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Study on Contents Comparison of Foenumoside B in Different Parts of Lysimachia foenum-graecum  

Um, Young Ran (Pharmaceutical R&D center, Kolmar Korea Co., Ltd.)
Mok, So Youn (Pharmaceutical R&D center, Kolmar Korea Co., Ltd.)
Shin, Jae-Hyuck (Pharmaceutical R&D center, Kolmar Korea Co., Ltd.)
Kim, Seul-Ki (Pharmaceutical R&D center, Kolmar Korea Co., Ltd.)
Cho, Byoung-Heon (Pharmaceutical R&D center, Kolmar Korea Co., Ltd.)
Cho, Yong Baik (Pharmaceutical R&D center, Kolmar Korea Co., Ltd.)
Publication Information
Korean Journal of Pharmacognosy / v.45, no.1, 2014 , pp. 88-92 More about this Journal
Abstract
Lysimachia foenum-graecum (LF) has been used for home remedy of common cold and headache in China. Foenumoside B from LF has been reported for anti-obesity effects. We used foenumoside B as a marker for content evaluation of different parts of LF. Ethanol extract of LF was used for isolation of foenumoside B and purified further by column chromatography. The structure was identified as foenumoside B by interpretation of spectroscopic analysis, including $^1H$-, $^{13}C$-NMR and FT-ICR-MS. High-performance liquid chromatography (HPLC) method was used to compare the quantitative level of foenumoside B in different parts of LF. Foenumoside B contents in the leaf, stem, and aerial part showed significant differences. Contents of foenumoside B was detected highly in the leaf extracts. The results would be useful for efficient extraction of foenumoside B in LF.
Keywords
Lysimachia foenum-graecum; Foenumoside B; HPLC;
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