• Proceedings of the Korea Society for Energy Engineering kosee Conference
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• 2001.11a
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• pp.43-50
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• 2001

• 월간산업보건
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• s.268
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• pp.43-45
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• 2010

• BMB Reports
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• v.43 no.4
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• pp.263-267
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• 2010

To characterize the biochemical properties of the PP2A regulatory B subunit, PPP2R5D, we analyzed its phosphorylation sites, stoichiometry and effect on holoenzyme activity. PPP2R5D was phosphorylated on Ser-53, Ser-68, Ser-81, and Ser-566 by protein kinase A, and mutations at all four of these sites abolished any significant phosphorylation in vitro. In HEK293 cells, however, the Ser-566 was the major phosphorylation site after PKA activation by forskolin, with marginal phosphorylation on Ser-81. Inhibitory tyrosine phosphorylation on Tyr-307 of the PP2A catalytic C subunit was decreased after forskolin treatment. Kinetic analysis showed that overall PP2A activity was increased with phosphorylation by PPP2R5D phosphorylation. The apparent Km was reduced from $11.25\;{\mu}M$ to $1.175\;{\mu}M$ with PPP2R5D phosphorylation, resulting in an increase in catalytic activity. These data suggest that PKA-mediated activation of PP2A is enabled by PPP2R5D phosphorylation, which modulates the affinity of the PP2A holoenzyme to its physiological substrates.

• The Bulletin of The Korean Astronomical Society
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• v.35 no.2
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• pp.43.1-43.1
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• 2010

A novel method to characterize the topology of the early-universe intergalactic medium during the epoch of cosmic reionization is presented. The 21-cm radiation background from high redshift is analyzed through calculation of the 2-dimensional (2D) genus. The radiative transfer of hydrogen-ionizing photons and ionization-rate equations are calculated in a suite of numerical simulations under various input parameters. The 2D genus is calculated from the mock 21-cm images of high-redshift universe. We construct the 2D genus curve by varying the threshold differential brightness temperature, and compare this to the 2D genus curve of the underlying density field. We find that (1) the 2D genus curve reflects the evolutionary track of cosmic reionization and (2) the 2D genus curve can discriminate between certain reionization scenarios and thus indirectly probe the properties of radiation-sources. Choosing the right beam shape of a radio antenna is found crucial for this analysis. Square Kilometer Array (SKA) is found to be a suitable apparatus for this analysis in terms of sensitivity, even though some deterioration of the data for this purpose is unavoidable under the planned size of the antenna core.

• Journal of Technologic Dentistry
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• v.43 no.1
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• pp.13-18
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• 2021

Purpose: This study aimed to compare the flexural properties and perform the Weibull analysis of photo-curing three-dimensional (3D) printing resin. Methods: Photo-curing temporary resin (3D polymer) was used as a printing resin. Specimens (65 × 10 × 3.3 ㎣) were prepared following the ISO 20975-1 guidelines and according to the different printing orientations using a digital light processing 3D printer (D2 120; Dentium). The flexural strength (FS), flexural modulus, and work of fracture (WOF) were measured using a universal testing machine (Instron 3344; Instron) at a crosshead speed of 5 mm/min. Results: In this study, the 0° orientation exhibited higher FS and WOF than the 45° orientation. Significant differences were found among the printing orientations (p<0.05). Specimens printed at the 0° orientation were the most accurate. In the Weibull analysis, 0° showed the greatest Weibull modulus (m), which represents a higher reliability. Conclusion: 3D printing should be selected and used by considering flexural properties, size accuracy, and reliability.

• Journal of Korean Society for Quality Management
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• v.43 no.1
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• pp.85-102
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• 2015

Purpose: This study is aimed to develope effective guidelines of R&D institute with regard to general management cost, by analyzing the management characteristics of 14 domestic R&D institutes general management costs. Methods: The bootstrapping method is applied to obtain the average general management cost of 14 R&D institute and the effective R&D institutes are presented by comparing the general management costs of R&D and the rate of inflation. Results: The results show that the average R&D general management cost of 14 R&D institutes is 3.32% and, in general, it turns out that the R&D general management costs do not reflect the inflation rate after a comparative analysis of the variation of the R&D general management costs. In addition, the results of cost-effective analysis show that only 5 R&D institutes are efficient in R&D activities. Conclusion: Applying a uniform standard of R&D general management costs although their management characteristics are different, can cause the impediment to the independence and transparency of R&D institutes. Therefore it is recommended a strict implementation with respect to the monitoring system of each R&D institute and the budget policy methods which are reflected management characteristics.

• Journal of the Institute of Electronics Engineers of Korea TC
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• v.43 no.5 s.347
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• pp.147-155
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• 2006

In this paper, we propose a new Mushroom-like PBG concepts for designing with forbidden frequency band-gap at low frequency. These design rules are based on enhancing the capacitance per unit area using modified top-patch of mushroom PBG with no increase on the overall thickness of the substrate board. Also, in this paper, a new approach to suppress the surface wave from antenna is proposed by embedding compact mushroom PBG in the substrate. Comparisons between the results from a conventional patch antenna to a patch antenna on a PBG substrate show that the reduction in the surface wave level is remarkable. This can be observed in the radiation pattern and the maximum gain. The maximum gain for reference patch antenna is $6.43dB{\imath}$ at 5.37 GHz, while the maximum gain for the patch antenna with normal mushroom and vane mushroom PBG is $7.24dB{\imath}\;and\;7.53dB{\imath}$at 5.14 GHz. The back radiation is also considerably reduced; this will lead, of course, to an increase in the antenna efficiency.

• 수도
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• v.24 no.6 s.87
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• pp.32-43
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• 1997

• Journal of Korean Institute of Industrial Engineers
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• v.43 no.2
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• pp.100-111
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• 2017

Evaluating the performance of R&D Activity is complicated because it is hard to quantify the R&D results unlike the traditional manufacturing or service industries. Recently, to overcome this, process-focused evaluation methods applying the philosophy of quality into R&D environment have been introduced. However, these quality activities are mainly conducted without feedback system after the evaluation work is done. The aim of this study is to present a R&D quality diagnosis framework to obtain the improvement opportunities from R&D process perspective. The research is designed as follows : First, R&D standard process and R&D quality elements are derived from a literature review. Second, the diagnosis objects are obtained by investigating the R&D quality elements at each R&D steps. Third, a two-dimensional diagnosis model, which enables the objective measurement of the 'system compatibility' and 'accomplish level', is presented. The proposed method can provide an effective way to find opportunities for efficient quality improvement of R&D process.

• Proceedings of the Materials Research Society of Korea Conference
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• 2008.11a
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• pp.43.1-43.1
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• 2008