• 대한물리치료과학회지
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• 제8권2호
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• pp.989-995
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• 2001

The purpose of this paper was to enable patients, who suffer from muscle damage. to return to their normal activities as soon as possible. With this in mind. this experiment was carried out to make an analysis of a variety of ingredients subjected to changes when muscle damage or muscle soreness was treated with aceclofenac, NSAID, and to find out what effect the anti-inflammation produced in relation to such symptoms. It made use of male rats (Sprague-Dawely) as subjects. It carried out two kinds of experiments: one was a preliminary experiment from March 15, 2001 to March 20, 2001 and the other was a main experiment from March 30, 2001 to April 15, 2001. Each group was composed of five rats. In case of DOMS. it worked with eight male adults from April 20. 2001 to April 30, 2001. It have come up with the following conclusions: 1. The leucocytes and erythrocytes of the experiment group were decreasing with the lapse of time in comparison with those of the contrast group. And a decrease in the number of hemoglobin had remarkably statistic significance (P<0.05). 2. Neutrophil, Lymphocyte and Monocyte decreased in 36, 24, 12 and 24 hours, respectively, which means that they had a significant difference(P<0.05). 3. CPK and LDH were reduced remarkably through the whole time slot in comparison with the contrast group, and had statistic significance(P<0.05). The findings above show that anti-inflammations cure bruises or damage or myalgia in a shorter period of time than the normal recovery of other treatment.

• Tribology and Lubricants
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• 제31권2호
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• pp.69-77
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• 2015

Recently, there have been reports of severe symptoms of wear in bearings due to foreign substances mixed in lubricants. Therefore, studying the effects of foreign substances (such as combustion products and metallic debris) on the wear characteristics of journal bearings and proposing appropriate management standards for lubricant cleanliness have become necessary. Studies on the effect of particle size and concentration of foreign substances on surface damage have actively progressed in the recent times. These studies indicate the possibility of foreign substances causing direct wear of bearing surfaces. However, experiments conducted until now involve only basic tests such as the Pin-on-Disk test instead of those involving real bearing systems. This study experimentally examines the damage to the surface of a journal bearing due to foreign substances (combustion products and alumina) mixed with the lubricant, as well as the effect of the type and size of particles on its wear characteristics. The study uses an experimental journal bearing similar to a real bearing system for conducting the lubrication test. Hydrodynamic Lubrication (HL) numerical analysis, experiment results, and film parameters are used for calculating the operating conditions required for achieving the desired film thickness, and the results of the analysis are modified for considering the surface roughness. The run-time of the experiment is 10 min including the stabilization process. The experiment results show that alumina particles larger than the minimum film thickness cause significant surface damage.

• Maxillofacial Plastic and Reconstructive Surgery
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• 제36권6호
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• pp.273-279
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• 2014

Purpose: This study assessed the association between eye symptoms (enophthalmos or diplopia) and site of damage, volume, deviated inferior rectus muscle (IRM) and type of fracture with computed tomography (CT). The intent is to anticipate the prognosis of orbital trauma at initial diagnosis. Methods: Forty-five patients were diagnosed with fractures of the inferior wall of one orbit. Fracture area, volume of displaced tissue, deviated IRM, and type of fracture were evaluated from coronal CT by one investigator. The association of those variables with the occurrence of eye symptoms (diplopia and enophthalmos) was assessed. Results: Of 45 patients, 27 were symptom-free (Group A) and 18 had symptoms (Group B) of enophthalmos and/or diplopia. In Group B, 12 had diplopia, one was enophthalmos, and five had both. By CT measurement, group A mean area was $192.6mm^2$ and the mean volume was $673.2mm^3$. Group B area was $316.2mm^2$ and volume was $1,710.6mm^3$. The volume was more influential on symptom occurrence. Each patient was categorized into four grades depending on the location of IRM. Symptom occurrence and higher grade were associated. Twenty-six patients had trap-door fracture (one side, attached to the fracture), and 19 had punched-out fracture (both sides detached). The punched-out fracture was more strongly associated with symptoms and had statistically significantly higher area and volume. Conclusion: In orbital trauma, measurement of fracture area and volume, evaluation of the deviated IRM and classification of the fracture type by coronal CT can effectively predict prognosis and surgical indication.

• 혜화의학회지
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• 제14권2호
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• pp.113-126
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• 2005

Atopic dermatitis(AD) is a chronic disease that affects the skin. "Atopic" refers to a group of diseases where there is often an inherited tendency to develop other allergic conditions, such as asthma and hay fever. In AD, symptoms vary from person to person. The most common symptoms are dry, itchy skin and rashes on the face, inside the elbows and behind the knees, and on the hands and feet. Although AD may occur at any age, it most often begins in infancy and childhood. The cause of AD is not known, but the disease seems to result from a combination of hereditary and environmental factors along with malfunction of the body's immune system. In contrast to that, the results from literatual study in oriental medicine are as follows; 1. The causes of AD are considered to be Mosusigisadok(母受時氣毒), Waegampoongsubyeol(外感風濕熱), Guasiksinlayeolmul(過食辛辣熱物), Ohbokonje(誤服溫劑). 2. The symptoms are fever, flushed face, red eyes, oliguria, constipation and itching. 3. Chungyeolhaedok(淸熱解毒) would be the basic method of treatment, and it divides into two categories; Subhyung(濕型) and Gunhyung(乾型). In Subhyung(濕型), AD is treated by Josub(燥濕), Chungyeol(淸熱) and Jiyang(止痒) whereas Chungyeol(淸熱), Jiyang(止痒), Jesub(除濕) in Gunhyung(乾型). 4. To prevent further damage and enhance quality of life, it is necessary to keep the temperature and humidity favorable, and healing the skin and keeping it healthy are important. Developing and sticking with a daily skin care routine is critical to preventing flares. Changing the diet and psychological stability may also be helpful to relieve symptoms of AD.

• Annals of Clinical Neurophysiology
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• 제21권1호
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• pp.36-43
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• 2019

Background: Diabetic peripheral polyneuropathy (DPN) is associated with a variety of symptoms. Nerve conduction studies (NCSs) are considered to be the gold standard of nerve damage assessments, but these studies are often dissociated from the subjective symptoms observed in DPN patients. Thus, the aim of the present study was to investigate the correlations between NCS parameters and neuropathic symptoms quantified using the Michigan Neuropathy Screening Instrument (MNSI). Methods: Patients with type 2 diabetes mellitus (T2DM) with or without symptoms of neuropathy were retrospectively enrolled. Demographic data, clinical laboratory data, MNSI score, and NCS results were collected for analysis; DPN was diagnosed based on the MNSI score (${\geq}3.0$) and abnormal NCS results. Pearson's correlation coefficients were used to evaluate the relationships between MNSI score and NCS variables. Results: The final analyses included 198 patients (115 men and 83 women) with a mean age of $62.6{\pm}12.7$ years and a mean duration of diabetes of $12.7{\pm}8.4$ years. The mean MNSI score was 2.8 (range, 0.0-9.0), and 69 patients (34.8%) were diagnosed with DPN. The MNSI score was positively correlated with the median motor nerve latency and negatively correlated with the median motor, ulnar sensory, peroneal, tibial, and sural nerve conduction velocities (NCVs). When the patients were categorized into quartiles according to MNSI score, peroneal nerve conduction velocity was significantly lower in the second MNSI quartile than in the first MNSI quartile (p = 0.001). A multivariate analysis revealed that the peroneal NCV was independently associated with MNSI score after adjusting for age, sex, and glycosylated hemoglobin A1c (HbA1c) levels. Conclusions: The present results indicate that a decrease in peroneal NCV was responsible for early sensory deficits in T2DM patients.

• 한국융합학회논문지
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• 제8권2호
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• pp.235-241
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• 2017

본 연구는 미용전공 대학생들을 중심으로 두피와 모발의 상태를 정확하게 파악하고 그에 따른 관리 습관 및 자각증상을 인식함으로서 두피 모발의 융합관리 형태에 관심을 갖고 관리하도록 하는데 그 목적이 있다. 연구대상자는 전남지역에 거주하는 20대 미용전공 대학생 160명으로 직접 기입방식으로 설문조사를 실시하였다. 연구결과 두피유형은 복합성 두피가 많았으며, 모발의 문제점으로 모발 끝이 갈라지고 가늘어지는 것을 꼽았고 자신이 손상된 모발을 갖고 있다고 인식하고 있었다. 손상의 원인으로는 잦은 염색과 퍼머라고 답하였으며, 손상을 예방하기 위해 손상모발 샴푸를 주로 사용하고 있었다. 두피 모발에 대한 자각증상에서 두피에 관련하여 관심도가 높을수록 자가인식도가 높았으며 나이와 수면시간도 영향을 주는 것으로 나타났다.

• Annals of Clinical Neurophysiology
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• 제4권1호
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• pp.70-73
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• 2002

Acute autonomic neuropathy is a rare disease. Since the first case was reported by Young et.al., in 1969, a number of similar cases have been described, with some variation of the accompanied neurologic deficits. Acute autonomic and sensory neuropathy(AASN) is characterized by the acute onset of autonomic dysfunction and sensory disturbances. A 16-year-old girl experienced high fever($40^{\circ}C$) and erythematous rash on whole trunk and face followed by pain and sensory loss over the whole body, dysphagia, ataxia, urinary retention, and postural hypotension. There was no evidence of limb weakness. The electrophysiologic studies of this patient revealed sensory polyneuropathy and the various autonomic function test showed autonomic dysfunction. The recovery of her autonomic and sensory symptoms is incomplete, three months after the onset of the symptoms. The etiology of the acute autonomic and sensory neuropathy is not known. Most previous authors have suggested the dysautonomia may be an acute immunological damage to peripheral fibers of the autonomic nervous system. We report a case of acute autonomic and sensory neuropathy.

• Toxicological Research
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• 제12권2호
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• pp.203-211
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• 1996

Methanol has been widely used as an industrial solvent and environmental exposure to methanol would be expected to be increasing. In humans, methanol causes metabolic acidosis and damage to ocular system, and can lead to death in severe and untreated case. Clinical symptoms are attributed to accumulation of forrnic acid which is a metabolic product of methanol. In humans and primates, formic acid is accumulated after methanol intake but not in rodents due to the rapid metabolism of methanol. Neverthless, the developmental and reproductive toxicity were reported in rodents. Previous reports showed that perinatal exposure to ethanol produces a variety of damage in human central nervous system by direct neurotoxicity. This suggests that the mechanism of toxic symptoms by methanol in rodents might mimic that of ethanol in human. In the present study I hypothesized that methanol can also induce toxicity in neuronal cells. For the study, primary culture of rat hippocampal neurons and glias were empolyed. Hippocampal cells were prepared from the embryonic day-17 fetuses and maintained up to 7 days. Effect of methanol (10, 100, 500 and 1000 mM) on neurite outgrowth and cell viability was investigated at 0, 18 and 24 hours following methanol treatment. To study the changes in proliferation of glial cells, protein content was measured at 7 days. Neuronal cell viability in culture was not altered during 0-24 hours after methanol treatment. 10 and 100 mM methanol treatment significantly enhanced neurite outgrowth between 18-24 hours. 7-day exposure to 10 or 100 mM methanol significantly increased protein contents but that to 1000 mM methanol decreased in culture. In conclusion, methanol may have a variety of effects on growing and differentiation of neurons and glial cells in hippocampus. Treatment with low concentration of methanol caused that neurite outgrowth was enhanced during 18-24 hours and the numbers of glial cell were increased for 7 days. High concentration of methanol brought about decreased protein contents. At present, the mechanism responsible for the methanol- induced enhancement of neurite outgrowth is not clear. Further studies are required to delineate the mechanism possibly by employing molecular biological techniques.

• 동의생리병리학회지
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• 제33권2호
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• pp.75-81
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• 2019

In order to research the pathological entity of Jueyin disease in ${\ll}Shanghanlun{\gg}$, some sharing concept of three-yin-three-yang used in ${\ll}Neijing{\gg}$ and ${\ll}Shanghanlun{\gg}$ were investigated first, and then the meaning of jueyin and jueyin disease were analyzed. In cold damage disease, time-space factor is important because the pathological change is rapid and the symptoms along path are similar, therefore three-yin-three-yang having complex meaning of time and space can be used as an appropriate pathological concept. So to speak, it is able to be interpreted as various modes like variations of yin-yang, qi-blood, change of pulse condition, theories of opening, closing, pivot or exuberance and debilitation of form and qi manifested in the six districts of the human body following disease process. Jueyin is between front taiyin and rear shaoyin, and it's attribution is inherent in qi stagnation and yin exuberance in relative to the location of flank and liver. Putting together above descriptions, pathological entity of jueyin disease is that the symptoms mingled with cold and stagnant heat competing each other when a subject having qi stagnation in flank with cold in extremities and lower abdomen in particular is seized with cold influenza.

• 한국응용곤충학회지
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• 제51권1호
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• pp.1-7
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• 2012

최근 들어 노지재배 감귤에서 볼록총채벌레에 의해 검은점무늬병 후기 증상 및 녹응애 피해 증상과 매우 유사하게 과정부 주위를 중심으로 검붉게 그을린 증상 또는 조직이 회갈색으로 괴사되어 딱지형태가 되는 증상들이 2007년부터 서귀포시 남원읍 일부지역에 발생하여 큰 피해를 주고 있다. 황색 끈끈이 트랩을 이용하여 7일 마다 발생 밀도를 조사한 결과 2009년의 경우 5월 상순부터 발생하기 시작하여 꾸준히 증가하다 8월 하순에 밀도가 가장 높았으며 2010년과 2011년의 경우 10월 상순에 밀도가 가장 높았다. 2009년의 경우 5월부터 10월 하순까지 최소 7회의 발생 세대를 보였고 통상 7월 경부터 볼록총채벌레가 감귤원에서 우점하여 발생하였다. 과실에서 볼록총채벌레 약충들이 7월부터 발견되어 2009년의 경우 8월 하순부터 9월 중순, 그리고 10월 상순에 피크를 보였고 피해 증상은 9월 중순부터 발생하기 시작하였다. 2011년의 경우 7월 상순에 밀도가 매우 높았으며 이후 9월 하순에 다시 밀도가 증가하였고 피해 증상은 7월 중하순 부터 발생하기 시작하여 10월 하순까지 계속적으로 증가하였다. 피해증상은 과정부를 중심으로 회색빛으로 부스럼같이 코르크화 되거나 초기에 검은색을 띄다가 착색기에 접어들어 과피가 검붉게 변하였다. 감귤에서 볼록총채벌레에 의한 이런 피해 증상을 국내에 처음으로 보고한다.