• Nutrition Research and Practice
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• 제7권5호
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• pp.373-379
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• 2013

The consumption of fruits and vegetables that have high polyphenol content has been previously associated with a reduced risk for cardiovascular disease. We investigated the effects of onion peel extract on plasma total antioxidant capacity, lipid peroxidation, and leukocyte DNA damage. This study was a randomized, double-blind, placebo-controlled, crossover trial. Healthy female subjects received either onion peel extract or placebo (dextrin) for two weeks, underwent a 1-week washout period, and then received the other treatment for an additional two weeks. After two weeks of onion peel extract supplementation, the total cholesterol level, low-density lipoprotein cholesterol level, and atherogenic index significantly decreased (P < 0.05). No changes were observed in activities of erythrocyte antioxidant enzymes or levels of lipid peroxidation markers following onion peel extract supplementation. Additionally, no significant difference was found in plasma antioxidant vitamin (retinol, tocopherols, carotenoids, and coenzyme Q10) levels or ex vivo $H_2O_2$-provoked oxidative DNA damage after onion peel extract supplementation. The present interventional study provides evidence of the health benefits of onion peel extract and demonstrates its effects in modulating lipid profiles in healthy young Korean women.

• 복식
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• 제53권7호
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• pp.29-36
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• 2003

The purposes of this syudy were to identify the factors of perceived risk, satisfaction, and intention on rental clothing. The subjects were 767 adults residing in Jeonbuk province. The research was made from February 20 to March 19, 2003. Fof data analysis. frequencies, percentages, mean, and standard deviations were calculated. Also, factor analysis and stepwise multiple-regression analysis were done. The results were as follows: 1. Approximately half of the respondents had experiences of rental clothing, and the most frequent items were wedding dress, degree gown, performance dress, and sports wear in descending order. 2. The factors of perceived risk of rental clothing were divided into lost, appropriateness, and damage, and total variance was 62.51%. The perceived risk about damage of rental clothing was the highest, and lost was the lowest. 3. The factors of rental clothing satisfaction were divided into appearances, store status, function, and fitness, and total variance was 59.96%. The satisfaction of function of rental clothing was the highest, and the store status was the lowest. 4. The intention on rental clothing was high in case of higher interest in rental clothing, higher educational level. more experiences in rental clothing, lower perceived risk of damage on the rental clothing, and younger person, and these variables explained 54.00% of the intention on rental clothing.

• 한국지진공학회논문집
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• 제13권4호
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• pp.57-65
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• 2009

본 연구에서는 HAZUS와 같은 지진위험도 추정을 위한 입력으로서 교량구조물에 대한 대표 지진취약도 함수를 도출하기 위하여 기존에 수행되었던 안전율 평가 결과를 이용하여 일련의 교량군에 대한 대표 지진취약도 함수를 도출하는 방법을 제안하였다. 지진응답해석 결과를 근거로 하여 제시된 교량 집단의 각 부재별 안전율을 정리하였으며 이 안전율 결과를 이용하여 각 파괴모드별 지진취약도 곡선을 도출하였다. 각 부재별로 평가된 지진취약도 함수를 이용하여 HAZUS의 입력으로 사용할 수 있는 손상단계별 지진취약도 함수를 도출하였다. 부재별 파괴모드를 이용하여 교량전체의 시스템 취약도를 도출하기 위하여 고장수목을 사용하였다. 결과적으로 본 연구에서는 기존의 안전율결과를 이용하여 취약도결과를 도출할 수 있는 방법을 제시하였다.

• 한국구조물진단유지관리공학회 논문집
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• 제2권4호
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• pp.137-147
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• 1998

The neural net application was tried to develop the technique for monitoring the health status of a steel truss bridge which was scaled down to 1/15 of the real bridge for the laboratory experiments. The damage scenarios were chosen as 7 cases. The dynamic behavior, which was changed due to the breakage of the members, of the bridge was investigated by finite element analysis. The bridge consists of single spam, and eight (8) main structural subsystems. The loading vehicle, which weighs as 100 kgf, was operated by the servo-motor controller. The accelerometers were bonded on the surface of 7 cross-beams to measure the dynamic behavior induced by the abnormal structural condition. Artificial neural network technique was used to determine the severity of the damage. At first, the neural net was learnt by the results of finite element analysis, and also, the maximum detection error was 3.65 percents. Another neural net was also learnt, and verified by the experimental results, and in this case, the maximum detection error was 1.05 percents. In future study, neural net is necessary to be learnt and verified by various data from the real bridge.

• 문화기술의 융합
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• 제9권4호
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• pp.593-599
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• 2023

곡선부에는 차량-궤도의 하중불균형 등 다양한 요인에 의한 탈선의 위험이 내재 되어있어 도시철도에서는 탈선방지 가드레일을 설치, 운영하고 있다. 앵글형 탈선방지 가드레일은 가드앵글을 포함한 다양한 부품으로 구성되어 탈선을 방지하는 기능을 수행하는데 탈선이 발생하지 않더라도 구성품에서 다양한 손상이 발생하고 있어 지속적인 유지관리가 필요하다. 손상현황을 조사하여 손상 빈도가 높은 앵글형 탈선방지 가드레일의 구성품을 분류하였으며, 다양한 손상의 발생 조건 등을 조사하였다. 또한 손상원인을 공학적으로 분석하고자 정밀 3차원 수치모델을 이용한 수치해석을 수행하였다. 수치해석은 열차의 탈선하중을 해석적으로 모사하고자 정적상태의 극한하중조건으로 적용하였으며, 앵글형 탈선방지 가드레일, 레일, 차륜의 실제도면을 이용하여 모델링하였다. 손상현황조사와 수치해석 결과를 비교 분석하여 구성품의 손상에 대하여 공학적으로 규명하고자 하였다.

• 한국국방경영분석학회지
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• 제30권1호
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• pp.92-106
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• 2004

This is a case study which establishes effective ammo issue plan and determines ammo support capability by linking various situations about ammo issue with wargame simulation. Ammo function simulation model has been developed for this matter and it has been proven that the model has significant impact on type of round, parking space for magazine, number of workers and capacity of equipment, etc. during establishing ammo issue plan and determining ammo supply capability. Also, ammo support capability varies significantly depending on tactical damage and MOPP status, etc. ASP's tactical situation, such as magazine damage, MOPP status, type of issuing round, parking space for magazine, number of workers and capacity of equipment, can be reflected when preparing an effective wartime ammo working hour issuing plan for supplying ammo to units through studies results, so that the issuing plan can be realistic and actual.

• BMB Reports
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• 제47권4호
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• pp.209-214
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• 2014

Ultraviolet B (UVB) radiation induces the production of reactive oxygen species (ROS) that promote apoptotic cell death. We showed that cytosolic $NADP^+$-dependent isocitrate dehydrogenase (IDPc) plays an essential role in the control of cellular redox balance and defense against oxidative damage, by supplying NADPH for antioxidant systems. In this study, we demonstrated that knockdown of IDPc expression by RNA interference enhances UVB-induced apoptosis of immortalized human HaCaT keratinocytes. This effect manifested as DNA fragmentation, changes in cellular redox status, mitochondrial dysfunction, and modulation of apoptotic marker expression. Based on our findings, we suggest that attenuation of IDPc expression may protect skin from UVB-mediated damage, by inducing the apoptosis of UV-damaged cells.

• BMB Reports
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• 제44권5호
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• pp.312-316
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• 2011

1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) and its toxic metabolite 1-methyl-4-phenylpyridium ion (MPP$^+$) have been shown to induce Parkinson's disease-like symptoms as well as neurotoxicity in humans and animal species. Recently, we reported that maintenance of redox balance and cellular defense against oxidative damage are primary functions of the novel antioxidant enzyme cytosolic NADP$^+$-dependent isocitrate dehydrogenase (IDPc). In this study, we examined the role of IDPc in cellular defense against MPP$^+$-induced oxidative injury using PC12 cells transfected with IDPc small interfering RNA (siRNA). Our results demonstrate that MPP$^+$-mediated disruption of cellular redox status, oxidative damage to cells, and apoptotic cell death were significantly enhanced by knockdown of IDPc.

• 한국소음진동공학회:학술대회논문집
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• 한국소음진동공학회 2003년도 추계학술대회논문집
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• pp.21-32
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• 2003

Developments and applications of the structural health monitoring (SHM) systems have become active particularity for long-span bridges in Korea. They are composed of sensors, data acquisition system, data transmission system, information processing, damage assessment, and information management. In this paper, current status of research and application activities on SHM systems for civil infra-structures in Korea are briefly introduced by 4 parts: (1) current status of bridge monitoring systems on existing and newly constructed bridges, (2) research and development activities on smart sensors such as optical fiber sensors and piezo-electric sensors, (3) structural damage detection methods using measured data, and (4) a test road project for pavement design verification and enhancement by the Korea Highway Corporation. Finally the R＆D activities of a new engineering research center entitled Smart Infra-Structure Technology Center at Korea Advanced Institute of Science and Technology are also briefly described.

• 한국지진공학회:학술대회논문집
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• 한국지진공학회 2006년도 학술발표회 논문집
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• pp.358-365
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• 2006

In this study, fragility curves of continuous buried pipelines subjected to transverse PGD (permanent ground deformation) due to liquefaction are proposed. For the waterworks system, continuos buried pipelines made of ductile iron, poly ethylene, and poly vinyl chloride are analyzed and fragility curves are drawn. Fragility curves are based on the repetitive analyses results and formulated with the dominant factors of behaviour of buried pipeline. With the use of fragility curves, engineers can estimate the status of damage of buried pipeline without overall knowledge of relevant features. Especially, fragility curves proposed in this study will act as a major module of earthquake loss estimation method. Moreover, critical value of magnitude and width of transverse PGD (by which the full damage status of buried pipelines are induced) are estimated. With the use of regression curves of these values, pre evaluation of seismic safety of buried pipelines located within liquefaction hazardous region will be possible.