• Korean Journal of Clinical Laboratory Science
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• v.48 no.4
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• pp.296-303
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• 2016

This study was performed to evaluate the effect of hemoglobin (Hb) on bone mineral density (BMD) in university students by performing a quantitative analysis. The subjects included healthy university students aged 20 to 30 years. Although osteoporosis has traditionally been considered as a disease of aging women, it is becoming an increasingly concerning male health problem. Diagnosis of osteoporosis is calculated with a quantitative assessment of BMD. Laboratory blood and urine tests are mainly used with low BMD or fragility fractures to identify any possible causes of bone metabolism disorders. In this study, there was no difference in BMD according to gender. The average red blood cell (RBC), Hb, and Hematocrit (HCT) were significantly higher in males (p<0.01). The correlation between lumbar spine, skeletal muscle mass (SMM), and basal metabolic rate (BMR) was statistically significant (p<0.01). Hb showed a 51.7% statistical influence on BMD by multiple regression analysis. These findings are useful to understand the relationship between BMD and Hb; lower Hb level is associated with lower BMD. The Hb level was the strongest predictor of abnormal BMD. In conclusion, this study showed that a low Hb value was significantly correlated with low bone mass, suggesting that a low Hb value is a risk factor for changes in bone turnover that leads to a decrease bone density.

• Journal of Food Hygiene and Safety
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• v.18 no.4
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• pp.195-201
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• 2003

An easily available, simultaneous identification/determination procedure for sildenafil, homosildenafil, tadalafil, vardenafil in adulterated health related foods was established by using a combination of three different analytical methods; thin layer chromatography(TLC), liquied chromatography-mass spectrometry (LC/MS) and high-performance liquied chromatography (HPLC)/photo-diode-array detector. The sample solution for TLC was applied to silica gel 60 $F_{254}$ plates with ethylacetate/acetonitrile/25%ammonia (90:10:5) as a developing solvent. Spots were located under UV radiation at 254 nm and dragendolfs reagent. Mass spectra of the compounds by LC/MS were investigated with electrospray ionization (ESI) interface, under positive ion mode. The HPLC analysis was performed on a column of capcell pack $C_{18}$ (UG120, 4.6${\times}$250mm I.D. 5 ${\mu}$m)with 0.1% sodium 1-hexansulfonate (in 0.1% phosphoric acid)/acetnitrile (73:27) as a mobile phase, and effluent was minitored with a photo-diode-applied to commercial foods, Sildenafil content was inthe range of 0.4mg/g~360.9 mg/g from 7 out of 35 samples. Homosildenafil content was in the range of 2.2 mg/g~336.0 mg/g from 7 out of 35 samples. Tadalafil content was 429.3 mg/g, 9.6 mg/500 mg from 2 out of 35 samples. The procedure described here is available for the screening of sildenafil, homosildenafil, tadalafil, vardenafil.

• Journal of Microbiology and Biotechnology
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• v.12 no.3
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• pp.457-462
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• 2002

Low Electromagnetic Field (EMF) intensity in the range of $1{\mu}T\;to\;10{\mu}T$(Tesla) was found to enhance the growth of CHO cells and the production of tPA in batch and perfusion cultivations. At $1{\mu}T\;intensity,\;1.3{\times}10^7$ viable cells/ml of maximum cell density and 80 mg/l of maximum tPA production were obtained in batch cultivation, compared to $2.8{\times}10^6$ viable cells/ml and 59 mg tPA/1 in unexposed case (control). A similar trend was observed in the perfusion process, where it was possible to obtain $1.2{\times}10^7$ viable cells/ml of maximum cell density and 81 mg tPA/l of maximum tPA production by more than 80 days of cultivation. However, there was not much difference between $1{\mu}T\;and\;10{\mu}T$ in perfusion cultivation, possibly due to better environmental growth conditions being maintained by continuous feeding of fresh medium into the reactor. On the contrary, both cell growth and tPA production were severely inhibited at higher than 1 mT intensity, showing no growth at 10 mT exposure. Specific growth rate was linearly correlated to specific tPA production rate at $1{\mu}T$EMF intensity, which represents a partially growth-related relationship. It was also found that a large amount of $Ca^2+$ was released at low EMF intensity, even though the cell growth was not much affected. Low EMF intensity significantly improved both cell growth and tPA production, and tPA production seemed to be more affected than the cell growth, possibly due to the changes of cell membrane characteristics. It can be concluded that the elaboration of EMF intensity less than $10{\mu}T$ could improve cell growth and tPA production, but mainly tPA secretion through batch or perfusion process in a bioreactor.

• The Journal of the Korea Contents Association
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• v.16 no.10
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• pp.435-442
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• 2016

Obesity extends the global economic burden and it causes that the failure of a reduction of physical activity, and diet management. In this work, nutritional information and personalized diet based on calorie supply system and is discriminatory utilized the obesity-related SNP information in order to recommend a personalized functional foods. This study performed a GWAS analysis for the excavation of a Korean-specific and obesity-related SNP, which utilizes genetic information were recommended by entering a personalized diet in accordance with the SNP genotype-phenotype information. In addition, we integrated Database with relation of nutrient for utilizing the USDA Food information and it was applied to recommend with Sickdanome. As a result, the obesity-related SNP information was confirmed in the sample which has the normal value BMI. In this study, we have recognized that the phenotype information related obesity, BMI is inconsistent with the SNP genotype information. This result is shown that it is necessary to provide the personalized dietary SickdanOme recommendation based on the both pheotype-genotype information.

• 한국문화재보존과학회:학술대회논문집
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• 2001.11a
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• pp.49-58
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• 2001

The antibacterial and insecticidal properties of ethanol extracts and volatile components extracted from Eugenia caryophyllata, Boswellia carerii, Agastache rugosa, Aristolochia contorta, and Aquilaria agallocha were evaluated. The ethanol extract and volatile component of E. caryophyllata showed strong antimicrobial effect against all strains (Mucor hiemalis, Aspergillus niger, Penicillium funiculosum, Trichodema viride) and the volatile component of B. carterii showed antimicrobial effect against all strains except T. viride. The ethanol extract of E. caryophyllata and A. contorta showed $100\%\;and\;32\%$ mortality against Reticulitermes spertus kyushuensis Morimoto for 48 hours and 72 hours, respectively. In the case of volatile component, R. aryophyllata showed $100\%\;and\;20\%$ mortality against R. spertus and Lyctus linearis GOZE, respectively. The main constitute, eugenol $(92\%)$ among nine components from volatile component of E. aryophyllata were identified as antibacterial active substance.

• Analytical Science and Technology
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• v.7 no.3
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• pp.329-338
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• 1994

The retention behaviors of natural gas components were studied on a single column by gas chromatography. The dead time, $t_0$ was obtained by using extrapolation of homologous series to determine capacity factors. The plots of retention data for homologous series and carbon number at different temperatures were shown to converge into a single point, which point was determined as a dead time. The results of the effect of temperature on the column efficiency for n-butane exhibited the plate number, N incerased with temperature, but the resolution among the fast eluted components decreased. The adsorption enthalpy (${\Delta}H^0{_{ads}}$) for each component on 28% DC 200 stationary phase was determined, and in order to investigate the retention behaviors of natural gas components the regression analysis of log $t_R$, log k' and log ${\alpha}$ vs. van der Waals volume(Vw), molecular connectivity index(X) and hydrophobic fragmental constant(f) were carred out. Good correlation was found between log k' vs. Vw, and log k' vs. f. The correlations between the physical properties of natural gas and the physical parameters were investigated by the linear regression analysis. The relationships between Vw vs. molecular weight and heating value(${\Delta}H_{comb}$), X vs. boiling point, and f vs. molecular weight, boiling point and heating value exhibited the high correlation coefficient more than 0.99. Using the regression equation between the heating value of natural gas and Vw the predicted heating values from $C_6$ to $C_{10}$ showed good agreement with those reported in the literature within 0.2% relative error.

• Korean Journal of Fisheries and Aquatic Sciences
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• v.12 no.1
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• pp.1-6
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• 1979

본연구에서는 그물어구의 상사를 지배하는 무차원수 K를 $$K=\frac{{\nu}^n\rho_wv^{2-n}}{{d^{1+n}(\rho-\rho_w)}$$ d, p: 재료의 직경 및 밀도 $\nu,\rho_w,v$: 물의 동점성계수, 밀도 및 속도으로 정하고, 여기에서의 직경의 비를 결정하는 방법에 따라 실물과 모형과의 상사를 완전하게 그리고 근사적으로 만족시키는 조건들을 구하였다. 즉, 원전한 상사한 경우는 직경의 비를 축척비와 같게 하고, 나아가서 다른 모든 치수의 비도 축척비와 같게 함으로써 만족된다고 하였으며, 측사적 상사의 경우느 직경의 비가 축척비 $(\frac{\lambda_2}{\lambda_1})$와 같지 않아도 된다고 하여, 그물실의 직경 d, 코의 크기 $\iota$ 및 콧수 N의 비를 $$\frac{d_2}{d_1}=\frac{\iota_2}{\iota_1}=\frac{\lambda_2}{\lambda_1}{\cdot}\frac{N_1}{N_2}$$ 으로, 줄의 직경 d', 길이 $\iota'$ 및 밀도 $\rho'$의 비를 $$\frac{d_2'}{d_1'}=\sqrt{{\frac{\lambda_2}{\lambda_1}}\cdot{\frac{d_2}{d_1}}\cdot{\frac{\rho_2-\rho_{w2}}{\rho_1-\rho_{w1}}\cdot{\frac{\rho_1'-\rho_{w1}}{\rho_2'-\rho_{w2}}}}$$, $\frac{\iota_2'}{\iota_1'}=\frac{\lambda_2}{\lambda_1}$로, 부속구의 치경 $d'$, 밀도 $\rho'$ 및 수 $N'$의 비를 $$\frac{N_2'}{N_1'}=(\frac{\lambda_2}{\lambda_1})^2(\frac{d_2}{d_1})(\frac{d_1'}{d_2'})\frac{(\rho_2-\rho_{w2})}{(\rho_1-\rho_{w1})}\frac{(\rho_1'-\rho_{w1})}{(\rho_2'-\rho_{w2})}$$으로 정하였다. 이렇게 정해진 모형어구에 대해 유속 v의 비느 $K_1=K_2$로부터 $$(\frac{u_2}{u_1})^{2-n}=(\frac{\nu_2}{\nu_1})^{-n}\;(\frac{\rho_{w1}}{\rho_{w2}})\;(\frac{\rho_2-\rho_{w2}}{\rho_1-\rho_{w1}})\;(\frac{d_2}{d_1})^{1+n}$$으로 주어지므로, 이를 이용하여 어구저항 D 및 그물감의 다리에서의 장력 $\tau$의 비를 $$\frac{D_2}{D_1}=\frac{d_2(\rho_2-\rho_{w2})}{d_1(\rho_1-\rho_{w1})}(\frac{\lambda_2}{\lambda_1})^2$$ $${\frac{\tau_2}{\tau_1}=\frac{d_2\iota_2(\rho_2-\rho_{w2})}{d_1\iota_1(\rho_1-\rho_{w1})}\;{\cdot}\frac{\lambda_2}{\lambda_1}$$로 정하였다.

• Journal of KIISE:Software and Applications
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• v.36 no.2
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• pp.169-177
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• 2009

In this paper, we propose a new shot boundary detection method which is optimized for news video story parsing. This new news shot boundary detection method was designed to satisfy all the following requirements: 1) minimizing the incorrect data in data set for anchor shot detection by improving the recall ratio 2) detecting abrupt cuts and gradual transitions with one single algorithm so as to divide news video into shots with one scan of data set; 3) classifying shots into static or dynamic, therefore, reducing the search space for the subsequent stage of anchor shot detection. The proposed method, based on singular value decomposition with incremental clustering and mercer kernel, has additional desirable features. Applying singular value decomposition, the noise or trivial variations in the video sequence are removed. Therefore, the separability is improved. Mercer kernel improves the possibility of detection of shots which is not separable in input space by mapping data to high dimensional feature space. The experimental results illustrated the superiority of the proposed method with respect to recall criteria and search space reduction for anchor shot detection.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.13 no.12
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• pp.6167-6175
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• 2012

This study is experimental analysis to verify heating efficiency of Ondol in floor heating panel developed. For this one, an experiment tests producing an each test speciment and measuring heating efficiency. The result of an experiment, supplying hot water temperature is $45^{\circ}C$ and the result of measuring on parts temperature of test speciment on supplying for 8 hours, mortar surface that is superstructure plumbing of heating system developed is $49.4^{\circ}C$, the gap of piping on center of mortar surface is $44.1^{\circ}C$ and airspace is proved $25.3^{\circ}C$. In floor structure of standards, mortar surface is $46.2^{\circ}C$, the gap of piping on center of mortar surface $37.7^{\circ}C$ and airspace is $24.7^{\circ}C$. On the other hand, energy consumption accumulating of development technology is identified, in case of hot-water supply on $45^{\circ}C$ as 4,646 kcal and in existing technology, as 4,814 kcal. developing technology is verified and lower than existing technology.

• Clinical and Experimental Reproductive Medicine
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• v.30 no.3
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• pp.241-248
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• 2003

Objective: The purpose of this study was to evaluate the survival rate of vitrified blastocyst according to the freezing vessels, equilibration time in cryoprotectant and artificial dehydration method. Methods: Human blastocysts were vitrified after loading onto the plastic straw, open-pulled straw (OPS), electron microscopy grid (EM grid) for 1.5 min or 3 min. They also were directly plunged into LN2 within 30sec. For artificial shrinkage of blastocysts, 36 gauge fine needle was pushed at the cellular junction of the trophectoderm into the blstocoele cavity until it shrank without damage of inner cell mass. Results: The survival rate of vitrified blastocysts on plastic straw, OPS, EM grid as freezing vessels were 26.7, 13.0 and 60.5%, respectively. The survival rate of EM grid was significantly higher than that of plastic straw and OPS (p<0.05). For 1.5 min equilibrium, the survival rates of early blastocyst (EB), middle blastocyst (MB) and late blastocyst (LB) were 64.4, 81.0, and 20.0% respectively. For 3 min equilibrium, the survival rates of EB, MB, and LB were 69.9, 50.0 and 57.5% respectively. The survival rates of EB and MB were significantly higher than that of LB in 1.5 min equilibrium group (p<0.05), however, the significance was not observed in 3 min equilibrium groups. In cytoplasmic shrinkage before vitrification, the survival rates of EB, MB and LB were 92.9, 100 and 75.9% respectively. The survival rate of MB was significantly higher than that of LB (p<0.05). The survival rates of vitrified blastocysts by artificial dehydration and slow-frozen blastocysts were not significantly different as 88.9 and 66.7%, respectively. Conclusion: This study showed that the vitrification of human blastocysts using EM grid and artificial dehydration is an effective method. Therefore, these methods would be an useful techniques for blastocyst cryopreservation.