• The Transactions of the Korean Institute of Electrical Engineers C
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• v.49 no.3
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• pp.186-195
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• 2000

In this paper, partial discharge (PD) measurement was performed to evaluate the quality of the cable joint and termination constructions. The resistive coupling technique for PD detection using resistivity of semiconducting layer of the cable in the accessories, such as joints and terminations. With high frequency PD (HEPD) measurement, an excellent sensitivity below 20pC could be achieved under unshielded condition. The localization of the defects in the accessories could be identified. During heating cycle, PDs were monitored and analyzed. At that time, the PDs were dependent on the temperature of the heating cycle and showed cyclic behaviors, which were attributed to local delamination of the interfaces, between epoxy unit and stress relief cone(SRC) and between SRC and cable, due to the difference of thermal expansion. As a conclusion, HFPD measurement technique was proven to be an effective diagnostic method for qualification of extra high voltage (EHV) cable accessories. With this technique, the optimal design of the components of the accessories could be verified not only in an early stage but also under operating condition. This technique would result in the improvement of the reliability of the EHV cable accessories.

• Toxicological Research
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• v.17
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• pp.59-69
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• 2001

Arsenic exposure is associated with several human diseases, including cancers, atherosclerosis, hypertension, and cerebrovascular diseases. In cultured cells, arsenite, an inorganic arsenic com-pound, was demonstrated to interfere with many physiological functions, such as enhancement of oxidative stress, delay of cell cycle progression, and induction of structural and numerical changes of chromosomes. The objective of this study is to investigate the effects of arsenic exposure on gene expression profiles by colorimetric cDNA microarray technique. HFW (normal human diploid skin fibroblasts), CL3 (human lung adenocarcinoma cell line), and HaCaT (immortalized human keratinocyte cell line) were treated with 5 $\mu\textrm{M}$ or 10 $\mu\textrm{M}$ sodium arsenite for 6 or 16 h, respectively. By a dual-color detection system, the expression profile of arsenite-treated cultures was compared to that of control cultures. Several genes expressed differentially were identified on the microarray membranes. For example, MDM2, SWI/SNF, ubiquitin specific protease 4, MAP3K11, RecQ protein-like 5, and Ribosomal protein Ll0a were consistently induced in all three cell types by arsenite, whereas prohibitin, cyclin D1, nucleolar protein 1, PCNA, Nm23, and immediate early protein (ETR101) were apparently inhibited. The present results suggest that arsenite insults altered the expression of several genes participating in cellular responses to DNA damage, stress, transcription, and cell cycle arrest.

• Journal of the Korean Institute of Illuminating and Electrical Installation Engineers
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• v.28 no.10
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• pp.56-62
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• 2014

When fault currents contain decaying DC offset, the peak value of the fault current in the first cycle of the fault period is higher than the fault current during the steady-state period. To reduce the asymmetric fault current, this paper proposes an operation scheme using the series connection of two hybrid type Superconducting Fault Current Limiters (SFCLs) : an auxiliary SFCL and a main SFCL. The proposed method calculates the fault angle by comparing the zero-crossing time with fault detection time. According to the fault angle calculated, an auxiliary SFCL operates to reduce an asymmetric fault current during half a cycle after fault occurrence. After this process, the fault current is limited by a main SFCL. To confirm the usefulness of the proposed method, case studies using Electro-Magnetic Transients Program (EMTP)/Alternative Transient Program (ATP) Draw are perfomed.

• Asian Pacific Journal of Cancer Prevention
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• v.15 no.1
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• pp.93-100
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• 2014

Background: Curcumin has has been reported to exert anti-inflammatory, anti-oxidation and anti-angiogenic activity in various types of cancer. It has also been shown to induce apoptosis in leukemia cells. We aimed to unravel the role of the redox pathway in Curcumin mediated apoptosis with a panel of human leukemic cells. Materials and Methods: In this study in vitro cytotoxicity of Curcumin was measured by MTT assay and apoptotic effects were assessed by annexin V/PI, DAPI staining, cell cycle analysis, measurement of caspase activity and PARP cleavage. Effects of Curcumin on intracellular redox balance were assessed using fluorescent probes like $H_2DCFDA$, JC1 and an ApoGSH Glutathione Detection Kit respectively. Results: Curcumin showed differential anti-proliferative and apoptotic effects on different human leukemic cell lines in contrast to minimal effects on normal cells. Curcumin induced apoptosis was associated with the generation of intracellular ROS, loss of mitochondrial membrane potential, intracellular GSH depletion, caspase activation. Conclusions: As Curcumin induces programmed cell death specifically in leukemic cells it holds a great promise as a future therapeutic agent in the treatment of leukemia.

• Journal of Positioning, Navigation, and Timing
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• v.6 no.4
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• pp.149-157
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• 2017

In this study, a system that precisely determines the heave of ship hull was designed using time-differenced GNSS carrier phase measurement, and the performance was examined. First, a technique that calculates precise position relative to the original position based on TDCP measurement for point positioning using only one receiver was implemented. Second, to eliminate the long-cycle drift error occurring due to the measurement error that has not been completely removed by time-differencing, an easily implementable high-pass filter was designed, and the optimum coefficient was determined through an experiment. In a static experiment based on the precise heave measurement system implemented using low-cost commercial GNSS receiver and PC, the heave could be measured with a precision of 2 cm standard deviation. In addition, in a dynamic experiment where it moved up and down with an amplitude of 48 cm and a cycle of 20 seconds, precise heave without drift error could be determined. The system proposed in this study can be easily used for many applications, such as the altitude correction of fish detection radar.

• Journal of the Earthquake Engineering Society of Korea
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• v.6 no.5
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• pp.29-36
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• 2002

In the maintenance and retrofit planning of a bridge system, the optimal strategy for inspection and repair are suggested by minimizing the expected total life-cycle cost, which includes the initial cost, the costs of inspection, repair, and failure. Degradation of seismic performance is modeled by using a damage function. And failure probability is computed according to the degree of damage detection by random vibration theory and the event tree analysis. As an example to illustrate the proposed approach, a 10-span continuous bridge structure is used. The numerical results show that the optimum number of the inspection and the repair are increased, as the seismic intensity is increased and the soil condition of a site becomes more flexible.

• Journal of Korean Society of Industrial and Systems Engineering
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• v.33 no.3
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• pp.1-9
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• 2010

To protect information resources, many organizations including private corporate and government employ integrated information security systems which provide the functions of intrusion detection, firewall, and virus vaccine. So, in order to develop a reliable integrated information security system during the development life cycle, the managers in charge of the development of the system must effectively distribute the development resources to the quality factors of an integrated information security system. This study suggests a distribution methodology that minimizes the total cost with satisfying the minimum quality level of an integrated information security system by appropriately assigning development resources to quality factors considered. To achieve this goal, we identify quality factors of an integrated information system and then measure the relative weights among the quality factors using analytic hierarchy process (AHP). The suggested distribution methodology makes it possible to search an optimal solution which minimizes the total cost with satisfying the required quality levels of processes by assigning development resources to quality factors during the development life cycle.

• Korean Journal of Environmental Agriculture
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• v.39 no.1
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• pp.26-35
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• 2020

BACKGROUND: Microbes that govern a unique biochemical process of oxidizing ammonia into dinitrogen gas, such as anaerobic ammonium oxidation (anammox) have been reported to play a pivotal role in agricultural soils and in oceanic environments. However, limited information for anammox bacterial abundance and distribution in the terrestrial habitats has been known. METHODS AND RESULTS: Phylogenetic and next-generation sequencing analyses of bacterial 16S rRNA gene were performed to examine potential anammox bacteria in paddy soils. Through clone libraries constructed by using the anammox bacteria-specific primers, some clones showed sequence similarities with Planctomycetes (87% to 99%) and anammox bacteria (94% to 95%). Microbial community analysis for the paddy soils by using Illumina Miseq sequencing of 16S rRNA gene at phylum level was dominated by unclassified Bacteria at 33.2 ± 7.6%, followed by Chloroflexi at 20.4 ± 2.0% and Acidobacteria at 17.0 ± 6.5%. Planctomycetes that anammox bacteria are belonged to was 1.5% (± 0.3) on average from the two paddy soils. CONCLUSION: We suggest evidence of anammox bacteria in the paddy soil. In addition to the relatively well-known microbial processes for nitrogen-cycle, anammox can be a potential contributor on the cycle in terrestrial environments such as paddy soils.

• Journal of Korean Institute of Industrial Engineers
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• v.40 no.1
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• pp.43-51
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• 2014

Statistical process control (SPC) is an important technique for monitoring and managing the manufacturing process. In spite of its easiness and effectiveness, some problematic sides of application exist such that the SPC techniques are hardly reflect the changes of the process conditions. Especially, update of control limits at the right time plays an important role in acquiring a reasonable performance of control charts. Therefore, we propose the control chart performance evaluation index (CPEI) based on count data model to monitor and manage the performance of control charts. The CPEI could indicate the degree of control chart performance and be helpful to detect the proper update cycle of control limits in real time. Experiments using real manufacturing data show that the proper update intervals are made by proposed method.

• The Journal of the Acoustical Society of Korea
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• v.41 no.4
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• pp.446-460
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• 2022

In this paper, we propose an algorithm to improve target detection rate degradation due to direct blast in a bi-static sonar systems with high duty cycle using an adaptive filters. It is very important to suppress the direct blast in the aforementioned sonar systems because it has a fatal effect on the actual system operation. In this paper, the performance was evaluated by applying the Normalized Least Mean Square (NLMS) and Recursive Least Square (RLS) algorithms to the simulation and sea experimental data. The beam signals of the target and direct blast bearings were used as the input and desired signals, respectively. By optimizing the difference between the two signals, the direct blast is removed and only the target signal is remained. As a result of evaluating the results of the matched filter in the simulation, it was confirmed that the direct blast was removed to the noise level in both Linear Frequency Modultated (LFM) and Generalized Sinusoidal Frequency Modulated (GSFM), and in the case of GSFM, the target sidelobe decreased by more than 20 dB, thereby improving performance. In the sea experiment, it was confirmed that the LFM reduced the level of the transmitted direct wave by 10 dB, the GSFM reduced the level of the transmitted direct wave by about 4 dB, and the side lobe of the target decreased by about 4 dB, thereby improving the performance.