• Clinical and Experimental Pediatrics
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• v.58 no.6
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• pp.199-205
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• 2015

Severe aplastic anemia (SAA) is a life-threatening disorder for which allogeneic hematopoietic stem cell transplantation (HSCT) is the current available curative treatment. HSCT from matched sibling donors (MSDs) is the preferred therapy for children with acquired SAA. For patients who lack MSDs, immunosuppressive therapy (IST) is widely accepted as a first-line treatment before considering HCT from an unrelated donor (URD). Given the recent progress in HSCT using URDs for childhood SAA, well-matched URDs became a realistic alternative for pediatric patients who have no suitable related donors and who are refractory to IST. However, it is quite challenging to treat patients with refractory SAA who lack suitable related or URDs. Even though haploidentical HSCT from genetically mismatched family members seemed to be an attractive procedure with the amazing benefit of readily available donors for most patients, early attempts were disappointing because of refractory graft-versus-host disease (GVHD) and excessively high transplant-related mortality. Recent advances with effective ex vivo depletion of T cells or unmanipulated in vivo regulation of T cells, better supportive care, and optimal conditioning regimens have significantly improved the outcome of haploidentical transplant. Besides considerable progress in the treatment of malignant diseases, recent emerging evidences for haploidentical HSCT in SAA has provided additional therapeutic options for patients with refractory diseases. Further improvements to decrease the rates of graft failure, GVHD, and infectious complications will facilitate the emergence of haploidentical HSCT as a front-line therapy for treating acquired SAA in children and adolescents who have no suitably matched donors.

• Journal of Power System Engineering
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• v.22 no.1
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• pp.41-47
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• 2018

This paper analyzes the output characteristics of a self excited induction generator with isolated mode according to change of its speeds and loads for building a hybrid electric propulsion system in special purpose ships by using power take off. The induction generators are being considered as an alternative choice to the well-developed generators because of their lower unit cost, inherent ruggedness, operational and maintenance simplicity. However, the generator working by stand alone has a few problems that the reactive power is required to establish the air gap magnetic flux, and the induced voltage and magnetizing current fluctuate when the load is varied. In spite of its advantages, basic design data of the capacitor bank and behaviors of the output characteristics of the generator are not sufficient for the system. Based on the operating condition(speed range of main engine) of the target boat, a reduced experimental equipment system was constructed to analyze the output characteristics of the SEIG. And a suitable capacitor bank of a stand-alone generator and its output characteristics under various loads was investigated in detail through these experiments. According to the experimental result, it was confirmed that the capacitor bank should be $70{\mu}F{\sim}100{\mu}F$, and the proper SEIG induced voltage should be DC 80 V ~ 250 V in order to storage electrical energy into a battery.

• Proceedings of the SAREK Conference
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• 2008.11a
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• pp.413-418
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• 2008

The toroidal field magnet power supply (TF MPS) for the KSTAR was constructed in August, 2007 and started the operation for the commissioning in March, 2008. The main role of the TF MPS is to supply the electric power to the TF magnet of the KSTAR. The water cooling components of the TF MPS are 16 stacks, busbar of 70 meters. For the cooling of the TF MPS, the D I water cooling system was designed and installed. The water cooling system consists of several pumps, heat exchangers, D I water polishing system and so on. The water cooling system for the TF MPS was tested under the 15 kA current charging condition. In this paper be discussed about the system performance and other parameters.

• Proceedings of the SAREK Conference
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• 2008.11a
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• pp.340-344
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• 2008

The importance of the more efficient cogeneration system is emphasized. Also the more clean energy is needed at recent energy system. The cogeneration system using Lean burn engine is more preferred to the system using Rich burn engine because of the electrical efficiency. Although the cogeneration system using Lean burn engine is economically preferred, because of the NOx emission level, the system using Rich burn engine with 3-way catalyst can only be used in Korea. The NOx regulation level is 50ppm at oxygen level 13%. The cogeneration hybrid system using Lean burn engine is up to be optimized because of the large amount of the extra-fuel at the after-burner system. The after-burner system at different concept was applied. The reduction time for the activation temperature of the DeNOx catalyst was achieved by making a hole between the combustor and boiler. Because of the lowered fuel consumption, the lowered temperature level was optimized by blocking the hole of the boiler The optimized cogeneration hybrid system consumes $76Nm^3/h$ LNG to produce 150kW electricity compared to before optimization $103Nm^3/h$ LNG. The system was accurately evaluated and the result is following ; 90% total efficiency, below 10 ppm NOx, 50ppm CO, 25ppm HC. The cogeneration hybrid system can meet the current NOx level and exhaust gas regulation. It can achieve the clean combustion gas and efficient cogeneration system.

• Journal of Korean Society of Rural Planning
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• v.26 no.2
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• pp.117-126
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• 2020

In this study, demands of smart technology development were analyzed for rural village communities. Questionnaire items were derived by grasping the current status of information and communication technology. 49 villages in 8 regions were selected and surveys and statistical analysis were conducted. The main results of the study are as follows. First, 92% of community leaders use smartphones, search for information (38%), communicate with the Internet (36%) using smartphones, use KakaoTalk (31%), and Facebook (24%). Second, in the rural and urban exchange activities, promote support information service (51%) and promote method suggestion service (48.5%) showed that the demand for services in promote field was high. It is linked to the creation of economic opportunities. Third, in the income and production activities, demand for distribution services technology (39.3%) was high in the field of production and distribution, and cold chains that help maintain freshness until food, such as meat, fish, and vegetables are delivered to consumers when agricultural products are distributed. The constant temperature control system needs to be actively introduced. Fourth, autonomy activities showed the highest demand for air conditioning and control systems (34.2%) of community building, and the lowest demand for electronic voting (9.4%) and videoconferencing (9.4%) services. Lastly, in the general activity area of the community, the demand for technology of emergency services (37.1%) and health self-diagnosis service (35.4%), which are technologies in the welfare sector, ranked first and second respectively.

• Journal of Power Electronics
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• v.17 no.4
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• pp.1037-1047
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• 2017

The Differential Power Processing (DPP) converter is a promising multi-module photovoltaic inverter architecture recently proposed for photovoltaic systems. In this paper, a DPP converter architecture, in which each PV-panel has its own DPP converter in shunt, performs distributed maximum power point tracking (DMPPT) control. It maintains a high energy conversion efficiency, even under partial shading conditions. The system architecture only deals with the power differences among the PV panels, which reduces the power capacity of the converters. Therefore, the DPP systems can easily overcome the conventional disadvantages of PCS such as centralized, string, and module integrated converter (MIC) topologies. Among the various types of the DPP systems, the feed-forward method has been selected for both its voltage balancing and power transfer to a modified H-bridge inverter that needs charge balancing of the input capacitors. The modified H-bridge multi-level inverter had some advantages such as a low part count and cost competitiveness when compared to conventional multi-level inverters. Therefore, it is frequently used in photovoltaic (PV) power conditioning system (PCS). However, its simplified switching network draws input current asymmetrically. Therefore, input capacitors in series suffer from a problem due to a charge imbalance. This paper validates the operating principle and feasibility of the proposed topology through the simulation and experimental results. They show that the input-capacitor voltages maintain the voltage balance with the PV MPPT control operating with a 140-W hardware prototype.

• Proceedings of the SAREK Conference
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• 2006.06a
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• pp.554-559
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• 2006

The currently common housing is obviously going to be under the reconstruction in just $20{\sim}30$ years, with the failure to satisfy the improvement of national income, diversification and advance of national demand. But, reckless and random reconstruction Induce the serious problem of environmental pollution involving the loss of national treasury and excess materials of constructions. In order to address such problem, the common housing of longevity, which can adequately cope with the changes of times and tastes of inhabiters, in the future, is arising as an alternative. Recently, the groundbreaking phase of common housing is also being considered as another alternative to resolve such problem. The common housing of longevity has an advantage to create a free and comfortable space in accordance with the tastes of inhabiters, as well as expanding the durability of building. But, the current facility system has an inability to deal with the sort of housing. Thus, the research paper is designed to make an analysis on problems of common housing in South Korea, which has made it difficult to handle a changing space, and based on the analysis, the paper is intended to make a review on the future-oriented facility service appropriate enough to deal with the changing aspects of space.

• Proceedings of the SAREK Conference
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• 2006.06a
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• pp.68-73
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• 2006

The present paper deals with an experimental study of boiling heat transfer characteristics of R-290, and is focused on pressure gradient and heat transfer coefficient of the refrigerant flow inside horizontal smooth minichannel with inner diameter of 3.0 mm and length of 2000 mm. The direct heating method applied for supplying heat to the refrigerant where the test tube was uniformly heated by electric current which was applied to the tube wall. The experiments were conducted with R-290 with purity of 99.99% at saturation temperature of 0 to $10^{\circ}C$. The range of mass flux is $50{\sim}250kg/m^2s$ and heat flux is $5{\sim}20kW/m^2$. The heat transfer coefficients of R-290 increases with increasing mass flux and saturation temperature, wherein the effect of mass flux is higher than that of the saturation temperature, whereas the heat flux has a low effect on increasing heat transfer coefficient. The significant effect of mass flux on heat transfer coefficient is shown at high quality, the effect of heat flux on heat transfer coefficient at low quality shows a domination of nucleate boiling contribution. The heat transfer coefficient of the experimental result was compared with six existing heat transfer coefficient correlation. Zang et al.'s correlation(2004) gave the best prediction of heat transfer coefficient.

• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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• 2014.10a
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• pp.845-847
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• 2014

In recent years, the mobile OS market, enlargement and, at the same time, Android has mounted various smart phones and feature air conditioning, smart TV, cleaning robot, camera, etc. that the number is being spread at a rapid pace. But a lot of devices to control the modules and applications at once, this is not a device for controlling the dissemination of applications all in one place, and in charge of the devices that allow you to manage applications are lacking. Accordingly, in this paper, use the Web Server registered in the appliance can be controlled by management, Web access, is proposing and designing the system. This is the current research is actively in progress in the field of IoT (Internet of Things) would be utilized.

• Archives of Plastic Surgery
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• v.48 no.6
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• pp.703-713
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• 2021

The field of vascularized composite allografts (VCAs) has undergone significant advancement in recent decades, and VCAs are increasingly common and accepted in the clinical setting, bringing hope of functional recovery to patients with debilitating injuries. A major obstacle facing the widespread application of VCAs is the side effect profile associated with the current immunosuppressive regimen, which can cause a wide array of complications such as infection, malignancy, and even death. Significant concerns remain regarding whether the treatment outweighs the risk. The potential solution to this dilemma would be achieving VCA tolerance, which would allow recipients to receive allografts without significant immunosuppression and its sequelae. Promising tolerance protocols are being studied in kidney transplantation; four major trials have attempted to withdraw immunosuppressive treatment with various successes. The common theme in all four trials is the use of radiation treatment and donor cell transplantation. The knowledge gained from these trials can provide valuable insight into the development of a VCA tolerance protocol. Despite similarities, VCAs present additional barriers compared to kidney allografts regarding tolerance induction. VCA donors are likely to be deceased, which limits the time for significant pre-conditioning. VCA donors are also more likely to be human leukocyte antigen-mismatched, which means that tolerance must be induced across major immunological barriers. This review also explores adjunct therapies studied in large animal models that could be the missing element in establishing a safe and stable tolerance induction method.