• Proceedings of the Korean Society of Precision Engineering Conference
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• 2009.06a
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• pp.1031-1032
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• 2009

• Korean Journal of Pharmacognosy
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• v.45 no.1
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• pp.88-92
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• 2014

Lysimachia foenum-graecum (LF) has been used for home remedy of common cold and headache in China. Foenumoside B from LF has been reported for anti-obesity effects. We used foenumoside B as a marker for content evaluation of different parts of LF. Ethanol extract of LF was used for isolation of foenumoside B and purified further by column chromatography. The structure was identified as foenumoside B by interpretation of spectroscopic analysis, including $^1H$-, $^{13}C$-NMR and FT-ICR-MS. High-performance liquid chromatography (HPLC) method was used to compare the quantitative level of foenumoside B in different parts of LF. Foenumoside B contents in the leaf, stem, and aerial part showed significant differences. Contents of foenumoside B was detected highly in the leaf extracts. The results would be useful for efficient extraction of foenumoside B in LF.

• Biomolecules & Therapeutics
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• v.17 no.4
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• pp.430-437
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• 2009

Metabolites of Soyasaponin I, a major constituent of soybean, by human intestinal microflora were investigated by LC-MS/MS analysis. We found four peaks, one parental constituent and three metabolites: m/z 941 [M-H]$^-$, m/z 795 [M-rha-H]$^-$, m/z 441 [aglycone-$H_2O$+H]$^+$, and m/z 633 [M-rha-gal-H]$^-$, which was an unknown metabolite, soyasapogenol B 3-$\beta$-D-glucuronide. When soyasaponin I was incubated with the human fecal microbial fraction from ten individuals for 48 h, soyasaponin I was metabolized to soyasapogenol B via soyasaponin III and soyasapogenol B 3-$\beta$-D-glucuronide or via soyasaponin III alone. Both soyasaponin I and its metabolite soyasapgenol B exhibited estrogenic activity. Soyasaponin I increased the proliferation, mRNA expression of c-fos and pS2, in MCF7 cells more potently than soyasapogenol B. However, soyasapogenol B showed potent cytotoxicity against A549, MCF7, HeLa and HepG2 cells, while soyasaponin I did not. The cytotoxicity of soyasapogenol B may prevent its estrogenic effect from increasing dose-dependently. These findings suggest that orally administered soyasaponin I may be metabolized to soyasapogenol B by intestinal microflora and that soyasapogenol B may express a cytotoxic effect rather than an estrogenic effect.

• Proceedings of the Korean Society of Precision Engineering Conference
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• 2008.06a
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• pp.345-346
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• 2008

• Proceedings of the KIEE Conference
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• 1999.07e
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• pp.2164-2166
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• 1999

This paper is describes the measured electric field waveform radiated by lightning discharge. We have performed measurement and analysis of the electric fields associated with stepped leaders. Electric field measurement system was composed of hemisphere electric field sensor, measurement system of a distance from lightning strokes, automatical recording system, A/D board, personal computer etc. A/D board have high sampling time, high speed data processing, 8bit of resolution. Also, measured characteristics of stepped leaders radiated by were analyzed.

• Mass Spectrometry Letters
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• v.4 no.4
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• pp.67-70
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• 2013

The Cu-binding site in the $[Cu{\cdot}dCMP{\cdot}dCMP-H]^{1-}$ complex was investigated. The tandem mass (MS/MS) spectra of the [$[Cu{\cdot}dCMP{\cdot}dCMP-H]^{1-}$ parent ion showed $[dCMP{\cdot}Cu{\cdot}H_2PO_4+CONH]^{1-}$ fragment ions. Therefore, we propose that the Cu cation is simultaneously coordinated to the phosphate site and cytosine moiety in the stable geometry of the $[Cu{\cdot}dCMP{\cdot}dCMP-H]^{1-}$ complex. Three geometries for the complex were considered in an attempt to optimize the structure of the $[Cu{\cdot}dCMP{\cdot}dCMP-H]^{1-}$ complex. The ab initio calculations were performed at the $B3LYP/6-311G^{**}$ level.

• Proceedings of the KSME Conference
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• 2003.04a
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• pp.1748-1753
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• 2003

3D-PTV measurement was conducted on the wake of a sphere. The Reynolds number is 1130 with the diameter(d=30mm). The measurement system consisted of three CCD cameras, an image grabber, an Ar-Ion laser and a host computer. An eigenvalue analysis was introduced for the analysis on the wake. Statistical turbulent properties were quantitatively clarified using the time-consecutive instantaneous three-dimensional vectors obtained by the 3D-PTV system. The spatial distributions of the sphere wake showed strong relations with spiral motions of the vortcies shedded from the surface of the sphere.

• Transactions of the Korean Society of Mechanical Engineers B
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• v.24 no.8
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• pp.1046-1055
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• 2000

The flow and thermal phenomena in flat tubes of radiator are analyzed numerically. To predict the characteristics of heat transfer and pressure drop, the flow analysis program for three-dimensional complex geometry is developed, which adopted an non-staggered grid system and Cartesian velocities as dependent variables of the momentum equations. Using the developed program, the effect of tube specifications on the heat transfer characteristics is investigated for various flat tubes. From this study, the following results are obtained; (1) For the same hydraulic diameter($D_h{\doteq}5.2$mm), the Nusselt numbers of three basic modeis(D, J, and H-model) are 8.71, 8.92, and 10.58, respectively, and the pressure drops of D-, J-, and H-model are predicted as $-3.08{\times}10^{-2}\;Pa,\;-3.12{\times}10^{-2}\;Pa,\;and\; -3.98{\times}10^{-2}$ Pa, (2) In case of the same flat tube specification, the fins must be brazed at upper tube surface because the heat is more vividly transferred. Therefore, it is found that the H- model is the most effective tube as a heat exchanger and these results are used as a fundamental data for the design of tube.

• Proceedings of the Korean Society of Precision Engineering Conference
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• 2012.10a
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• pp.737-738
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• 2012

• Proceedings of the Korean Society of Precision Engineering Conference
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• 2013.05a
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• pp.1257-1258
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• 2013