• 마이크로전자및패키징학회지
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• 제18권3호
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• pp.25-32
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• 2011

초고휘도 비극성 a-GaN LED를 위한 양질의 R-면 사파이어 기판을 제조하기 위해 절단, 연마공정에 대해서 연구하였다. 사파이어는 이방성이 큰 물질로서 R-면과 c-면의 기계적인 특성의 차이에 의해 기판 제조공정 조건이 영향을 받으며, c-면에 비해서 R-면은 이방성 크며 각 결정학적인 면에서의 이방성은 연마공정에는 큰 영향을 미치지 않으나 절단공정에 큰 영향을 미치는 것으로 나타났다. R-면 잉곳의 절단방향이 a-flat에 대해 $45^{\circ}$인 경우에 절단이 가장 효과적으로 이루어졌으며 양호한 절단품질을 얻을 수 있었다. 기계적인 연마가 이루어지는 래핑과 DMP(Diamond mechanical polishing) 공정에서는 c-면 기판과 연마율이 큰 차이가 나타나지 않았으나, 화학반응이 수반되는 CMP(Chemical mechanical polishing) 공정에서는 c-면 기판의 연마율이 R-면 기판의 약 2배 이상 큰 값을 가졌으며, 이는 c-면의 수화반응층 형성에 의한 영향으로 보여진다.

• Tribology and Lubricants
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• 제32권2호
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• pp.44-49
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• 2016

Diamond mechanical polishing (DMP) is a crucial process in a sapphire wafering process to improve flatness and achieve the target thickness by using free abrasives. In a DMP process, material removal rate (MRR) is a key factor to reduce process time and cost. Controlling mechanical parameters, such as velocity and pressure, can increase the MRR in a DMP process. However, there are limitations of using high velocities and pressures for achieving a high MRR owing to their side effects. In this paper, we present the lapping characteristics and improvement of MRR by using a fixed abrasive plate through an experimental study. The change in MRR as a function of velocity and pressure follows Preston's equation. The surface roughness of a wafer decreases as the plate velocity and pressure increases. We observe a sharp decrease in MRR over the lapping time at a high velocity and pressure in the velocity and pressure test. An analysis of surface roughness (Rq and Rpk) indicates that wear of abrasives decreases the MRR sharply. In order to investigate the effect of abrasive wear on the MRR, we utilize a cutting fluid and a rough wafer. The cutting fluid delays the wear of abrasives resulting in improvement of MRR drop. The rough wafer maintains the MRR at a stable rate by self-dressing.

• 한국정보통신학회논문지
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• 제9권4호
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• pp.777-781
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• 2005

저작권의 보호 및 관리는 멀티미디어 콘텐츠의 디지털화에 매우 중요한 선결 과제로 이슈화되고 있다. 이에 관련된 기술들은 명칭은 다르지만 공통적으로 디지털 콘텐츠의 저작권 보호 및 미디어 서비스 전반에 걸친 관리 솔루션의 연구개발을 목표로 하고 있다. 디지털 콘텐츠 기술은 디지털 미디어 시대를 이끌어온 주역인 동시에 콘텐츠의 저작권 문제 등을 이끌어낸 주축이 되기도 했으며, 디지털 멀티미디어 표준의 장점이라고 생각되어온 쉬운 복제 및 유포가 저작권 보호의 커다란 문제점으로 인식되고 있다. 표준안이 마련되지 않은 현 시점에서 서비스 업체나, 시스템 개발 업체들은 각자의 독자적인 솔루션을 개발하여 적용하고 있으며, 문제를 해결하기 위해 국내외 여러 기업 및 연구기관에서는 MPEG-21과 같은 디지털 서비스 전반에 걸친 통합관리 솔루션을 연구개발하고 표준안을 마련하기 위해 세계 각국의 연구기관들이 공동으로 프로젝트를 진행하고 있다. 이에, 본 논문에서는 현재의 국내외 미디어 서비스 현황을 조사 분석하고, 저작권 및 디지털 콘텐츠 보호를 위한 기술인 IPMP(Intellectual Property Management and Protection), DMP(Digital Media Project), ENTHRONE(End-to-end Qos through Integrated Management of Content, Networks and Terminals), DRM(Digital Rights Management)의 기술 개발 현황을 조사 분석한다.

• Archives of Pharmacal Research
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• 제28권8호
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• pp.930-935
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• 2005

We have investigated the effects of relatively high concentration of carbachol (CCh), an agonist of muscarinic acetylcholine receptor (mAChR), on cardiac automaticity in mouse heart. Action potentials from automatically beating right atria of mice were measured with conventional microelectrodes. When atria were treated with $100{\mu}M$ CCh, atrial beating was immediately arrested and diastolic membrane potential (DMP) was depolarized. After exposure of the atria to CCh for $\~4 min$, action potentials were regenerated. The regenerated action potentials had lower frequency and shorter duration when compared with the control. When atria were pre-exposed to pirenzepine $(1{\mu}M)$, an $M_1$ mAChR antagonist, there was complete inhibition of CCh-induced depolarization of DMP and regeneration of action potentials. Pre-exposure to AFDX-116 (11 ({2-[(diethylamino)-methyl]-1-piperidyl}acetyl)-5, 11-dihydro-6H-pyridol[2,3-b][1,4] benzodiazepine-6-one base, $1{\mu}M$), an $M_2$ mAChR antagonist, failed to block CCh-induced arrest of the beating. However, prolonged exposure to CCh elicited gradual depolarization of DMP and slight acceleration in beating rate. Our data indicate that high concentration of CCh depolarizes membrane potential and recovers right atrial automaticity via $M_1$ mAChR, providing functional evidence for the role of $M_1$ mAChR in the atrial myocytes.

• Natural Product Sciences
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• 제15권3호
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• pp.144-150
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• 2009

Gradient centrifugal partition chromatography (GCPC) method was developed and applied to isolate 3,5-dimethoxyphenanthrene-2,7-diol (DMP) and batatasin-I (BA-I) from the dichloromethane soluble extract of Dioscorea opposita. In this method, the lower phase of n-hexane-methanol-water system (HMW, 10 : 9 : 1, v/v) was used as a mobile phase A (MpA) and water was used as a mobile phase B (MpB). This gradient CPC method is comparable to that of reversed-phase HPLC method in that the stationary upper-phase of HMW (10 : 9 : 1 v/v) works as if it were reversed-phase silica gel due to its hydrophobic property, while the lower phase (MpA) and water (MpB) functioned as hydrophilic mobile phases. The initial condition of the mobile phase was 20% MpA/80% MpB and maintained for 150 min to obtain DMP (1.2 mg), and then MpA was increased up to 50% to elute BA-I (1.7 mg). The purities of DMP and BA-I were 94.1% and 98.3% with the recovery yields of 83% and 86%, respectively. Similar results were obtained by linear-gradient CPC. The CPC peak fractions were identified by comparing their retention time to those of authentic samples of DMP and BA-I and their spectroscopic data ($^1$H NMR and $^{13}$C NMR) to those of literature values.

• 한국비블리아학회지
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• 제25권3호
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• pp.165-189
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• 2014

본 연구에서는 미국 연구중심대학도서관에서 최근 구축 운영되고 있는 연구데이터관리(Research Data Management, RDM) 서비스의 구성요소와 웹사이트에서 제공되는 서비스의 내용을 분석하여 그 현황을 조사하였다. 미국 카네기분류에서 제시된 최고연구중심대학(RU/VH) 중 RDM 서비스를 제공하는 31개 대학도서관의 서비스 내용을 분석하였으며, 분석의 기준은 선행연구에서 제시된 서비스의 구성요소 9가지로 (1) DMP 작성지원; (2) 데이터 파일 정리; (3) 데이터 기술; (4) 데이터 저장; (5) 데이터 공유 및 접근; (6) 데이터 보존; (7) 데이터 인용; (8) 데이터관리 교육; (9) 데이터 지적재산권을 포함한다. 분석 결과 대다수의 기관에서 DMP 작성지원서비스를 운영하고 있었으며 절반 이상의 기관에서 데이터 기술과 데이터 보존 및 데이터관리 교육 서비스를 제공하고 있었다. 특히 학문분야별 데이터에 적합한 메타데이터 및 레포지터리로의 안내와 워크숍 또는 개별 컨설팅을 통한 교육에 초점을 맞추고 있음을 확인할 수 있었다. 향후 기관 내 혹은 기관 간 협력에 기반을 둔 RDM 서비스 운영과 서비스 담당자의 지식 및 역량에 대한 논의와 연구가 지속되어야 할 것이다.

• Asian-Australasian Journal of Animal Sciences
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• 제19권12호
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• pp.1742-1748
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• 2006

The experiment was conducted on 264 crossbred Karan-Fries (Holstein Friesian${\times}$Tharparkar) cows, over one year to explore the possibility of using milk urea (MU) concentration and milk protein content to monitor feeding adequacy under farm condition and to investigate the effects of different animal factors and season on MU concentration. Individual noon (1200 to 1300 h) milk samples were collected once in every month and analysed for urea and protein contents. Representative feed samples were also collected on the same day of milk collection and were analysed for CP content. A significant positive association (p<0.01) between MU concentration and milk yield was observed. MU concentrations (mg/dl) were found to be significantly (p<0.01) higher and lower in first lactation (44.8${\pm}$0.7) and in early lactation stage (40.7${\pm}$0.5), respectively. Average MU values were found to be significantly (p<0.01) higher in winter (50.7${\pm}$0.3) and lower in summer (32.9${\pm}$0.6). During the investigation, of the total MU observations, 50.3% were within the range of 30 to 50 mg/dl, 21.4% were <30 mg/dl and only 7.5% were >60 mg/dl. MU concentration was found to be associated significantly (p<0.05) with CP content of forages rather than concentrate. A close positive association (p<0.01) between MU level and daily milk protein (DMP) yield was observed during the investigation. The regression equation, DMP yield (g) = -24.6+33.5 daily milk yield (kg) +0.9 MU (mg/dl) was developed to establish the reference level of DMP yield. The result indicates that the effect of parity and stage of lactation may be ignored while interpreting MU values. However, reference MU values may be standardised separately for high milk yielders as level of milk yield contributes significantly to the variation of MU. The study revealed that the MU values together with DMP yield and milk protein content could be used as a potential non-invasive pointer to monitor feeding adequacy in dairy cows under farm conditions.

• Journal of Microbiology and Biotechnology
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• 제18권4호
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• pp.670-675
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• 2008

A laccase was isolated from the culture filtrate of the basidiomycete Fomitella fraxinea. The enzyme was purified to electrophoretical homogeneity using ammonium sulfate precipitation, anion-exchange chromatography, and gel-filtration chromatography. The enzyme was identified as a monomeric protein with a molecular mass of 47 kDa by sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE) and gel-filtration chromatography, and had an isoelectric point of 3.8. The N-terminal amino acid sequence for the enzyme was ATXSNXKTLAAD, which had a very low similarity to the sequences previously reported for laccases from other basidiomycetes. The optimum pH and temperature for 2,2'-azino-bis(3-ethylbenzothiazoline-6-sulfonate) (ABTS) were 3.0 and $70^{\circ}C$, respectively. The enzyme also showed a much higher level of specific activity for ABTS and 2,6-dimethoxyphenol (DMP), where the $K_m$ values of the enzyme for ABTS and 2,6-DMP were 270 and $426{\mu}M$, respectively, and the $V_{max}$ values were 876 and $433.3{\mu}M/min$, respectively. The laccase activity was completely inhibited by L-cysteine, dithiothreitol (DTT), and sodium azide, significantly inhibited by $Ni^+,\;Mn^{2+}$, and $Ba^{2+}$, and slightly stimulated by $K^+$ and $Ca^{2+}$.

• 한국자동차공학회논문집
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• 제14권3호
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• pp.186-195
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• 2006

In real-time control systems, the traditional timing analysis based on worst-case response-time(WCRT) is too conservative for the firm and soft real-time control systems, which permit the maximum utilization factor greater than one. We suggested a probabilistic analysis method possible to apply the firm and soft real-time control systems under considering dependency relationship between tasks. The proposed technique determines the deadline miss probability(DMP) of each task from computing the average response-time distribution under a fixed-priority scheduling policy. The method improves the predictable ability forthe average performance and the temporal behavior of real-time control systems.

• 미생물학회지
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• 제34권3호
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• pp.115-119
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• 1998

Pseudomonas sp. DJ77로부터 전보에서 클로닝한 pHENX7의 하류방향으로 약 3kb 정도를 포함하는 pYCS500을 클로닝하였다. PYCS500의 제한효소지도를 작성하고 부분적으로 염기서열을 분석한 결과 465 bp의 HindIII-ClaI절편에서 282 bp로 이루어진 하나의 open reading frame(ORF)을 발견하였다. phnM으로 명명된 이 ORF는 93개의 아미노산으로 구성된 polypeptide를 암호화하고 있었으며 계산된 분자량은 10,008 Da이었다. PhnM은 NahT, XylT, DmpQ, AtdS, PhlG, PhhQ, TbuW 등 plant-type ferredoxin 형태의 단백질과 37.7%-53.9%의 상동성을 나타내었으며 이들이 공통적으로 가지고 있는 motif가 일치하였다.