• Asian Pacific Journal of Cancer Prevention
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• v.16 no.14
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• pp.6123-6128
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• 2015

Background: The aim of this study was to analyze the prognostic implications of pretreatment circulating endothelial cells (CECs) and circulating endothelial progenitor cells (CEPCs) for the survival of patients with lung cancer. Materials and Methods: Relevant literature was identified using Medline and EMBASE. Patient clinical characteristics, overall survival (OS) and progression-free survival (PFS) together with CEC and CEPC positive rates before treatment were extracted. STATA 12.0 was used for our analysis and assessment of publication bias. Results: A total of 13 articles (8 for CEC and 5 for CEPC, n=595 and n=244) were pooled for the global meta-analysis. The odds ratio (OR) for OS predicted by pretreatment CECs was 1.641 [0.967, 2.786], while the OR for PFS was 1.168 [0.649, 2.100]. The OR for OS predicted by pretreatment CEPCs was 12.673 [5.274, 30.450], while the OR for PFS was 4.930 [0.931, 26.096]. Subgroup analyses were conducted according to clinical staging. Odds ratio (OR) showed the high level of pretreatment CECs only correlated with the OS of patients with advanced lung cancer (stage III-IV). Conclusions: High counts of CECs seem to be associated only with worse 1-year OS in patients with lung cancer, while high level of pretreatment CEPCs correlate with both worse PFS and OS.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.16 no.11
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• pp.8030-8036
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• 2015

This study is to explore the effect of figure and color informations on assessing expressed emotions in drawings. A pilot study was conducted to explore emotional responses to achromatic drawing stimuli. The main experiment explored emotional responses to chromatic drawing stimuli. Each experiment has a number of 50, 56 participants separately, and responses included joy, depression, and anger according to appraisal-potency-activity dimensions. As results, achromatic drawing stimuli with their texture and rhythm produced specific emotions in high rates. Moreover, response rates of specific emotions were lower when colors added, or emotional responses were changed with colors. The significance of this study can be found in the fact that it dealt with colors combined with shape, unlike the previous studies, and that the experiments were conducted under more controlled conditions in terms of stimulus presentation and response management.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.15 no.5
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• pp.3046-3050
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• 2014

The purpose of the present study was to evaluate the effect of 7-point interval scale(EAI) and visual analogue scale(VAS) on perceptual judgement and the reliability of severity on voice problems by dysphonic speakers. 30 undergraduate students studying communication disorder were enrolled in the perceptual evaluation. Those listeners judged overall voice severity within the anchored(condition 1) and non-anchored scales(condition 2) for vowel prolongation and reading tasks by 25 speakers with voice disorder. The results of this study showed that the scores by VAS was significantly higher than EAI in both condition 1 and condition 2 for vowel prolongation and reading task. However, the scores by EAI method was higher than by VAS method on voice severity of vowel prolongation (condition 1) and reading task(condition 2). These results suggest auditory-perceptual scaling procedures must be more studied in the aspects of clinical application of voice disorder.

• Perspectives in Nursing Science
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• v.16 no.1
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• pp.1-11
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• 2019

Purpose: This study was conducted to identify the perceptions toward school forest programs related to forest welfare services in elementary schools and suggest strategies to activate new programs. Methods: A mixed method research was performed. Four teachers and one forest therapist participated in a focus group interview; 162 teachers answered a survey. Results: The teachers were aware of the effects of the forest program, but there were some barriers, including the question of whether there was an accessible forest, school forest management problems, the risk of teachers' work overload, and the lack of program diversification for elementary students. Solutions included the expansion of school forests and forest facilities available to students, development of a variety of programs, provision of appropriate information on available facilities, and cooperation with educational institutions for institutionalization and increased effectiveness of school-based forest utilization programs. In addition, a scientific basis for data accumulation is needed. Conclusion: The Ministry of Forestry is cooperating with the Ministry of Education and local education offices to activate a forest-use health promotion program for elementary school students. Additionally, to utilize the forests in regular education courses, teachers should strive to spread positive awareness of forests.

• Journal of Music and Human Behavior
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• v.15 no.2
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• pp.23-39
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• 2018

The purpose of this research was to investigate the effects of respiratory rehabilitation using a wind instrument for patients suffering from spinal cord injuries. From January 15, 2018 to April 15, 2018, we conducted ten 1-hour sessions of a harmonica program with eight patients with spinal cord injuries with average age of 37 years who could not perform abdominal breathing by themselves. We measured and compared patients' breathing capacity before and after the 10 sessions. Designed particularly for patients with spinal cord injuries resulting in a limited range of neck movement, the study used a 10-hole diatonic harmonica whose length was relatively short. For those patients who had difficulty using their hands, a harmonica holder was provided. Participants were trained to play simple tunes. They were guided to use abdominal breathing to make sounds, with emphasis on those parts requiring long and strong breathing. The results showed that for all eight patients both their breathing volume and their inspiratory volume increased following participation in the harmonica program. Also, the program had psychological benefits (e.g., more life satisfaction and less sadness) and additional physical benefits (e.g., less dizziness due to low blood pressure and better phlegm spitting). This study offers a unique way to help patients with spinal cord injuries to improve their breathing capacity, which may also be associated with a greater quality of life.

• Radiation Oncology Journal
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• v.29 no.1
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• pp.28-35
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• 2011

Purpose: Recently, the use of radiosurgery as a local therapy in patients with early stage non-small cell lung cancer has become favored over surgical resection. To evaluate the efficacy of radiosurgery, we analyzed the results of stereotactic body radiosurgery in patients with primary or recurrent non-small cell lung cancer. Materials and Methods: We reviewed medical records retrospectively of total 24 patients (28 lesions) with non-small cell lung cancer (NSCLC) who received stereotactic body radiosurgery (SBRT) at Inha University Hospital. Among the 24 patients, 19 had primary NSCLC and five exhibited recurrent disease, with three at previously treated areas. Four patients with primary NSCLC received SBRT after conventional radiation therapy as a boost treatment. The initial stages were IA in 7, IB in 3, IIA in 2, IIB in 2, IIIA in 3, IIIB in 1, and IV in 6. The T stages at SBRT were T1 lesion in 13, T2 lesion in 12, and T3 lesion in 3. 6MV X-ray treatment was used for SBRT, and the prescribed dose was 15~60 Gy (median: 50 Gy) for PTV1 in 3~5 fractions. Median follow up time was 469 days. Results: The median GTV was 22.9 mL (range, 0.7 to 108.7 mL) and median PTV1 was 65.4 mL (range, 5.3 to 184.8 mL). The response rate at 3 months was complete response (CR) in 14 lesions, partial response (PR) in 11 lesions, and stable disease (SD) in 3 lesions, whereas the response rate at the time of the last follow up was CR in 13 lesions, PR in 9 lesions, SD in 2 lesions, and progressive disease (PD) in 4 lesions. Of the 10 patients in stage 1, one patient died due to pneumonia, and local failure was identified in one patient. Of the 10 patients in stages III-IV, three patients died, local and loco-regional failure was identified in one patient, and regional failure in 2 patients. Total local control rate was 85.8% (4/28). Local recurrence was recorded in three out of the eight lesions that received below biologically equivalent dose 100 $Gy_{10}$. Among 20 lesions that received above 100 $Gy_{10}$, only one lesion failed locally. There was a higher recurrence rate in patients with centrally located tumors and T2 or above staged tumors. Conclusion: SBRT using a CyberKnife was proven to be an effective treatment modality for early stage patients with NSCLC based on high local control rate without severe complications. SBRT above total 100 $Gy_{10}$ for peripheral T1 stage patients with NSCLC is recommended.

• Progress in Medical Physics
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• v.25 no.4
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• pp.264-270
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• 2014

This study developed a portable respiratory training device to improve breathing stability, which is an important element in using the CyberKnife Synchrony respiratory tracking device, one of the typical Stereotactic Radiation Therapy (SRT) devices. It produced an interface for users to be able to select one of two displays, a graph type and a bar type, supported an auditory system that helps them expect next respiration by improving a sense of rhythm of their respiratory period, and provided comfortable respiratory inducement. By targeting 5 applicants and applying individual respiratory period detected through a self-developed program, it acquired signal data of 'guide respiration' that induces breathing through signal data gained from 'free respiration' and an auditory system, and evaluated the usability by comparing deviation average values of respiratory period and respiratory amplitude. It could be identified that respiratory period decreased $55.74{\pm}0.14%$ compared to free respiration, and respiratory amplitude decreased $28.12{\pm}0.10%$ compared to free respiration, which confirmed the consistency and stability of respiratory. SBRT, developed based on these results, using the portable respiratory training device, for liver cancer or lung cancer, is evaluated to be able to help reduce delayed treatment time due to respiratory instability and improve treatment accuracy, and if it could be applied to developing respiratory training applications targeting an android-based portable device in the future, even use convenience and economic efficiency are expected.

• The Journal of the Korea Contents Association
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• v.14 no.9
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• pp.362-370
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• 2014

This study measured and analyzed the correlation coefficient between movements of thoracoabdominal tumors and external respiration in a free-breathing state, using cyberknife image guided radiotherapy(IGRT). This study subjects included a total of 30 patients with lung tumors(n=10), liver tumors(n=10) and pancreatic tumor(n=10) who underwent radiotherapy, and the movements of tumors were analyzed using converted log data of the tumor motion tracking system(MTS). In a free-breathing state, In relation to Peason's correlation coefficient between external respiration and lung tumors in the entire treatment process, the correlation coefficient was 0.646(p<0.05) in the cranio-caudal direction, 0.365(p<0.088) in the left and right direction and 0.196(p<0.115) in the antero-posterior direction. The correlation coefficient of liver tumors was 0.841(p<0.000) in the cranio-caudal direction, 0.346 (p<0.179) in the left and right direction and 0.691(p<0.001) in the antero-posterior direction. The correlation coefficient of Pancreatic tumors was 0.683(p<0.000) in the cranio-caudal direction, 0.397(p<0.006) in the left and right direction and 0.268(p<0.127) in the antero-posterior direction. In conclusion, the measurement findings of thoracoabdominal tumor movement using IGRT would be helpful in determining an accurate target volume. Moreover, the analysis of correlation between external respiration and movements of internal tumors would provide important information to correct movements of tumors for diverse radiotherapy techniques.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.12 no.7
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• pp.3149-3155
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• 2011

The purpose of this study was to know the characteristics of DDK performance between CV(e.g. 'pa') and VV(e.g., 'ai') syllables in typically developing children aged 4 to 6 years old. 12 TD children performed DDK with CV structure(/pʰə/, /tʰə/, /kʰə/, /pʰətʰə/, /tʰəkʰə?/, /pʰətʰəkʰə/) and with VV structure(/ai/, /ɔi/, /ɑɔi/). Spoken syllables were counted in one second, and all spoken DDK were measured by PC-quirer. The results showed that all spoken DDK became faster as the age of children were increased. This trend was also appeared in both CV and VV syllables repetition. In addition, there was no differences in DDK rate with CV and VV syllables. The frequency of articulatory error during DDK performance was very high in the age of 3, and there was no pattern in the frequency of articulatory error according to the developmental age.

• Journal of Digital Policy
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• v.1 no.2
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• pp.71-77
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• 2022

The purpose of this study is to analyze the job satisfaction of hospital workers according to the type of hospital and to provide basic data for successful hospital management. For data analysis, frequency analysis and chi-square analysis are performed for general characteristics, and Kendall's tau correlation analysis is performed to see the correlation between statistically significant factors among job environment, value realization, organizational characteristics, and individual ability factors. did A total of 241 people working at primary, secondary, and tertiary medical institutions were surveyed. Among the value realization factors in the research results, self-esteem and rewarding (p<0.05), autonomy and creativity (p<0.05), and among personal competencies factors, workload (p<0.05) were statistically A significant difference was seen. Value realization and personal competence factors were found to influence job satisfaction (p<0.001). In conclusion, the most basic for the qualitative and quantitative growth of the hospital should be the job satisfaction of the internal members, on the basis of which positive medical services should be provided to the patients.