• Molecules and Cells
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• 제46권12호
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• pp.746-756
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• 2023

A recent study revealed that the loss of Deup1 expression does not affect either centriole amplification or multicilia formation. Therefore, the deuterosome per se is not a platform for amplification of centrioles. In this study, we examine whether gain-of-function of Deup1 affects the development of multiciliated ependymal cells. Our time-lapse study reveals that deuterosomes with an average diameter of 300 nm have two different fates during ependymal differentiation. In the first instance, deuterosomes are scattered and gradually disappear as cells become multiciliated. In the second instance, deuterosomes self-organize into a larger aggregate, called a deuterosome cluster (DC). Unlike scattered deuterosomes, DCs possess centriole components primarily within their large structure. A characteristic of DC-containing cells is that they tend to become primary ciliated rather than multiciliated. Our in utero electroporation study shows that DCs in ependymal tissue are mostly observed at early postnatal stages, but are scarce at late postnatal stages, suggesting the presence of DC antagonists within the differentiating cells. Importantly, from our bead flow assay, ectopic expression of Deup1 significantly impairs cerebrospinal fluid flow. Furthermore, we show that expression of mouse Deup1 in Xenopus embryos has an inhibitory effect on differentiation of multiciliated cells in the epidermis. Taken together, we conclude that the DC formation of Deup1 in multiciliated cells inhibits production of multiple centrioles.

• Journal of electromagnetic engineering and science
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• 제12권4호
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• pp.227-233
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• 2012

This paper describes a novel and compact biosensing platform using an RF active system. The proposed sensing system is based on the oscillation frequency deviation due to the biomolecular binding mechanism on a resonator. The impedance variation of the resonator, which is caused by a specific biomolecular interaction results in a corresponding change in the oscillation frequency of the oscillator so that this change is used for the discrimination of the biomolecular binding, along with concentration variation. Also, a Surface Acoustic Wave (SAW) filter is utilized in order to enhance the biosensing performance of our system. Because the oscillator operates at the skirt frequency range of the SAW filter, a small amount of oscillation frequency deviation is transformed into a large variation in the output amplitude. Next, a power detector is used to detect the amplitude variation and convert it to DC voltage. It was also found that the frequency response of the biosensing system changes linearly with three streptavidin concentrations. Therefore, we expect that the proposed RF biosensing system can be applied to bio/medical applications capable of detecting a nano-sized biomolecular interaction.

• 전기학회논문지
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• 제63권7호
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• pp.934-939
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• 2014

The daily recording of basal body temperature is the most useful method of determining the term of ovulation by resolving the rise in temperature. To support this aim, Graphical User Interface (GUI) system is designed and implemented to visualize the basal body temperature variations on daily basis by using android platform smartphone with programming multi-thread Java modules. To estimate the occurrence of ovulation cycle, a new method of analyzing the low-frequency features including a DC level and the second largest peak in frequency spectrum domain is proposed with interpreting the prominent features into the average basal-body temperature variations and a menstrual cycle.

• 전기학회논문지
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• 제67권11호
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• pp.1555-1561
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• 2018

Tracking and detecting targets by the millimeter wave seeker is affected by movement of platform. Stabilization equipments use an inertial sensor to compensate for disturbance of stabilizing gimbal or platform. In the direct line of sight stabilization system, an inertial sensor is mounted on inner gimbal to compensate the disturbance directly, so the performance is excellent and the implementation method is simple. However gimbal design requires somewhat larger volume. Since an inertial sensor is mounted on gimbal base in the indirect line of sight stabilization system, additional space of gimbal is not required for the gimbal design. However, this method does not directly compensate for the disturbance of the line of sight stabilization axis, which can degrade performance. In order to perform the tracking performance, two methods are analyzed for line of sight stabilization performance based on direct and indirect of a 2-axis gimbaled servo system for millimeter wave seeker in this study. The simulation and experimental results validate the performance comparison of two methods.

• 한국정보통신학회논문지
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• 제14권9호
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• pp.1965-1971
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• 2010

선박 추진제어플랫폼은 안전한 항해를 위한 추진기관으로 사용되는 선박주기엔진의 원격운전 및 제어를 담당하는 시스템이다. 본 시스템은 안전하고 신뢰성 있는 운항을 보장하는 시스템이며, 원격제어 기술이 요구되는 시스템이다. 본 연구에서는 해당 시스템의 국산화를 위한 연구의 일환으로서 선박 추진제어시스템의 속도전달장치의 구현에 대해 연구하며, 시스템 분석과 설계 및 구현을 통해 해당 분야의 노하우와 원천기술을 확보하고 추후 추진 제어플랫폼의 통합화를 위한 기반기술을 확보하고자 한다.

• 전기학회논문지
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• 제61권6호
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• pp.865-871
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• 2012

In this study, ambulatory electrocardiogram(ECG) signal and the rhythms of heart beats are visualized in terms of R-R intervals and Heart Rate Variability(HRV) in the environment of an android plaform. With this aim, Graphical User Interface(GUI) is implemented by executing multi-thread Java programming modules including ECG, heart-beats, tachogram and visualization unit. ECG signals are acquired in an android device by receiving the data from ambulatory ECG sensory system. Finite Impulse Response(FIR) filters are implemented to eliminate the baseline wandering noises contained in the ambulatory signals and DC-offset level in R-R interval data. With simulating the normal or stress emotional state of a subject, we can find the fact that HRV can be successfully estimated and visualized in an android smart phone platform.

• Journal of Power Electronics
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• 제16권4호
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• pp.1306-1315
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• 2016

Modern power systems driven by high-power converters have become inevitable in view of the ever increasing demand for electric power. The total power loss can be reduced by limiting the switching losses in such power converters; increased power efficiency can thus be achieved. A reduced switching frequency that is less than a few hundreds of hertz is applied to power converters that produce output waveforms with high distortion. Selective harmonic elimination pulse width modulation (SHEPWM) is an optimized low switching frequency pulse width modulation method that is based on offline estimation. This method can pre-program the harmonic profile of the output waveform over a range of modulation indices to eliminate low-order harmonics. In this paper, a SHEPWM scheme for three-phase three-leg neutral point clamped inverter is proposed. Aside from eliminating the selected harmonics, the DC capacitor voltages at the DC bus are also balanced because of the symmetrical pulse pattern over a quarter cycle of the period. The technique utilized in the estimation of switching angles involves the firefly algorithm (FA). Compared with other techniques, FA is more robust and entails less computation time. Simulation in the MATLAB/SIMULINK environment and experimental verification in the very large scale integration platform with Spartan 6A DSP are performed to prove the validity of the proposed technique.

• 한국산업정보학회논문지
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• 제19권1호
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• pp.31-41
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• 2014

정지궤도위성은 다수의 탑재체를 하나의 위성체 플랫폼에 탑재하고 2010년 6월 26일에 발사되었다. 전력계는 태양 및 식 기간 상태에서 완전 조절 $50V_{DC}$ 전력 버스를 제공한다. 위성에서 요구되는 전력은 태양전지 배열기 윙에서 생성되며, 에너지는 192.5Ah 용량의 리튬-이온 배터리에 저장된다. 본 논문은 전력계의 성능 평가를 향후 정지궤도위성 설계에 활용하기 위해 전력계의 중요 설계 변수들을 선정하고, 지상에서 시험 결과와 궤도상에서 운영 결과를 비교 분석하였다. 설계로부터 궤도상에서 운영 결과까지의 성능 평가를 통해 전력계는 중요한 성능감소 없이 정상적으로 동작되고 있음을 입증하였다.

• 한국인공지능학회지
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• 제11권3호
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• pp.17-22
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• 2023

In this paper, we propose a black ice detection system using Convolutional Neural Networks (CNNs). Black ice poses a serious threat to road safety, particularly during winter conditions. To overcome this problem, we introduce a CNN-based architecture for real-time black ice detection with an encoder-decoder network, specifically designed for real-time black ice detection using thermal images. To train the network, we establish a specialized experimental platform to capture thermal images of various black ice formations on diverse road surfaces, including cement and asphalt. This enables us to curate a comprehensive dataset of thermal road black ice images for a training and evaluation purpose. Additionally, in order to enhance the accuracy of black ice detection, we propose a multi-scale dilation convolution feature fusion (MsDC-FF) technique. This proposed technique dynamically adjusts the dilation ratios based on the input image's resolution, improving the network's ability to capture fine-grained details. Experimental results demonstrate the superior performance of our proposed network model compared to conventional image segmentation models. Our model achieved an mIoU of 95.93%, while LinkNet achieved an mIoU of 95.39%. Therefore, it is concluded that the proposed model in this paper could offer a promising solution for real-time black ice detection, thereby enhancing road safety during winter conditions.

• Journal of Power Electronics
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• 제16권4호
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• pp.1455-1468
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• 2016

This paper presents a grid-connected dual stator-winding induction generator (DWIG) wind power system suitable for wide wind speed ranges. The parallel connection via a unidirectional diode between dc buses of both stator-winding sides is employed in this DWIG system, which can output a high dc voltage over wide wind speed ranges. Grid-connected inverters (GCIs) do not require booster converters; hence, the efficiency of wind energy utilization increases, and the hardware topology and control strategy of GCIs are simplified. In view of the particularities of the parallel topology and the adopted generator control strategy, we propose a novel excitation-capacitor optimization solution to reduce the volume and weight of the static excitation controller. When this excitation-capacitor optimization is carried out, the maximum power tracking problem is also considered. All the problems are resolved with the combined control of the DWIG and GCI. Experimental results on the platform of a 37 kW/600 V prototype show that the proposed DWIG wind power system can output a constant dc voltage over wide rotor speed ranges for grid-connected operations and that the proposed excitation optimization scheme is effective.