• Title/Summary/Keyword: DeLong

Search Result 503, Processing Time 0.03 seconds

Characterization of Equine Milk and Cheese Making

  • Chang, O.K.;Humbert, G.;Gaillard, J.L.;Lee, B.O.
    • Food Science of Animal Resources
    • /
    • v.26 no.3
    • /
    • pp.368-374
    • /
    • 2006
  • We have studied on characterization and cheese making like mineral contents, protein composition and coagulation pattern on equine milk. At first, for contents of mineral on equine milk, It was lower in equine than bovine milk Contents of Na, Mg, P, Ca and K the major minerals, were indicated as 18.3 mg, 0.4 mg, 33.3 mg, 80.9 mg and 134.9 mg respectively by 100 g. In the distribution of nitrogen, the ratio NPN to Nt was indicated as 9.8% while that of bovine milk was 7%. And In NCN, its percentage was indicated as 45.6% shelving that Equine casein was lower than bovine. From these results, equine milk could not be applicable to cheese production since there are no coagulable nitrogen fraction such as ${\kappa}$-casein, as there aye with bovine milk. Equine milk will be more acceptable if we accept that the phylogenic affinity is near to human. It is the same as equine from the view points that monogastric, which did not contain ruminant's casein. For the rennet coagulation, equine milk was different than bovine milk. Equine milk did not coagulated by rennet after the addition of $Ca^{2+}$. But when bovine ${\kappa}$-casein was added in the presece of rennet, and $Ca^{2+}$ to equine milk, coagulation occurred. Such phenomenon was also observed by the use SEM. Verification of ${\kappa}$-casein by SDS-PACE did not existed in equine milk. The Casein of equine milk(54.4%) is similar to human milk in that casein/whey is about 1. For equine milt this can be explained because distance between casein and Ca is great, casein being lower, which result in reaction of casein with $Ca^{2+}$ because it could not activated which lasting time of coagulation is too long.

De Novo Drug Design Using Self-Attention Based Variational Autoencoder (Self-Attention 기반의 변분 오토인코더를 활용한 신약 디자인)

  • Piao, Shengmin;Choi, Jonghwan;Seo, Sangmin;Kim, Kyeonghun;Park, Sanghyun
    • KIPS Transactions on Software and Data Engineering
    • /
    • v.11 no.1
    • /
    • pp.11-18
    • /
    • 2022
  • De novo drug design is the process of developing new drugs that can interact with biological targets such as protein receptors. Traditional process of de novo drug design consists of drug candidate discovery and drug development, but it requires a long time of more than 10 years to develop a new drug. Deep learning-based methods are being studied to shorten this period and efficiently find chemical compounds for new drug candidates. Many existing deep learning-based drug design models utilize recurrent neural networks to generate a chemical entity represented by SMILES strings, but due to the disadvantages of the recurrent networks, such as slow training speed and poor understanding of complex molecular formula rules, there is room for improvement. To overcome these shortcomings, we propose a deep learning model for SMILES string generation using variational autoencoders with self-attention mechanism. Our proposed model decreased the training time by 1/26 compared to the latest drug design model, as well as generated valid SMILES more effectively.

A Determining System for the Category of Need in Long-Term Care Insurance System using Decision Tree Model (의사결정나무기법을 이용한 노인장기요양보험 등급결정모형 개발)

  • Han, Eun-Jeong;Kwak, Min-Jeong;Kan, Im-Oak
    • The Korean Journal of Applied Statistics
    • /
    • v.24 no.1
    • /
    • pp.145-159
    • /
    • 2011
  • National long-term care insurance started in July, 2008. We try to make up for weak points and develop a long-term care insurance system. Especially, it is important to upgrade the rating model of the category of need for long-term care continually. We improve the rating model using the data after enforcement of the system to reflect the rapidly changing long-term care marketplace. A decision tree model was adpoted to upgrade the rating model that makes it easy to compare with the current system. This model is based on the first assumption that, a person with worse functional conditions needs more long-term care services than others. Second, the volume of long-term care services are de ned as a service time. This study was conducted to reflect the changing circumstances. Rating models have to be continually improved to reflect changing circumstances, like the infrastructure of the system or the characteristics of the insurance beneficiary.

Tip and taper compatibility of accessory gutta-percha points with rotary and reciprocating instruments

  • Julia Niero Zanatta Streck; Sabrina Arcaro;Renan Antonio Ceretta;Eduardo Antunes Bortoluzzi;Lucas da Fonseca Roberti Garcia;Josiane de Almeida ;Patricia Maria Poli Kopper ;Anarela Vassen Bernardi
    • Restorative Dentistry and Endodontics
    • /
    • v.48 no.3
    • /
    • pp.22.1-22.8
    • /
    • 2023
  • Objectives: This study was conducted to evaluate and compare the tip and taper compatibility of accessory gutta-percha points (AGPs) with various rotary and reciprocating instruments. Materials and Methods: Using a profile analyzer, tip and taper measurements were taken of 10 AGPs of each of the 14 models available from Odous de Deus and the 4 models available from Dentsply-Maillefer. Diameter measurements were taken at 1-mm intervals, from 3 mm from the tip (D3) to 16 mm. Results: Based on the mean values obtained, 3-dimensional (3D) models of the AGPs were drawn in Autodesk Fusion 360 and superimposed on 3D models of each instrument selected (Mtwo, Reciproc, RaCe, K3, and ProDesign Logic) to determine the compatibility between the instrument and the AGP. Data corresponding to the tips and tapers of the various AGPs, as well as the tip and taper differences between the AGPs and the instruments, were analyzed using descriptive statistics. The tapers of the AGPs were subject to the American National Standards Institute/American Dental Association No. 57 standard. The Odous de Deus extra-long medium and extra-long extra-medium AGPs were shown to be compatible with Mtwo, K3, and ProDesign Logic instruments with taper 0.06 and tip sizes 25 and 30, while the Dentsply fine and fine medium cones were compatible with Mtwo, RaCe, and K3 instruments with conicity of 0.04 and tip sizes 35 and 40. Conclusions: Both the Odous de Deus and Dentsply commercial brands included 2 AGP models with tip (D3) and taper compatibility with Mtwo, RaCe, K3, and/or Prodesign Logic instruments.

Medical treatment of dissecting aortic aneurysm: report of a case (박리성 대동맥류의 보존적 치료 1례 보)

  • 김병열
    • Journal of Chest Surgery
    • /
    • v.17 no.4
    • /
    • pp.687-690
    • /
    • 1984
  • Aortic dissection, a condition characterized by hemorrhage into the media and variable extension along the length of the aorta, has long been recognized as a catastrophic Cardiovascular event. Recent developments in diagnostic and therapeutic skills have improved the prognosis considerably, but there is still controversy as to how cases should be managed. We experienced a case of dissecting aortic aneurysm [DeBakey Type III ], which were managed using intensive medical treatment. The period of follow up was about 11 years. At last, patient was died by progression of dissection into proximal aorta and resulted in aortic insufficiency and congestive heart failure.

  • PDF

A Study on the Development of the Portable Intelligent QT Analyzer (휴대용 Intelligent QT 분석기의 개발에 관한 연구)

  • 이경중;민혜정
    • Journal of Biomedical Engineering Research
    • /
    • v.11 no.1
    • /
    • pp.57-64
    • /
    • 1990
  • This study describes the design of the portable intelligent QT analyzer which can record and analyze the ambulatory ECG data. System hardware is consisted of the one chip microcomputer(80C31) , A/D, ROM, RAM, LCD display and preamplifier. ECG data were processed by the differentiator and the digital filter. The de- tection of the parameters-QT, QTP and RR interval-was accomplished by the software algorithm using the slope and the amplitude of the processed data. Using this system, the trends of the parameters obtained during the long term could be observed.

  • PDF

Characteristics of the closed microhollow cathode discharge for DC Plasma Display Panels

  • Park, Hae-Il;Noh, Joo-Hyon;Ryu, Byung-Gil;Baik, Hong-Koo
    • 한국정보디스플레이학회:학술대회논문집
    • /
    • 2000.01a
    • /
    • pp.105-106
    • /
    • 2000
  • The positive slope of the current-voltage characteristic at pressure up to 850 torr was obtained using the closed microhollow cathode without the individual and/or distributed ballast. This indicates that the stable parallel operation of the discharge was also achieved using the closed microhollow cathode. The parallel operation makes it possible to manufacture de plasma displays with high pressure, small discharge current, and long lifetime.

  • PDF

Development of Low Anchoring Strength Liquid Crystal Mixtures for Bistable Nematic Displays

  • Stoenescu, D.;Lamarque-Forget, S.;Joly, S.;Dubois, J.C.;Martinot-Lagarde, Ph.;Dozov, I.
    • 한국정보디스플레이학회:학술대회논문집
    • /
    • 2005.07a
    • /
    • pp.97-100
    • /
    • 2005
  • The recent Bistable Nematic ($BiNem{(R)}$) LCD technology presents long term bistability, high level passive matrix multiplexing and high optical quality. The BiNem device, based on anchoring breaking, needs specific low anchoring strength materials - alignment layers and liquid crystal mixtures. We present here our approach to develop nematic mixtures with wide enough temperature range and low zenithal anchoring energy.

  • PDF

Generation of Long Water Waves by Moving Submerged Bodies (수중물체의 운동에 의한 장수파의 생성)

  • Seung-Joon,Lee
    • Bulletin of the Society of Naval Architects of Korea
    • /
    • v.24 no.2
    • /
    • pp.55-61
    • /
    • 1987
  • The wave system due to a moving submerged body is investigated both theoretically and numerically. Boussinesq equation, which is derived under the assumption that the effects of nonlinearity and wave dispersion are of the same order, is generalized to take the forcing agency into account. Furthermore, under the more restrive assumption that the disturbance is of higher order, inhomogeneous Korteweg-de Vries equation is derived. These equations are solved numerically to obtain the generated wave system and the wave-making resistance. These results are compared with those given by the linear theory.

  • PDF