• 혜화의학회지
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• 제8권1호
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• pp.379-401
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• 1999

The effect of KamiTongJonHaaATang extracts on hypercholesterolemia, platelet aggregation, pulm onary thrombosis, KCN-induced coma, forcal brain ischemia, cytotoxicity of PC12 cells induced by amyloid ${\beta}$ protein(25-35), and NO production in RAW cells stimulated lipopolysaccharide were investigated, respectively. The results were summarized as follows; 1. KTJHAT extracts showed a significant decrease of serum total cholesterol, triglyceride, phospholipid, LDL-cholesterol, and VLDL-cholesterol in hypercholesterolemia induced by 2% cholesterol diet in NZW rabbit. 2. KTJHAT extracts induced a significant inhibition of human platelet aggregation induced by thrombin and ADP but did not affect human platelet aggregation induced by collagen. 3. KTJHAT extracts showed a protective effect on pulmonary thrombosis induced by collagen and epinephrine. 4. KTJHAT extracts prolonged the duration of KCN-induced coma. 5. KTJHAT extracts showed a significant decrease of brain ischemic area and edema in MCA occlusion. Also, KTJHAT extracts showed a decrease of neurologic grade in hind limb but did not affect neurologic grade in fore limb. 6. KTJHAT extracts showed a protective effect on cytotoxicity of PC 12 cells induced by amyloid ${\beta}$ protein(25-35) in a dose dependent manner. 7. KTJHAT extracts showed a significant decrease of NO production in RAW cells induced by lipopolysaccharide. These results suggested that KTJHAT extracts might be usefully applied for prevention and treatement of thrombosis and brain damage.

• Childhood Kidney Diseases
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• 제13권1호
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• pp.56-62
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• 2009

목 적 : 방광요관 역류증 환아의 단회뇨에서 요단백 및 효소(Microalbumin, NAG, ${\beta}_2$ MG)의 배설을 측정하여 방광요관 역류의 정도나 신손상을 조기에 예측 할 수 있는 지표로 의미가 있는지 알아보고자 하였다. 방 법 : 요로감염증으로 진단 받았던 91명의 환아 중 방광요관 역류와 신결손이 없었던 환아 I군 (n=62), 신결손은 없이 방광요관 역류만 있었던 환아는 II군(n=10), 신결손 및 방광요관 역류증을 모두 가지고 있었던 환아는 III군(n=19)으로 분류하여 아침첫 소변에서 microalbumin, NAG, ${\beta}_2$ MG를 측정하여 평균값을 비교하였다. 방광요관 역류 grade에 따라 VUR Grade I, II, III은 역류의 정도가 낮은 군으로 VUR grade IV, V는 역류가 높은 군으로 분류하여 요중 Microalbumin, NAG, ${\beta}_2$ MG값을 비교하였다. 결 과 : 단회뇨에서 측정한 microalbumin 값은 역류와 신결손이 있는 군이 없는 군과 비교하여 의미있게 증가되어 있었다(microalbumin: $42.3{\pm}27.2\;mg/gCr$ VS $25.2{\pm}10.9\;mg/gCr$, P<0.05). 단회뇨${\beta}_2$ MG, NAG의 평균값의 각 군간의 비교에서는 통계학적인 유의성이 없었다. 방광요관 역류가 높은 군에서 낮은 군보다 microalbumin 측정치가 의미 있게 증가되었다($23.4{\pm}7.7\;mg/gCr$ VS $39.3{\pm}22.1\;mg/gCr$, P<0.05). 결 론: 요로감염으로 진단받은 방광요관 역류증 환아에서 역류 정도와 역류성 신병증으로의 진행 여부를 예측하는 지표로 단회뇨의 microalbumin 측정이 유용하며, 외래에서 추적 관찰에 간편하게 이용할 수 있고 환아와 보호자의 순응도 상승에도 효과가 있을 것으로 기대된다.

• Conservation and Restoration of Cultural Heritage
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• 제1권1호
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• pp.29-37
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• 2012

The West Stone Pagoda at Gameunsaji Temple Site constructed in the 7th century is mainly composed of dark grey dacitic tuff bearing small numerous dioritic xenoliths. These xenoliths resulted in small holes due to differential weathering process from the host rocks. Physical strength of the pagoda was decreased due to weathering and damage caused by petrological, biological and coastal environmental factors. The southeastern part of the pagoda was extremely deteriorated that the rock surface showed exfoliation, fracture, open cavity, granular decomposition of minerals and salt crystallization by seawater spray from the eastern coast. The stone blocks were intersected by numerous cracks and contaminated by subsequent material such as cement mortar and iron plates. Also, the pagoda was colonized by algae, fungi, lichen and bryophytes on the roof rock surface and the gaps between the blocks. As a result of ultrasonic test, the rock materials fell under Highly Weathered Grade (HW) or Completely Weathered Grade (CW). Thus, conservational intervention is essentially required to prevent further weakening of the rock materials.

• 한국유기농업학회지
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• 제14권3호
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• pp.251-266
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• 2006

This study was surveyed and analyzed in 2005 year for environmentally-friendly rice's production 78 farmers in korea. The major results was as follows: The average age of farmers were 54 years old, the experiences of environmentally-friendly rice's production farms was 7.4 years, the cultivated scales of environmentally-friendly rice's production was 3.4ha. The 74%'s Farmers of all unified rice's breeds for rice's production of high-grade in quality, the ranking of rice's breeds selection were the high-grade rice's breeds of government>japan rice's breeds. The control of damage by blight and insects were needed environmentally-friendly control, the endured study of this control were very important. To cut down cost of the environmentally-friendly rice for income security of farmers and sustenance of farming will. To receive reasonable price of environmentally-friendly rice, the brand image were raised to consumers, the variety and miniaturization of rice packaging unit were needed in view of consumers. In addition to must be campaigns of publicity through the press and event to consumers, were managed the exchange of rice goods and exchanged e-mail together consumers for the maintenance of confidence. To drive direct marketing between environmentally-friendly rice farmers and consumers through experiential marketing, to diversify the marketing channel. To strengthen public relations at regional level and relationship at the consumers.

• 설비공학논문집
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• 제22권12호
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• pp.881-890
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• 2010

As Influenza A virus(H1N1) has been spreading more rapidly around globe, the study on the airborne disease which is transimitted through the respiratory system is on the rise. In this study, the multizone simulation of the public building against bioviolence is performed in the case of unexpected spread of microbial contaminants, such as bioviolence agent, Influenza A, Smallpox, B. anthrax and transport and control characteristics of above three kinds of bioviolence agents are evaluted. Results suggest that Influenza A and Smallpox which has small mean diameter can be more removable than B. anthrax by using high UVGI grade condition and B. anthrax which has large mean diameter can be more removable than Influenza A and Smallpox by using high filter grade condition. Results also suggest that installing a combined air treatment system is more effective to reduce the damage and engineers will use immune building technology for removing the bioviolence agents effectively.

• Nuclear Engineering and Technology
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• 제53권2호
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• pp.572-582
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• 2021

This study investigated the creep and creep crack growth (CCG) behavior of the base metal (BM), weld metal (WM), and heat affected zone (HAZ) in a Gr. 91 weldment, which was made by a shield metal arc weld process. A series of tensile, creep, and CCG tests were performed for the BM, WM, and HAZ at 550 ℃. Creep behavior of the BM, WM, and HAZ was analyzed in terms of various creep laws; Norton's power-law, Monkman-Grant relation and damage tolerance factor (λ), and their constants were determined. In addition, each CCGR law for the BM, WM, and HAZ was proposed and compared in terms of a C^*-fracture parameter. The WM and HAZ revealed faster creep rate, lower rupture ductility, and faster CCGRs than the BM, but they showed a similar behavior in the creep and CCG. The CCGRs obtained in the present study exhibited a marginal difference when compared with those of RCC-MRx of currently elevated design code in France. A creep crack path in the HAZ plane progressed towards a weak fine-grained HAZ adjacent to the BM.

• Geomechanics and Engineering
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• 제25권2호
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• pp.123-134
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• 2021

In this paper, the carbon fiber reinforced plastic (CFRP) grids embedded in polymer cement mortar (PCM) shotcrete (CFRP-PCM method) was conducted to repair the degraded tunnel linings with a cavity. Subsequently, the reinforcing effect of the CFRP-PCM method under different degrees of lining deterioration was quantitatively evaluated. Finally, the limit state design method of the M-N interaction curve was conducted to determine whether the structure reinforced by the CFRP-PCM method is in a safe state. The main results indicated that when the cavity is at the shoulder, the lining damage rate is more serious. In addition, the remarkably reinforcing effect on the degraded tunnel linings could be achieved by applying a higher grade of CFRP grids, whereas the optimization effect is no longer obvious when the grade of CFRP grids is too high (CR8); Furthermore, it is found that the M-N numerical values of the ten reinforcing designs of the CFRP-PCM method are distributed outside the corresponding M-N theoretical interaction curves, and these designs should be avoided in the corresponding reinforcing engineering.

• Geomechanics and Engineering
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• 제24권6호
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• pp.505-518
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• 2021

The present paper has been carried out to understand the effects of impact loading on the rock tunnels, constructed in different region corresponding to varying unconfined compressive strength (UCS), through finite element method. The UCS of rockmass has substantial role in the stability of rock tunnels under impact loading condition due to falling rocks or other objects. In the present study, Dolomite, Shale, Sandstone, Granite, Basalt, and Quartzite rocks have been taken into consideration for understanding of the effect of UCS that vary from 2.85 MPa to 207.03 MPa. The Mohr-Coulomb constitutive model has been considered in the present study for the nonlinear elastoplastic analysis for all the rocks surrounding the tunnel opening. The geometry and boundary conditions of the model remains constant throughout the analysis and missile has 100 kg of weight. The general hard contact has been assigned to incorporate the interaction between different parts of the model. The present study focuses on studying the deformations in the rock tunnel caused by impacting load due to missile for tunnels having different concrete grade, and steel grade. The broader range of rock strength depicts the strong relationship between the UCS of rock and the extent of damage produced under different impact loading conditions. The energy released during an impact loading simulation shows the variation of safety and serviceability of the rock tunnel.

• 국제학술발표논문집
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• The 9th International Conference on Construction Engineering and Project Management
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• pp.929-936
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• 2022

In the U.S., the state, local, tribe, and territorial governments seek funding from the federal government through the Public Assistance program to carry out these recovery works. In this paper historic public assistance data between 1998 and 2021 have been analyzed to derive several insights such as: types of disasters causing the most damage, states requiring more support, net present value of the federal expense etc. This paper has found that the states requiring more support from the federal government are not always the states suffering the maximum losses from the disasters. It has also found that the net present value of the federal expense between 1998 and 2020 to restore, repair, reconstruct, or replace disaster damaged roads and bridges across the U.S. is $15 billion in 2021 values. Moreover, this paper has tested the correlation between the states' public assistance funds requirements and the existing condition and performance of roads and bridges as revealed by the American Society of Civil Engineer's infrastructure grade card. It has found a weak correlation between these two. The outcomes of this paper can be used by the decision makers to analyze the viability of any possible alternative to the exiting public assistance program. The insights can also help in better decision making in pre-disaster preparation and post-disaster funds allocation.

• KEPCO Journal on Electric Power and Energy
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• 제4권1호
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• pp.25-31
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• 2018

A boiler system transforms water to pressured supercritical steam which drives the running of the turbine to rotate in the generator to produce electricity in power plants. Materials for building the tube system face challenges from high temperature creep damage, thermal fatigue/expansion, fireside and steam corrosion, etc. A database on the creep resistance strength and steam oxidation of the materials is important to the long-term reliable operation of the boiler system. Generally, the ferritic steels, i.e., grade 1, grade 2, grade 9, and X20, are extensively used as the superheater (SH) and reheater (RH) in supercritical (SC) and ultra supercritcal (USC) power plants. Currently, advanced austenitic steel, such as TP347H (FG), Super304H and HR3C, are beginning to replace the traditional ferritic steels as they allow an increase in steam temperature to meet the demands for increased plant efficiency. The purpose of this paper is to provide the state-of-the-art knowledge on boiler tube materials, including the strengthening, metallurgy, property/microstructural degradation, oxidation, and oxidation property improvement and then describe the modern microstructural characterization methods to assess and control the properties of these alloys. The paper covers the limited experience and experiment results with the alloys and presents important information on microstructural strengthening, degradation, and oxidation mechanisms.