• 한국산학기술학회논문지
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• 제13권3호
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• pp.1203-1211
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• 2012

본 연구의 목적은 직업유무에 따라 노인의 건강상태, 수면 및 우울을 비교하고, 건강상태와 수면이 우울과 관련이 있는지를 파악하는 것이다. 본 연구는 보건복지가족부가 실시한 "2008 노인실태조사"의 자료를 사용하였으며, 총 조사대상자 15,146명 중 직업이 있는 노인 5,204명과 직업이 없는 노인 9,942명이 최종분석에 이용되었다. 연구결과에 따르면 직업 유무에 따라 건강상태, 수면 및 우울에 유의한 차이가 있었다. 직업이 있는 노인의 경우 직업만족도가 우울에 가장 큰 영향을 미치는 요인으로 나타났으며, 주관적 건강상태, 현재 질병으로 인한 일상생활의 어려움 정도, 숙면을 취한 일수 순서로 유의한 영향을 미치는 것으로 나타났다. 이 변수들의 우울에 대한 설명력은 29%로 나타났다. 직업이 없는 노인의 경우 주관적 건강상태가 우울에 가장 큰 영향을 미치는 것으로 나타났으며, 현재 질병으로 인한 일상생활의 어려움 정도, 숙면을 취한 일수, 총 수면 시간 순으로 우울에 유의한 영향을 미치는 것으로 파악되었다. 이 변수들의 우울에 대한 설명력은 32%로 나타났다. 그러므로 노인의 건강상태, 수면, 우울을 향상시키기 위한 건강증진 중재는 직업유무에 따른 이러한 차이를 고려하여 계획되고 제공되어야 한다.

• Journal of Dental Anesthesia and Pain Medicine
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• 제17권1호
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• pp.71-76
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• 2017

Drug-induced sleep endoscopy (DISE) is used to identify areas of upper airway obstruction, which occurs when patients with obstructive sleep apnea (OSA) snore. DISE enables effective diagnosis and appropriate treatment of the obstruction site. Among surgical treatment methods for OSA, maxillomandibular advancement surgery (MMA) is performed to move a jaw forward; the surgery has a high success rate for OSA treatment. In DISE, anesthetics such as propofol and midazolam must be administered to induce snoring while the patient is deeply sedated for an accurate diagnosis to be made. When inducing deep sedation in a patient with OSA, airway obstruction may increase, causing oxygen saturation to drop; airway interventions are necessary in such cases. Effective DISE and MMA surgery can be performed by administering propofol through target-controlled infusion while monitoring the bispectral index (BIS).

• 한국보육지원학회지
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• 제18권6호
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• pp.75-99
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• 2022

Objective: This study aims to explore ways to empirically analyze and manage childcare teachers' job stress based on their relationship with stress-related physiological indicators measured by a fitness tracker. Methods: The study participants were 27 childcare teachers in Gyeonggi-do and wore Garmin's wearable fitness tracker Vivosmart 4 for 15 days for three months. The collected information was analyzed for mean, SD, ANOVA, and correlation using JAMOVI 2.00. Results: First, among the daily changes of physiological indicators measured by a fitness tracker, the data collected on Mondays were significant. On Mondays, the stress index was high, the duration of the rest period was short, and the sleep time was short. The stress of childcare teachers showed a significant negative relationship with the body battery which was calculated by considering the duration of the rest period, heart rate variability, stress, and activity level. Also, the duration of deep sleep was positively correlated with a low degree of stress. There was a significant relationship between the childcare teachers' psychological indicators and the biomarkers measured by fitness trackers. Conclusion/Implications: Stress research using a fitness tracker is big data, and in-depth analysis is possible. Fitness trackers can collect and utilize repeated measurement data for each individual childcare teacher.

• 대한두개안면성형외과학회지
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• 제22권6호
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• pp.287-295
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• 2021

Orthognathic surgery has steadily evolved, gradually expanding its scope of application beyond its original purpose of simply correcting malocclusion and the facial profile. For instance, it is now used to treat obstructive sleep apnea and to achieve purely cosmetic outcomes. Recent developments in three-dimensional digital technology are being utilized throughout the entire process of orthognathic surgery, from establishing a surgical plan to printing the surgical splint. These processes have made it possible to perform more sophisticated surgery. The goal of this review article is to introduce current trends in the field of orthognathic surgery and controversies that are under active discussion. The role of a plastic surgeon is not limited to performing orthognathic surgery itself, but also encompasses deep involvement throughout the entire process, including the set-up of surgical occlusion and overall surgical planning. The authors summarize various aspects in the field of orthognathic surgery with the hope of providing helpful information both for plastic surgeons and orthodontists who are interested in orthognathic surgery.

• Journal of Menopausal Medicine
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• 제24권3호
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• pp.183-187
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• 2018

Objectives: The present mini review aimed to summarize the existing knowledge regarding the beneficial and adverse effects of raloxifene in menopausal women. Methods: This study is a review of relevant publications about the effects of raloxifene on sleep disorder, depression, venous thromboembolism, the plasma concentration of lipoprotein, breast cancer, and cognitive function among menopausal women. Results: Raloxifene showed no significant effect on depression and sleep disorder. Verbal memory improved with administration of 60 mg/day of raloxifene while a mild cognitive impairment risk reduction by 33% was observed with administration of 120 mg/day of raloxifene. Raloxifene was associated with a 50% decrease in the need for prolapse surgery. The result of a meta-analysis showed a significant decline in the plasma concentration of lipoprotein in the raloxifene group compared to placebo (standardized mean difference, -0.43; 10 trials). A network meta-analysis showed that raloxifene significantly decreased the risk of breast cancer (relative risk, 0.572; 95% confidence interval, 0.327-0.881; P = 0.01). In terms of adverse effects of raloxifene, the odds ratio (OR) was observed to be 1.54 (P = 0.006), indicating 54% increase in the risk of deep vein thrombosis (DVT) while the OR for pulmonary embolism (PE) was 1.05, suggesting a 91% increase in the risk of PE alone (P = 0.03). Conclusions: Raloxifene had no significant effect on depression and sleep disorder but decreased the concentration of lipoprotein. Raloxifene administration was associated with an increased risk of DVT and PE and a decreased risk of breast cancer and pelvic organ prolapse in postmenopausal women.

• JSTS:Journal of Semiconductor Technology and Science
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• 제8권2호
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• pp.134-138
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• 2008

We present a power gating turn-on mechanism that digitally suppresses ground-bounce noise in ultra-deep submicron technology. Initially, a portion of the sleep transistors are switched on in a pseudo-random manner and then they are all turned on fully when VVDD is above a certain reference voltage. Experimental results from a realistic test circuit designed in 65nm bulk CMOS technology show the potential of our approach.

• 대한임상검사과학회지
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• 제44권2호
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• pp.52-58
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• 2012

Patients with obstructive sleep apnea (OSA) often have more aggravated symptoms in the supine position. We tried to investigate the clinical characteristics and the predictive factors for positional OSA. Polysomnographic data were reviewed for OSA patients (apnea hypopnea index, $AHI{\geq}5$) from April, 2008 to April, 2011 at the Asan Medical Center. Clinical data, comorbid medical condition data and questionnaires (SF-36, MFI-20, ESS, BDI, STAI) were assessed. All patients were classified into two groups: positional patients (PP) group and non-positional patients (NPP) group. PP was defined as a patient who had the AHI in the supine position was at least twice as high as that in the lateral position. The body position of patients was confirmed by sleep position sensor and video monitor. All patients had at least 30 minutes of positional and 30 minutes of non-positional sleep. We compared clinical, medical, polysomnographic data, and questionnaire results between two (PP and NPP) groups and investigated predictive factors for the PP group using binary logistic regression analysis. In total, 371 patients were investigated. 265 (71.4%) was categorized as PP group and 106 (28.5%) as NPP group. The mean age ($mean{\pm}SD$) was higher in the PP group ($52.4{\pm}9.8$) than in the NPP group ($49.5{\pm}11.9$) (p<0.05). Comparison of sleep parameters between the PP and the NPP group showed that the PP group had significantly lower BMI (PP: $26.1{\pm}3.2kg/m^2$; NPP: $27.8{\pm}4.3kg/m^2$, p<0.001), neck circumference (PP: $39.7{\pm}2.8cm$; NPP: $41.5{\pm}3.7cm$, p<0.001) and hypertension rate (PP: n=89/265 (33.5%); NPP: n=48/106 (45.2%), p=0.0240). In the PP group, the percentage of deep sleep (PP: $8.7{\pm}8.1%$; NPP: $5.6{\pm}7.0%$, P=0.001) and rapid eye movement (REM) (PP: $17.5{\pm}6.1%$; NPP: $14.0{\pm}6.9%$, p<0.001) were significantly higher whereas the percentage of light sleep (stage N1) was significantly lower than the NPP group (PP: $30.4{\pm}12.3$; NPP: $44.5{\pm}20.8%$, p<0.001). During the sleep, the AHI in the supine position (PP: $48.6{\pm}19.5$; NPP: $60.5{\pm}22.6$, p<0.001) and in the non-supine position (PP: $9.4{\pm}8.9$; NPP: $48.4{\pm}24.8$, p=<0.001) were significantly lower and the minimal arterial oxygen saturation in non-REM sleep was significantly higher in the PP group (PP: $80.3{\pm}7.6$; NPP: $75.1{\pm}9.9$, p=<0.001). There were no significant differences in all questionnaires including quality of life. The results of the binary logistic regression analysis showed that age, the amount of REM sleep(%) and AHI were significant predictive factors for positional OSA. The significant predictive factors for positional OSA were older age, higher percentage of REM and lower AHI. The questionnaire results were not significantly different between the two groups.

• 한국인터넷방송통신학회논문지
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• 제19권1호
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• pp.153-159
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• 2019

호흡은 환자의 상태를 판단하는 중요한 생체 신호 중 하나이다. 특히 진정 마취 시 환자의 무호흡 및 저호흡은 지속적인 모니터링 없이는 탐지하기가 어렵기 때문에 환자의 호흡 상태를 정확하고 간편하게 판단할 수 있는 지속적인 호흡 모니터링 방법이 필요하다. 현재 호흡 상태의 모니터링을 위한 다양한 장치들이 사용되고 있으나 임상 사용단계에서 응답 시간이 느릴 뿐 아니라 사용에 불편한 단점을 안고 있다. 본 연구에서는 이러한 문제점을 해결하고자 PVDF(polyvinylidene fluoride) 필름을 이용한 부착형 센서와 회로를 설계하고 제작하였으며, 진정 마취 시 호흡 신호를 감지하여 이상 호흡 징후를 조기에 발견할 수 있는 알고리즘을 포함하는 모니터링 시스템을 개발하였다. 본 연구의 결과는 진정 마취 시 뿐만 아니라 수면 관련 호흡 상태의 원격진료를 통한 다양한 의료산업 분야에 적용될 수 있을 것이다.

• Tuberculosis and Respiratory Diseases
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• 제48권6호
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• pp.956-963
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• 2000

연구배경 : 폐쇄성 수면 무호흡증 환자 중 수평와위보다 측와위에서 호흡장애의 정도가 호전되는 체위성 폐쇄성 수면 무호흡증 환자의 신체계측인자와 수면단계 및 수면구조의 특성, 그리고 동맥혈산소포화도의 차이를 수면다원검사를 통하여 확인하고자 하였다. 대상 및 방법 : 1996년부터 1998년까지 수면장애로 영남대학병원에서 수면다원검사를 실시하여 폐쇄성 수면 무호흡증으로 진단된 환자 중 20세 이상으로 체질량지수(BMI) 20 이상, 호흡장애지수(RDI) 10 이상, 수평와위와 측와위로 각각 30분 이상 수면을 취했던 환자 50명을 대상으로 하였다. Cartwright 등의 기준에 따라 체위성, 비체위성 수면 무호흡증으로 구분하였다. 수면 다원 검사와 동맥혈 산소포도를 측정하였고 자동 체위감지 장치와 전문검사자의 관찰로 환자의 체위를 확인하였다. 결과 : 체위성 폐쇄성 수면 무호흡증 환자는 전체 폐쇄성 수면 무호흡증 환자의 30%를 차지하였다. 이들의 신체 계측의 특징은 비체위성 무호흡증 환자와 비교할 때 몸무게는 낮은 경향이 있었고(p>0.05), 체질량지수는 낮았다(p<0.05). 체위성 폐쇄성 수면 무호흡증 환자는 수면효율이 높고(p<0.05), 총 수면시간과 깊은 수면을 나타내는 3, 4 단계의 수면지속 시간은 길었으며(p<0.05), 무호흡지수는 유의하게 낮았다(p<0.05). 또한 수면 중 평균저산소포화도 및 평균산소 포화도, 그리고 최저산소포화도는 각각 87.7%, 92.7%, 78.3%로 비체위성 무호흡증 환자보다 유의하게 높았고(p<0.05), 동맥혈 산소 불포화도 지수는 체위성 무호흡증 환자가 훨씬 낮았다(p<0.05). 결과 : 폐쇄성 수면 무호흡증 환자는 체위에 따라 수면 중 발생하는 호흡장애정도나 무호흡 빈도의 차이가 크고, 체질량지수는 이러한 체위에 따른 호흡양상의 변화에 중요한 역할을 한다. 따라서 일부 폐쇄성 수면 무호흡증 환자의 호흡장애를 개선시키기 위하여 체위치료법과 비만도 조절이 중요하며, 수면다원검사를 시행할때 체위변동 관찰과 체위변동에 따른 수면구조의 변화에 대한 평가가 반드시 필요할 것으로 생각한다.

• 동의신경정신과학회지
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• 제14권1호
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• pp.155-160
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• 2003

The Common Symptoms of insomnia are to be hard to sleep, not to get deep sleep, often wake up at night, be easy not to fall asleep again after waking up. In serious conditions, an insomniac can never get to sleep overnight. Herbal acupuncture therapy is especially used for patients who cannot take an oral medication. Another advantage of herbal acupuncture therapy is immediate effect of the herbal potency which is not destroyed during digestion. One patient who have taken western drugs for long time, was treated with Jahageo herbal acupuncture at BaekRo and AnMyen. effectively his insomnia was regulated. So We consider that Jahageo herbal acupuncture is useful in regulation insomnia.