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Report on the side-effects of Pharmacopuncture Lubricants(CF, JsD) (경락약침의 윤제(CF, JsD)에 의한 부작용 사례보고)

  • Lee, Jong-Young;Kang, Hyun-Min;Lim, Chung-San;Kwon, Ki-Rok
    • Journal of Pharmacopuncture
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    • v.10 no.3
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    • pp.137-142
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    • 2007
  • Objectives This study aims to report inflammatory reactions of Pharmacopuncture lubricants (CF and JsD) when administered on GB21, GB20, and TE23 in clinical trials. Methods Follow-up studies were made on each patient's clinical observation and specific managemen. Results 1. Inflammation induced by pharmacopuncture lubricants were limited to local area of administration. 2. Intensity of inflammation was depended on the patient's condition. 3. Inflammation caused pain, skin flare, and discomfort on the patient. Inflammation subsided when dissipating technique was rendered with the conventional acupuncture needle. Conclusions It appears that prolonged usage of pharmacopuncture lubricant on the specific point can induce inflammation, thus using alternative pharmacopuncture is recommended.

Activity of virE promoter in Agrobacterium tumefaciens A348 (Agrobacterium tumefaciens A348에서 virE 프로모터의 활성)

  • 음진성
    • Journal of Plant Biology
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    • v.34 no.4
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    • pp.331-339
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    • 1991
  • To elucidate the regulatory mechanism of virE operon from vir regions (virA, virB, virC, virD, virG, virE) of pTiA6 which have been known to be essential for efficient crown gall tumorigenesis in plants, the activity of the truncated virE, promoter was analyzed. pSM358cd, a recombinant plasmid in which virE :: Tn3-HoHo1 (Tn3-promoterless lacZ) was cloned into SalI site of pVK102, was digested with SalI, and virE :: Tn3-HoHo1 was seperated from pVK102. To construct the truncted virE recombinant plasmids (pJS031, pJS051, pJS102, pJS201, pJS301), 5'-end of vireE promoter was deleted with BAL31 and cloned into pVK102 and then transferred into a. tumefaciens A348(pTiA6). According to the activity of the truncated virE promoter in recombinant plasmids, they were classified into two groups, pJS031, pJS051, pJS101 and pJS201 belong to a functional group and pJS301 is a non-functional. The size of deleted nucleotides of pJS201 and pJS301 seemed to be about 130 nucleotides and about 250 nucleotides from 5'-end of virE promoter, respectively. Hence it was thought that the essential site of the virE promoter was located between about 130th nucleotide and 250th nucleotide from 5'-end of the virE promoter.

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Unified Motion and Force Control of JS-10 Robot Manipulator Based on Operational Space and 3D CAD (작업공간과 3D CAD를 기반으로 하는 JS-10 매니플레이터의 운동과 힘의 통합제어)

  • Ahn, D.S.;Nguyen, Van Phuc
    • Journal of Power System Engineering
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    • v.16 no.3
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    • pp.57-63
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    • 2012
  • 본 논문은 작업공간상에서 로봇 운동과 힘의 통합제어를 구현할 수 있는 플랫폼의 구현에 초점을 두고 있다. 조립 또는 디버링 같은 접촉작업에서의 매니플레이터 효율성 제고나 친 인간 환경에서의 휴머노이드 로봇의 안정성을 위해서는 종래의 PID 제어나 관절공간상에서의 CTM(Computed Torque Method) 제어보다는 작업공간상에서의 운동과 힘의 통합제어를 실시해야 한다. 이것을 위해서는 작업공간상에서의 엔드이펙트(end-effector, E-E)에 대한 동역학식과 자코비안(jacobian)을 도출해야 하며 이를 위해서는 각종 동적파라미터의 정확한 동정이 중요하다. 본 논문에서는 3D CAD 모델링, MATLAB, 동역학 시뮬레이터를 활용하여 로봇 모델링, 동역학식과 동적 파라미터 추출, 운동과 힘의 실시간 통합제어 시뮬레이션등을 쉽고 일관되게 진행할 수 있는 플랫폼을 구현하였고 적용예로써 JS-10로봇을 택해서 그 효용성을 입증하였다.

The Study on Acute°§Subacute Toxicity of Juglandis Semen Herbal-acupuncture(JsD) (호도약침(胡桃藥鍼)의 급성(急性) 아급성(亞急性) 독성(毒性)에 관(關)한 실험적(實驗的) 연구(硏究))

  • Kang, Kye-Sung;Kwon, Gi-Rok
    • Journal of Pharmacopuncture
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    • v.4 no.3
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    • pp.85-92
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    • 2001
  • Objective : This study was purposed to investigate the acute. subacute toxicity of Herbal acupuncture with Juglandis Semen(JsD) in mice and rats. Methods & Results: Balb/c mice were injected intraperitoneally with JsD for $LD_{50}$ and acute toxicity test Sprague-Dawley rats were injected intraperitoneally with JsD for subacute toxicity test. Results: The results obtained were summarized as follows; 1. LD50 was uncountable as could not find the expired of treat group. 2. The clinical signs and body weight changes of mice treated with 0.2cc, 0.4cc JsD were not affected during the acute toxicity test. 3. In acute toxicity test of serum biochemical values of mice, total protein was increased in treat-l group, compared with normal group, and total cholesterol was increased in treat-2 group, compared with normal group.(P<0.05) 4. In subacute toxicity test, main toxic syndrome was not found. 5. The body weight was decreased in treat-2 group, compared with normal group and relative liver weight was decreased in treat-1, 2 group, compared with normal group in subacute toxicity test.(P<0.05) 6. In subacute toxicity test, WBC, MCH, MCHC were decreased in treat-2 group and RBC was increased in treat-2 group, compared with normal group in complete blood count test.(P<0.05) 7. In subacute toxicity test, treat groups were not changed serum biochemical values of rats, compared with normal group.(P<0.05) Conclusions: According to the results, Herbal-acupuncture with Juglandis Semen caused no toxicity.

Chemical Investigation on an Endophytic fungus Gibberella moniliformis JS1055 Derived from a Halophyte Vitex rotundifolia

  • Kim, Jung Wha;Ryu, Jiyoung;Shim, Sang Hee
    • Natural Product Sciences
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    • v.24 no.3
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    • pp.189-193
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    • 2018
  • Chemical investigation of the ethyl acetate extract of Gibberella moniliformis JS1055 endophytic fungus derived from a halophyte, Vitex rotundifolia, led to the isolation of nine compounds including 7-butyl-6,8-dihydroxy-3(R)-pent-11-enylisochroman-1-one (1), 7-butyl-6,8-dihydroxy-3(R)-pentylisochroman-1-one (2), 7-butyl6,8-dihydroxy-3(R)-pentylisochroman-1-one (3), $5{\alpha},8{\alpha}$-epidioxyergosta-6,9(11),22-trien-3-ol (4), ergosterol peroxide (5), tetradecanoic acid (6), 8-O-methylfusarubin (7), nicotinic acid (8) and adenosine (9). They were identified by extensive spectroscopic data analysis including 1D, 2D ($^1H-^1H$ COSY, HSQC, HMBC) NMR, and ESIMS. All the isolates (1-9) are reported for the first time from this endophytic fungus.

Development of 3D World History Map Webpage Using Three.js (Three JS를 이용한 삼차원 세계역사지도 웹페이지 구현)

  • Hyo Hyun Choi;Kim Sang Gyu
    • Proceedings of the Korean Society of Computer Information Conference
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    • 2023.01a
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    • pp.281-282
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    • 2023
  • 본 논문에서는 전세계의 역사들을 시간대별로 정리하여 이용자들에게 제공하는 3차원 세계역사지도 웹페이지를 구현한다. 이를 통해, 사용자가 3차원 공간 안에서 지구본을 돌려보며 본인이 알고 있던 역사와 동시대에 일어났던 사건들을 비교해보거나, 몰랐던 사실들을 깨달음으로써 전 세계 역사를 연결 지어 인식하게 하고, 나아가 역사 학습 흥미를 일으키고자 한다. Three JS를 이용하여 웹페이지 내에 삼차원 공간을 렌더링하였고, Raycasting 기법 등의 방법으로 흥미를 유발할 수 있는 상호작용 기능을 구현하였다. 또한 실시간 데이터베이스는 구글의 Firebase 서비스를 이용하여 구현하였다.

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Development of Drone Airspace Information Providing Scheme using Mapbox (Mapbox를 이용한 드론 관련 구역 정보 제공 방법 구현)

  • Choi, Hyo Hyun;Kim, Hyung Gyu
    • Proceedings of the Korean Society of Computer Information Conference
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    • 2020.07a
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    • pp.321-322
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    • 2020
  • 본 논문에서는 대한민국에서 드론을 포함한 UAV를 합법적으로 비행할 수 있도록 관련 구역 정보를 제공하는 서비스를 구현한다. Mapbox API를 이용하여 3D지도를 설정하고 드론 관련 구역 정보를 레이어화 한다. 레이어는 GL JS를 이용하여 인터페이스를 구성해 지도상에 나타낸다. GL JS로 검색, 네비게이션 기능의 인터페이스를 구성한다. 작성한 결과물을 서버에 업로드하여 서비스를 구현하였다.

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Habitats Environmental and Population Characteristics of Iris koreana Nakai, a Rare and Endemic Species in Korea (한반도 희귀·특산식물 노랑붓꽃의 자생지 환경 및 개체군 특성)

  • Pi, Jung-Hun;Park, Jeong-Geun;Jung, Ji-Young;Park, Jeong-Seok;Suh, Gang-Uk;Son, Sung-Won
    • Korean Journal of Ecology and Environment
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    • v.49 no.2
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    • pp.102-109
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    • 2016
  • The sustainability of Iris koreana, a rare and endemic plant designated by the Korea Forest Service, is threatened due to artificial factors such as habitats loss and climate change etc. and internal factors such as changes in biological properties of the habitats etc. but conservation biology research has not been performed in South Korea. The objective of this study is to establish the species conservation strategies by analyzing the characteristics of their habitats, including: 1) Population characteristics, and 2) habitat analysis of the vegetation and abiotic environments. From April to May, 2015, population characteristics [density (stems $m^{-2}$), flowering rate (%) and leaf area size ($cm^2$)] in I. koreana habitats such as Buan1~6 (BA1~6), Jangseong1~2 (JS1~2) and vegetation characteristics (phytosociological research and ordination analysis), and abiotic environments [soil temperature ($^{\circ}C$), soil humidity (%), transmitted light ($mol{\cdot}m^{-2}{\cdot}d^{-1}$) and canopy openness (%)] were measured. I. koreana was mainly distributed at elevation 50 to 150 m and 2 to $11^{\circ}$ slope. Slope direction was shown as 90 to $193^{\circ}$. The average degree of canopy openness was 11.9%. It showed the highest at BA2 (17.5) and the lowest at JS1 (7.7). The average degree of transmitted light was $6.3mol{\cdot}m^{-2}{\cdot}d^{-1}$. It showed the highest at BA2 (10.1) and the lowest at JS1 (3.6). Population density showed average 25.8 (stems $m^{-2}$). It showed the highest at JS2 (19.7) and the lowest at JS1 (9.3). flowering stems showed average 16.9 (stems). It showed the highest at BA3 (35) and the lowest at BA5 (4). Leaf area size was average $94.1cm^2$.

A Study on the Educational Applications of the Virtual Reality Space Design Simulation (가상현실 공간설계 시뮬레이션의 교육적 활용 탐색)

  • Kim, Ji-Yun;Jung, Bokmoon;Yoo, Jiyeon;Lee, Tae Wuk;Kim, Kwihoon
    • Proceedings of the Korean Society of Computer Information Conference
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    • 2021.07a
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    • pp.439-442
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    • 2021
  • 가상현실은 제4차 산업혁명 시대 신산업으로 꼽히는 기술 중 하나이다. 본 연구에서는 가상현실 공간설계의 교육적 가능성을 확인하고 교육적 활용을 위한 툴로서 3D 컴퓨터 그래픽 제작 소프트웨어인 블렌더와 3D 객체를 웹에서 쉽게 렌더링해주는 자바스크립트 라이브러리 three.js를 이용한 건축 내외장재 시뮬레이션 프로그램의 프로토타입을 개발 및 제안하였다. 본 연구에서 제안한 방식으로 학습자들은 자유도 높은 가상공간 공간설계가 가능하여 조형놀이의 형태로 학습을 즐길 수 있을 것으로 기대된다. 후속 연구로는 본 연구에서 구현한 프로토타입과 같은 방식으로 가상현실 공간설계 시뮬레이션을 할 수 있는 교육 프로그램 개발 및 효과성 검토를 실시할 것을 제안하였다.

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Mediating Effect of Positive Psychological Capital on the Relationship between Emotional Labor and Job Satisfaction in Clinical Nurses (임상간호사의 감정노동과 직무만족 관계에서 긍정심리자본의 매개효과)

  • Yeo, Su Jin
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.21 no.4
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    • pp.400-409
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    • 2020
  • This descriptive research study investigated the mediating effect of positive psychological capital (PPC) on the relationship between emotional labor (EL) and job satisfaction (JS) of clinical nurses. The data was collected from 274 nurses working for two hospitals in the D city, Korea, from 7 Sep. 2016 through 23 Sep. 2016. General characteristics, EL, JS, and PPC were surveyed using structured questionnaires. Statistical analysis was performed using descriptive statistics, ANOVA, and stepwise multiple regression analysis with SPSS/WIN 21.0. The mediating effect of PPC on the relationship between EL and JS was tested using Baron & Kenny's 3-step hierarchical regression analysis. There were negative correlations between EL and JS (r=-.36, p<.001) and EL and PPC (r=-.25, p<.001) and a positive correlation between JS and PPC (r=.47, p<.001). In addition, the PPC, had a partial mediating effect (z=-3.44, p=.001) on the relationship between EL and JS. It is proposed, based on the results, to develop an organized intervention program that enhances job satisfaction by reducing emotional labor and strengthening positive psychological capital in clinical nurses.