• Title/Summary/Keyword: Delayed Growth

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A Study On The Delayed S Shaped Software Reliability Growth Model (지연 S자형 소프트웨어 신뢰도 성장모델에 관한 연구)

  • 문외식
    • Journal of the Korea Society of Computer and Information
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    • v.1 no.1
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    • pp.195-210
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    • 1996
  • For predicting the parameters and estimating the goodness of fit reliability growth model based on NHPP(Non Homogeneous Poission Process) among various reliability growth models, a Delayed S Shaped SRGM Tool is designed and Implemented. The Implemented tool is applied to real software error data, and the result Is compared and annalized.

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Growth of Human Colon Cancer Cells in Nude Mice is Delayed by Ketogenic Diet With or Without Omega-3 Fatty Acids and Medium-chain Triglycerides

  • Hao, Guang-Wei;Chen, Yu-Sheng;He, De-Ming;Wang, Hai-Yu;Wu, Guo-Hao;Zhang, Bo
    • Asian Pacific Journal of Cancer Prevention
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    • v.16 no.5
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    • pp.2061-2068
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    • 2015
  • Background: Tumors are largely unable to metabolize ketone bodies for energy due to various deficiencies in one or both of the key mitochondrial enzymes, which may provide a rationale for therapeutic strategies that inhibit tumor growth by administration of a ketogenic diet with average protein but low in carbohydrates and high in fat. Materials and Methods: Thirty-six male BALB/C nude mice were injected subcutaneously with tumor cells of the colon cancer cell line HCT116. The animals were then randomly split into three feeding groups and fed either a ketogenic diet rich in omega-3 fatty acids and MCT (MKD group; n=12) or lard only (LKD group; n=12) or a standard diet (SD group; n=12) ad libitum. Experiments were ended upon attainment of the target tumor volume of $600mm^3$ to $700mm^3$. The three diets were compared for tumor growth and survival time (interval between tumor cell injection and attainment of target tumor volume). Results: The tumor growth in the MKD and LKD groups was significantly delayed compared to that in the SD group. Conclusions: Application of an unrestricted ketogenic diet delayed tumor growth in a mouse xenograft model. Further studies are needed to address the mechanism of this diet intervention and the impact on other tumor-relevant parameters such as invasion and metastasis.

A Stochastic Analysis for Crack Growth Retardation Behavior and Prediction of Retardation Cycle Under Single Overload (단일과대하중하에서 피로균열진전지연거동 및 지연수명의 확률론적 해석)

  • Shim, Dong-Suk;Kim, Jung-Kyu
    • Transactions of the Korean Society of Mechanical Engineers A
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    • v.23 no.7 s.166
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    • pp.1164-1172
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    • 1999
  • In this study, to investigate the fatigue crack retardation behavior and the variability of retardation cycles, fatigue crack growth tests were conducted on 7075-T6 aluminum alloy under single tensile overload. A retardation coefficient, D was introduced to describe fatigue crack retardation behavior and a random variable, Z to describe the variability of fatigue crack growth. The retardation coefficient was separately formulated according to retardation behavior which is composed of delayed retardation part and retardation part. The random variable, Z was evaluated from experimental data which was obtained from fatigue crack growth tests under constant amplitude load. Using these variables, a probabilistic model was developed on the basis of the modified Forman's equation, and retardation behavior and cycles were predicted under certain overload condition. The predicted retardation curve well agrees with the trend of experimental crack retardation behavior. And this model well predicts the scatter of experimental retardation cycles.

Effects of Planting Dates on Growth and Yield of Soybean Cultivated in Drained-Paddy Field

  • Cho Jin-Woong;Lee Jung-Joon;Kim Choong-Soo
    • KOREAN JOURNAL OF CROP SCIENCE
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    • v.49 no.4
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    • pp.325-330
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    • 2004
  • This study was carried out to determine adequate planting date, to compare the growth characteristics between early and late maturing cultivars, and to provide the data for the cultivation techniques of soybean [Glycine max (L.) Merr.] in double cropping system with winter crops on paddy field in Korea. Cultivars were planted on 26 May, 16 June, and 7 July with a planting density of $70cm(row\;widtb)\;{\times}\;10cm$ (planting spacing). Seed yield of soybean planted on June 16 and July 7 was approximately $37\%\;and\;53\%$, respectively, less than that of conventional planting date of May 26 in Pungsan-namulkong, and planted on June 16 and July 7 was about $30\%\;and\;37\%$, respectively, less then that of conventional planting date of May 26 in Hanamkong. The number of pods and seeds per plant decreased as planting date delayed. Seed weight increased in Pungsan-namulkong but decreased in Hannamkong as planting date delayed. The flowering date was late in delayed planting plots, but it was shorted for days from emergence to flowering and from emergence to maturity. The plant height of Hannamkong was greater than Pungsan-namulkong from the emergence to flowering stages, but in contrast, it was greater in Pungsan-namulkong than Hannamkong after flowering stage (50d after emergence) when it planted on May 26. There were no significant differences between two soybean cultivars at planting dates of June 16 and July 7. Leaf number, leaf area, and dry matter were also reduced by late planting, and Both of them were shown in high reduction at the later planting. There was a high significant difference at the flowering $(r\;=\;0.87^{**})$ and pod formation $(r\;=\;0.91^{**})$ stages between leaf dry matter and seed yield. Crop growth rate (CGR) was greater at $R2\~R3$ growth stages compared to $R3\~R4\;or\;R4\~R5$ growth stages in two soybean cultivars and the greatest CGR was obtained at planting date of May 26 in two soybean cultivars except for R4-R5 growth stage in Pungsan-namulkong. There was a highly significant positive difference between the seed yield and the leaf area index (LAI) across R3 to R4 and R2 to R3 stages. The photosynthetic rate $(P_N)$ of the uppermost leaf position had no significant difference among planting dates and between two soybean cultivars. However, $P_N$ of the $7^{th}$ leaf position increased as the planting date delayed.

The Growth Characteristics and Yield of Treatment Onion (Allium cepa L.)Seed in Direct Sowing Cultivation (종자처리 양파(Allium cepa L.)의 포장직파재래 생육 특성)

  • 이성춘
    • Korean Journal of Plant Resources
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    • v.14 no.2
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    • pp.94-101
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    • 2001
  • This study was intended to evaluate the relationship environmental condition and growth characteristics of seed treatment seed in direct sowing with different sowing date, and to suggest new cultivation model. The emergence percentage and hours were down as the delayed sowing date. Optimum sowing time was Sep. 10, and sowing must end before Sep. 20 for safety yield. When did sowing ended before Sep.20 in direct sowing cultivation, the seedling growth(SG) and No of roots of direct sowing seedling were larger than transplanting cultivation . At March 8 evaluated seedling, the SG of direct sowing seedling was higher than transplanting, and at Sep. 2(1 those were similar. The missing plant rate in transplanting cultivation was under 3 %, and that in direct sowing cultivation was about 13∼18%, and the extent were sever as delayed sowing date. The bulb fresh weight was decreased as delayed sowing, and those in direct sowing and transplanting cultivation were 230, 217g, respectively. The blot rate was high in direct sowing cultivation, and that was decreased as delayed sowing. The yield in direct sowing and transplanting cultivation were 5,134, 5,300kg, respectively, and those were decreased as delayed sowing. The average yield in early and medium-late maturity cultivars were 3,750, 4,908kg, respectively, and Sonic was highest yield in early maturity cultivars and Nongwoodego was highest in medium-late maturity cultivars. The emergence weed were 9 species as Loportea bulbifera Weddell and others, and Loported bulbifera Weddell, Digitaria violascens Link and Persicaria longiseta Kitagawa were dominant species in direct sowing cultivation with black hole vinyl mulching

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Influence of Delaying Winter Pruning on Shoot Growth and Fruit Quality of 'Fuji'/M.9 Apple Tree (동계전정 지연이 '후지'/M.9 사과나무의 신초생장 및 과실품질에 미치는 영향)

  • Kweon, Hun-Joong;Sagong, Dong-Hoon
    • Korean Journal of Environmental Agriculture
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    • v.41 no.3
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    • pp.199-205
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    • 2022
  • BACKGROUND: The freezing injury by pruning can be reduced by suspending pruning work when severe cold weather (-23 to -49℃) is forecast. Minimum air temperature of the study area, Gunwi region at February 3, 2012 was -21.9℃, and the subzero temperature continued until April 8, 2012. This study was conducted in two years to investigate the effect of delaying winter pruning until full bloom on shoot growth and fruit quality of 'Fuji'/M.9 apple trees. METHODS AND RESULTS: The time of pruning were March 26 for dormant, April 3 for bud break, and May 2 for full bloom. The winter pruning at full bloom significantly reduced fruit weight for two years compared with the control (winter pruning at dormant), and shoot growth was reduced only in the following year. There was no significant effect of delaying winter pruning at bud break on soluble solid content, fruit red color, return bloom, and pruning weight for two years compared with the control. CONCLUSION(S): These results indicated the delaying winter pruning at bud break of 'Fuji'/M.9 apple tree did not offer any disadvantage over comparable dormant pruning, since the fruit quality was not affected. The delayed pruning at full bloom resulted in decreased fruit weight, though shoot growth, fruit quality, and return bloom were not affected by the delayed pruning. So, the delayed pruning should be considered carefully only for the fruit tree orchards in diseases.

The Application of Early-maturing Corn to Cropping System of Forrage Crop I. The late-sowing adaptability of corn varieties requiring the short period to maturing (조숙 옥수수에 의한 사료작물 작부체계 구성 I. 조숙 옥수수 품종의 만파적응성)

  • 임근발;양종석;한흥전;최영원
    • Journal of The Korean Society of Grassland and Forage Science
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    • v.11 no.2
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    • pp.137-142
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    • 1991
  • For the constitution of forage cropping system including the double-cropping of corn, attention has been directed towards the early and short maturing varieties of corn such as Comet 80, Comet 85 and Linda as a component forage crop of forage cropping system. Four corn varieties, Comet 80, Comet 85, Linda and Suwon 19 were planted delayedly by each of 45, 55 and 65 days from the recommended sowing date of suwon 19. Under these condition, growth characteristics and late-sowing adaptability of 4 corn varieties were investigated, and the results are summarized as follows; 1. The variety of suwon 19 did not reach the stage of silking in the occasion of late sowing by 50 days from the optimum sowing time for mono cropping of suwon 19. However early varieties such as Comet 80, Comet 85 and Linda silked under the condition of 65 days-delayed sowing from the recommended sowing time of Suwon 19 for mono-cropping. 2. Early varieties of Comet 80, Comet 85 and Linda were so grown by approximately 92% in plant height, 66% in ear height, 88% in stem diameter and 81% in leaf number respectively compared to Suwon 19 at each of three delayed sowing time that exhibited the dwarfish appearance of canopy. 3. Days from sowing to silking decreased as the sowing time was delayed and the average days from sowing to silking in the sowing treatments of 55 days-delayed of Suwon 19, Comet 80, Comet 85 and Linda were 61, 46, 47 and 51 days, respectively. 4. The size of variations of plant height and ear height influenced by delayed-sowing time was comparatively larger in the varieties of Suwon 19 and Linda than in those of Comet 80 and Comet 85. 5. As sowing time was delayed from the optimum sowing time of Suwon 19 for mono-cropping, ear content decreased from 0% of Suwon 19 at 55 day-delayed sowing treatment to 3540% of Comet 80 and Comet 85 at 65 days-delayed sowing treatment.

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Differential gene expression profiles of periodontal soft tissue from rat teeth after immediate and delayed replantation: a pilot study

  • Chae, Yong Kwon;Shin, Seo Young;Kang, Sang Wook;Choi, Sung Chul;Nam, Ok Hyung
    • Journal of Periodontal and Implant Science
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    • v.52 no.2
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    • pp.127-140
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    • 2022
  • Purpose: In dental avulsion, delayed replantation usually has an uncertain prognosis. After tooth replantation, complex inflammatory responses promote a return to periodontal tissue homeostasis. Various types of cytokines are produced in the inflammatory microenvironment, and these cytokines determine the periodontal tissue response. This study aimed to identify the gene expression profiles of replanted teeth and evaluate the functional differences between immediate and delayed replantation. Methods: Maxillary molars from Sprague-Dawley rats were extracted, exposed to a dry environment, and then replanted. The animals were divided into 2 groups according to the extra-oral time: immediate replantation (dry for 5 minutes) and delayed replantation (dry for 60 minutes). Either 3 or 7 days after replantation, the animals were sacrificed. Periodontal soft tissues were harvested for mRNA sequencing. Hallmark gene set enrichment analysis was performed to predict the function of gene-gene interactions. The normalized enrichment score (NES) was calculated to determine functional differences. Results: The hallmark gene sets enriched in delayed replantation at 3 days were oxidative phosphorylation (NES=2.82, Q<0.001) and tumor necrosis factor-alpha (TNF-α) signaling via the nuclear factor kappa light chain enhancer of activated B cells (NF-κB) pathway (NES=1.52, Q=0.034). At 7 days after delayed replantation, TNF-α signaling via the NF-κB pathway (NES=-1.82, Q=0.002), angiogenesis (NES=-1.66, Q=0.01), and the transforming growth factor-beta signaling pathway (NES=-1.46, Q=0.051) were negatively highlighted. Conclusions: Differentially expressed gene profiles were significantly different between immediate and delayed replantation. TNF-α signaling via the NF-κB pathway was marked during the healing process. However, the enrichment score of this pathway changed in a time-dependent manner between immediate and delayed replantation.

CELLULAR AND MOLECULAR CHARACTERIZATION OF ADENOID CYSTIC CARCINOMA OF THE SALIVARY GLANDS (침샘 선양낭성암종의 세포학적, 분자생물학적 특성에 관한 연구)

  • Park, Young-Wook
    • Maxillofacial Plastic and Reconstructive Surgery
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    • v.27 no.2
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    • pp.110-122
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    • 2005
  • Adenoid cystic carcinoma (ACC) of salivary glands has a protracted clinical course with perineural invasion, delayed onset of hematogenous metastasis, and poor responses to classical cytotoxic chemotherapic agents. Most deaths from salivary ACC are caused by lung metastases that are resistant to conventional therapy. Therefore, knowledge of cellular properties and tumor-host interactions that influence the dissemination of metastatic cells is important for the design of more effective therapy of salivary cancer. I determined in vitro expression of epidermal growth factor receptor (EGFR) and its downstream effectors and vascular endothelial growth factor receptor (VEGFR)-2 on a human salivary ACC cell line (ACC2). I also evaluated the expression of EGF and VEGF signaling molecules and metastasis-related proteins on human salivary ACC cells orthotopically growing in nude mice. In Western blot and immunohistochemical analyses, EGFR and VEGFR-2 were presented and phosphorylated in ACC2 cells. In human parotid cancer xenografts in nude mice, EGF and VEGF signaling molecules, IL-8, and MMP-9 were expressed at markedly higher levels than in normal parotid tissues. Moreover, tumor-associated endothelial cells of this orthotopic parotid tumor expressed phosphorylated VEGFR-2 and phosphorylated Akt, which is a cell-survival protein. These data show that those biomarkers can be molecular targets for therapy of salivary ACC, which has a propensity for delayed lung metastasis.

Effect of Mulching Materials on Growth and Flowering of Oriental Hybrids Lilies in Alpine Area (피복재료가 고랭지 재배 Oriental 백합의 생장과 개화에 미치는 영향)

  • Hong, Sae Jin;Kim, Hak Ki;Park, Se Won
    • Horticultural Science & Technology
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    • v.19 no.4
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    • pp.585-590
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    • 2001
  • Bulbs of Lilium Oriental hybrids cv. 'Casablanca' and 'Marco Polo' were grown in a plastic house in alpine area of Pyongchang Kangwondo. Saw-dust, black film, reflective film, transparent film, and white/black double film were used as mulching materials to ascertain the growth of foliage, the quality of flower, and the size of bulbs. Foliage weights of both lilies were higher when lilies were grown with mulching materials than control. There were no differences of bulb weight among the control and mulching treatments, except delayed bulb growth in black film and white/black double film. Mulching cultivation with saw-dust and reflective film stimulated foliage growth, root growth and bulb production, but black film delayed the growth and development. Transparent and white/black double films showed no effects on foliage growth and bulb development than the control. As mulching materials tended to delay lily growth, including foliage and bulb, an extension of growing term might be better to produce high quality lilies than common cultivation in alpine area.

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