• Feed Journal
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• v.4 no.8 s.36
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• pp.73-77
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• 2006

농업ㆍ농촌이 우리에게 어떤 의미를 지니는가. 흔히 산업의 한 분야로 분류되지만, 문명과 함께 태동해 자연과 소통하며 이루어내는 인류의 끝없는 도전, 생명과 직결되는 분야기에 더 많은 관심을 요구한다면 지나친 편애일까. '농업ㆍ농촌이 무엇인가'라는 근본적인 질문을 던져보는 행사가 펼쳐져 농축산계의 관심이 모아지고 있다. 농촌진흥청은 오는 8월 30일 부터 9월 3일까지 5일간 청내에서 농업관련 기관과 단체 및 학계 등이 공동으로 참여하는 '한국농업 근현대화 100년 기념사업'을 개최한다. 특히 오랜 농민단체 생활을 통해 농정 관련 현장 경험이 풍브, 지난 2월 농축산계의 뜨거운 관심 속에 부임한 김인식 농촌진흥청장은 "이번 사업을 우리 농업과 농촌이 재도약할 수 있는 발판을 다지는 계기로 삼을 것"이라는 포부를 밝혔다. 김 청장은 경상대학교 축산학과를 졸업한 1992년부터 전국농민단체협의회 사무총장. 한국낙농육우협회 전무, WTO 국민연대 사무총장에 이어 정책실장실 농어촌 비서관 등을 역임, 효율적인 대외협상과 함께 농진청의 농업연구와 지도사업에 새로운 방향을 제시할 것으로 기대되고 있다. FTA, DDA협상 등 개방화의 물결 속에 농촌이 어느 때보다 어려움을 겪고 있는 시점에 피드저널 유동준 발행인 겸 편집인은 7월12일 농촌진흥청 청장실에서 김 청장을 만나 '한국농업 근현대화 100년 기념사업 추진 방향과 농어축산업 발전'을 주제로 대담을 나눴다.

• Elastomers and Composites
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• v.50 no.4
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• pp.265-273
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• 2015

In this work, the emulsified asphalt with high phase stability and storage stability was prepared by using phase inversion emulsification and the surfactant mixed with cationic and nonionic surfactants. It was found that the asphalt together with Span 20, nonionic surfactant and DDA (Dimethyl Dodecyl Amine), cationic surfactant showed the most stable phase. The phase stability of the emulsified asphalt, therefore, was investigated through the particle size with mixed surfactant content, rheology behavior and Zeta potential value; the particle size decreased with the increase of the mixed surfactant content but the viscosity increased. The shear thinning behaviors and the Zeta potential value with 50 mV~60 mV were shown, which was found to be considered stable. In addition, SBR latex(Styrene-butadiene-rubber) and water dispersed Epoxy (EPD) were used to enhance the physical properties of the emulsified asphalt. The swelling and adhesion features of the emulsified asphalt were also studied with $CaCO_3$, Silica, and Montmorillonite (MMT). It was shown that the addition of SBR latex and MMT can be another way to improve the physical properties of the emulsified asphalt in that the lowest swelling feature was found.

• Proceedings of the Korea Water Resources Association Conference
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• 2017.05a
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• pp.271-271
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• 2017

상수관망 수리해석 기법은 절점의 사용량 및 누수량을 기지의 값으로 고려하여 총 수요량이 모두 공급될 수 있다고 가정하여 해석하는 수요기반해석(Demand Driven Analysis, DDA)과 사용량과 누수량은 절점 압력수두에 의해 달라질 수 있어, 공급가능량 및 누수량과 절점의 압력수두 모두를 미지수로 고려하여 해석하는 수압기반해석(Pressure Driven Analysis, PDA)으로 구분될 수 있다. 본 연구에서는 수압기반사용량 모의(Pressure Dependent Demand, PDD)와 수압기반누수량 모의(Pressure Dependent Leakage, PDL)기능이 모두 구현되고, 다양한 시나리오 분석이 가능한 소프트웨어(SW)인 K-NRisk를 개발하였다. K-NRisk는 2016년 7월에 공개된 상수관망 해석범용모형인 EPANET3 소스코드 기반으로 개량 개발되었으며, 기존 EPANET2와 비교하였을 경우 사용자 편의성 증대를 위한 입출력 기능 및 SW 활용도 제고를 위한 대표업무분석 기능이 신규 개발, 강화되었다. 개발된 SW를 관망정비 및 공급안정성 확보 목적을 위한 수리해석 시 적용하여 그 결과를 분석하였다. 적용결과 기존 수요기반해석이 가지고 있는 한계점을 보완하고, 실제업무 시 활용가능함을 확인하였다.

• The Journal of Fisheries Business Administration
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• v.37 no.3 s.72
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• pp.65-83
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• 2006

This study is to obtain the order of the sensitivity of importing marine products with regard to non - economic aspects of considerations under the free - trade. Three criteria are extracted considering various aspects of Korean fishery society. They are the socio - economic, resource - environmental, and policy - appropriateness criterion. The Analytic Hierachy Process(AHP) is used to obtain the estimates of weights among these criteria. First of all, the weights between economic and non - economic in the first hierachy of sensitivity criteria turn out to be 83.3% and 16.7%. Second, the weights among three criteria in the non - economic aspect, the second hierachy, are following that the socio - economic criterion is 19.6%, resource - environmental 31.1%, and policy - appropriateness 49.3% respectively. 47 selected fishes are evaluated based on these three non - economic criteria using 9- point scales. The over - all order of sensitivity is a croaker, hairtail, flatfish, sea breams, and so forth in descending order. The least sensitive fish turns out to be an angler. In addition to the over - all order, the sensitivity based on the three specific non - economic aspects is also investigated. The most sensitive fish in terms of the socio - economic criterion is an hairtail while the least one is a filefish. The most sensitive fish in terms of the resource - environmental criterion is an abalone while the least one is an angler. Finally, the most sensitive fish in terms of the policy - appropriateness is a mackerel while the least one is a small octopus.

• Health Policy and Management
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• v.13 no.3
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• pp.52-70
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• 2003

The rate of conversion to Medical-juridical-persons' ownership of medical institutions has increased rapidly since its start in 1970s in Korea. The most sensitive issue to introduce for-profit medical institutions, ignited particularly by the WTO/DDA negotiations, has sparked considerable debate, stemming largely from conflicting views on the theoretical effects of ownership status on organizational behavior. This study surveyed health-related experts' opinions on allowing for for-profit-firms-owned medical institutions. Some fear that the obligation to maximize the share-holders' return on their investment will cause the medical institutions to eliminate necessary but less lucrative services. They may easily fall under more pressure to generate income, and respond more aggressively than not-for-profit medical institutions to financial pressures. Advocates of for-profit ownership of medical institutions argue that greater responsiveness to the demands of the marketplace will lead to larger investment, higher quality and lower costs to consumers. Referring to both foreign countries' experience and domestic experts' opinions, this study suggests for reform of the current Korean Medical-Juridical-Person(MJP) System. Introduction of so-called “Capital-investment” MJPs is recommended where the properties left in case of their dissolution can be distributed to original investors according to the procedures stipulated in their statutes. However, their annual profits are not allowed to be allocated to investors, but should be reinvested for their medical institutions, as is the case in current MJPs. Their legal aspects are also reviewed in this study.

• Korean Journal of Organic Agriculture
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• v.27 no.3
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• pp.271-288
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• 2019

It has continuously promoted to scale up the agricultural management body in order to cope with the market-opening pressure such as the UR negotiation, the DDA negotiation, and more conclusions of FTAs and to enhance the competitiveness of our agriculture. This study evaluated the factors associated with production organization participation centered on environmentally-friendly agriculture farmers in order to improve the production efficiency of environmentally-friendly agriculture in the aspect of production. In order to achieve this objective, this study evaluated the factors that contributed to participating in an organization using the bivariate probit model focusing on environmentally-friendly agriculture farmers in Chungnam. This study examined the validity and reliability of the study model through exploratory factor analysis. The results of factor analyses identified four factors: "distribution", "production", "organization operation", and "social capital". The results of the bivariate probit model showed that distribution significantly affected production activities and distribution, organization operation, agricultural income, and gender significantly influenced sale activities. Environmentally-friendly production organization had not been able to provide the productive support that was needed for local farmers to produce environmentally-friendly agricultural products in a region. Additionally, farming education did not provide the information needed by the farmers. Although producers had a network within a production organization, it was operated mainly for administrators. Therefore, participants felt somewhat lacking. This study identified the level of organization of producer organizations in Chungnam area, where environmentally-friendly agriculture is well activated. This study suggested implications for future production organization participation by evaluating factors affecting participation quantitatively.

• The Journal of Fisheries Business Administration
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• v.36 no.3 s.69
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• pp.65-88
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• 2005

The fisheries industry has been changed drastically during the so - called Golden Growth Era of Korea. Recently, WTO/DDA agenda drove industries out of their safe refuges toward infinite competitions in the world. This paper aims at finding out distinguished features in the structural changes of fisheries since 70s. Furthermore, policy implications are investigated in order for the fisheries to survive in the outdoors. The paper consists of the following sections. First, we consider why and for what the structural change of fisheries in historical perspective should be investigated. And we introduce how we can approach to the goal in various aspects in the second section. In the third section, we examine the historical change of Korean fisheries in respect of national economy, resource allocation mechanism, industrial structure, and fisheries society. In the fourth section, we extract the development steps in fisheries from the periodic characteristics, using various methods of the above approaches. And we deduce the next step for Korean fisheries in the future. Finally, we conclude that there needs some turning point of fisheries policies in Korea, striving to foster the fisheries industry in the future. As results of empirical analysis in this paper, we find that fisheries industry in Korea has experienced some momentous changes during 30 years, using I/O data of B.O.K. The weight of fisheries sector in the whole economy of Korea increased during early 70s, initially leading the national economy to export - oriented engine for growth. But fisheries sector has shrunk rapidly since late 70s. Almost resources in Korea were allocated to expanding manufacturing industries. Further, fisheries industry has encountered perfect international competitions since the late 90s. This paper draws that fisheries industry in Korea will jump across to next step of qualitative growth in the future. Therefore, we recommend that the policies should be focused on enhancing the industrial competitiveness, switching quantitative growth to qualitative advance in fisheries.

• IMMUNE NETWORK
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• v.23 no.2
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• pp.16.1-16.19
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• 2023

Bacillus Calmette-Guerin (BCG) vaccine is the only licensed vaccine for tuberculosis (TB) prevention. Previously, our group demonstrated the vaccine potential of Rv0351 and Rv3628 against Mycobacterium tuberculosis (Mtb) infection by directing Th1-biased CD4⁺ T cells co-expressing IFN-γ, TNF-α, and IL-2 in the lungs. Here, we assessed immunogenicity and vaccine potential of the combined Ags (Rv0351/Rv3628) formulated in different adjuvants as subunit booster in BCG-primed mice against hypervirulent clinical Mtb strain K (Mtb K). Compared to BCG-only or subunit-only vaccine, BCG prime and subunit boost regimen exhibited significantly enhanced Th1 response. Next, we evaluated the immunogenicity to the combined Ags when formulated with four different types of monophosphoryl lipid A (MPL)-based adjuvants: 1) dimethyldioctadecylammonium bromide (DDA), MPL, and trehalose dicorynomycolate (TDM) in liposome form (DMT), 2) MPL and Poly I:C in liposome form (MP), 3) MPL, Poly I:C, and QS21 in liposome form (MPQ), and 4) MPL and Poly I:C in squalene emulsion form (MPS). MPQ and MPS displayed greater adjuvancity in Th1 induction than DMT or MP did. Especially, BCG prime and subunit-MPS boost regimen significantly reduced the bacterial loads and pulmonary inflammation against Mtb K infection when compared to BCG-only vaccine at a chronic stage of TB disease. Collectively, our findings highlighted the importance of adjuvant components and formulation to induce the enhanced protection with an optimal Th1 response.

• Journal of Life Science
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• v.26 no.3
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• pp.376-386
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• 2016

Apoptosis induction has been proposed as an efficient mechanism by which malignant tumor cells can be removed following chemotherapy. The intrinsic mitochondria-dependent apoptotic pathway is frequently implicated in chemotherapy-induced tumor cell apoptosis. Since DNA-damaging agent (DDA)-induced apoptosis is mainly regulated by the tumor suppressor protein p53, and since more than half of clinical cancers possess inactive p53 mutants, microtubule-damaging agents (MDAs), of which apoptotic effect is mainly exerted via p53-independent routes, can be promising choice for cancer chemotherapy. Recently, we found that the apoptotic signaling pathway induced by MDAs (nocodazole, 17α-estradiol, or 2-methoxyestradiol) commonly proceeded through mitotic spindle defect-mediated prometaphase arrest, prolonged Cdk1 activation, and subsequent phosphorylation of Bcl-2, Mcl-1, and Bim in human acute leukemia Jurkat T cells. These microtubule damage-mediated alterations could render the cellular context susceptible to the onset of mitochondria-dependent apoptosis by triggering Bak activation, Δψm loss, and resultant caspase cascade activation. In contrast, when the MDA-induced Bak activation was inhibited by overexpression of anti-apoptotic Bcl-2 family proteins (Bcl-2 or Bcl-xL), the cells in prometaphase arrest failed to induce apoptosis, and instead underwent mitotic slippage and endoreduplication cycle, leading to formation of populations with 8N and 16N DNA content. These data indicate that cellular apoptogenic mechanism is critical for preventing polyploid formation following MDA treatment. Since the formation of polyploid cells, which are genetically unstable, may cause acquisition of therapy resistance and disease relapse, there is a growing interest in developing new combination chemotherapies to prevent polyploidization in tumors after MDA treatment.

• The Journal of Industrial Distribution & Business
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• v.1 no.1
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• pp.13-21
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• 2010

Since Korea establish diplomatic ties with China in 1992, korea and China have had rapid progress in most of field as politic, economy, society and culture through basing on cultural commonality and geographical adjacency. Especially, China is the biggest trading partner to korea, and also Korea is third-biggest trading country to China. They become strategic cooperating relation in 2008. Currently, in terms of international trade relation, WTO/DDA negotiation is proceeding in difficulty, but FTA has been growing and extending in the world, and the two country, china and korea, have been competitively trying wide and active FTA negotiation promotion. After Financial crisis in 1997, according to the requirement of local economic cooperation, China has shown the interest to several countries since the conclusion of FTA treaty with ASEAN in 2005. China also makes the active afford to conclude FTA with Korea. Last May 28th, this was mentioned in the meeting between president Lee and Premier Wen Jiabao, so it is anticipated that the negotiation for FTA will be started in the near future. There are many political suggestions and concerns in terms of way of negotiation korea would choose. Some economist said that "'Continuous FTA aimed at long-term protocol should be promoted between korea and China and negotiated includingly'" However, this research claims that commodity exchange, service, and investment areas should be included and it has to be comprehensive package settlement style in negotiation. This research has found out the characteristics of China's negotiation and implications through the China's existed FTA negotiation examples. Currently, China has taken Continuous or a phase-negotiation method to ASEAN, Pakistan, Chile and some other developing country and to advanced countries like New Zealand or Singapore, comprehensive package settlement method is used in FTA negotiation. In consider of the FTA negotiation between Korea and China, Korea has some problems in the commodity change area in agriculture maket's opening. While, for china, the issues would happen in service trade area, especially when encountering finance and communication industries are opened, China's economy could be exposed to some risk. In result, Korea should expand its negotiation range from commodity trade to service trade, in order to exchange both issues, then the negotiation will be concluded more easily. In other word, for FTA, korea should follow comprehensive package settlement way that is similar to New zealand and Singapore case. Through this kind of method, Korea can expect effect of creating trade, conversion of it and preoccupancy of service field in china's market against the advanced countries like Usa, Europe and Japan. Also, to have a successful FTA negotiation, korea should find out china's policy for FTA negotiation. With this information, korea will be able to suggest the way to make a profit. Systematic analysis and comparison about previous negotiation cases of china are needed before the negotiation begin.