• Title/Summary/Keyword: DF-1

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Comparison of Gangji-hwan-1, 2, 3, 4 and Combination of Gangji-hwan-1 and Gamisoche-hwan in the Reducing Effects of Body Weight in a High Fat Diet-Fed Obese Mice (고지방식이 비만마우스 모델에서 파키스탄산 및 중국산 마황으로 조성된 강지환(降脂丸)-1, 2, 3, 4와 강지환(降脂丸)-1합가미소체환(合加味消滯丸)의 체중감량효과 비교)

  • Yoo, Jae Sang;Ku, Ja Ryong;Yoon, Ki Hyeon;Jo, Ju Heum;Jang, Du Hyon;Jung, Yang Sam;Kim, Jong Hoon;Kim, Byeong Chul;Seok, Hoa Jun;Yoon, Michung;Roh, Jong Seong;Shin, Soon Shik
    • Journal of Korean Medicine for Obesity Research
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    • v.15 no.1
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    • pp.9-23
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    • 2015
  • Objectives: This study was investigated the improvement effects of Pakistani Ephedra herba-containing Gangji-hwan-1, 2, 3 (Di-fatty; DF-1, 2, 3), Chinese Ephedra herba-containing Gangjihwan-4 (DF-4) and combination of DF-1 and Gamisoche-hwan (GSH) on obesity in a high fat diet-fed obese mouse model. Methods: Eight-week-old C57BL/6N mice were divided into seven groups: a normal lean group given a standard diet, an obese control group given a high fat diet, and DF-1, 2, 3, 4, and DF-1+GSH groups given a high fat diet with DF-1, 2, 3, 4 (40, 80, 160, 80 mg/kg), and DF-1+ GSH (80 mg/kg), respectively. After 8 weeks of treatment, body weight gain, feeding efficiency ratio (FER), blood lipid markers, liver histology, and fat weight and histology were examined. Results: Body weight gain was significantly decreased in DF and DF-1+GSH groups compared with control. The extent of decreases was eminent in DF-1+GSH group. FER and circulating concentration of leptin were decreased in DF and DF-1+GSH groups compared with control. Circulating concentrations of triglyceride, glucose and insulin were decreased in DF and DF-1+GSH groups compared with control. The size of adipocytes were decreased by DF and DF-1+GSH groups compared with control, whereas the adipocyte number per unit area was increased by them, suggesting that DF and DF-1+GSH groups decreased the number of large adipocytes. Conclusions: In conclusion, these results suggest that DF and DF-1+GSH groups decrease FER, plasma leptin concentration, blood anti-obesity biomarkers and fat mass, improves body weight gain. In addition, these effects were more effective in DF-1+GSH combination group than in DF-1, 2, 3, 4 groups.

The Effects of Different Feeding Strategies on the Growth of Young Nile tilapia, Oreochromis niloticus L., in a Freshwater Recirculating System during Summer

  • Cho Sung Hwoan;Jo Jae Yoon
    • Fisheries and Aquatic Sciences
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    • v.8 no.1
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    • pp.38-42
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    • 2005
  • We evaluated the effects of different feeding strategies on the growth of young Nile tilapia, Oreochromis niloticus L., in a freshwater recirculating system during summer. Each of twenty fish (Mean body weight$\pm$ SD; 37. 7$\pm$0.10 g) were randomly distributed into each of 24 tanks. Eight treatments were prepared in triplicate. Control fish were hand-fed commercial feed twice daily without starvation. The other seven treatments employed different feeding and starvation strategies ranging from I day starved and 1 day fed (1DS+ 1DF) to 7 days starved to 7 days fed (7DS+7DF). All fish survived to the end of the 44-day feeding trial. The amount of food supplied was highest for the control fish in the control. Food supplied to fish in the 3DS+3DF and 4DS+4DF treatments was significantly lower than that of fish in the 1DS+1DF and 2DS+2DF treatments, but significantly higher than that of fish in the 5DS+5DF, 6DS+6DF and 7DS+7DF treatments. The weight gain of control fish was significantly higher than that of fish in other treatments. Feed efficiency ratio (FER) for fish in the 7DS+7DF treatment was significantly higher than that of fish in the control group, but it did not differ from that of fish in the 1DS+1DF and 2DS+2DF treatments. We concluded that young Nile tilapia raised with different starvation and feeding regimes during the summer in a freshwater recirculating system did not catch up in growth to fish fed daily. However, the enhanced FER of Nile tilapia in the 7DS+ 7DF, 2DS+ 2DF, and 1 DS+ I DF treatments partly explains the compensatory growth of the fish, although their weight gain was relatively low.

Independent Inheritance between df2 gene and ti gene in Soybean

  • Han, Eun-Hui;Sung, Mi-Kyung;Kim, Kyung-Roc;Park, Jung-Soo;Nam, Jin-Woo;Chung, Jong-Il
    • KOREAN JOURNAL OF CROP SCIENCE
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    • v.56 no.1
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    • pp.14-17
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    • 2011
  • Dwarfuess and Kunitz trypsin inhibitor (KTI) protein in soybean is useful traits for basic studies. df2 and ti gene control dwarfness and the expression of Kunitz trypsin inhibitor (KTI) protein in soybean, respectively. The objective of this research was to verify genetic linkage or independent inheritance of df2 and ti loci in soybean. The $F_2$ population was made by cross combination between "Gaechuck#2" (Df2Df2titi genotype, KTI protein absence and a normal growth type) and T210 (df2df2TiTi genotype, a dwarf growth type and KTI protein present). A total of 258 $F_2$ seeds were analyzed for the segregation of KTI protein using SDS-PAGE. And so, 198 $F_2$ plants were recorded for the segregation of dwarfness. The segregation ratio of 3 : 1 for Ti locus (201 Ti_ : 57 titi) and Df2 locus (143 Df2_ : 55 df2df2) was observed. Segregation ratio of 9 : 3 : 3 : 1 (116 Ti_Df2_: 44 Ti_df2df2: 27 titiDf2_: 11 titidf2df2) between df2 gene and ti gene was observed ($x^2$=3.53, P = 0.223). These results showed that df2 gene was inherited independently with the ti gene in soybean.

A Study on the Patient Care Standard (환자간호실무 표준에 관한 연구)

  • Yoon, Suck-Hee;Kang, Chai-Won;Jurn, Mee-Soo;Kim, Yong-Soon;Kim, Moung-Ock;Park, Sung-Ae;Kim, Hye-Ja;Lee, Byung-Sook;Jung, Myun-Sook;Jun, Myung-Hee
    • The Korean Nurse
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    • v.31 no.1
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    • pp.68-87
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    • 1992
  • The purpose of this study is to develop a patient care standard which is the basis of unit based quality assurance. The subjects were 570 nurses of 6 hospitals is Seoul. Patient Care Standards were developed from 3 times of clinical Nurses Association's workshop & the joint meeting of Clinical Nurses Association & the Korean Nurses Academic Socity of Nursing Administration. Respondents were instructed to rate of the 2 types of 5 - point Likert type questionnaire(one is the level of perceived importance, the other is the level of actual performance) Findings of this study were as follows 1. As a results of reliability analysis, each questionnaire ranged from $\alpha$=0.79 to 0.94

    2. The Correlations between the levels of perceived importance & actual performances were ranged from r=.40 to 0.72(P=.00) 3. There were significant differences in the level of percevied importance according to the several variables. $\circled1$ Chemotherapy unit; df=5, F=4.06, P=.000/hospital $\circled2$ Pediatric unit; df=5, F=2.8, P=.02/hospital $\circled3$ OBGY ; df=5, F=4.20, P=.00/hospital $\circled4$ ICU ; df=5, F=2.83, P=.02/hospital df=3, F=5.38, P=.00/age df=3, F=6.22, P=.00/total duration. $\circled5$ GS ; df=3, F=3.37, P=.02/total duration 4. There were significant difference in the level of actual performance according to the several variables. $\circled1$ Chemotherapy unit; df=5, F=2.89, P=.02/hospital df=3, F=3.07, P=.03/age df=3, F=3.61, P=.02/total duration $\circled2$ OBGY ; df=5, F=15.48, P=.00/hospilal df=3, F=7.83, p=.00/total duration $\circled3$ GS ; df=5, F=6.70, P=.00/hospital df=3, F=4.49, P=.01/age df=3, F=5.99, P=.00/total duration $\circled4$ ICU ; df=5, F=2.96, P=.02/hospital df=3, F=4.39, P=.0l/age df=3, F=5.20, P=.00/total duration

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  • Analysis of Various Honeys from Different Sources Using Electronic Nose (다른 밀원에서 기원한 꿀의 전자코 분석)

    • Hong, Eun-Jeung;Park, Sue-Jee;Lee, Hwa-Jung;Lee, Kwang-Geun;Noh, Bong-Soo
      • Food Science of Animal Resources
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      • v.31 no.2
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      • pp.273-279
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      • 2011
    • Various honeys from different sources were analyzed using an electronic nose based on a mass spectrometer. Various honeys were separated with different mixing ratios. Wild honey and artificial honey were blended at ratios of 100:0, 95:5, 90:10, 85:15, 80:20, 75:25, and 70:30, respectively. Data obtained from the electronic nose were used for discriminant function analysis (DFA). The DFA plot indicated a significant separation of honey from different sources. As the concentration of artificial honey increased, the first discriminant function score (DF1) moved from positive to negative (DF1: $r^2$=0.9962, F=490.6; DF2: $r^2$=0.9128, F=19.44). Furthermore, when acacia honey was mixed with artificial honey and separated with the mixing ratios, the DF scores were: DF1: $r^2$=0.9957, F=396.64; DF2: $r^2$=0.9447, F=29.3. When artificial honey was added to wild honey, it was possible to predict the following equation; DF1= -0.106${\times}$(concentration of artificial honey)+0.426 ($r^2$= 0.96). For acacia honey, the DF1= -0.112${\times}$(concentration of artificial honey)+0.434 ($r^2$=0.968).

    Estimation of Dietary Fiber Intake of College Students (대학생의 식이섬유 섭취에 관한 연구)

    • 이혜성
      • Journal of Nutrition and Health
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      • v.24 no.6
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      • pp.534-546
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      • 1991
    • Three-day dietary records data from 237 college students(male 65, female 172) were used as the basis to estimate total dietary fiber(DF) intake of Korean adults & to investigate the major food sources of fiber. Mean daily DF intake of the subjects was 15.2$\pm$3.7g range being 7.5-34g When related to energy intake women consume more DF(7.7$\pm$1.5/1000kcal) than men(6.8$\pm$1.7g/1000kcal) Mean daily crude fiber(CF) intake of the subjects was 6.2$\pm$2.4g The mean DF:CF ratio for the subjects was 2.5$\pm$0.5 indicating that DF intake is 2-3 times of CF intakes The intakes of the two measures of fiber were highly correlated(r=0.791) The major food sources for DF in Korean are vegetables cereals and fruits and 14.3% respectively In comparision with limited international data on the DF intake by adults DF intake by the subjects was similar to those of developed countries. Present study indicates that DF intakes of the subjects are considerably lower than recommended level and they need to consume more DF than the present level.

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    Validation of Serum Aminotransferases Levels to Define Severe Dengue Fever in Children

    • Srivastava, Geetika;Chhavi, Nanda;Goel, Amit
      • Pediatric Gastroenterology, Hepatology & Nutrition
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      • v.21 no.4
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      • pp.289-296
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      • 2018
    • Purpose: We aimed to study the pattern of liver-injury in children with dengue fever (DF) and validate serum aminotransferase ${\geq}1,000IU/L$ as a marker of severe DF. Methods: Children admitted with DF were included. DF was defined by presence of clinical criteria and positive serological or antigen tests in absence of other etiology. DF severity was graded as dengue without or with warning signs and severe dengue. Liver-injury was defined as alanine aminotransferase (ALT) more than twice the upper limit of normal (boys, 30 IU/L; girls, 21 IU/L). Results: Of 372 children with DF, 144 (38.7%) had liver-injury. Risk of liver-injury and aminotransferase levels increased with DF severity (p<0.001). Recommended ALT and aspartate aminotransferase (AST) cut-off at ${\geq}1,000IU/L$ had sensitivity 4.8% (5/105), specificity 99.3% (265/267) for detection of severe DF. In children with ALT and AST <1,000 IU/L (n=365), the area under receiver operating curves for prediction for severe DF, were 0.651 (95% confidence interval [CI], 0.588-0.714; p<0.001) for ALT and 0.647 (95% CI, 0.582-0.712; p<0.001) for AST. Serum ALT at 376 IU/L and AST at 635 IU/L had sensitivity and specificity comparable to ${\geq}1,000IU/L$ for defining severe DF. Conclusion: Liver-injury is common in DF. The ALT and AST levels increase with DF severity. ALT and AST levels of ${\geq}1,000IU/L$ could be lowered to 376 IU/L and 635 IU/L respectively for defining severe DF.

    Annual Changes in the Estimated Dietary Fiber Intake of Korean during $1991{\sim}2001$ (한국인 식이섬유 섭취 상태의 연차적 추이 $(1991{\sim}2001)$)

    • Lee, Hye-Jung;Kim, Young-Ah;Lee, Hye-Sung
      • Journal of Nutrition and Health
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      • v.39 no.6
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      • pp.549-559
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      • 2006
    • The present study determined the estimated dietary fiber (DF) intake per capita of Korean from 1991 to 2001 and analyzed the major food sources of dietary fiber for Korean using the data on per capita consumption of each food reported in the Korean National (Health and) Nutrition Survey Reports and the recently established DF database by the Korean Nutrition Society. The estimated mean daily DF intakes of Korean during the last 11 years $(1991{\sim}2001)$ were in the range of $19.25{\sim}21.22\;g\;or\;9.97{\sim}11.99\;g/1,000\;kcal$ with a small range of fluctuations. As of 2001, average DF intake per capita of Korean was estimated as 20.92 g or 10.59 g/1,000 kcal. The average DF intake level was under the Adequate Intake for DF (12 g per 1,000 kcal) of the Dietary Reference Intakes (DRIs) for Koreans established in 2005. The level of DF intake was relatively lower in small city residents compared to the large city or rural area. The top two major food group sources of DF for Korean were vegetables and cereals, in addition, legumes, fruits, seaweeds and seasonings were included among top five food groups. The ratio of DF intake from fruits was gradually increased but the ratio from legumes was steadily decreased during the last 11 years. The mostly contributed single foods for DF intakes of Korean were Kimchi and rice regardless of year and area. Percentage of DF intake from top ten single foods was continuously decreased from 65% in 1991 to 51 % in 2001. The results of this study revealed that DF intakes of Korean as of 2001 is insufficient compared to the Adequate Intake for DF for Korean and the source of fiber in Korean diet has been more various. Therefore the beneficial health effects of DF and the increased consumption of DF from a variety of food sources should be continuously emphasized through the nutritional education.

    Discrimination of Grading Pungency for Red Peppers Spice Using Electronic Nose Based on Mass Spectrometer (고춧가루의 매운 맛 등급화를 위한 Mass Spectrometer를 바탕으로 한 전자코 분석)

    • Kang, Jin Hee;Son, Hee-Jin;Hong, Eun-Jeung;Noh, Bong-Soo
      • Food Engineering Progress
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      • v.14 no.1
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      • pp.35-40
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      • 2010
    • Electronic nose (E-nose) was assessed for grading pungency of powdered red pepper. Complex pretreatments are not required for flavor analysis unlike HPLC or Scoville tests. Mild and pungent taste of powdered red pepper were mixed at various concentrations of 0, 25, 50, 75, and 100%. Those were analyzed using mass spectrometer-based E-nose. Discriminant function analysis (DFA) was conducted on E-nose data. The $R^{2}$ and F-value of dicriminant function first score (DF1) were 0.9946 and 355.65, respectively, when the samples were separated by a relative degree of pungent taste. DF1 value decreased with increasing the amount of powdered red pepper with a pungent taste. It is similar to the increase in the concentration of capsaicin. Increasing the amount of red pepper powder, dicriminant function second score (DF2) values were moved from the negative position into the positive position. The $R^{2}$ and F-value of DF1 were 0.9890, 165.17 and DF2 were 0.9219, 21.64. Also, the results by MS based E-nose agreed to that by HPLC. There is the potential to grade pungent taste of powdered red pepper using the E-nose.

    Grapefruit Seed Extract (DF-100) Treatment of Poultry to Reduce Attached Salmonella

    • Mike F. Slavik;Kim, Jeong-Weon;Phil L. Matsler;Hong Wang
      • Journal of Food Hygiene and Safety
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      • v.11 no.1
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      • pp.7-10
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      • 1996
    • Chicken skins or carcasses inoculated with Salmonella typhimurium were exposed to 0.1 or 0.5% grapefruit seed extracts (DF-100) for 1 or 3 min to evaluate antibacterial activity of DF-100 and its possible application in proultry processing. The numbers of live salmonellae on chicken skins were reduced by 0.8-1.2 logs/cm2 with 0.5% DF-100. Dipping chicken carcasses into 0.5% DF-100 for 3 min reduced salmonelae by 4.3 logs/carcass. Scanning electron microscopy showed that DF-100 killed the cells attached but did not detach cells from the skin. No odor or changes in the color of chicken skin were detected after DF-100 treatment.

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