• Journal of Ginseng Research
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• v.15 no.3
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• pp.183-187
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• 1991

Effect of ginseng hairy and native roots on body absorption, fecal and urinary excretion of Ingested radiostrontium were investigated in the mouse(NIH-strain, male) treated with or without pre-feeding of each ginseng soluble fraction. The test groups were fed with basic diet supplemented with 1% each ginseng soluble fraction for 7 darts before the radiostrontium were administered by intragastric intubation. In the groups of treated with soluble fraction from ginseng hairy roots, the radioactivities of fecal and urinary excretion increased about 15% over than that of control groups and the whole body retention were about 38%. In the groups of treated with soluble fraction from native ginseng roots, the radioactivities of fecal and urinary excretion increased about 25% over than that of control groups and the whole body retention were about 28%. Also, the levels of radiostrontium accumulation retained significantly the higher percent in skeletons than in other organs.

• Journal of the Korean Home Economics Association
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• v.38 no.5
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• pp.79-90
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• 2000

The purpose of this research is to offer basic data for the study of men's suit by investigating the preference of design and form for men's suits. For data collection, a questionnaire was composed stymie of suits, form of lapel and vent of suits etc‥‥ The subjects of this research were male aged 20-59 and resided in Seoul and the capital region. The results of the research are summarized as the following: 1. Most men tend to prefer a set of suits rather than combination and formal style rather than casual or character style. And most of men like a little enough fittiness of suits. 2. Most men tend to prefer single-breasted jacket rather than double-breasted one. they also tend to prefer notched lapel and no vent jacket, especially men who work in sale, office and an independent enterprise. 3. Men who aged 20-40 tend to prefer classical pants, and one who aged 50 like wide pants. They also tend to prefer pants with pleats rather than one with darts. 4. Most men tend to prefer plain cloth rather than check, stripe pattem, and they tend to select blue and black color as their suits.

• ETRI Journal
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• v.33 no.1
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• pp.89-99
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• 2011

We construct surfaces with darts, creases, and corners by blending different types of local geometries. We also render these surfaces efficiently using programmable graphics hardware. Points on the blending surface are evaluated using simplified computation which can easily be performed on a graphics processing unit. Results show an eighteen-fold to twenty-fold increase in rendering speed over a CPU version. We also demonstrate how these surfaces can be trimmed using textures.

• Proceedings of the KSR Conference
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• 2010.06a
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• pp.249-255
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• 2010

Ballasted track is under the circumstance of repetition of deterioration and recovery. Track deterioration is presented as track irregularity or settlement, and dynamic force subjected to track is one of major cause of the deterioration. The dynamic force is determined from the dynamic interaction between track and vehicle. Rail-pad stiffness is one of the factor affects track dynamic property. In this study, the relationship between rail-pad stiffness and track settlement was investigated. Dynamic forces according to various rail-pad stiffness was obtained from the dynamic vehicle-track interaction analysis using DARTS-NL. Track settlement was calculated by substitution the dynamic forces into various formulas for track settlement. From the result of analysis, it was known that the track settlement is increased about 6% when the rail-pad stiffness rise about twice. And this result leads that there is only a little relationship between rail-pad stiffness and track settlement.

• BMB Reports
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• v.50 no.6
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• pp.329-334
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• 2017

Protein tyrosine phosphatases (PTPs) play crucial roles in signal transduction and their functional alteration has been detected in many diseases. PTP inhibitors have been developed as therapeutic drugs for diseases that are related to the activity of PTPs. In this study, PTP inhibitor XIX, an inhibitor of CD45 and PTEN, was investigated whether it inhibits other PTPs. Protein tyrosine phosphatase non-receptor type 2 (PTPN2) was selectively inhibited by the inhibitor in a competitive manner. Drug affinity responsive target stability (DARTS) analysis showed that the inhibitor induces conformational changes in PTPN2. Phosphorylation levels of signal transducer and activator of transcription 3 (STAT3) at Tyr-705, a crucial site for STAT3 activation and target site of PTPN2, decreased upon exposure to the inhibitor. Our results suggest that PTP inhibitor XIX might be considered as an effective regulator of PTPN2 for treating diseases related to PTPN2.

• The Research Journal of the Costume Culture
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• v.12 no.1
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• pp.12-27
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• 2004

The Tuck, an important component of modem clothing design, was analyzed through various sources of literature comprised chiefly of domestic and imported fashion magazines from 2000 to 2003. The results were as follows: 1) The Tuck was organized in horizontal, perpendicular, oblique and radial directions. Application methods included repetition, gradation, radial arrangement, sequence and alternation of individual lines. 2) The Tuck was found in a variety of forms and uses. But due to structural characteristics, its function is more psychological and aesthetic than functional. The aesthetic properties of the Tuck included rhythm, optical illusion, abstraction, and material. The structural property of the Tuck occasionally substituted bust or waist darts. 3) The individuality and originality of the Tuck was used in unpredictable ways to give spatial ornamentality and emphasis on material. This enabled aesthetically unique designs to arise. To summarize, the Tuck, a component of clothing design as a formative art, was used in a variety of methods towards developing creative clothing design.

• Journal of the Korean Home Economics Association
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• v.34 no.5
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• pp.249-264
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• 1996

The purpose of this study was to investigate automatic manipulating functions of dart of CAD system, and to classify the dart of women's front bodice. The results from this study: 1.3 CAD systems, were compared in automatic manipulating functions of dart. Gerber system & Investronica system were based on the pivot-method of dart manipulating, Yuka system was based on the slash-method. 2. It is classified and made a dart-design chart with using darts, which were as examples related to dart manipulating in text & reference of the pattern design. 3. In case of education of dart manipulation, the classified dart-design chart provides variations of a basic pattern through dart manipulation.

• Journal of the Korea Society of Computer and Information
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• v.27 no.4
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• pp.99-110
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• 2022

This study attempted to develop a bodice prototype that is the basis for the production of upper body clothing for 20s plus-size women who have distinct characteristics from women with general body types. Through this, it was intended to provide basic data necessary for the development of plus-size women's clothing, which is revitalizing the market due to the increase in the obese population. Through the first evaluation of appearance and abdominal pressure, patterns such as moving the side neck, adding the amount of armhole dart, and adding the amount of sagging were modified. Through the second evaluation, corrections such as vertical side lines, reduction of the neck of the back center line, and adding the amount of armhole darts were performed. Through the third evaluation, the final pattern drafting method was developed by vertically modifying the side line and adding the amount of back armhole darts. In the case of 20s plus-size female body types, a drafting method distinguished from the general body type was required in the method of setting the side and hem due to the protrusion of the abdomen. This study can be said to be meaningful in that it proposed a bodice prototype drafting method suitable for the body type of 20s plus-size women. In the follow-up study, it is thought that the wearability should be evaluated through actual garment wearing.

• Journal of Ginseng Research
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• v.47 no.5
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• pp.662-671
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• 2023

Background: 20(S)-protopanaxadiol (PPD), a ginsenoside metabolite, has prominent benefits for the central nervous system, especially in improving learning and memory. However, its transcriptional targets in brain tissue remain unknown. Methods: In this study, we first used mass spectrometry-based drug affinity responsive target stability (DARTS) to identify the potential proteins of ginsenosides and intersected them with the transcription factor library. Second, the transcription factor PURA was confirmed as a target of PPD by biolayer interferometry (BLI) and molecular docking. Next, the effect of PPD on the transcriptional levels of target genes of PURA in brain tissues was determined by qRT-PCR. Finally, bioinformatics analysis was used to analyze the potential biological features of these target proteins. Results: The results showed three overlapping transcription factors between the proteomics of DARTS and transcription factor library. BLI analysis further showed that PPD had a higher direct interaction with PURA than parent ginsenosides. Subsequently, BLI kinetic analysis, molecular docking, and mutations in key amino acids of PURA indicated that PPD specifically bound to PURA. The results of qRT-PCR showed that PPD could increase the transcription levels of PURA target genes in brain. Finally, bioinformatics analysis showed that these target proteins were involved in learning and memory function. Conclusion: The above-mentioned findings indicate that PURA is a transcription target of PPD in brain, and PPD upregulate the transcription levels of target genes related to cognitive dysfunction by binding PURA, which could provide a chemical and biological basis for the study of treating cognitive impairment by targeting PURA.

• Journal of the Korean Society of Costume
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• v.56 no.7 s.107
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• pp.152-166
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• 2006

The purpose of this study was to make patterns for lingerie look after examining expressive characteristics and constructive elements of lingerie look. As underwear became outerwear, position of wearing, materials, and details had changed, and the phenomenon to expose one's body has increased. The constructive elements found in the lingerie look were classified into silhouette, fastening, dart, and cutting line. Many of corset looks revealed cutting lines such as diagonal, perpendicular, and horizon. Brassiere look used perpendicular rutting lines or horizontal cutting lines passing through the bust point in order to highlight the volume by adding darts. There were styles Of chemise looks that used princess lines or separately added a brassier on the breast. Based on the examination of the elements, a total of four apparel works were created, including one flat pattern and three draping patterns. With new infra-apparel designs and patterns, this study was able to artificially highlight the body and express the beauty of costume through revelation of body. In addition, it explored the possibility that the phenomenon that underwear becomes outerwear may be a new idea of dress designing.