reliablity Pearson's correlation multiple regression analysis through the SAS package program. 1) The support score from family was higher than the support from friends and the total point of life satisfaction of the aged was 28.4 which was above the median 24. 2) Social support especially the support from family buffer the negative effect of strain on life satisfaction of the aged. The result indicates that the family remains a supportive system for the aged parents Therefore A program in necessary for aged parents to promote the emotional solidarity between the aged parents and their children.

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사료 중의 곰팡이와 곰팡이 독소에 대한 문제점과 가능한 대책 (Problems and Possible Solutions about Feed Fungi and Mycotoxins)

  • 남기홍
    • 한국가금학회지
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    • 제21권2호
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    • pp.113-117
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    • 1994
  • Of the 200, 000 known species of molds, only 50 or 60 are known to be harmful to humans or livestock. Certain fungi that grow on grains and grasses can produce chemical substances called mycotoxins that adversely affect performance in poultry. There are several methods of preserving feed ingredients. The list includes: drying, antioxidants, mold inhibitors, organic acids, phosphates, cooking or toasting, fat extraction, blending and fermenting. Mold inhibitors are manufactured to inhibit mold growth and prevent the production of toxic substances. They are fungistats and not fungicides, that is, they only stop the growth of molds. Practical and cost-effective methods to detoxify mycotoxin containing feedstuffs are in great demand. 0.5% hydrated sodium calcium aluminosilicate added to the diet protected chicks from the deleterious effects of aflatoxin-contaminated feed. The dietary addition of antioxidants and methionine also significantly diminished the negative effects on body weight in chicks toxicated with 3.0 ppm aflatoxin B1.

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Ultrasensitive metal-oxide gas sensors obtained using colloidal templates

  • Kim, Il-Doo;Rothschild Avner;Hyodo Takeo;Tuller Harry L..
    • 한국고분자학회:학술대회논문집
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    • 한국고분자학회 2006년도 IUPAC International Symposium on Advanced Polymers for Emerging Technologies
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    • pp.247-247
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    • 2006
  • Chemical and physical synthesis routes were combined to prepare macroporous thin films of semiconducting metal-oxides such as $CaCu_{3}Ti_{4}O_{12}\;and\;TiO_{2}$ by sputtering onto (PMMA) microsphere templated substrates. Subsequently, the colloidal templates were removed by thermal decomposition. The remaining inorganic films comprised a monolayer of hollow hemispheres with diameter commensurate with that of the microspheres. This unique morphology increases the surface area and reduces the interfacial area between film and substrate. Consequently, the surface activity is markedly enhanced while deleterious interfacial effects between film and substrate are significantly reduced. Both effects are highly advantageous for gas sensing applications.

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Toxicity and Biomedical Imaging of Fluorescence-Conjugated Nanoparticles in Hematopoietic Progenitor Cells

  • Min, Gye-Sik;Kim, Dong-Ku
    • Reproductive and Developmental Biology
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    • 제35권4호
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    • pp.503-510
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    • 2011
  • Cellular uptake of nanoparticles for stem cell labeling and tracking is a critical technique for biomedical therapeutic applications. However, current techniques suffer from low intracellular labeling efficiency and cytotoxic effects, which has led to great interest in the development of a new labeling strategy. Using silica-coated nanoparticles conjugated with rhodamine B isothiocyanate (RITC) (SR), we tested the cellular uptake efficiency, biocompatibility, proliferation or differentiation ability with murine bone marrow derived hematopoietic stem/progenitor cells. The bone marrow hematopoietic cells showed efficient uptake with SR with dose or time dependent manner and also provided a higher uptake on hematopoietic stem/progenitor cells. Biocompatibility tests revealed that the SR had no deleterious effects on cell cytotoxicity, proliferation, or multi-differentiation capacities in vitro and in vivo. SR nanoparticles are advantageous over traditional labeling techniques as they possess a high level of cellular internalization without limiting the biofunctionality of the cells. Therefore, SR provides a useful alternative for gene or drug delivery into hematopoietic stem/progenitor cells for basic research and clinical applications.

빈곤층 편모의 스트레스와 심리적 적응: 사회적 지원의 완충효과를 중심으로 (Stress and Psychological Adjustment of Poor Single Mothers: Buffer Effects of Social Support)

  • 김영희
    • 한국생활과학회지
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    • 제7권2호
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    • pp.11-22
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    • 1998
  • Social support may be a crucial aspect in single mothers' adjustment from the loss of spouse. Using a survey data collected from 285 widowed or divorced mothers, this study investigated whether social support buffers the deleterious effects of stress on psychological adjustment among poor single mothers. Results revealed that social support is not provided for at a desirable level. After controlling the single mothers' characteristics, stress in daily life, emotional support, job status and child relationship were associated with depression of them. It was also founded that emotional support buffer the negative effect of stress on depression of single mothers. Therefore, the support programs focused on emotional support are necessary for single mothers to enhance their mental health.

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