• Title/Summary/Keyword: Decrease rate

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Effects of Ethanol Administration on Glutathione and Lipid Peroxide Levels in Rat Liver and Cerebellum (에탄을 공급이 흰쥐 조직중의 Glutathione 및 지질산화 수준에 미치는 영향)

  • 이정원
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.20 no.4
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    • pp.285-292
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    • 1991
  • The effects of acute and chronic ethanol administration on hepatic and cerebellar glutathione (GSH) statuses and lipid peroxide levels in rats were investigated. In the liver, chronic ethanol feeding (6.9 g/kg, per day) as 10% (v/v) drinking water for 4 weeks produced a slight decrease of total GSH and an increase in the ratio of GSSG/total GSH without change of GSSG (oxidized GSH). Lipid peroxide level however was not modified. Many other studies have shown the acute ethanol loading effect in the rat liver, that is moderate decrease of total GSH and elevation of lipid peroxide level. Relating to this, it was observed that total GSH in the plasma obtained from post. hepatic inferior vena cava was increased by acute ethanol injection (50 mmol/kg, i.p.). This increased hepatic efflux of GSH into blood, in addition to the promoted antioxidative utilization of GSH, could be suggested as one of the possible reasons for the decrease of hepatic GSH induced by ethanol load. In the cerebellum, acute ethanol load did not change the total GSH and GSSG, but increased the lipid peroxidation rate. In the chronic, neither GSH pattern nor lipid peroxidation rate was changed.

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Reactions and Properties of a RT-Castable PU Elastomer Modified with Oligomeric Diol (올리고머형 디올로 개질된 상온주형용 PU 엘라스토머의 반응과 물성)

  • Ahn, Won-Sool;Kim, Hoon-Seop
    • Elastomers and Composites
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    • v.43 no.1
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    • pp.18-24
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    • 2008
  • An oligomeric diol was utilized as a modifier for the reaction rate and mechanical properties of a RT-castable polyurethane elastomer. Both the reaction rate and the tensile strength of the blend samples, in which the modifier and the base resins were mixed with one-shot method, showed an exponential decrease as the increase of modifier concentration. Thermal analysis method of Kissinger was also effectively applied in the present study, showing good linearity in the plot of ln $(q/T^2_p)$ vs. $(1/T_p)$ and activation energy $E_a$ of 44.80 kJ/mol, which is similar to the general castable polyurethane. In the mechanical properties, remarkable decrease of strength was found by the addition of modifier concentration range up to about 20 phr, while characteristic elongation property of the elastomer, high elongation at lower strength, was observed over 20 phr of the modifier. Exponential decrease of the break strength of the blend sample exhibited that the mechanical properties of the blend might be considerably sensitive to the modifier concentration.

Time Course of Ventricular Remodeling after Atrial Septal Defect Closure in Adult Patients

  • Bae, Yo Han;Jang, Woo Sung;Kim, Jin Young;Kim, Yun Seok
    • Journal of Chest Surgery
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    • v.54 no.1
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    • pp.45-52
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    • 2021
  • Background: Atrial septal defect (ASD) is the most common congenital heart disease. However, the details of cardiac chamber remodeling after surgery are not well known, although this is an important issue that should be analyzed to understand long-term outcomes. Methods: Between November 2017 and January 2019, cardiac magnetic resonance imaging was performed preoperatively, at a 1-month postoperative follow-up, and at a 1-year postoperative follow-up. Cardiac chamber volume, valve regurgitation volume, and ejection fraction were measured as functions of time. Results: Thirteen patients (10 men and 3 women) were included. The median age at surgery was 51.4 years. The preoperative median ratio of flow in the pulmonary and systemic circulation was 2.3. The preoperative mean right ventricular (RV) end-diastolic volume index (EDVi) and RV end-systolic volume index (ESVi) had significantly decreased at the 1-month postoperative follow-up (p<0.001, p=0.001, respectively). The decrease in the RVEDVi (p=0.085) and RVESVi (p=0.023) continued until the postoperative 1-year follow-up, although the rate of decrease was slower. Tricuspid valve regurgitation had also decreased at the 1-month postoperative follow-up (p=0.022), and continued to decrease at a reduced rate (p=0.129). Although the RVEDVi and RVESVi improved after ASD closure, the RV volume parameters were still larger than the left ventricular (LV) volume parameters at the 1-year follow-up (RVEDVi vs. LVEDVi: p=0.016; RVESVi vs. LVESVi: p=0.001). Conclusion: Cardiac remodeling after ASD closure is common and mainly occurs in the early postoperative period. However, complete normalization does not occur.

Impacts of Population Aging on Real Interest Rates (인구 고령화가 실질 금리에 미치는 영향)

  • Kim, Myunghyun;Kwon, Ohik
    • Economic Analysis
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    • v.26 no.1
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    • pp.133-166
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    • 2020
  • Since the mid-1990s, Korea has been aging rapidly. At the same time, real interest rates have declined sharply. This paper studies whether population aging has contributed to the real interest rate decrease in Korea. We first present empirical evidence that increases in life expectancy and the old-age-dependency ratio, and a fall in population growth, i.e., the population aging, decrease real interest rates. Then we calibrate a life-cycle model to capture the features of the old-age-dependency ratio and population growth in Korea, and show that population aging accounts for about one third of the fall in real interest rates between 1995 and 2018. Furthermore, according to simulation results, increased life expectancy is more important than decreased population growth in affecting the real interest rate decrease during the period.

Analysis about relation of Won/Dollar Foreign Exchange Rate and Interest Rate of Korea (한국 원/달러환율과 금리의 관계분석)

  • 김종권
    • Journal of Korean Society of Industrial and Systems Engineering
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    • v.21 no.48
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    • pp.133-144
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    • 1998
  • International capital movement has made progress at global liberalization of finance and foreign exchange, international monetary norm changing into floating exchange rate system, easiness of collection of information and trade at improvement of information communication technology from early of 1970's. Results of empirical test for relation between foreign exchange rate or various determination factors of foreign exchange rate and interest rate are followed by next sentences. First, according to relation between foreign exchange rate and interest rate, correlation for each of variables after OECD entrance is increased. But, long-term & short-term interest rate is affected by Hanbo & Kia's bankruptcy, continuous large scale corporates bankruptcy and crisis of foreign exchange. Therefore, financial instability is occured. If portfolio investment fund has been inflow as it is mollified by continuous shortage of foreign exchange and fall of country's credit rating, it is expected to have positive effect for long-term & short-term interest rate from appreciation of won against dollar. Second, results from relation between determination factor of foreign exchange rate and interest rate are followed by next sentences. If surplus of current account and goods account is continued, yield of corporate bond is to be stable. But, margin of surplus is expected to diminish after second quarter 98, and difference between external and domestic interest (after adjusting foreign exchange rate) is to be diminished. And if net inflows of foreign investor's fund (stock and bond) is diminished, it is to have negative effect for yield of corporate bond. According to foreign investor's investment movement of previous years, hedge fund were stayed at least during two years in Mexico. It means that sudden capital outflow is not to be happened at Korea. But if external factors from depreciation of yen and China's renminbi are instable, interest rate is expected to increase from capital's outflows. Third, if it is to decrease instability of foreign exchange rate from increase in surplus of future current account, credit rating's upwardness, stability of yen and renminbi, foreign exchange rate is expected to be stable. It is expected to have continuous stability from short-term interest rate to long-term interest rate in this empirical test.

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Analysis about relation of Won/Dollar Foreign Exchange Rate and Interest Rate of Korea (한국 원/달러환율과 금리의 관계분석)

  • 김종권
    • Proceedings of the Safety Management and Science Conference
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    • 2002.11a
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    • pp.305-319
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    • 2002
  • International capital movement has made progress at global liberalization of finance and foreign exchange, international monetary norm changing into floating exchange rate system, easiness of collection of information and trade at improvement of information communication technology from early of 1970's. Results of empirical test for relation between foreign exchange rate or various determination factors of foreign exchange rate and interest rate are followed by next sentences. First, according to relation between foreign exchange rate and interest rate, correlation for each of variables after OECD entrance is increased. But, long-term &short-term interest rate is affected by Hanbo & Kia's bankruptcy, continuous large scale coporates bankruptcy and crisis of foreign exchange. Therefore, financial instability is occured. If portfolio investment fund has been inflow as it is mollified by continuous shortage of foreign exchange and fall of country's credit rating, it is expected to have positive effect for long-term & short-term interest rate from appreciation of won against dollar. Second, results from relation between determination factor of foreign exchange rate and interest rate are followed by next sentences. If surplus of current account and goods account is continued, yield of corporate bond is to be stable. But, margin of surplus is expected to diminish after second quarter 98, and difference between external and domestic interest (after adjusting foreign exchange rate) is to be diminished. And if net inflows of foreign investor's fund (stock and bond) is diminished, it is to have negative effect for yield of corporate bond. According to foreign investor's investment movement of previous years, hedge md were stayed at least during two years in Mexico. It means that sudden capital outflow is not to be happened at Korea. But if external factors from depreciation of yen and China's renminbi are instable, interest rate is expected to increase from capital's outflows. Third, if it is to decrease instability of foreign exchange rate from increase in surplus of future current account, credit rating's upwardness, stability of yen and renminbi, foreign exchange rate is expected to be stable. It is expected to have continuous stability from short-term interest rate to long-term interest rate in this empirical test.

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The Changes of the Heart Rate, Hand Function, and Health related Quality of Life of the People with Intellectual Disability through the Increase of the Auditory Stimulation (청각자극 증가에 따른 지적장애인의 심박수와 손 기능, 건강관련 삶의 질의 변화)

  • Son, Sung-Min;Kang, Jin-Ho;Bak, Ah-Ream
    • Journal of Korea Entertainment Industry Association
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    • v.14 no.5
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    • pp.217-227
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    • 2020
  • The purpose of the study is to analyze the changes of the heart rate, hand function, and health related quality of life of the people with intellectual disability through the increase of the auditory stimulation. The subjects were 16 people with intellectual disability. The increase of the auditory stimulation was modulated through the music sound and the intensity was consisted of 60dB, 65dB and 70dB. The wist heart rate and blood pressure monitor was used to measure the heart rate during the application of the auditory stimulation increase. The hand function of right and left hand was measured by the Purdue pegboard. Health related of quality of life was measured by the short form-8 health survey. As the results, the increase of the heart rate was showed by the increase of the auditory stimulation and the decrease of the hand function and health related quality of life was showed. For these, the increase of the auditory stimulation acts as a psychological distress, thereby the increase of the heart rate and the reduction of the hand function and health relate quality of life showed. Thus, to decrease of the heart rate and increase the hand function and the health related quality of life of the people with intellectual disability, the intensity of the auditory stimulation should be considered in the environmental stimulation.

Analysis of Factors Affecting on the Freight Rate of Container Carriers (컨테이너 운임에 미치는 영향요인 분석)

  • Ahn, Young-Gyun;Ko, Byoung-Wook
    • Korea Trade Review
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    • v.43 no.5
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    • pp.159-177
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    • 2018
  • The container shipping sector is an important international logistics operation that connects open economies. Freight rates rapidly change as the market fluctuates, and staff related to the shipping market are interested in factors that determine freight rates in the container market. This study uses the Vector Error Correction Model(VECM) to estimate the impact of factors affecting container freight rates. This study uses data published by Clarksons. The analysis results show a 4.2% increase in freight rates when world container traffic increases at 1.0%, a 4.0% decrease in freight rates when volume of container carriers increases by 1.0%, a 0.07% increase in freight rates when bunker price increases by 1.0%, and a 0.04% increase in freight rates accompanying 1.0% increase in libor interests rates. In addition, if the current freight rate is 1.0% higher than the long-term equilibrium rate, the freight rate will be reduced by 3.2% in the subsequent term. In addition, if the current freight rate is 1.0% lower than the long-term equilibrium rate, the freight rate will decrease by 0.12% in the following term. However, the adjusting power in a period of recession is not statistically significant which means that the pressure of freight rate increase in this case is neglectable. This research is expected to contribute to the utilization of scientific methods in forecasting container freight rates.

Evaluation on Early-maturing Korean Japonica Cultivars for High-temperature Tolerance during Grain Filling Stage (국내 육성 조생종 벼 품종들에 대한 등숙기 고온내성 평가)

  • Cho, Seong-Woo;Jeung, Ji-Ung;Kang, Kyung-Ho;Kim, Hyun-Soon;Kim, Bo-Kyeong
    • KOREAN JOURNAL OF CROP SCIENCE
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    • v.60 no.2
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    • pp.146-152
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    • 2015
  • Early-maturing Korean Japonica cultivars and Jungmo1024 were used as plant materials to evaluate hightemperature tolerance during grain filling stage. National Institute of Crop Science (NICS) in Korea developed Jungmo1024, a mutant line from Namil (wild type) treated by using sodium azide (SA) as mutagen. To evaluate high-temperature tolerance, all cultivars were exposed to high-temperature (day $31.5{\pm}2.5^{\circ}C$/ night $27.5{\pm}1.3^{\circ}C$) and ordinary temperature (day $27.5{\pm}1.8^{\circ}C$/ night $24.7{\pm}1.6^{\circ}C$) during grain filling stage. In these conditions, we performed compared evaluation of grain shape such as length and width and grain quality by using a 1625 Cervitec grain inspector. High-temperature during grain filling stage caused decrease of grain shape. In grain shape such as length and width, the decrease rate of width (average 6.3%) was higher than the decrease rate of length (average 1.3%). Hence, high-temperature affected width of grain than length of grain. In addition, high-temperature showed a decided difference in rate of head rice between ordinary temperature (average 76.3%) and high-temperature (average 13.3%).As a result, Taebong, Ungwang, Manan, and Jungmo1024 seemed relatively a decent high-temperature tolerance than other cultivars. Especially, Jungmo1024 seemed remarkable rate of head rice (average $34.4{\pm}6.2%$) than other cultivars under high-temperature. It is considered that a genetic trait of Jungmo1024 can be useful to improve breeding for high-temperature tolerance.

AN EXPERIMENTAL STUDY OF MANDIBULAR FRACTURE WOUND HEALING IN THE CALCIUM DEFICIENT RAT (저칼슘식이가 백서의 하악골 골절치유에 미치는 영향에 관한 실험적 연구)

  • LEE Sang-Hoon;HWANG Eui-Hwan;LEE Sang-Rae
    • Journal of Korean Academy of Oral and Maxillofacial Radiology
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    • v.27 no.1
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    • pp.123-140
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    • 1997
  • The purpose of this study was to investigate effects of osteoporosis on fracture wound healing in the calcium deficient rat. To research the experiment some ten-week old Wistar strain rats with approximately 300 gms weight were selected. Then, the rats were divided into two groups: Normal diet group(rats given a normal diet before and after bone fracture) and Low calcium diet group(rats given a low calcium diet before and after bone fracture). Both groups had been provided with each diet for three weeks. When the rats became thirteen weeks old, the mandibular angle of rats in both groups was artificially fractured for test. The healing of fracture wounds was reviewed by using soft x-ray radiography and /sup 99m/Tc-MDP bone scan and also histopathologic examination. The obtained results were as follows : 1. The radiolucency of the fracture site for the Normal diet group started to decrease from the 14th day since the experiment was made, while the Low calcium diet group began decrease in the radiolucency from the 21st day of the experiment. The radiolucency for the Normal diet group disappeared at the 42nd day, but one for the Low calcium diet group disappeared at the 56th day of the experiment. 2. The highest uptake rate of /sup 99m/Tc-MDP stood at the 14th day of the experiment in the Normal diet group and the Low calcium diet group's maximum rate was recorded at the 21st day of the experiment. These both groups were gradually experiencing decrease in the uptake rate as the experiment time was going on. However, the uptake rate in the Low calcium diet group was lower than one in the Normal diet group. 3. For the Normal diet group, the newly formed trabeculae, which were similar to one of the surroundung bone, were seen at the 42nd day of the experiment. On the other hand, the Low calcium diet group showed at the 56th day of the experiment that the osteoporotic findings looked weak, irregular trabeculae, and also large bone marrow space were observed clearly. As a result of the above experiment, it is said that the healing of the fracture can be completed for both groups, the Normal diet group and the Low calcium diet group. However, the amount of the newly formed bone wound in the Low calcium diet group is rather decreased compared to one in the Normal diet group and at the same time the healing of the fracture is delayed in the Low calcium diet group. Consequently, for the successful healing of fracture in osteoporosis, it is considered that the management of the etiologic factors of osteoporosis must be preceded. The more study of calcium metabolism and functions of osteoblast and osteoclast needs to proceed on.

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