• 한국전자통신학회논문지
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• 제11권2호
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• pp.237-244
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• 2016

보행자가 생활환경에서 겪을 수 있는 위험을 인지하기 위하여 감지하여야 하는 목표를 두 가지로 고려할 수 있다. 위험을 감지하기 위하여 보행자의 상태와 보행 환경 요인을 함께 인지하는 것이다. 생활 안전을 위하여 사물인터넷 기술이 좋은 기여를 할 수 있다. 본 연구는 보행자의 상태와 주변 환경 요인들에 대한 데이터 융합 처리를 이용하여 위험을 인지하는 방안을 제안하였다. 3축 가속도 센서를 이용하여 보행자의 걸음을 인식하고 이를 개인의 상태 추정에 활용하였으며, 조도 센서로부터의 측정값으로 보행환경을 추정하였다. 위험 요인들을 평가하고 융합 처리함으로써 보행자의 위험도를 산출하였다.

• 대한의생명과학회지
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• 제19권3호
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• pp.173-179
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• 2013

Since the identification and characterization of toll-like receptors (TLR) in Drosophila, numerous scientific studies have examined the role of TLRs in host innate immunity. Recent studies have suggested a convergence of the nuclear factor kappa B (NF-${\kappa}B$) signaling and cytokine production regulated by the cytosolic elicitor known as NLRs (nucleotide-binding domain and leucine-rich repeat containing domain receptors) as a key modulator in inflammatory diseases. Among the NLRs, NOD1 and NOD2 have been intensively investigated for its role in inflammatory bowel disease (IBD). On the other hand, NLRs such as NLRP3, NLRP1, and NLRC4 (also known as IPAF) have been identified to form the inflammasome to activate downstream signaling molecules in response to pathogenic microbes. There is evidence to suggest that substantial crosstalk exists for the TLR and NLR signaling pathway in response to pathogen associated molecular pattern (PAMP). However, the substrate and the mechanistic role of NLRs are largely unknown in innate immune response. Understanding the signaling mechanisms by which NLRs recognize PAMP and other danger signals will shed light on elucidating the pathogenesis of various human inflammatory diseases such as IBD.

• BMB Reports
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• 제51권5호
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• pp.219-224
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• 2018

Necroptosis is an emerging form of programmed cell death occurring via active and well-regulated necrosis, distinct from apoptosis morphologically, and biochemically. Necroptosis is mainly unmasked when apoptosis is compromised in response to tumor necrosis factor alpha. Unlike apoptotic cells, which are cleared by macrophages or neighboring cells, necrotic cells release danger signals, triggering inflammation, and exacerbating tissue damage. Evidence increasingly suggests that programmed necrosis is not only associated with pathophysiology of disease, but also induces innate immune response to viral infection. Therefore, necroptotic cell death plays both physiological and pathological roles. Physiologically, necroptosis induce an innate immune response as well as premature assembly of viral particles in cells infected with virus that abrogates host apoptotic machinery. On the other hand, necroptosis per se is detrimental, causing various diseases such as sepsis, neurodegenerative diseases and ischemic reperfusion injury. This review discusses the signaling pathways leading to necroptosis, associated necroptotic proteins with target-specific inhibitors and diseases involved. Several studies currently focus on protective approaches to inhibiting necroptotic cell death. In cancer biology, however, anticancer drug resistance severely hampers the efficacy of chemotherapy based on apoptosis. Pharmacological switch of cell death finds therapeutic application in drug- resistant cancers. Therefore, the possible clinical role of necroptosis in cancer control will be discussed in brief.

• 의료법학
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• 제13권2호
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• pp.263-284
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• 2012

Medical Act. article 2 (3) stipulates that "a korean medicine doctor is in charge of providing korean medical practices and korean medical health guidance". But, without a definition article about korean medical practice, the legal concept of it is defined by supreme court cases according to specific legal trials. To establish the concept of korean medical practice, it must be included that the common parts of practice of medicine involving "the purpose of practice", "the subject of practice", "the object of practice" and "other dangers", as well as the special parts of conceptual elements of korean medical practice involving "korean medicine principle" and "differentiation" and also "manufacturing of korean medicine". Accordingly, the definition of korean medical practice is defined as examining, diagnosing, differentiating, prescribing, manufacturing of korean medicine, treating, korean medical care guiding so as to treat diseases and to promote and to maintain health, based on korean medicine as traditionally handed down from the nation's ancestors and korean medicine principle which is scientifically developed and applied and also includes a practice that will cause physiological danger to human body and/or bring harm to public health and sanitation if it is not perfomed by korean medicine doctor.

• 한국기계가공학회지
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• 제3권3호
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• pp.79-85
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• 2004

The lightness of components required in automobile and machinery industry is requiring high strength of components. In particular, fatigue failure phenomena, which happen in metal, bring on danger in human life and property. Therefore, antifatigue failure technology takes an important part of current industries. Currently, the shot peening is used for removing the defects from the surface of steel and improving the fatigue strength on surface. Therefore, in this paper the effect of compressive residual stress of spring steel(JISG SUP-9)by shot peening on fatigue crack growth characteristics in stress ratio(R=0 1, R=0 3, R=0 6)was investigated considering fracture mechanics. By using the methods mentioned above, I arrived at the following conclusions: (1) The fatigue crack growth rate(da/dN) of the shot peening material was lower than the unpeening material And in stage I, ${\Delta}K_{th}$, the threshold stress intensity factor, of the shot peening material is high in critical parts unlike the unpeening material. (2) Fatigue life shows more Improvement in the shot peening material than in the unpeening material. And compressive residual stress of surface on the shot peening processed operate the resistance of fatigue crack propagation.

• 한국의류학회지
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• 제29권8호
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• pp.1049-1056
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• 2005

The purpose of the study was to investigate adolescents' attitudes toward clothing advertisements and, to examine how much the influence of clothing ads on their clothing purchase depends on their clothing involvements. This research was based on a survey method using questionnaires. The subjects for the research were 508 middle and high school students in the area of Daegu City and Gyungbuk Province. Such methods as factor analysis, correlations, ANOVA, T-test and Scheff's test were used to analyze the collected data. The results of this study can be summarized as follows: 1. Adolescents' clothing involvements showed three dimensions such as interest and symbolism, fashion and danger perception. 2. They showed three different attitudes toward clothing ads: positive, negative, and reliant. 3. The degree of the influence of clothing ads on adolescents' clothing purchase was great in the order of media ads, shop ads, discount ads and brand ads. 4. The more interested they were in clothing, the more likely they were to purchase their clothing on their will and the more positive and reliant on clothing ads they were, which they recognized as useful information.

• 한국사회복지학
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• 제45권
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• pp.185-219
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• 2001

The purpose of this study is to explore the concept of social exclusion and underclass and to find out their implication for the poverty policy in Korea. Social exclusion as a concept, on the other hand, offers a broader perspective in addressing multi-dimensional disadvantage, especially in relation to social policy. The term underclass offers a convenient metaphor for use in commentaries on inner city crises because it evokes three widely shared perceptions: novelty, complexity, and danger. Conditions within inner cities are unprecedented; they cannot be reduced to a single factor; and they menace the rest of us. Open debate on the underclass accelerated in 1977 when Time magazine announced the emergence of a menacing underclass in America's inner cities. Drugs, crime, teenage pregnancy, and high unemployment, not poverty, defined the 'underclass,' most of whose members were young and minorities. With the publication in 1982 of Ken Auletta's Underclass, the word secured it dominance in the vocabulary of inner-city pathology. As implications for Korean poverty policy of the concept of social exclusion and underclass, the establishment of multi-dimensional concept of poverty, development of multi-dimensional approach of social work, improvement of National Basic Life Guarantee System, research on employment policy in social welfare field, and research on housing policy for the poor were suggested.

• 한국한의학연구원논문집
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• 제15권3호
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• pp.19-28
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• 2009

Objectives : The lawsuits associated with medical practice in Korean medicine are increasing gradually. However, the clear definition for medical practice in Korean medicine has not been existed in Korean law. Only we may understand the concept regulated by judicial precedents of the court of justice or the authoritative interpretation by the government. Methods : For study, a database was established for medical lawsuits involving Korean medicine(1968~2009, n=130). Results : According to court rulings, the medical practice in Korean medicine is an act to diagnose a person's illness, prescribe and treat to cure based on traditional Korean medicine, to be understood as a medical care, to have some factor to create or increase danger for the preservation of health or hygiene, and to be practiced by medical specialists based on their professional knowledge. Conclusions : But, such definition is not proper and exceedingly vague. Besides medical circumstances Koreans Medicine are changing, and new precedent to the definition of the practice of medicine is establishing. Therefore the meaning and scope of the medical practice in Korean medicine should be modified and amended, reflecting these conditions.

• 소프트웨어공학소사이어티 논문지
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• 제25권1호
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• pp.19-28
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• 2012

기존 인터넷 웹 사이트에서는 개인 식별 도구로 주민등록번호를 사용해 왔다. 그러나 인터넷에서의 주민 등록번호 사용은 개인정보 유출 위험을 증가시키는 주 요인이 되고 있다. 현재 정부에서는 인터넷에서의 주민등록번호 수집과 개인정보 유출 최소화를 위해 i-PIN 서비스를 권장하고 있다. i-PIN의 원래 사용 목적은 인터넷 웹 사이트에서 주민등록번호를 사용하지 않고 i-PIN 13자리 가상번호로 개인을 식별하여 사용된다. 최근에는 i-PIN을 인증서 형태로 사용하는 사례가 늘고 있다. 본 연구에서는 i-PIN을 인증서 형태로 사용하는 소프트웨어 서비스 방법론과 기존 i-PIN 서비스와는 다른 형태의 i-PIN 본인인증서비스 적용 사례를 알아보고자 한다.

• 한국측량학회지
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• 제40권3호
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• pp.195-206
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• 2022

The primary purpose of this study was to analyze assessment factors by identifying and prioritizing live fire shooting area requirements using the AHP (Analytic Hierarchy Process) technique. Derived assessment factors for candidate sites were divided into six categories. Of these, four categories (base-to-range distance, weapon danger area, range terrain, and size) were in the realm of physical geography while the remaining two (land use and proximity to habitation) fell under the general heading of human geography. A case study was also conducted to select several alternative firing ranges using derived factors. The optimal location was analyzed by evaluating the candidate site using each assessment factor. As a result, it was found that assessment factors applying to GIS (Geographic Information System) were able to effectively analyze a suitable location for relocation of the focal training facility, taking into consideration public-safety issues, training requirements, and residents' past and likely future complaints. Through this process, it can prevent the waste of time and effort in determining an optimal location for a live fire shooing range.