• Nutrition Research and Practice
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• v.7 no.5
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• pp.373-379
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• 2013

The consumption of fruits and vegetables that have high polyphenol content has been previously associated with a reduced risk for cardiovascular disease. We investigated the effects of onion peel extract on plasma total antioxidant capacity, lipid peroxidation, and leukocyte DNA damage. This study was a randomized, double-blind, placebo-controlled, crossover trial. Healthy female subjects received either onion peel extract or placebo (dextrin) for two weeks, underwent a 1-week washout period, and then received the other treatment for an additional two weeks. After two weeks of onion peel extract supplementation, the total cholesterol level, low-density lipoprotein cholesterol level, and atherogenic index significantly decreased (P < 0.05). No changes were observed in activities of erythrocyte antioxidant enzymes or levels of lipid peroxidation markers following onion peel extract supplementation. Additionally, no significant difference was found in plasma antioxidant vitamin (retinol, tocopherols, carotenoids, and coenzyme Q10) levels or ex vivo $H_2O_2$-provoked oxidative DNA damage after onion peel extract supplementation. The present interventional study provides evidence of the health benefits of onion peel extract and demonstrates its effects in modulating lipid profiles in healthy young Korean women.

• Journal of the Korean Society of Costume
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• v.53 no.7
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• pp.29-36
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• 2003

The purposes of this syudy were to identify the factors of perceived risk, satisfaction, and intention on rental clothing. The subjects were 767 adults residing in Jeonbuk province. The research was made from February 20 to March 19, 2003. Fof data analysis. frequencies, percentages, mean, and standard deviations were calculated. Also, factor analysis and stepwise multiple-regression analysis were done. The results were as follows: 1. Approximately half of the respondents had experiences of rental clothing, and the most frequent items were wedding dress, degree gown, performance dress, and sports wear in descending order. 2. The factors of perceived risk of rental clothing were divided into lost, appropriateness, and damage, and total variance was 62.51%. The perceived risk about damage of rental clothing was the highest, and lost was the lowest. 3. The factors of rental clothing satisfaction were divided into appearances, store status, function, and fitness, and total variance was 59.96%. The satisfaction of function of rental clothing was the highest, and the store status was the lowest. 4. The intention on rental clothing was high in case of higher interest in rental clothing, higher educational level. more experiences in rental clothing, lower perceived risk of damage on the rental clothing, and younger person, and these variables explained 54.00% of the intention on rental clothing.

• Journal of the Earthquake Engineering Society of Korea
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• v.13 no.4
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• pp.57-65
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• 2009

This study is an evaluation of seismic fragility function using the HAZUS program for railway bridge systems, based on the results of previous research on seismic safety factor. First, a fragility function for each of the bridge members was evaluated according to the damage criteria and failure mode. Subsequently, bridge system fragility was evaluated using a fault tree to describe damage status. Finally, a fragility evaluation method for the bridge system was developed, based on the safety factor derived from the previous research.

• Journal of the Korea institute for structural maintenance and inspection
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• v.2 no.4
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• pp.137-147
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• 1998

The neural net application was tried to develop the technique for monitoring the health status of a steel truss bridge which was scaled down to 1/15 of the real bridge for the laboratory experiments. The damage scenarios were chosen as 7 cases. The dynamic behavior, which was changed due to the breakage of the members, of the bridge was investigated by finite element analysis. The bridge consists of single spam, and eight (8) main structural subsystems. The loading vehicle, which weighs as 100 kgf, was operated by the servo-motor controller. The accelerometers were bonded on the surface of 7 cross-beams to measure the dynamic behavior induced by the abnormal structural condition. Artificial neural network technique was used to determine the severity of the damage. At first, the neural net was learnt by the results of finite element analysis, and also, the maximum detection error was 3.65 percents. Another neural net was also learnt, and verified by the experimental results, and in this case, the maximum detection error was 1.05 percents. In future study, neural net is necessary to be learnt and verified by various data from the real bridge.

• The Journal of the Convergence on Culture Technology
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• v.9 no.4
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• pp.593-599
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• 2023

There is risk of derailment due to various factors such as vehicle-track load imbalance in curved parts, so urban railways install and operate derailing prevent guard rails. The angle-type derailing prevent guard rail is composed of various parts including the guard angle. Even if derailment does not occur, various damages occur in the components, so continuous maintenance is required. Through the damage status analysis, the components of the angle-type derailing prevent guard rail with high damage frequency were classified, and conditions for the occurrence of various damages were investigated. In addition, a numerical analysis using a precise 3D numerical model was performed to analyze the cause of the damage analytically. In order to analytically simulate the derailment situation, the static ultimate load condition was applied, and the actual drawing of the angle-type derailing prevent guard rails, rails, and wheels was used for modeling. By analyzing the results of the damage status investigation and finite element analysis, we tried to investigate the damage of the components.

• Journal of the military operations research society of Korea
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• v.30 no.1
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• pp.92-106
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• 2004

This is a case study which establishes effective ammo issue plan and determines ammo support capability by linking various situations about ammo issue with wargame simulation. Ammo function simulation model has been developed for this matter and it has been proven that the model has significant impact on type of round, parking space for magazine, number of workers and capacity of equipment, etc. during establishing ammo issue plan and determining ammo supply capability. Also, ammo support capability varies significantly depending on tactical damage and MOPP status, etc. ASP's tactical situation, such as magazine damage, MOPP status, type of issuing round, parking space for magazine, number of workers and capacity of equipment, can be reflected when preparing an effective wartime ammo working hour issuing plan for supplying ammo to units through studies results, so that the issuing plan can be realistic and actual.

• BMB Reports
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• v.47 no.4
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• pp.209-214
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• 2014

Ultraviolet B (UVB) radiation induces the production of reactive oxygen species (ROS) that promote apoptotic cell death. We showed that cytosolic $NADP^+$-dependent isocitrate dehydrogenase (IDPc) plays an essential role in the control of cellular redox balance and defense against oxidative damage, by supplying NADPH for antioxidant systems. In this study, we demonstrated that knockdown of IDPc expression by RNA interference enhances UVB-induced apoptosis of immortalized human HaCaT keratinocytes. This effect manifested as DNA fragmentation, changes in cellular redox status, mitochondrial dysfunction, and modulation of apoptotic marker expression. Based on our findings, we suggest that attenuation of IDPc expression may protect skin from UVB-mediated damage, by inducing the apoptosis of UV-damaged cells.

• BMB Reports
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• v.44 no.5
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• pp.312-316
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• 2011

1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) and its toxic metabolite 1-methyl-4-phenylpyridium ion (MPP$^+$) have been shown to induce Parkinson's disease-like symptoms as well as neurotoxicity in humans and animal species. Recently, we reported that maintenance of redox balance and cellular defense against oxidative damage are primary functions of the novel antioxidant enzyme cytosolic NADP$^+$-dependent isocitrate dehydrogenase (IDPc). In this study, we examined the role of IDPc in cellular defense against MPP$^+$-induced oxidative injury using PC12 cells transfected with IDPc small interfering RNA (siRNA). Our results demonstrate that MPP$^+$-mediated disruption of cellular redox status, oxidative damage to cells, and apoptotic cell death were significantly enhanced by knockdown of IDPc.

• Proceedings of the Korean Society for Noise and Vibration Engineering Conference
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• 2003.11a
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• pp.21-32
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• 2003

Developments and applications of the structural health monitoring (SHM) systems have become active particularity for long-span bridges in Korea. They are composed of sensors, data acquisition system, data transmission system, information processing, damage assessment, and information management. In this paper, current status of research and application activities on SHM systems for civil infra-structures in Korea are briefly introduced by 4 parts: (1) current status of bridge monitoring systems on existing and newly constructed bridges, (2) research and development activities on smart sensors such as optical fiber sensors and piezo-electric sensors, (3) structural damage detection methods using measured data, and (4) a test road project for pavement design verification and enhancement by the Korea Highway Corporation. Finally the R＆D activities of a new engineering research center entitled Smart Infra-Structure Technology Center at Korea Advanced Institute of Science and Technology are also briefly described.

• Proceedings of the Earthquake Engineering Society of Korea Conference
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• 2006.03a
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• pp.358-365
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• 2006

In this study, fragility curves of continuous buried pipelines subjected to transverse PGD (permanent ground deformation) due to liquefaction are proposed. For the waterworks system, continuos buried pipelines made of ductile iron, poly ethylene, and poly vinyl chloride are analyzed and fragility curves are drawn. Fragility curves are based on the repetitive analyses results and formulated with the dominant factors of behaviour of buried pipeline. With the use of fragility curves, engineers can estimate the status of damage of buried pipeline without overall knowledge of relevant features. Especially, fragility curves proposed in this study will act as a major module of earthquake loss estimation method. Moreover, critical value of magnitude and width of transverse PGD (by which the full damage status of buried pipelines are induced) are estimated. With the use of regression curves of these values, pre evaluation of seismic safety of buried pipelines located within liquefaction hazardous region will be possible.