• 제목/요약/키워드: Defense Response

검색결과 784건 처리시간 0.027초

Molecular Mechanisms Involved in Bacterial Speck Disease Resistance of Tomato

  • Kim, Young-Jin;Gregory B. Martin
    • The Plant Pathology Journal
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    • 제20권1호
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    • pp.7-12
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    • 2004
  • An important recent advance in the field of plant-microbe interactions has been the cloning of genes that confer resistance to specific viruses, bacteria, fungi or insects. Disease resistance (R) genes encode proteins with predicted structural motifs consistent with them having roles in signal recognition and transduction. Plant disease resistance is the result of an innate host defense mechanism, which relies on the ability of plant to recognize pathogen invasion and efficiently mount defense responses. In tomato, resistance to the pathogen Pseudomonas syringae pv. tomato is mediated by the specific recognition between the tomato serine/threonine kinase Pto and bacterial protein AvrPto or AvrPtoB. This recognition event initiates signaling events that lead to defense responses including an oxidative burst, the hypersensitive response (HR), and expression of pathogenesis- related genes.

The influence of load pulse shape on pressure-impulse diagrams of one-way RC slabs

  • Wang, Wei;Zhang, Duo;Lu, Fangyun
    • Structural Engineering and Mechanics
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    • 제42권3호
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    • pp.363-381
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    • 2012
  • This study is aimed at providing an efficient analytical model to obtain pressure- impulse diagram of one-way reinforced concrete slabs subjected to different shapes of air blast loading using single degree of freedom method (SDOF). A tri-linear elastic perfectly plastic SDOF model has been used to obtain the pressure-impulse diagram to correlate the blast pressure and the corresponding concrete flexural damage. In order to capture the response history for the slab, a new approximately SDOF method based on the conventional SDOF method is proposed and validated using published test data. The influences of pulse loading shape on the pressure-impulse diagram are studied. Based on the results, a pressure-impulse diagram generation method using SDOF and an analytical equation for the pressure-impulse diagram is proposed to different damage levels and different blast loading shapes.

Close Surface Targets Detection using Background Removal Integral Projection in Coastal Environment (배경제거 가산투영 방법을 이용한 근거리 해상 표적 탐지)

  • Lee, Boohwan;Kim, Jieun;Yang, Yu Kyung
    • Journal of the Korea Institute of Military Science and Technology
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    • 제17권1호
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    • pp.115-121
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    • 2014
  • In this paper, we propose a robust background removal integral projection(BRIP) method which can detect close surface targets in coastal environment for IRST. Row pixels of background region from coastal infrared image show similar response. Thus, the proposed BRIP is calculated after horizontal and vertical background estimations and removals are performed sequentially. Finally, surface large targets can be detected using the results of the BRIP. Experimental results on a set of real infrared image sequence show that the proposed method could fully detect ships in every frame.

A Study on Defense and Attack Model for Cyber Command Control System based Cyber Kill Chain (사이버 킬체인 기반 사이버 지휘통제체계 방어 및 공격 모델 연구)

  • Lee, Jung-Sik;Cho, Sung-Young;Oh, Heang-Rok;Han, Myung-Mook
    • Journal of Internet Computing and Services
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    • 제22권1호
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    • pp.41-50
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    • 2021
  • Cyber Kill Chain is derived from Kill chain of traditional military terms. Kill chain means "a continuous and cyclical process from detection to destruction of military targets requiring destruction, or dividing it into several distinct actions." The kill chain has evolved the existing operational procedures to effectively deal with time-limited emergency targets that require immediate response due to changes in location and increased risk, such as nuclear weapons and missiles. It began with the military concept of incapacitating the attacker's intended purpose by preventing it from functioning at any one stage of the process of reaching it. Thus the basic concept of the cyber kill chain is that the attack performed by a cyber attacker consists of each stage, and the cyber attacker can achieve the attack goal only when each stage is successfully performed, and from a defense point of view, each stage is detailed. It is believed that if a response procedure is prepared and responded, the chain of attacks is broken, and the attack of the attacker can be neutralized or delayed. Also, from the point of view of an attack, if a specific response procedure is prepared at each stage, the chain of attacks can be successful and the target of the attack can be neutralized. The cyber command and control system is a system that is applied to both defense and attack, and should present defensive countermeasures and offensive countermeasures to neutralize the enemy's kill chain during defense, and each step-by-step procedure to neutralize the enemy when attacking. Therefore, thist paper proposed a cyber kill chain model from the perspective of defense and attack of the cyber command and control system, and also researched and presented the threat classification/analysis/prediction framework of the cyber command and control system from the defense aspect

Whole-Blood Gene-Expression Profiles of Cows Infected with Mycobacterium avium subsp. paratuberculosis Reveal Changes in Immune Response and Lipid Metabolism

  • Shin, Min-Kyoung;Park, Hong-Tae;Shin, Seung Won;Jung, Myunghwan;Im, Young Bin;Park, Hyun-Eui;Cho, Yong-Il;Yoo, Han Sang
    • Journal of Microbiology and Biotechnology
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    • 제25권2호
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    • pp.255-267
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    • 2015
  • Mycobacterium avium subsp. paratuberculosis (MAP) is the causative agent of Johne's disease, a chronic debilitating disease affecting ruminants worldwide. In the present study, we aimed to determine the major gene networks and pathways underlying the immune response to MAP infection using whole-blood cells, as well as provide the potential transcriptional markers for identifying the status of MAP infection. We analyzed the transcriptional profiles of whole-blood cells of cattle identified and grouped according to the presence of MAP-specific antibodies and the MAP shed by them. The grouping was based on the results obtained by ELISA and PCR analyses as follows: i) Test1 group: MAP-negative results obtained by ELISA and positive results obtained by PCR; ii) Test2 group: MAP-positive results obtained by ELISA and negative results obtained by PCR; iii) Test3 group: MAP-positive results obtained by ELISA and positive results obtained by PCR; iv) uninfected control: MAP-negative results obtained both by ELISA and PCR analysis. The results showed down-regulated production and metabolism of reactive oxygen species in the Test1 group, activation of pathways related to the host-defense response against MAP (LXR/RXR activation and complement system) in the Test2 and Test3 groups, and anti-inflammatory response (activation of IL-10 signaling pathway) only in the Test3 group. Our data indicate a balanced response that serves the immune-limiting mechanism while the host-defense responses are progressing.

Effects of stress induced by changes of water temperature on the non-specific defense mechanism in cultured olive flounder, Paralichthys olivaceus (수온 변동 자극이 양식 넙치, Paralichthys olivaceus의 비특이적 생체 방어에 미치는 영향)

  • Lee, Deok-Chan;Kim, Do-Hyung;Kim, Su-Mi;Kang, Myong-Seok;Hong, Mi-Ju;Kim, Hyun-Jeong;Park, Soo-Il
    • Journal of fish pathology
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    • 제15권2호
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    • pp.65-75
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    • 2002
  • This study was performed to know the effects of stress induced by the daily fluctuation of water temperture from 18$^{\circ}C$ to 25$^{\circ}C$ up and down for 30 days on the defence mechanism of olive flounder. Puralichthys olivaceus. To make clear the temperature stress on the defense mechanism of the tested fish. several factors of immune response such as counting of leucocyte appearance in peripheral blood, phagocytic activity in whole blood cells, nitroblue tetrazolium(NBT) reduction, chemiluminescence(CL) response, and lysozyme activity were investigated at 28 days after giving the change of water temperature. The fish was controlled under the none feeding condition during experimental period. Mortality of the tested fish was rapidly increased up to 22% within the first one week of the experimental period without any additional stress factors. The number of neutrophil of peripheral blood in the tested group was significantly higher than the control group at the 2nd week. but the number of lymphocyte was significantly lower than the control group at the 1st and 3rd day of the experimental period. respectively. In the NBT reduction test, the activity of macrophage in the control group fish was the highest on the 7th day while that in the tested group was on the 3rd day. Also. the phagocytosis of tested group against formalin killed cells was retarded compared with the control. CL response of the tested group was significantly lower from 2nd to 5lh day of the experimental period than the control. 'The lysozyme activity of tested group was remained higher during the experimental period than the control. Even though the tested fish showed different results in some non-specific factors of immune respceses between tested and control group fish, olive flounder seems highly adaptable in repealed water temperature change in condition after one week under the given temperature fluctuation range.

Tobamovirus Coat Protein CPCg Induces an HR-like Response in Sensitive Tobacco Plants

  • Ehrenfeld, Nicole;Canon, Paola;Stange, Claudia;Medina, Consuelo;Arce-Johnson, Patricio
    • Molecules and Cells
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    • 제19권3호
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    • pp.418-427
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    • 2005
  • When inoculated into sensitive tobacco Xanthi-nn plants, the crucifer and garlic-infecting Tobacco mosaic virus (TMV-Cg) induces local necrotic lesions that resemble those seen in the hypersensitive response (HR) of resistant tobacco plants. However, unlike these, tobacco Xanthi-nn plants do not become resistant to infection and the virus spreads systemically causing a severe disease characterized by necrotic lesions throughout the plant. To identify the viral protein that elicits this necrotic response, we used a set of hybrid viruses constructed by combination of TMV-Cg and the tobacco mosaic virus strain U1 (TMV-U1). In this study we present evidence that the coat protein of TMV-Cg (CPCg) is the elicitor of the necrotic response in tobacco Xanthi-nn plants. Local and systemic necrotic lesions induced by TMV-Cg and by the hybrid U1-CPCg -that carries CPCg in a TMV-U1 context- are characterized by cell death and by the presence of autoflorescent phenolic compounds and $H_2O_2$, just like the HR lesions. In addition, defense-related genes and detoxifying genes are induced in tobacco Xanthi-nn plants after TMV-Cg and U1-CPCg inoculation. We postulate that in our system, CPCg is recognized by sensitive tobacco plants that mount an incomplete defense response. We call this an HR-like since it is not enough to induce plant resistance.

A Study on Spotlight SAR Image Formation by using Motion Measurement Results of CDGPS (CDGPS의 요동 측정 결과를 이용한 Spotlight SAR 영상 형성에 관한 연구)

  • Hwang, Jeonghun;Ko, Young-Chang;Kim, So-Yeon;Kwon, Kyoung-Il;Yoon, Sang-Ho;Kim, Hyung-Suk;Shin, Hyun-Ik
    • Journal of the Korea Institute of Military Science and Technology
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    • 제21권2호
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    • pp.166-172
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    • 2018
  • To develop and evaluate the real-time SAR(Synthetic Aperture Radar) motion measurement system, true antenna phase center(APC) positions during SAT(Synthetic Aperture Time) are needed. In this paper, CDGPS(Carrier phase Differential Global Positioning System) post processing method is proposed to get the true APC position for spotlight SAR image formation. The CDGPS position is smoothed to remove high frequency noise which exists inherently in the carrier phase measurement. This paper shows smoothed CDGPS data is enough to provide the true APC for high-quality SAR image formation through motion measurement result, phase error estimation and IRF(Impulse Response Function) analysis.

A Study on Maturity Model for the Assessment of Cyber Resilience Level in the Defence Information System (국방정보시스템 사이버복원력 수준 평가를 위한 성숙도모델에 관한 연구)

  • Choi, Jae-hyeok;Kim, Wan-ju;Lim, Jae-sung
    • Journal of the Korea Institute of Information Security & Cryptology
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    • 제29권5호
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    • pp.1153-1165
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    • 2019
  • Recently, threats of hacking have been increasing on the national intelligence service network and key infrastructure, including the defense field. The defense information system responds to threats from the outside through the network separation, but if the defense information system is hacked, it has a serious impact on the operations of wartime or peacetime military forces. Today, cyberattacks and threats are rising to unpredictable levels and making it practically impossible to completely block and prevent hacking threats completly. So, in this study proposed a maturity model to assess the level of cyber-resilience, which is the ability to ensure the system's viability and maintain continuity through rapid response and recovery if signs of cyberattacks by the defense information system are expected or occurred. The proposed maturity model is expected to contribute to improving the cyber security level of the defense information system by assessing the level of cyber resilience of the defense information system and identifying and supplementing fields that are lacking.

Improving the Security Policy Based on Data Value for Defense Innovation with Science and Technology (과학기술 중심 국방혁신을 위한 데이터 가치 기반 보안정책 발전 방향)

  • Heungsoon Park
    • Convergence Security Journal
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    • 제23권1호
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    • pp.109-115
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    • 2023
  • The future outlook for defense faces various and challenging environments such as the acceleration of uncertainty in the global security landscape and limitations in domestic social and economic conditions. In response, the Ministry of National Defense seeks to address the problems and threats through defense innovation based on scientific and technological advancements such as artificial intelligence, drones, and robots. To introduce advanced AI-based technology, it is essential to integrate and utilize data on IT environments such as cloud and 5G. However, existing traditional security policies face difficulties in data sharing and utilization due to mainly system-oriented security policies and uniform security measures. This study proposes a paradigm shift to a data value-based security policy based on theoretical background on data valuation and life-cycle management. Through this, it is expected to facilitate the implementation of scientific and technological innovations for national defense based on data-based task activation and new technology introduction.