• Journal of the Korean Chemical Society
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• v.34 no.6
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• pp.517-526
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• 1990

The crystal structures of two alditol acetates, D-glucitol hexaacetate and xylitol pentaacetate, have been determined by diffraction methods with Mo-K$\alpha$radiation, using direct methods for phase determinations. The crystal data are: for D-glucitol hexaacetate, P2$_1$, with a = 10.275 (2), b = 8.363 (1), c = 12.560 (5) $\AA;\beta$ = 95.97 $(2)^{\circ}$, Z = 2; for xylitol pentaacetate, P2$_1$/C with a = 18.126 (1), b = 11.422 (2), c = 8.649 (1) $\AA$, $\beta = 95.03 (1)^{\circ}$, Z = 4. Both molecules have extended zigzag carbon chain conformations which differ from previous studies of the structures of D-glucitol and xylitol and also differ from NMR studies on alditol acetates. The bond lengths and angles are normal, with mean values over both structures of C($sp^3)-C(sp^3): 1.514 (10),\; C(sp^3)-O: 1.444 (6),\; C(sp^2)-O: 1.347 (9),\; C(sp^2)=O: 1.197 (6),\; C(sp^2)-C(sp^3): 1.479(9){\AA},\; C(sp^3)-C(sp^3)-C(sp^3): 114.6 (17),\; O-C(sp^3)-C(sp^3): 109.4 (23),\; C(sp^2)-O-C(sp^3): 117.4 (6),\; O=C(sp^2)-O: 122.6 (6),\; C(sp^3)-C(sp^2)-O: 111.8 (7),\; C(sp^3)-C(sp^2)=O: 125.5 (4)^{\circ}$. The atoms of acetate groups are in coplanar. There are no particularly short intermolecular contacts and the molecules are held together by van der Waals force only.

• Asian Pacific Journal of Cancer Prevention
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• v.17 no.8
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• pp.3835-3838
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• 2016

Background: Breast cancer is one of the most frequent cancer types within female populations. Silibinin is a chemotherapeutic agent ative against cancer. Niosomes are biodegradable, biocompatible, safe and effective carriers for drug delivery. Objective:To prepare nanoniosomal silibinin and evaluate its cytotoxicity inthe T-47D breast cancer cell line. Materials and Methods: Niosomes were prepared by reverse phase evaporation of a mixture of span 20, silibinin, PEG-2000 and cholesterol in chloroform and methanol solvent (1:2 v/v). The solvent phase was evaporated using a rotary evaporator and the remaining gel phase was hydrated in phosphate buffer saline. Mean size, size distribution and zeta potential of niosomes were measured with a Zetasizer instrument and then nanoparticles underwent scanning electron microscopy. The drug releasing pattern was evaluated by dialysis and the cytotoxicity of nanoniosomes in T-47D cells was assessed by MTT assay. Results: Particle size, size variation and zeta potential of the niosomal nanoparticles were measured as $178.4{\pm}5.4nm$, $0.38{\pm}0.09$ and $-15.3{\pm}1.3mV$, respectively. The amount of encapsulated drug and the level of drug loading were determined $98.6{\pm}2.7%$ and $22.3{\pm}1.8%$, respectively; released drug was estimated about $18.6{\pm}2.5%$ after 37 hours. The cytotoxic effects of nanoniosome were significantly increased when compared with the free drug. Conclusions: This study finding suggests that silibinin nanoniosomes could serve as a new drug formulation for breast cancer therapy.

• Journal of the Institute of Electronics and Information Engineers
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• v.51 no.3
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• pp.45-54
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• 2014

In this paper, We have designed and fabricated 20 InP Gunn diodes using a current limiting epitaxial structure by MINT's optimized fabrication processes. We have also packaged the fabricated InP Gunn diodes using our optimized packaging method, and then designed and fabricated a W-band waveguide FTO to measure characteristics of the packaged InP Gunn diodes. The packaged InP Gunn diode have a ceramic ring, a Au plated stud and a lid, and a Maltese cross. The fabricated InP Gunn diodes have good RF characteristics such as high output powers (11.8~17 dBm) and limiting low currents (less than 400 mA) between 92.9 and 94.78 GHz.

• The Journal of the Institute of Internet, Broadcasting and Communication
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• v.12 no.2
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• pp.43-52
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• 2012

This paper presents and analyzes laboratory test results of Interference Cancellation Digital On Channel Regenerative Repeater(IC-DOCR) to broadcast digital television signals in the Advanced Television Systems Committee(ATSC) transmission systems using single frequency networks(SFN). IC-DOCR laboratory test is classified to receiver test, transmitter test, and feedback interference cancellation test. The receiver part includes random noise, single echo, multi-path ensembles, and adjacent channel interference test. The transmitter part includes out-of channel emission, equality of transmitting signal, and phase noise test. By the laboratory test, the receiver part of the IC-DOCR eliminates 28dB of feedback signal higher than the received signal and has 17.8dB at TOV(Threshold Of Visibility) under random noise environment. Also, the transmitter part satisfies the specification of US FCC(Federal Communications Commission) as well as maintains good output signal quality for guaranteeing more than SNR 30dB.

• The Journal of Korean Institute of Electromagnetic Engineering and Science
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• v.20 no.8
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• pp.680-687
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• 2009

In this paper, we propose a substrate integrated waveguide(SIW) power divider to yield excellent broadband isolation performance. In order to achieve high broadband isolation, a two stage Wilkinson power divider is employed in SIW. The measurement results show the insertion loss($S_{21}$, $S_{31}$ to be $4.0{\pm}0.5$ dB) and input return loss($S_{11}$ of 10 dB) from 13.12 GHz to 16.14 GHz. Moreover, the results show that the output return loss and isolation between output ports are larger than 10 dB between 10.37 GHz and 17.64 GHz.

• The Journal of Korean Institute of Electromagnetic Engineering and Science
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• v.13 no.9
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• pp.907-915
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• 2002

In this paper, a compact digital phase shifter to be used an active phased array antenna system for satellite communications was proposed. The even and odd mode analysis for a given reflection-type phase shifter, which uses a folded hybrid coupler as a base element, was performed and the design parameters were derived. Also, to verify experimentally the electrical performances of the proposed structure, X-band 4-bit digital phase shifter was designed and fabricated using Teflon soft substrate $({\varepsilon}_r; =\;2.17)$. Its circuit size was less than 3.5 cm $\times$ 3.0 cm, and it exhibited at least 50 % size reduction as compared with the conventional unfolded configuration. The experimental results of the fabricated phase shifter showed that the average insertion loss and insertion loss variation were less than 3.5 dB, $\pm$ 0.6 dB within the operating band, 7.9 ~ 8.4 GHz, respectively. And, input and output return loss were more than 10 dB, respectively. Also, the phase response of the phase shifter showed 4-bit operation with $\pm$3$^{\circ}$ rms phase error.

• The Journal of Korean Institute of Electromagnetic Engineering and Science
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• v.22 no.1
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• pp.76-80
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• 2011

This paper has proposed a 3~5 GHz low-power and wideband LNA(Low Noise Amplifier), which has been implemented in a 0.18-${\mu}m$ CMOS technology. The proposed LNA has basically the noise-cancelling topology to achieve a balun-function, wideband input matching, and relative low noise figure. In addition, it has utilized a 2nd-order LC-band-pass filter(BPF) as its output load to achieve higher power gain and lower noise figure with the lowest dc power consumption among previously reported works. The proposed amplifier consumes only 3.94 mA from a 1.8 V supply voltage. The simulation results show a power gain of more than +17 dB, a noise figure of less than +4 dB, and an input IP3 of -15.5 dBm.

• Food Science and Biotechnology
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• v.15 no.2
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• pp.202-206
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• 2006

The oxidation stability of fish oil containing omega-3 polyunsaturated fatty acids (PUFAs), which is very susceptible to oxidative deterioration, needs to be improved before it can be successfully applied to functional foods. The antioxidant activities of 17 species of materials in anchovy oil (AO) were compared and a potent antioxidant was determined to improve the shelf-life of refined AO. Antioxidant activities of the 0.05% (w/w) materials in AO were compared against control during storage at $30^{\circ}C$ for 10 days. While no antioxidant effect was shown in alpha tocopherol against control, 3 species of grapefruit seed extracts (GSEs), astaxanthin (AX), soybean lecithin, and green tea extract showed good antioxidant activities. Especially, GSE B, GSE C, and AX showed significantly high peroxide inhibitory activities (PIAs) of $16.2{\pm}2.1$, $20.{\pm}3.5$, and $17.7{\pm}3.5%$, respectively, after the 4th day (p<0.01). Radical scavenging activities (RSAs) of GSE B, GSE C, and AX were $85.1{\pm}0.8$, $95.3{\pm}0.3$, and $85.9{\pm}0.8%$, respectively. Correlation between PIAs and RSAs was high ($R^2=0.926$) in GSE B, GSE C, and AX. Therefore, we concluded that one of the main antioxidative mechanisms of GSEs and AX must operate through an RSA pathway. The $RC_{50}$ (concentration required for 50% reduction of 1,1-diphenyl-2-picryl-hydrazyl, DPPH) of GSE C was $258\;{\mu}g/mL$.

• The Journal of Korean Institute of Electromagnetic Engineering and Science
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• v.10 no.6
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• pp.805-814
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• 1999

In this paper, elliptic function bandpass filters using ceramic coaxial resonators are designed. Since elliptic function filters have better performance of frequency selectivity than those based on Butterworth or Chebyshev, therefore it is possible to make better use of limited frequency resources. Elliptic function bandpass filters using ceramic coaxial resonators are designed for reducing it's size, weight, cost and for easy manufacturing and tuning. From measurements, an accurate resonator model is obtained and the coupling coefficient values are extracted. Based on these results, elliptic function bandpass filters are designed. The experimental results have shown that the 8th order elliptic function filter of 959 MHz center frequency with 28 MHz bandwidth using coaxial ceramic resonators have about more tan 17 dB return loss, 5 dB insertion loss, more than 20 dB attenuation at $f_c\pm$5 MHz.

• The Journal of Korean Institute of Electromagnetic Engineering and Science
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• v.23 no.9
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• pp.1058-1064
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• 2012

In this paper, an absorber based on metamaterial is proposed to improve the isolation of conventional WCDMA indoor repeater antenna. The proposed absorber is composed of Double Split Ring Resonators(DSRRs) and Complementary Spiral(CS) structure. The proposed absorber based on metamaterial is $9.6mm{\times}9.6mm{\times}1.2mm$ and absorption is about 94 % at 2.2875 GHz. The proposed antenna, which proposed absorber is applied to conventional WCDMA indoor repeater antenna, has isolation over 85 dB. Isolation is improved more than 10 dB compared with the conventional antenna. The VSWR is lower than 2 at WCDMA band from 1.92 GHz to 2.17 GHz. The radiation patterns are $60^{\circ}{\pm}10^{\circ}$ E-plane and H-plane, respectively. And, the gain is more than 6 dBi. The volume of proposed antenna with absorber based on metamaterial is $90mm{\times}90mm{\times}44.8mm$.