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The Effects of Chungkukjang Powder Supplements on the Regulation of Blood Glucose and Inflammation in Diabetic Rats (청국장 분말 첨가식이가 당뇨 쥐의 혈당과 염증조절에 미치는 영향)

  • Yang, Kyung-Mi
    • Korean journal of food and cookery science
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    • v.31 no.2
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    • pp.118-127
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    • 2015
  • In this study, the effect of Cheonggukjang powder were investigated on the regulation of blood glucose and inflammatory in STZ-induced diabetic rats. The experimental diet used this study were three kinds of Cheonggukjang, which were soybean Cheonggukjang, Yakkong Cheonggukjang and black foods such as black rice, black sesame seeds, and sea tangle added Yakkong Cheonggukjang powder. The experimental animals were divided into 5 groups and fed experimental diets for 7 weeks; non-diabetes with normal diet group (C), diabetes with normal diet (DC), diabetes with soybean Cheonggukjang (DS), diabetes with Yakkong Cheonggukjang (DY), and diabetes with Yakkong black foods added Cheonggukjang (DYB). Blood glucose and insulin resistance of STZ-induced diabetic groups were were significantly higher than C group. But insulin levels and insulin secertory of STZ-induced diabetic groups were significantly lower than C group. However, supplementation of Yakkong or black foods added Yakkong Cheonggukjang were proven to regulation them. In diabetic group, free fatty acid level was significantly increased than C group, but this contents was significantly decreased supplementation of soybean Cheonggukjang. Leptin and adiponectin levels were significantly decreased in STZ-induced diabetic groups.

A Study on the Vegetation Structure of Abies koreana Forest in Yeongsil Area of Hallasan Mountain (한라산 영실지역 구상나무림의 식생구조 연구)

  • Song, Kuk-Man;Kang, Young-Je
    • Journal of Environmental Science International
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    • v.25 no.1
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    • pp.57-65
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    • 2016
  • This study's purpose was to provide basic data for the monitoring of ecological changes caused by change of vegetation structure of Abies koreana forest in a study site susceptible to climatic change in Yeongsil area of Hallasan Mountain, Jeju Island. Surveys revealed this: in Yeongsil area of Hallasan Mountain, per 1 ha of A. koreana forests, total number 1,781, and A. koreana number 989, accounting for 55.5% of the total number of trees. 190 A. koreana or 19.2% were found to be dead. For the number of individual trees by DBH, trees standing 5 cm - 10 cm tall formed the largest portion at 39.9%, and in the case of other trees except A. koreana, the number of individual trees below 5 cm accounted for 23.5% of the total number of trees. The survey of importance by height revealed this: at the top level, the importance of A. koreana was the highest at 106.23, but the sum of importance of temperate deciduous broad-leaved trees (Prunus maximowiczii, Quercus mongolica, and Taxus cuspidata) was higher at 142.84 than that of A. koreana. The analysis of species diversity revealed 0.645 species diversity for the tree layer and 0.817 for the shrub layer; for evenness, 0.549 for the tree layer and 0.664 for the shrub layer; for dominance value; 0.451 for the tree layer and 0.336 for the shrub layer. The analysis of tree vitality revealed that for the A. koreana forests in Yeongsil, the composition ratio of A. koreana by type is AS type>AL type>DS type>DB type, and that of the other trees is AL type>AS type>AF type>AB type. Compared with the forests in other areas, the A. koreana forests in the Yeongsil area have a very high occurrence rate of dead trees, and a high importance of trees is shown in the deciduous broad-leaved tree forests. Compared with the A. koreana forests in the Jindallaebat area, with the same level above sea, the vegetation structures are fast changing. Also, due to dryness and other non-physical environmental changes caused by a lack of rainwater and dry winds in winter, dead trees are fast increasing in number. Environmental changes such as climate change diversely affect the maintenance of A. koreana in individual areas, and if environmental changes are fast and continue long, of the A. koreana forest areas in the Hallasan Mountain, the A. koreana forests in the Yeongsil area will decrease fastest in number and will experience changes in the vegetation structure. Thus, it is necessary to survey the vegetation changes in A. koreana forests, which are distributed in all directions but are centered on Hallasan Mountain, and to thus conduct long-term monitoring and research.

Calcium Ionization Characteristics and In vitro Bioavailability Derived from Natural Calcium Sources (천연칼슘소재의 이온화 특성 및 In vitro 칼슘 이용률)

  • Jang, Se-Young;Jeong, Yong-Jin
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.42 no.4
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    • pp.497-504
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    • 2013
  • This study examined the characteristics of ionized calcium and in vitro calcium bioavailability rate of calcium from four natural sources: shellfish shell, oyster shell, starfish, egg shell. The levels of dissolved calcium and calcium ions increased at different concentrations of natural calcium (up to 8.0% (w/v)). However, there were insignificant differences in the levels of dissolved calcium and calcium ions between samples at calcium concentrations above 8.0% (w/v). In addition, no significant differences were observed (depending on the calcium source and concentration) with an ionization yield of about 90%. The temperature of the solutions also had little influence on the ionization of calcium. The highest calcium ion content was observed when solutions were left to dissolve calcium for 18 hours. The highest in vitro calcium bioavailability rate achieved among the different calcium solutions was BS (67.3%), with overall bioavailability rates about two times higher than the rates observed in commercially sold calcium supplements and natural calcium. In addition, the in vitro calcium bioavailability rate for ionized calcium in market milk, soy milk, and orange juice was more than twice as high as calcium carbonate. Overall, we expect a high and diverse bioavailability of ionized calcium from natural resources.

Bush Growth and Fruit Quality of 'Duke' Blueberry Influenced by Nutrition Supply Periods in Unheated Plastic House (무가온 하우스 재배 '듀크' 블루베리에 대한 양분공급시기가 수체생육, 과실품질, 수량에 미치는 영향)

  • Cheon, Mi Geon;Lee, Young Suk;Kim, Young Bong;Kumarihami, H.M. Prathibhani C.;Kim, Jin Gook
    • Journal of Bio-Environment Control
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    • v.29 no.4
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    • pp.421-427
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    • 2020
  • In this study, we investigated the effect of nutrient supply periods on the fruit growth and quality of 'Duke' blueberry. The nutrient solution was contained with NO3-N 4.6, NH4-N 3.4, PO4-P 3.3, K 3.0, Ca 4.6, and Mg 2.2 mmol·L-1, and EC in the nutrient solution was 1.5 ds.m-1. In 2017 and 2018, an individual blueberry bush was supplied with 8 L of the nutrient solution per week. In 2018, the drainage water quality of growing medium and fruit quality was investigated. The nutrient supply was started from April 01, and stopped at 15 days intervals as follows, 15 days before final harvest, at the final harvest date (June 30), 15 days after final harvest (DAFH), 30 DAFH, 45 DAFH, and 60 DAFH. The content of inorganic components in the growing medium was not significantly different by the stop time of nutrient supply, but the content of phosphorus (P2O5) tended to increase with the delay of stop time of nutrient supply. There were no significant differences in the fruit quality characteristics in terms of size, sugar content, and acidity among the different stop time of nutrient supply. The blueberry yield was tended to decrease with the delay of periods of nutrient supply, while the lowest yield of 1.8 kg was recorded when nutrient supply stopped at 45 and 60 DAFH.

A Name-based Service Discovering Mechanism for Efficient Service Delivery in IoT (IoT에서 효율적인 서비스 제공을 위한 이름 기반 서비스 탐색 메커니즘)

  • Cho, Kuk-Hyun;Kim, Jung-Jae;Ryu, Minwoo;Cha, Si-Ho
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.19 no.6
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    • pp.46-54
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    • 2018
  • The Internet of Things (IoT) is an environment in which various devices provide services to users through communications. Because of the nature of the IoT, data are stored and distributed in heterogeneous information systems. In this situation, IoT end applications should be able to access data without having information on where the data are or what the type of storage is. This mechanism is called Service Discovery (SD). However, some problems arise, since the current SD architectures search for data in physical devices. First, turnaround time increases from searching for services based on physical location. Second, there is a need for a data structure to manage devices and services separately. These increase the administrator's service configuration complexity. As a result, the device-oriented SD structure is not suitable to the IoT. Therefore, we propose an SD structure called Name-based Service-centric Service Discovery (NSSD). NSSD provides name-based centralized SD and uses the IoT edge gateway as a cache server to speed up service discovery. Simulation results show that NSSD provides about twice the improvement in average turnaround time, compared to existing domain name system and distributed hash table SD architectures.

Improvement Effect of Sprout of Coix lacryma-jobi var. mayuen Stapf Water Extract on DSS-Induced Ulcerative Colitis in Mice. (DSS로 궤양성 대장염 유발된 동물모델에서 의이아(薏苡芽) 열수 추출물의 개선 효과)

  • Kim, Min Ju;Shin, Mi-Rae;Lee, Jin A;Park, Soon-Ae;Park, Hae-Jin;Lee, Jeong Hoon;Roh, Seong-Soo
    • The Korea Journal of Herbology
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    • v.35 no.6
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    • pp.21-28
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    • 2020
  • Objectives : The objective of this study was to investigate the improvement effect of Sprout of Coix lacryma-jobi var. mayuen Stapf water extract (SC) on the dextran sulfate sodium (DSS)-induced ulcerative colitis mice. Methods : The antioxidant activity of SC was measured through total polyphenol and total flavonoid content in vitro. The experiment was conducted with seven-week-old male Balb/c mice. After 1 week adaptation, acute colitis was induced by oral administration of 5% DSS dissolved in drinking water, for 7 days. And normal mice received drinking water without DSS throughout the entire experimental period. For each experiment, the mice were divided into 4 groups and 24 colitis mice were arbitrarily allocated into 3 groups (n = 8/group); Normal group, Control group, SC 100 mg/kg treated group (SCL), SC 200 mg/kg treated group (SCH). Serum and colon tissues were collected after one weeks of drug administration. Results : ROS levels, ONOO- levels, AST, and ALT in serum were decreased in SC treated groups compared to the control group. Western blotting measurements of Nrf2, HO-1, SOD, catalase, GPx-1/2, IL-4, IL-10, and Bcl2 showed that the SC treated groups was increased compared to the Control group. Also, western blot measurements of NF-κBp65, p-IκBα, COX-2, iNOS, TNF-α, IL-1β, Bax, and Caspase-3 showed that the SC treated groups was reduced compared to the Control group. Conclusion : Taken together, these results suggest that SC treatment can attenuate the DSS-induced colitis though inhibiting NF-κB pathway and enhancing Nrf2 pathway. Therefore, SC was the potential to be used as a natural therapeutic drug.

A Study on the Performance Improvement of Turbo Coded OFDM Systems Considering Frequency Offset (주파수 오프셋을 고려한 Tued OFDM 시스템의 성능 개선에 관한 연구)

  • 이영춘;박기식
    • Journal of the Korea Institute of Information and Communication Engineering
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    • v.5 no.5
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    • pp.908-915
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    • 2001
  • In this paper, it is analyzed theoretically that the performance degradation, caused by carrier frequency offset, in an OFDM/M-ary PSK system. Then, when Turbo coding is adopted to an OFDM/M-ary PSK system, the degree of performance enhancement is evaluated. Finally, the maximum frequency offset is calculated to satisfy the BER performance required in a Turbo coded OFDM/M-ary PSK system. As results of analysis, it is shown that the more the number of M-ary is, the worse the BER performance is. Moreover, 7dB, 9dB, and 17dB of $E_b/N_o$ are required in QPSK, 8PSK and 16PSK systems, respectively in order to satisfy the error performance, $BER=10^{-3}$ for voice communication. If $E_b/N_o$ are 10㏈ and 15㏈, the frequency offset should be below 0.05 and 0.075, respectively, for voice communication. When Turbo coding is adopted to an OFDM/M-ary PSK system, the less the number of M-ary is, the greater the performance enhancement of Turbo coding is. If the number of a M-ary system of the system is below 16, it is found that required $E_b/N_o$ is about 8dB to satisfy $BER=10^{-5}$ Moreover, in the system the Turbo coding scheme, voice communication is available with greatly low$E_b/N_o$, and 8dB of $E_b/N_o$ is enough for data communication regardless of the permission range of frequency offset.

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Osteonectin Interacts with Human Nebulin C-terminus in Skeletal Muscle

  • Park, Eun-Ran;Kim, Hyun-Suk;Choi, Jun-Hyuk;Lee, Yeong-Mi;Choi, Jae-Kyoung;Joo, Young-Mi;Ahn, Seung-Ju;Min, Byung-In;Kim, Chong-Rak
    • Biomedical Science Letters
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    • v.13 no.4
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    • pp.263-272
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    • 2007
  • Nebulin is a giant actin binding protein (600-900 kDa) which is specific to skeletal muscle. This protein is known to regulate thin filaments length in sarcomere as a molecular template. The C-terminus of nebulin is located in the Z-disc of muscle sarcomere and is bound to other proteins such like myopalladin, titin, archvillin, and desmin. The N-terminus of nebulin binds to tropomodulin at the pointed ends of the thin filaments. In recent research, nebulin not only found in brain but also expressed in heart, stomach, and liver. So, the roles of nebulin in non-muscle tissue have been studied. However, lack of information or studies on nebulin binding proteins and nebulin function in brain are available so far. Therefore, the current study have investigated a novel binding partner of Nebulin C-terminus by using yeast two-hybrid screening with human brain cDNA library. Nebulin C-terminus, containing simple repeats, serine rich and SH3 domain, interacts with osteonectin C-terminal region. The specific interaction of nebulin and osteonectin were confirmed in vitro by using GST pull-down assay and reconfirmed in vivo by using transfected COS-7 cells with EGFP-tagged nebulin and DsRed-tagged osteonectin. Consequently, this study identified SH3 domain in nebulin C-terminus specifically binds to extracellular Ca-binding (EeC domain in osteonectin. Also, nebulin C-terminus fusion protein colocalized with osteonectin EC domain fusion protein in transfected COS-7 cells. The current study found the interaction between nebulin and osteonectin in human brain for the first time and suggested the nebulin in brain may be associated with osteonectin, as a regulator of cell cycle progression and mitosis.

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Interfacial Properties of Octenyl Succinyl Barley ${\beta}$-Glucan in Emulsion System (유화액 시스템에서 옥테닐 호박산 베타글루칸의 계면 특성)

  • Gil, Na-Young;Kim, San-Seong;Lee, Eui-Seok;Shin, Jung-Ah;Lee, Ki-Teak;Hong, Soon-Taek
    • Journal of the Korean Applied Science and Technology
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    • v.31 no.4
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    • pp.642-652
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    • 2014
  • The synthesis of octenyl succinyl ${\beta}$-gucan (OSA-${\beta}$-glucan) was carried out and its interfacial properties at the oil-water interface and in emulsion systems were investigated. An aqueous ethanol system as a reaction media was used to facilitate the synthesis process; 10% (w/w) ethanol found to be the best as it showed a maximum degree of substitution (DS: 0.0132). FT-IR showed a characteristic absorption spectrum at $1736cm^{-1}$, indicating the esterification of octenyl succinyl groups to ${\beta}$-glucan backbone. As for interfacial tension measurements, it was decreased with increasing concentration of OSA-${\beta}$-glucan in the aqueous phase and when NaCl was added to aqueous OSA-${\beta}$-glucan solution in the range of 0.01 M to 0.1 M and also when pH was raised (pH 3 ~ pH 9). In systems of emulsion stabilized with OSA-${\beta}$-glucan, fat globule size found to decrease with increasing concentration of OSA-${\beta}$-glucan, showing a critical value of about $0.32{\mu}m$ at 0.5 wt%. When the OSA-${\beta}$-glucan emulsions were stored, it was found that fat globule size was increased with storage time and particularly pronounced increase was observed in emulsion with 1% OSA-${\beta}$-glucan, possibly due to depletion flocculation. Results of creaming stability evaluated by light scattering technique showed that it was more stable in emulsions containing smaller fat globule size. Surface load of OSA-${\beta}$-glucan in emulsions increased with increasing concentration of OSA-${\beta}$-glucan, suggesting a multilayer adsorption.

A Comparative Analysis of Kinematics and Kinetics on Forehand Drive in Squash (스쿼시 Forehand 드라이브 동작 시 운동역학적 비교연구)

  • Jin, Young-Wan;Park, Yang-Hee;Park, Jae-Young
    • Korean Journal of Applied Biomechanics
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    • v.17 no.4
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    • pp.17-25
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    • 2007
  • The purpose of the study is to give basic data for the improvement of the skill and to show an exemplary position for squash club members or trainers thru a comparative analysis on the kinematics and kinetics variables on the forehand drive motion in playing squash. The objects of the research are divided into two sections, skilled group(n=8) and unskilled group(n=8). The skilled group is composed of professional players currently working and unskilled group is career of six month, both of lives in B city. In this research, to gather the data 3D motion analysis and test result analysis using force platform was used. The variables are duration, position, segment velocity, segment acceleration and etc. in using force platform. The results are as follows: 1. The duration per phase of the skilled is 0.18sec P1(DS) while that of unskilled is 0.32sec. in P2(FT), the duration of the skilled is 0.29sec, that of unskilled is 0.34sec. Average of the duration of the skilled is 0.48sec, while the unskilled, 0.66sec. 2. Regarding positional movements per event, the unskilled has a relatively higher position in center of gravity, shoulder joint, elbow joint compared with that of the skilled. Generally speaking, positions of the unskilled is higher than the skilled. 3. In segment velocity per event, R-shank, R-upper arm, R-forearm and racket. The skilled is faster than the unskilled. we found a big dig difference in shank. 4. In acceleration per event, there was a big difference in upper-arm and fore-arm of the impact. 5. The skilled group on the force platform shows relatively stable and regular changes while the unskilled shows unstable from the touch down to initial 20% the force value of central support period after the impact moment decreases rapidly and the center of gravity is not moved well. 6. The maximum force value of the skilled is 1019.7N. it is found 19.86% of the total duration. That of the unskilled is 639.2N, it is found 20.67% of total duration.