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http://dx.doi.org/10.5392/JKCA.2014.14.09.362

Analysis of Correlation Coefficient Between Movements of Thoracoabdominal Tumors and External Respiration Using Image Guided Radiotherapy(IGRT)  

Kim, Gha-Jung (극동대학교 방사선학과)
Hong, Ju-Youn (충북대학교 대학원 의학과 의료정보학 및 관리학교실)
Han, Sang-Hyun (서남대학교 방사선학과)
Publication Information
The Journal of the Korea Contents Association / v.14, no.9, 2014 , pp. 362-370 More about this Journal
Abstract
This study measured and analyzed the correlation coefficient between movements of thoracoabdominal tumors and external respiration in a free-breathing state, using cyberknife image guided radiotherapy(IGRT). This study subjects included a total of 30 patients with lung tumors(n=10), liver tumors(n=10) and pancreatic tumor(n=10) who underwent radiotherapy, and the movements of tumors were analyzed using converted log data of the tumor motion tracking system(MTS). In a free-breathing state, In relation to Peason's correlation coefficient between external respiration and lung tumors in the entire treatment process, the correlation coefficient was 0.646(p<0.05) in the cranio-caudal direction, 0.365(p<0.088) in the left and right direction and 0.196(p<0.115) in the antero-posterior direction. The correlation coefficient of liver tumors was 0.841(p<0.000) in the cranio-caudal direction, 0.346 (p<0.179) in the left and right direction and 0.691(p<0.001) in the antero-posterior direction. The correlation coefficient of Pancreatic tumors was 0.683(p<0.000) in the cranio-caudal direction, 0.397(p<0.006) in the left and right direction and 0.268(p<0.127) in the antero-posterior direction. In conclusion, the measurement findings of thoracoabdominal tumor movement using IGRT would be helpful in determining an accurate target volume. Moreover, the analysis of correlation between external respiration and movements of internal tumors would provide important information to correct movements of tumors for diverse radiotherapy techniques.
Keywords
Image Guided Radiation Therapy; Movements of Thoracoabdominal Tumors; CyberKnife $Synchrony^{TM}$; Respiration Tracking;
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