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The Effects of Corneal Eccentricity and Shape on Toric Soft Lens Rotation by Change of Postures (이심률 및 각막형상이 자세변화에 의한 토릭소프트렌즈의 회전에 미치는 영향)

  • Kim, So Ra;Hahn, Shin Woong;Song, Ji Soo;Park, Mijung
    • Journal of Korean Ophthalmic Optics Society
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    • v.18 no.4
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    • pp.449-456
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    • 2013
  • Purpose: The present study aimed to investigate the effects of corneal eccentricity and shape on the rotational pattern of toric soft lens by the postural change of lens wearers. Methods: The corneal eccentricity of 41 eyes (aged 20s) having -1.0 D with-the-rule corneal astigmatism (WRCA) was measured, and then toric soft lenses were fitted with the amount of total astigmatism. In lying and straight postures, the rotation of toric soft lenses was recorded by a camera attached to slitlamp and analyzed. Results: Most toric soft lens designed with accelerated stabilization rotated to the temporal direction, which was the lying position direction, regardless of corneal eccentricity, and some lenses rotated to the nasal direction for high corneal eccentricity and corneal type of asymmetric bowtie. There was no correlation between the amount of rotation and corneal eccentricity right after of contact lens wearing in straight and lying posture, however, the amount of rotation was the greater for the cornea with the higher eccentricity after the subjects laying down for some period. The speed of lens rotation started to decrease after the subjects laying down, but the speed was not different according to corneal eccentricity difference. The amount of lens rotation for symmetric and asymmetric bowtie-typed corneas increased more than it for oval-typed cornea, and it was same even with time elapsing. The speed of lens rotation in lying posture was the slowest in asymmetric bowtie-typed cornea compared with other corneal types. Conclusions: From the present study, it was revealed that the rotational pattern of toric soft lens was affected by corneal eccentricity and corneal shape when the wearer's posture changed. Thus, it should be considered for the development of the fitting guideline and the design of toric soft lens.

Postprandial hypoglycemic effects of mulberry twig and root bark in vivo and in vitro (In vivo와 in vitro에서 상지 및 상백피 에탄올추출물이 식후 혈당 상승 억제 조절에 미치는 영향)

  • Park, Soo Yeon;Jin, Bo Ra;Lee, Yu Rim;Kim, You Jin;Park, Jeong Bin;Jeon, Young Hee;Choi, Sang Won;Kwon, Oran
    • Journal of Nutrition and Health
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    • v.49 no.1
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    • pp.18-27
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    • 2016
  • Purpose: Our previous study demonstrated the hypoglycemic effects of mulberry (Morus alba L.) leaf and the underlying mechanisms. Here we explored the potency of mulberry twigs (TW) and root barks (RB) in postprandial hypoglycemic effects in vitro and in vivo. Methods: The major components of TW and RB were determined by high performance liquid chromatography (HPLC). Alpha-glucosidase inhibition and glucose/fructose uptake inhibition in Caco-2 cells were determined for TW, RB, and their major components, followed by an oral sugar tolerance test (OSTT) in streptozotocin-induced diabetic rats. Male Wistar rats were fed a high-fat diet for 2 weeks and then a single dose of streptozotocin (35 mg/kg B.W) was administered by intraperitoneal injection. Rats with fasting blood glucose levels above 126 mg/dL were randomly divided into 5 groups (n = 8/group) for the following treatments by gavage for 4 weeks: vehicle (normal control and diabetic control), 200 mg/kg B.W of TW or RB or 100 mg/kg B.W of oxyresveratrol (OXY). Results: OXY and mulberroside A were identified as the major components of TW and OXY, mongolicin, and kuwanon H for RB. A significant inhibitory activity on ${\alpha}-glucosidase$ was found for TW, RB, and OXY (p = 0.0099). There was a dose-dependent inhibition of TW and RB on the intestinal sugar uptakes in Caco-2 cells, showing a greater impact on fructose compared to glucose. The OSTT showed that TW and RB significantly delayed time to maximal concentration (p = 0.0088) and decreased maximal concentration (p = 0.0043) compared to the control group. Conclusion: These results suggest that TW and RB may have a postprandial hypoglycemic effect, particularly in the case of high fructose or sucrose intake. OXY was suggested as a contributor to the hypoglycemic effect of TW and RB. Further studies are needed for the systemic effect of TW and RB in circulation.

Technical Review of Target Volume Delineation on the Posterior Fossa Tumor : An Optimal Head and Neck Position (후두와 종양의 방사선치료 시 표적용적의 결정을 위한 적절한 치료자세 연구)

  • Yoon Sang Min;Lee Sang-wook;Ahn Seung Do;Kim Jong Hoon;YE Byong Yong;Ra Young Shin;Kim Tae Hyung;Choi Eun Kyung
    • Radiation Oncology Journal
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    • v.21 no.1
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    • pp.94-99
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    • 2003
  • Purpose : To explore a 3D conformal radiotherapy technique for a posterior fossa boost, and the potential advantages of a prone position for such radiotherapy. Materials and Methods :A CT simulator and 3D conformal radiotherapy Planning system was used for the posterior fossa boost treatment on a 13-year-old medulloblastoma patient. He was placed In the prone position and Immobilized with an aquaplast mask and immobilization mold. CT scans were obtained of the brain from the top of the skull to the lower neck, with IV contrast enhancement. The target volume and normal structures were delineated on each slice, with treatment planning peformed using non-coplanar conformal beams. Results : The CT scans, and treatment In the prone position, were peformed successfully. In the prone position, the definition of the target volume was made easier due to the well enhanced tentorium, In audition, the posterior fossa was located anteriorly, and with the greater choice of beam arrangements, more accurate treatment planning was possible as the primary beams were not obstructed by the treatment table. Conclusion : .A posterior fossa boost, in the prone position, Is feasible in cooperating patients, but further evaluation is needed to define the optimal and most comfortable treatment positions.

Radiation-induced Apoptosis in Developing Fetal Rat Cerebral Cortex (발육 중의 백서 태아 대뇌 피질에서 방사선에 의한 아포토시스)

  • Chung Woong-Ki;Nam Taek-Kehn;Lee Min-Cheol;Ahn Sung-Ja;Song Ju-Young;Park Seung-Jin;Nah Byung-Sik
    • Radiation Oncology Journal
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    • v.21 no.4
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    • pp.315-321
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    • 2003
  • Purpose: This study was peformed to Investigate apoptosis by radiation In the developing fetal rat brain. Materials and Methods: Fetal blains were Irradiated In utero between the 17th and 19th days of fetal life (El7-19) by linear accelerator. A dose of Irradiation ranging from 1 Gy to 4 Gy was used to evaluate dose dependency. To test time dependency the ra)s were Irradiated with 2 Gy and then the fetal brain specimens were removed at variable 41me course; 1, 3, 5, 12 and 24 hours after the onset of irradiation. Immunohistochemlcal staining using in situ 707-mediated dUTP nick end labelling (TUNEL) technlfue was used for apoptotic cells. The cerebral cortex, including three zones on coriicai zone (Cf). Intermediate zone (if), and ventricular zone (VZ), was examined. Results : TUNEL positive cells revealed typical features of apoptotic cells under light microscope In the fetal rat cerebral cortex. Apoptotic cells were not found In the cerebral cortex of non-Irradiated fetal rats, but did appear In the entire cerebral cortex after 1 Gy Irradiation, and were more expensive at the ventricular and Intermediate zones than at the cortical zone. The extent of apoptosis was Increased with Increasing doses of radiation. Apoptosis reached the peak at S hours after the onset of 2 Gy Irradiation and persisted until 24 hours. Conclusion: Typical morphological features of apoplosis by irradiation were observed In the developing fetal rat cerebral cortex. It was more extensive at the ventricular and Intermediate zones than at the cortical zone, which suggested that stem cells or early differentiated cells are more radiosensitive than differentiated cells of the cortical zone.

Evaluation of titanium surface properties by $Nd:YVO_4$ laser irradiation: pilot study ($Nd:YVO_4$ 레이저 조사에 따른 티타늄의 표면특성 평가: 예비 연구)

  • Kim, Ae-Ra;Park, Ji-Yoon;Kim, Yeon;Jun, Sei-Won;Seo, Yoon-Jeong;Park, Sang-Won
    • The Journal of Korean Academy of Prosthodontics
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    • v.51 no.3
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    • pp.167-174
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    • 2013
  • Purpose: This study was conducted to evaluate the roughness and surface alternations of three differently blasted titanium discs treated by $Nd:YVO_4$ Laser irradiation in different conditions. Materials and methods: Thirty commercially pure titanium discs were prepared and divided into three groups. Each group was consisted of 10 samples and blasted by $ZrO_2$ (zirconium dioxide), $Al_2O_3$ (aluminum oxide), and RBM (resorbable blasted media). All the samples were degreased by ultrasonic cleaner afterward. Nine different conditions were established by changing scanning speed (100, 300, 500 mm/s) and repetition rate (5, 15, 35 kHz) of $Nd:YVO_4$ Laser (Laser Pro D-20, Laserval $Korea^{(R)}$, Seoul, South Korea). After laser irradiation, a scanning electron microscope, X-ray diffraction analysis, energy dispersive X-ray spectroscopic analysis, and surface roughness analysis were used to assess the roughness and surface alternations of the samples. Results: According to a scanning electron microscope (SEM), titanium discs treated with laser irradiation showed characteristic patterns in contrast to the control which showed irregular patterns. According to the X-ray diffraction analysis, only $Al_2O_3$ group showed its own peak. The oxidation tendency and surface roughness of titanium were similar to the control in the energy dispersive X-ray spectroscopic analysis. The surface roughness was inversely proportional to the scanning speed, whereas proportional to the repetition rate of $Nd:YVO_4$. Conclusion: The surface microstructures and roughness of the test discs were modified by the radiation of $Nd:YVO_4$ laser. Therefore, laser irradiation could be considered one of the methods to modify implant surfaces for the enhancement of osseointegration.

The Study to Re-establish the Amount and Major Pollution Source of Wastewater from Seasonal Swine Farms (양돈농가에서의 계절별 세정수 발생량 및 주요 오염원 재설정 연구)

  • Kwag, J.H.;Choi, D.Y.;Kim, J.H.;Jeong, K.H.;Cho, S.H.;Jeong, M.S.;Kang, H.S.;Ra, C.S.
    • Journal of Animal Environmental Science
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    • v.15 no.3
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    • pp.225-230
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    • 2009
  • The purpose of this study was to determine the effect of re-establish the amount and major pollution source of swine wastewater from swine farms. The results obtained in this study was summarized as follow; The quantity of wastewater produced from the average volume of swine wastewater was $2.49{\ell}$/head/day and $2.49{\ell}$ in spring, $2.65{\ell}$ in summer, $2.47{\ell}$ in autumn, and $2.35{\ell}$ in winter. The quantity of wastewater production during summer season was higher than of the other seasons. The water pollutant concentration in wastewater of swine farms, $BOD_5$, SS, T-N and T-P, was $4,689\;mg/{\ell}$, $2,122\;mg/{\ell}$, $3,238\;mg/{\ell}$ and $118\;mg/{\ell}$, respectively.

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Vertical Profiles and Assessment of Trace Metals in Sediment Cores From Outer Sea of Lake Shihwa, Korea (시화호 외측 해역 주상 퇴적물 내 미량금속 수직분포 특성 및 오염도 평가)

  • Ra, Kongtae;Kim, Joung-Keun;Kim, Eun-Soo;Kim, Kyung-Tae;Lee, Jung-Moo;Kim, Eu-Yeol
    • Journal of the Korean Society for Marine Environment & Energy
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    • v.16 no.2
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    • pp.71-81
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    • 2013
  • Trace metal concentration in sediment cores from the outer sea of Lake Shihwa were determined to study the vertical profiles of metal concentrations and to evaluate the levels of metal contamination. Sediment pollution assessment was carried out using enrichment factor (EF) and geo-accumulation index (Igeo). The mean concentration of metals were 58.8 mg/kg for Cr, 10.3 mg/kg for Co, 22.8 mg/kg for Ni, 18.1 mg/kg for Cu, 74.0 mg/kg for Zn, 6.75 mg/kg for As, 0.14 mg/kg for Cd, 27.4 mg/kg for Pb and 0.026 mg/kg for Hg, respectively. The mean EF values for Cu, Zn, As, Cd and Hg were greater than 1.5 in sediment cores, indicating that these metals in sediments are slightly enriched by anthropogenic activities. The geo-accumulation index (Igeo) suggested unpolluted status for metals of sediments collected from outer see of Lake Shihwa. Igeo values for Cu and Hg nearby LNG station (site C, D, E) ranged from 1 to 2, indicating moderately to unpolluted pollution status for those metals. Even if the higher concentrations of trace metals nearby LNG station were observed, there is significantly positive relationship between Al and trace metals. Thus, the sediment grain size plays an important roles in influencing the distribution of trace metals in sediment cores from the outer sea of Lake Shihwa. Based on the comparison with sediment quality guidelines such as threshold effect level and probable effect level in Korea, the concentration of metals in sediments from outer sea of Lake Shihwa are likely to result in no harmful effects on sediment-dwelling organisms.

Effects of Fermented Feedstuff with Wet Brewer’s Grain and Soybean on Fattening Performance and Carcass Grade in hanwoo Steers (맥주박 발효사료 및 대두의 급여가 한우 거세우의 육성성적 및 도체등급에 미치는 영향)

  • Park, B.K.;Gil, J.M.;Kim, J.B.;Hong, B.J.;Ra, C.S.;Shin, J.S.
    • Journal of Animal Science and Technology
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    • v.45 no.3
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    • pp.397-408
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    • 2003
  • This study was conducted to examine the feeding effects of FFWBG (fermented feedstuff with wet brewer’s grain) and GS(grinding soybean) in Hanwoo steers. For this research, total twenty steers(average body weight : 455.7$\pm$25.9kg) were grouped into control(formula feed), T1(formula feed:FFWBG=60:40), T2(formula feed:GS=80:20), T3(formula feed:FFWBG:GS=50:40:10), and T4(formula feed: FFWBG:GS=40:40:20), each treatment was allocated to four steers. There was a tendency to be increased average daily gain in T1, T2, T3 and T4 compared with the control even though no statistical significance was found. The feed conversion of T1, T2, T3 and T4 were beneficially better than that of control(P<0.05; 8.25, 9.44, 6.69 and 7.71 vs 11.90, respectively). The blood urea nitrogen concentration of T4 was higher than that of control(P<0.05), but the creatinine concentration of T4 was lower than that of control(P<0.05). The glucose concentration of T1, T2, T3 and T4 were higher than that of control(P<0.05; 59.39, 62.44, 62.17 and 54.00 vs 51.00mg/$d\ell$, respectively). The back-fat thickness of T3 was thicker than that of control, T1, T2 and T4. The rib-eye area of T1, T3 and T4 was wider than that of control. Appearances percentage of ‘A’ ranked meat quantity were 66, 33, 75 and 33% in control, T1, T2 and T4, respectively.

Microwave Irradiation as a Way to Reutilize the Recovered Struvite Slurry and to Enhance System Performance (회수된 MAP 슬러리의 재이용과 공정효율 향상을 위한 도구로서의 극초단파 조사)

  • Cho, Joon-Hee;Lee, Jin-Eui;Ra, Chang-Six
    • Journal of Animal Science and Technology
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    • v.51 no.4
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    • pp.337-342
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    • 2009
  • The feasibility of reutilization of magnesium ammonium phosphate (MAP) or struvite slurry recovered from the process through microwave irradiation was studied in this experiment. For this purpose, 4 different operations were performed with or without Mg source addition and different levels of MAP recycled in a batch reactor. Dissolution rate of MAP, ${NH_4}^+$ elimination pattern and physicochemical changes of MAP during microwave irradiation were also studied. The result showed that only 33% orthophosphate ($PO_4-P$) and 27% $NH_4-N$ removal occurred without adding any external Mg source (run A), whereas 87% $PO_4-P$ and 40% $NH_4-N$ removed when 1.0 M ratio of $MgCl_2$ (run B) was added based on $PO_4-P$ in influent. Although the addition of 1.0 molar ratio of microwave irradiated MAP (Run C) removed lower $PO_4-P$ and $NH_4-N$ than 1.0 M $MgCl_2$ (run B), $PO_4-P$ removal was double when compared with no Mg addition (run A). Addition of half MAP and half $MgCl_2$ (run D) showed the similar removal efficiency (88% $PO_4-P$ and 35% $NH_4-N$) with sole $MgCl_2$ addition (run B). Based on these results, the reutilization of MAP irradiated by microwave would be a feasible way to enhance the removal efficiencies of N and P, as well as curtail the Mg chemical usage. Track study showed that $NH_4-N$ gradually increased at initial stage of microwave irradiation of MAP, and then started eliminating from liquor as temperature increased over $45^{\circ}C$. Dissolution rate of ${PO_4}^{-3}$ during microwave irradiation was proportional to the initial MAP concentration, having $0.0091x^{0.6373}$ mg/sec. It was found from the scanning electron microscope (SEM) study that physical structure of MAP crystal started breaking down into small cube granules within very short time by electromagnetic vibration force during microwave irradiation and then gradually melted down into solution.

A Real-Time Head Tracking Algorithm Using Mean-Shift Color Convergence and Shape Based Refinement (Mean-Shift의 색 수렴성과 모양 기반의 재조정을 이용한 실시간 머리 추적 알고리즘)

  • Jeong Dong-Gil;Kang Dong-Goo;Yang Yu Kyung;Ra Jong Beom
    • Journal of the Institute of Electronics Engineers of Korea SP
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    • v.42 no.6
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    • pp.1-8
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    • 2005
  • In this paper, we propose a two-stage head tracking algorithm adequate for real-time active camera system having pan-tilt-zoom functions. In the color convergence stage, we first assume that the shape of a head is an ellipse and its model color histogram is acquired in advance. Then, the min-shift method is applied to roughly estimate a target position by examining the histogram similarity of the model and a candidate ellipse. To reflect the temporal change of object color and enhance the reliability of mean-shift based tracking, the target histogram obtained in the previous frame is considered to update the model histogram. In the updating process, to alleviate error-accumulation due to outliers in the target ellipse of the previous frame, the target histogram in the previous frame is obtained within an ellipse adaptively shrunken on the basis of the model histogram. In addition, to enhance tracking reliability further, we set the initial position closer to the true position by compensating the global motion, which is rapidly estimated on the basis of two 1-D projection datasets. In the subsequent stage, we refine the position and size of the ellipse obtained in the first stage by using shape information. Here, we define a robust shape-similarity function based on the gradient direction. Extensive experimental results proved that the proposed algorithm performs head hacking well, even when a person moves fast, the head size changes drastically, or the background has many clusters and distracting colors. Also, the propose algorithm can perform tracking with the processing speed of about 30 fps on a standard PC.