• Title/Summary/Keyword: Deformities

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Regulation of methionine biosynthesis in plants; transgenic study

  • Kim, Jungsup;Thomas Leustek
    • Proceedings of the Botanical Society of Korea Conference
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    • 2002.04a
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    • pp.73-82
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    • 2002
  • The committing step in Met and S-adenosyl-L-methionine (SAM) synthesis is catalyzed by cystathionine ${\gamma}$ -synthase (CGS). Transgenic Arabidopsis thaliana overexpressing CGS under control of 35S promoter show increased soluble Met and its metabolite S-methylmethionine, but only at specific stages of development. CGS-overexpressing seedlings are resistant to ethionine. Similar results were obtained with transgenic potato plants overexpressing Arabidopsis CGS. Several of the transgenic lines show silencing of CGS resulting in deformed p]ants with a reduced capacity for reproductive growth similar as transgenic plants by antisense RNA (CGS[-]). Exogenous feeding of Met to the CGS[-] and CGS[+] silenced plants partially restores their growth. Similar morphological deformities are observed in plants cosuppressed for SAM synthetase, even though such plants accumulate 250 fold more soluble Met than wild type and they overexpress CGS. The results suggest that the abnormalities associated with CGS and SAM synthetase silencing are due in part to a reduced ability to produce SAM, and that SAM may be a regulator of CGS expression.

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Revisited Straight Line Technique for Unilateral Cleft Lip (구순구개열 환자에 있어 직선봉합법의 역할)

  • Seo, Byoung-Moo
    • Korean Journal of Cleft Lip And Palate
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    • v.11 no.1
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    • pp.31-36
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    • 2008
  • The variations of cleft lip deformities imposed the difficulty to the surgical correction for them. Straight line technique for cleft lip surgery has been ignored quite long since other techniques were developed. Initially the straight line technique was introduced and widely accepted because it is simple and easy to perform during the period of no adequate anesthetics. But it was abandoned for its several shortcomings such as tighten lip, vermilion notching, anatomical distortion, and wound contractures. Recently, some groups advocated the usefulness of straight line technique which has a significant modification from its original form. Additionally the variable degree of cleft lip deformity allows simple straight line closure for those patients. Here a case of simple straight line technique was presented and discussed for its reliability and plausible results as well.

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A Study of Exercise treatment based on Schroth method of Idiopathic Scoliosis (특발성 척추 측만증(Idiopathic Scoliosis)애 대한 Schroth 운동요법에 대한 고찰)

  • Yeom, Do-Sung;Song, Yun-Kyung;Lim, Hyung-Ho
    • The Journal of Churna Manual Medicine for Spine and Nerves
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    • v.5 no.2
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    • pp.181-191
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    • 2010
  • Current treatment for adolescent idiopathic scoliosis(AIS) consists of three phases: observation, bracing, and surgery. Although there are many nonsurgical treatment(bracing, electrical stimulation, exercise, manipulation, acupuncture, etc), their effect is still controversial. In many paper, Schroth method was reported good immediate response to conservative care, which could be considered a sign of good prognosis. Schroth method became effective thai specialists in physiotherapy for spinal deformities teach the patient how to perform a routine of 'curve pattern' specific exercises with the purpose to facilitate the correction of the asymmetric posture and to teach the patient to maintain the corrected posture in dally activities. This Principles of correction exercise treatment are based on those developed by the German physiotherepist K. Schroth.

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Treatment of Recurrent Hallux Valgus after Surgery (무지외반증의 수술 후 재발에 대한 치료)

  • Kwon, Ki Bum;Lee, Kyoung Min
    • Journal of Korean Foot and Ankle Society
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    • v.23 no.4
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    • pp.149-153
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    • 2019
  • Recurrence is a common complication following hallux valgus surgery. The postoperative recurrence rates have been reported to be between 2.7% and 16%. Reoperation is considered only for the recurrent deformities with intractable pain. The success of reoperation depends on identifying and addressing the cause of the recurrence appropriately. The surgical principle of reoperation for a recurrent hallux valgus is similar to that of the primary surgery, but arthrodesis and proximal metatarsal osteotomies with greater correcting power are adopted more frequently.

Conservative surgical approach to aggressive benign odontogenic neoplasm: a report of three cases

  • Kumar, Vijay
    • Journal of the Korean Association of Oral and Maxillofacial Surgeons
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    • v.41 no.1
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    • pp.37-42
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    • 2015
  • Aggressive benign odontogenic neoplasms have substantial potential to grow to an enormous size with resulting bone deformities, and they often invade adjacent tissues and spread beyond their normal clinical and radiographic margins; as such, they have a high rate of recurrence. Historically, management (conservative versus aggressive) on the basis of clinical, radiographic and/or histopathologic characteristics has been controversial. However, recent advances in the understanding of the biological features of these lesions may provide greater evidence of the benefits of conservative management. Three patients with different complaints and final histopathologic diagnoses were enrolled in the study. All three cases were treated by a single operator with similar conservative surgical procedures. During follow-up, the patients had uneventful secondary healing and bone regeneration, less packing time than previously reported, no clinical or radiographic evidence of recurrence and no apparent deformity. The aggressive behavior of these lesions requires long clinical and radiographic follow-up. Conservative surgical management may be an option to reduce recurrence and morbidity and increase the probability of uneventful secondary healing and bone regeneration.

The Straight Line Repair for Unilateral Incomplete Cleft Lip - Cases report and journal review (편측성 불완전 구순열의 직선 봉합법에 의한 수복 - 증례 보고 및 문헌고찰)

  • Kim, Hak-Kyun;Kim, Jae-Jin;Kim, Eun-Suk
    • Korean Journal of Cleft Lip And Palate
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    • v.11 no.2
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    • pp.77-82
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    • 2008
  • The harmonious lip length, residual scar and Cupid's bow width and peak with a normal side are the aims of a unilateral cleft lip repair. Also, long term amelioration without necessary of revisional surgeries may be the ideal conditions. No one method can satisfy the wide varieties of cleft lip deformities. Recently with rearrangement of paraoral muscle and some modifications, a straight line repair technique has been concerned again. Straight scar line, simplicity, and short learning curve are the advantages of the straight line technique. Here two cases of the simple straight line technique were presented and discussed for its usefulness and reliability with short reviews of previous reports.

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Craniofacial Centre of Children's Hospital Boston and Sequential Management for Cleft Lip and Palate (Children's Hospital Boston의 Craniofacial Centre와 구순구개열 환자의 순차적 치료순서)

  • Jung, Young-Soo
    • Korean Journal of Cleft Lip And Palate
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    • v.11 no.2
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    • pp.59-63
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    • 2008
  • Craniofacial Centre at Children's Hospital Boston is a worldwide leader in the care of children and adolescents with craniofacial anomalies especially with cleft lip and/or cleft palate, which provides a team approach to the evaluation, diagnosis and treatment of children and adults with congenital (present at birth) or acquired facial deformities. This is staffed by an experienced team of clinicians, such as in oral and maxillofacial surgery, plastic surgery, neurosurgery, dentistry, audiology, speech and language pathology, genetics, psychiatry, otolaryngology, and social work, all with specialized training in the care of children with craniofacial anomalies. Here, there is a short introduction of history, attending surgeons, works, and sequential treatment for cleft lip/palate patients about this institution.

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A Case of Microtia (선천성 외이기형)

  • 김세훈;원상희;황명순;한주호;김선우
    • Proceedings of the KOR-BRONCHOESO Conference
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    • 1981.05a
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    • pp.40.2-40
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    • 1981
  • The deformities of the auricle is rare and classified roughly into two categories as "Hyperplasia and Hypoplasia". Microtia occurs about once in every 6000 births and is twice as frequent in males as in females and the unilateral to bilateral ratio is roughly 8 : 1. Significant malformation of the auricle frequently involves the external auditory canal and the contents of the middle ear. Recently, the authors experienced a case of hypoplasia of the superior third of the right auricle of 24 year old male, with neither hearing impairment nor any other associated defect, who was surgically corrected by rotation flaps through post-auricular incision.

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The review of literature;Treatment of a clavus with Fructus mume(烏梅) (("오매(烏梅)의 티눈치료(治療)" 에 관(關)한 문헌고찰(文獻考察))

  • Pang, Jong-Ki
    • Journal of the Korean Institute of Oriental Medical Informatics
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    • v.14 no.1
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    • pp.43-54
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    • 2008
  • The term keratosis covers a variety of growths such as warts and pressure-induced callosities. Warts develop in the absence of pressure, and often clear up again after a certain period, usually without treatment. Clavi can develop as a result of wearing poorly fitting shoes, but also deformed toes or other anatomical deformities affecting the foot. The resulting non-anatomical stressing leads to the formation of pressure callosities and even to pressure sores. It confronts hereupon, it searched the cure against the clavus with fructus mume(烏梅) and it arranged. The possibility of getting the result regarding the clavus treatment with fructus mume(烏梅) from the oriental medicine it was.

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