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멍게(Halocynthia roretzi) 비타민 D 수용체 상동체 동정 및 전사활성 (Characterization and Transcriptional Activity of a Vitamin D Receptor Ortholog in the Ascidian Halocynthia roretzi)

  • 이정환;손영창
    • 한국수산과학회지
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    • 제48권6호
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    • pp.913-919
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    • 2015
  • In vertebrates, the vitamin D receptor (VDR), a member of the nuclear receptor superfamily, binds the biologically active ligand $1{\alpha},25-(OH)_2$-vitamin $D_3$ (1,25 $D_3$). Nearly all vertebrates, including Agnatha, possess a VDR with high ligand selectivity for 1,25 $D_3$ and related metabolites. Although a putative ancestral VDR gene is present in the genome of the chordate invertebrate Ciona intestinalis, the functional characteristics of marine invertebrate VDR are still obscure. To elucidate the ascidian Halocynthia roretzi VDR (HrVDR), we cloned full-length HrVDR cDNA and investigated the transcriptional activity of HrVDR in HEK293 cells. HrVDR consists of 1,680 nucleotides (559 amino acids [aa]), including a short N-terminal region (A/B domain; 26 aa), DNA-binding domain (C domain; 72 aa), hinge region (D domain; 272 aa), and C-terminal ligand-binding domain (E domain; 161 aa). The amino acid sequence identity of HrVDR was greatest to that of C. intestinalis VDR (56%). In the luciferase reporter assays, the transcriptional activity of HrVDR was not significantly increased by 1,25 $D_3$, whereas the farnesoid X receptor agonist GW4064 increased the transactivation of HrVDR. These results suggest the presence of a novel ligand for and a distinct ligand-binding domain in ascidian VDR.

강우레이더의 3차원 가시화를 위한 데이터 변환 및 표출기법 (Data Transformation and Display Technique for 3D Visualization of Rainfall Radar)

  • 김형훈;박현철;최영철;김태수;정윤재
    • 한국멀티미디어학회논문지
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    • 제20권2호
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    • pp.352-362
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    • 2017
  • This paper proposes an algorithm for automatically converting and displaying rainfall radar data on a 3D GIS platform. The weather information displayed like rainfall radar data is updated frequently and large-scale. Thus, in order to efficiently display the data, an algorithm to convert and output the data automatically, rather than manually, is required. In addition, since rainfall data is extracted from the space, the use of the display image fused with the 3D GIS data representing the space enhances the visibility of the user. To meet these requirements, this study developed the Auto Data Converter application that analyzes the raw data of the rainfall radar and convert them into a universal format. In addition, Unity 3D, which has good development accessibility, was used for dynamic 3D implementation of the converted rainfall radar data. The software applications developed in this study could automatically convert a large volume of rainfall data into a universal format in a short time and perform 3D modeling effectively according to the data conversion on the 3D platform. Furthermore, the rainfall radar data could be merged with other GIS data for effective visualization.

3D Object를 활용한 건설폐기물의 자동화산정 시스템 개발 (A Development of Automatic Quantification System of C&D Waste By Using 3D Objects.)

  • 김창학;이경희;김효진
    • 한국건설관리학회:학술대회논문집
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    • 한국건설관리학회 2008년도 정기학술발표대회 논문집
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    • pp.388-391
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    • 2008
  • 향후 국내의 주택건설 산업은 신규 택지개발에 의한 주택공급 방식보다는 기존 주택의 재개발 및 재건축에 더 큰 비중을 둘 수밖에 없으며, 현재 그러한 추세가 급속하게 확산되고 있다. 또한 재고주택 중 공동주택이 50% 이상을 차지하고 있으며, 이들의 유지보수, 리모델링 및 재건축은 주거지의 슬럼화 방지, 건물성능 저하에 따른 재난방지 등을 위하여 반드시 필요한 분야가 되었다. 이에 따라 건설폐기물의 재활용에 대한 관심 또한 매우 커져가고 있다. 따라서 정부나 민간에서는 건설폐기물의 발생량을 줄이기 위해 많은 노력을 하고 있다. 그러나 건설폐기물의 발생량을 정확히 예측하고 관리하기 위한 시스템의 개발에 대한 노력은 거의 없는 실정이다. 폐기물의 발생량을 예측하기 위한 기준의 미비로 인해 많은 사회적 비용이 발생하고 있다. 따라서 본 연구에서는 CAD 도면과 3D object를 활용하여 건설폐기물의 발생량을 쉽게 예측할 수 있는 방안을 제시한다.

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CYCLES THROUGH A GIVEN SET OF VERTICES IN REGULAR MULTIPARTITE TOURNAMENTS

  • Volkmann, Lutz;Winzen, Stefan
    • 대한수학회지
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    • 제44권3호
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    • pp.683-695
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    • 2007
  • A tournament is an orientation of a complete graph, and in general a multipartite or c-partite tournament is an orientation of a complete c-partite graph. In a recent article, the authors proved that a regular c-partite tournament with $r{\geq}2$ vertices in each partite set contains a cycle with exactly r-1 vertices from each partite set, with exception of the case that c=4 and r=2. Here we will examine the existence of cycles with r-2 vertices from each partite set in regular multipartite tournaments where the r-2 vertices are chosen arbitrarily. Let D be a regular c-partite tournament and let $X{\subseteq}V(D)$ be an arbitrary set with exactly 2 vertices of each partite set. For all $c{\geq}4$ we will determine the minimal value g(c) such that D-X is Hamiltonian for every regular multipartite tournament with $r{\geq}g(c)$.

Determination of the Structure for Polysubstituted Flavonoid and 6-C-Glucosyl Flavonoids using $^{13}C-^{1}H$ Long Range Couplings

  • Lee, Min-Won
    • Archives of Pharmacal Research
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    • 제17권6호
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    • pp.487-489
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    • 1994
  • A flavone glycoside was isolated from the leaves of Betula platyphylla var. latifolia and characterized as $4, 6-Dimethoxy-5-hydroxyflavone-7-O-{\beta}-D-glucoside(pectolinarigenin-7-O-{\beta}-D-glucopy-ranoside)$ by method of chemical and NMR spectral analysis. $^13C-^1H$ long range coupling was confirmative for determination of its substituted position. In connection with this study, 6-C-Glucosylnalingenin and 6-C-Glucosylaromadendrin were confirmed its structures using this technique.

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건축물의 안전성 향상을 위한 Spacer의 제조 (Preparation of Spacer for Safety Improvement of Architecture)

  • 홍성수;강기준;한지원
    • 한국안전학회지
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    • 제13권3호
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    • pp.45-50
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    • 1998
  • The low grade domestic kaoline, such as pink-C and white-D, was converted to metakaoline, which has pozzolanic reactivity by heat treatment in the temperature range of $600^{\circ}C$ to 100$0^{\circ}C$ for preparing the spacer. The spacer was used for supporting the reinforced steel rod during construction to improve the safety of architecture. Pink-C and white-D were completely dehydroxylated when burnt at 80$0^{\circ}C$ for 1 hour and converted to metakaoline. The compressive strengths of specimens added calcined pink-C were lower than those of press molding mortar products inspite of calcining conditions. When white-D with calcined 80$0^{\circ}C$ and 100$0^{\circ}C$ for 1 hour was mixed 30% in the weight ratio of cement, the specimens cured 28 days had 338 $kg/cm^2$ and 347 $kg/cm^2$ of compressive strengths, respectively.

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인공영양아의 에너지, 칼슘 및 철분 섭취에 관한 연구 (The Study of Nutrient Intakes of Formula-Fed Infants from Formula and Solids in Early Infancy)

  • 배현숙
    • Journal of Nutrition and Health
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    • 제29권5호
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    • pp.517-527
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    • 1996
  • The food consumption of 148 healthy infants from 4 to 6 months of age have been measured. Three groups were assigned to change of feeding pattern. Formula group(FF, n=102) were fed formula from birth till 6 months of age. Convert 1 group (C1F, n=14) and Convert 2 group (C2F, n=32) were fed breast milk and mixed milk at 2months of age afterthat switched to formula milk, respectively. All infants received solids (solid foods) from 4 months of age. No significant difference was found in the intake of nutrients among three feeding groups excluding carbohydrate intake of C1F-female at 4 months of age. No significant difference was found in the intake of nutrients among three feeding groups excluding carbohydrate intake of C1F-female at 4 months of age. The FF-female(70.9g/d) and C2F-female(66.9g/d) had significantly higher carbohydrate intake when compared to the C1F-female (54.3g/d). The average total energy intake at 4, 6 months were 648.3 and 709.7kcal/d among all infants. At 4 and 6 months of age, mean intake of nutrients was as follows. Calcium intake was 526.7mg/d and 760.0mg/d at 4 and 6 months of age respectively. Iron intake was 8.3mg/d and 10/5mg/d at 4 and 6 months of age respectively. Calories from solids provided 22.5% of total energy intake at 4 months of age, and nearly 32% at 6 months of age. The average energy and protein intakes of all infants were less than the RDA for calcium and iron at 4, 6 months of age.

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Modified Materka Model를 이용한 4H-SiC MESFET 대신호 모델링 (4H-SiC MESFET Large Signal Modeling using Modified Materka Model)

  • 이수웅;송남진;범진욱
    • 한국전자파학회논문지
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    • 제12권6호
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    • pp.890-898
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    • 2001
  • Modified Materka-Kacprzak 대신호 MESFET(Metal Semiconductor Field Effect Transistor) model을 사용하여 4H-SiC MESFET의 대신호 모델링을 수행하였다. Silvaco사의 소자 시뮬레이터인 ATLAS를 사용하여 4H-SiC MESFET 소자 시뮬레이션을 수행하고, 이 결과를 modified Materka 대신호 모델을 사용하여 모델링 하였다. 시뮬레이션 및 모델링 결과는 -8 V의 pinch off 전압과 $V_{GS}$ =0 V, $V_{DS}$ =25 V에서 $I_{DSS}$270 mA/mm, $G_{m}$ =52.8 ms/mm를 얻을 수 있었고, 전력 특성 시뮬레이션을 통해 2GHz, $V_{GS}$ =-4V, $V_{DS}$ =25 V에서 10dB의 Gain과 34dBm(1 dB compression point)의 출력전력, 7.6W/mm의 전력밀도, 37%의 PAE(power added efficiency)를 얻을 수 있었다.다.

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Collision-induced Energy Transfer and Bond Dissociation in Toluene by H2/D2

  • Ree, Jongbaik;Kim, Yoo Hang;Shin, Hyung Kyu
    • Bulletin of the Korean Chemical Society
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    • 제34권12호
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    • pp.3641-3648
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    • 2013
  • Energy transfer and bond dissociation of $C-H_{methyl}$ and $C-H_{ring}$ in excited toluene in the collision with $H_2$ and $D_2$ have been studied by use of classical trajectory procedures at 300 K. Energy lost by the vibrationally excited toluene to the ground-state $H_2/D_2$ is not large, but the amount increases with increasing vibrational excitation from 5000 and $40,000cm^{-1}$. The principal energy transfer pathway is vibration to translation (V-T) in both systems. The vibration to vibration (V-V) step is important in toluene + $D_2$, but plays a minor role in toluene + $H_2$. When the incident molecule is also vibrationally excited, toluene loses energy to $D_2$, whereas it gains energy from $H_2$ instead. The overall extent of energy loss is greater in toluene + $D_2$ than that in toluene + $H_2$. The different efficiency of the energy transfer pathways in two collisions is mainly due to the near-resonant condition between $D_2$ and C-H vibrations. Collision-induced dissociation of $C-H_{methyl}$ and $C-H_{ring}$ bonds occurs when highly excited toluene ($55,000-70,400cm^{-1}$) interacts with the ground-state $H_2/D_2$. Dissociation probabilities are low ($10^{-5}{\sim}10^{-2}$) but increase exponentially with rising vibrational excitation. Intramolecular energy flow between the excited C-H bonds occurring on a subpicosecond timescale is responsible for the bond dissociation.

S/C/X-대역 GaN 저잡음 증폭기 MMIC (A S/C/X-Band GaN Low Noise Amplifier MMIC)

  • 한장훈;김정근
    • 한국전자파학회논문지
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    • 제28권5호
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    • pp.430-433
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    • 2017
  • 본 논문은 0.25 um GaN HEMT 공정을 이용하여 S/C/X-대역에서 저항 피드백 구조의 저잡음 증폭기 MMIC에 관한 연구이다. GaN 소자는 높은 항복 전압과 에너지 밴드갭 그리고 고온에서 안정성을 갖는 고출력 소자로서 장점을 가진다. 따라서 높은 선형성을 가지는 GaN 소자를 이용한 수신기는 리미터 없이 구현할 수 있기 때문에 수신기의 잡음 지수가 개선되고, 수신기 모듈의 크기를 줄일 수 있다. 제안한 GaN 저잡음 증폭기 MMIC는 S/C/X-대역에서 15 dB 이상의 이득, 3 dB 이하의 잡음 지수, 13 dB 이상의 입력 반사 손실, 그리고 8 dB 이상의 출력 반사 손실을 가진다. GaN 저잡음 증폭기 MMIC는 드레인 전압 20 V, 게이트 전압 -3 V일 때, 70 mA의 전류를 소모한다.