• Journal of Ginseng Research
• /
• v.45 no.1
• /
• pp.66-74
• /
• 2021

Background: Abnormal chloride (Cl-) transport has a detrimental impact on mucociliary clearance in both cystic fibrosis (CF) and non-CF chronic rhinosinusitis. Ginseng is a medicinal plant noted to have anti-inflammatory and antimicrobial properties. The present study aims to assess the capability of red ginseng aqueous extract (RGAE) to promote transepithelial Cl- secretion in nasal epithelium. Methods: Primary murine nasal septal epithelial (MNSE) [wild-type (WT) and transgenic CFTR-/-], fisher-rat-thyroid (FRT) cells expressing human WT CFTR, and TMEM16A-expressing human embryonic kidney cultures were utilized for the present experiments. Ciliary beat frequency (CBF) and airway surface liquid (ASL) depth measurements were performed using micro-optical coherence tomography (μOCT). Mechanisms underlying transepithelial Cl- transport were determined using pharmacologic manipulation in Ussing chambers and whole-cell patch clamp analysis. Results: RGAE (at 30㎍/mL of ginsenosides) significantly increased Cl- transport [measured as change in short-circuit current (ΔISC = ㎂/㎠)] when compared with control in WT and CFTR-/- MNSE (WT vs control = 49.8±2.6 vs 0.1+/-0.2, CFTR-/- = 33.5±1.5 vs 0.2±0.3, p < 0.0001). In FRT cells, the CFTR-mediated ΔISC attributed to RGAE was small (6.8 ± 2.5 vs control, 0.03 ± 0.01, p < 0.05). In patch clamp, TMEM16A-mediated currents were markedly improved with co-administration of RGAE and uridine 5-triphosphate (8406.3 +/- 807.7 pA) over uridine 5-triphosphate (3524.1 +/- 292.4 pA) or RGAE alone (465.2 +/- 90.7 pA) (p < 0.0001). ASL and CBF were significantly greater with RGAE (6.2+/-0.3 ㎛ vs control, 3.9+/-0.09 ㎛; 10.4+/-0.3 Hz vs control, 7.3 ± 0.2 Hz; p < 0.0001) in MNSE. Conclusion: RGAE augments ASL depth and CBF by stimulating Cl- secretion through CaCC, which suggests therapeutic potential in both CF and non-CF chronic rhinosinusitis.

• Journal of the Korea Academia-Industrial cooperation Society
• /
• v.22 no.3
• /
• pp.587-596
• /
• 2021

Naval battleships have systems to perform special purposes, such as the Command and Fire Control System (CFCS). Some of the this equipment should be equipped with an Uninterruptible Power System (UPS ) to ensure operational continuity and the backup of important data, even during unexpected power outages caused by problems with the ship's power generator. Heavy combat losses can occur if the equipment cannot satisfy the function. Therefore, it is important to design a stable UPS. The battery and Battery Management System (BMS) are two of the most important factors for designing a stable UPS. A power outage will be encountered if the battery and BMS are not stable. The customer will be exposed to abnormal situations, loss of important tactical data, and inability to operate some of the CFCS. As a result, an enhanced safety system should be designed. Thus, this study implemented and verified the improved system in terms of three methods, such as comparative analysis of the batteries, improvement about leakage current of the circuit, and tests of the aggressive environmental resistance to improve the UPS for CFCS.

• KIPS Transactions on Software and Data Engineering
• /
• v.11 no.7
• /
• pp.299-306
• /
• 2022

In recent, sensors embedded in robots, equipment, and circuits have become common, and research for diagnosing device failures by learning measured sensor data is being actively conducted. This failure diagnosis study is divided into a classification model for predicting failure situations or types and a regression model for numerically predicting failure conditions. In the case of a classification model, it simply checks the presence or absence of a failure or defect (Class), whereas a regression model has a higher learning difficulty because it has to predict one value among countless numbers. So, the reason that regression modeling is more difficult is that there are many irregular situations in which it is difficult to determine one output from a similar input when predicting by matching input and output. Therefore, in this paper, we focus on input and output data with periodicity, analyze the input/output relationship, and secure regularity between input and output data by performing sliding window-based input data patterning. In order to apply the proposed method, in this study, current and temperature data with periodicity were collected from MMC(Modular Multilevel Converter) circuit system and learning was carried out using ANN. As a result of the experiment, it was confirmed that when a window of 2% or more of one cycle was applied, performance of 97% or more of fit could be secured.

• Korean Journal of Remote Sensing
• /
• v.38 no.5_2
• /
• pp.725-735
• /
• 2022

Currently, disasters occurring in Korea are characterized by unpredictability and complexity. Due to these features, property damage and human casualties are increasing. Since the initial response process of these disasters is directly related to the scale and the spread of damage, optimal decision-making is essential, and information of the site must be obtained through timely applicable sensors. However, it is difficult to make appropriate decisions because indiscriminate information is collected rather than necessary information in the currently operated Disaster and Safety Situation Office. In order to improve the current situation, this study proposed a framework that quickly collects various disaster image information, extracts information required to support decision-making, and utilizes it. To this end, a web-based display system and a smartphone application were proposed. Data were collected close to real time, and various analysis results were shared. Moreover, the capability of supporting decision-making was reviewed based on images of actual disaster sites acquired through CCTV, smartphones, and UAVs. In addition to the reviewed capability, it is expected that effective disaster management can be contributed if institutional mitigation of the acquisition and sharing of disaster-related data can be achieved together.

• Journal of Appropriate Technology
• /
• v.7 no.2
• /
• pp.196-205
• /
• 2021

As industrial safety increases, various industrial accident prevention technologies using smart factory technology are being studied. However, small and medium enterprises (SMEs), which account for the majority of industrial accidents, are having difficulties in preventing industrial accidents by applying these smart factory technologies due to practical problems. In this study, customized monitoring and warning systems for each type of industrial accident were developed and applied to the actual field. Through this, we demonstrated industrial accident prevention technology through appropriate smart factory technology used by SMEs. A customized monitoring system using vision, current, temperature, and gas sensors was established for the four major disaster types: worker body access, short circuit and overcurrent, fire and burns due to high temperature, and emission of hazardous gas. In addition, a notification method suitable for each work environment was applied so that the monitored risk factors could be recognized quickly, and real-time data transmission and display enabled workers and managers to understand the disaster risk effectively. Through the application and demonstration of these appropriate smart factory technologies, the spread of these industrial safety technologies is to be discussed.

• Korean Journal of Materials Research
• /
• v.32 no.11
• /
• pp.481-488
• /
• 2022

The Cu₂ZnSn(S_xSe_1-x)₄ (CZTSSe) absorbers are promising thin film solar cells (TFSCs) materials, to replace existing Cu(In,Ga)Se₂ (CIGS) and CdTe photovoltaic technology. However, the best reported efficiency for a CZTSSe device, of 13.6 %, is still too low for commercial use. Recently, partially replacing the Zn²⁺ element with a Cd²⁺element has attracting attention as one of the promising strategies for improving the photovoltaic characteristics of the CZTSSe TFSCs. Cd²⁺ elements are known to improve the grain size of the CZTSSe absorber thin films and improve optoelectronic properties by suppressing potential defects, causing short-circuit current (J_sc) loss. In this study, the structural, compositional, and morphological characteristics of CZTSSe and CZCTSSe thin films were investigated using X-ray diffraction (XRD), X-ray fluorescence spectrometer (XRF), and Field-emission scanning electron microscopy (FE-SEM), respectively. The FE-SEM images revealed that the grain size improved with increasing Cd²⁺ alloying in the CZTSSe thin films. Moreover, there was a slight decrease in small grain distribution as well as voids near the CZTSSe/Mo interface after Cd²⁺ alloying. The solar cells prepared using the most promising CZTSSe absorber thin films with Cd²⁺ alloying (8 min. 30 sec.) exhibited a power conversion efficiency (PCE) of 9.33 %, J_sc of 34.0 mA/cm², and fill factor (FF) of 62.7 %, respectively.

• The Journal of Korea Institute of Information, Electronics, and Communication Technology
• /
• v.15 no.4
• /
• pp.223-229
• /
• 2022

In this paper, the ignition trans used in boilers was studied. Regardless of the change in the ignition rod length and the ignition rod gap, the output frequency was measured between 59.5 and 61.3 Hz, and it was found that the low frequency circuit operated normally. When the ignition rod gap changed by 2 to 10 mm, the ignition rod length was measured from 2.8A to 3.45A at 30cm. The ignition rod length was measured from 9.37 A to 14.5 A at 500 cm and from 13.2 A to 32.6 A at 1000 cm. As the ignition rod length and the ignition rod gap increased, the current increased. As a result of measuring the secondary coil output voltage. The ignition rod length was measured from AC 0.84 kV to AC 1.75 kV at 30 cm, AC 1.17 kV to AC 1.944 at 500 cm, and AC 1.4 kV to AC 7.18 kV at 1000 cm. As the ignition rod length and the ignition rod gap increased, the output voltage of the secondary coil also increased. As a result of measuring the output voltage of the ignition trans, the ignition rod length was measured from DC 1.11 kV to DC 1.57 kV at 30cm, DC 2.49 kV to DC 3.72 kV at 500cm, and DC 3.78 kV to DC 9.42 kV at 1000cm, and the power voltage increased as the ignition rod length and interval increased.

• The Journal of the Institute of Internet, Broadcasting and Communication
• /
• v.23 no.2
• /
• pp.157-162
• /
• 2023

Among the failures of photovoltaic power generation facilities, failures caused by surges account for 20% of the total failure rate, and energy emissions of tens to hundreds [A] during power generation and electrical damage to inverters and connection boards lead to electrical safety accidents. In particular, in the case of lightning, an abnormal voltage is induced in an electric circuit to destroy insulation, and the current flowing at this time causes a fire and acts as a factor that accelerates the deterioration of parts. Due to this action, the problem of electrical safety of solar power generation devices spreading from outside the city center to the inside of the city center such as houses, apartments, and government offices is emerging. Since lightning strikes cause both field-based and conducted electrical interference, this effect increases with increasing cable length or conductor loops. In addition, surge damages not only solar modules, inverters and monitoring devices, but also building facilities, which can eventually cause operational shutdown due to fire of the photovoltaic power generation system and consequent financial loss. Therefore, in this paper, a lightning protection system for solar power generation devices is studied for the purpose of reducing property damage and human casualties due to the increase in fire and electrical safety accidents caused by lightning strikes in photovoltaic power generation systems.

• The Journal of The Korea Institute of Intelligent Transport Systems
• /
• v.22 no.6
• /
• pp.114-123
• /
• 2023

With the development of computer vision technology, video sensors such as CCTV are detecting incident. However, most of the current incident have been detected based on existing fixed imaging equipment. Accordingly, there has been a limit to the detection of incident in shaded areas where the image range of fixed equipment is not reached. With the recent development of edge-computing technology, real-time analysis of mobile image information has become possible. The purpose of this study is to evaluate the possibility of detecting expressway emergencies by introducing computer vision technology to dash cam. To this end, annotation data was constructed based on 4,388 dash cam still frame data collected by the Korea Expressway Corporation and analyzed using the YOLO algorithm. As a result of the analysis, the prediction accuracy of all objects was over 70%, and the precision of traffic accidents was about 85%. In addition, in the case of mAP(mean Average Precision), it was 0.769, and when looking at AP(Average Precision) for each object, traffic accidents were the highest at 0.904, and debris were the lowest at 0.629.

• The Korean Journal of Pharmacology
• /
• v.22 no.1 s.38
• /
• pp.24-33
• /
• 1986

To ascertain the existence of various adrenoceptors involved in active transport of sodium in the frog skin and to delineate their physiological roles, the influence of various adrenergic agonists and antagonists on the potential difference (PD), short-circuit current (SCC) and total skin conductance (TSC) of the isolated frog skin of Rana nigromaculata were investigated. PD and SCC were determined with Ussing's technique. Drugs were administered to the serosal side of the skin. Experimental results were summarized as follows: 1. The responses to norepinephrine (NE, $6{\times}10^{-8}-6{\times}10^{-5})M$), phenylephrine (PE, $5{\times}10^{-6}-5{\times}10^{-4}M$) and epinephrine (Epi, $5.5{\times}10^{-7}-5.5{\times}10^{-5}M$) were characterized by marked elevation of PD & SCC in dose-related fashion, but the maximal effect attained by Epi was less than those of NE and PE. 2. These increments of PD & SCC were significantly inhibited by prazosin $(2{\times}10^{-6}M)$, a speciflc ${\alpha}_1$-adrenoceptor blocker. The stimulatory effect on PD & SCC were completely abolished by phenoxybenzamine (PBZ, $3.3{\times}10^{-5}M$), an irreversible ${\alpha}$-adrenoceptor blocking agent. Furthermore, with a larger doses of Epi produced marked decline of PD & SCC after the PBZ pretreatment. 3. Isoproterenol (ISP), a ${\beta}$-adrenoceptor agonist, in concentrations ranging from $5{\times}10^{-7}$ to $5{\times}10^{-6}M$ produced dose-related decrease in PD & SCC, which could be abolished by pretreatment with propranolol $(4{\times}10^{-6}M)$, a specific ${\beta}$-adrenoceptor blocker. It was further noted that the effects of Epi on PD & SCC were markedly potentiated by Propranolol pretreatment. 4. Clonidine as well as guanabenz produced increases in PD & SCC and these effects were inhibited more specifically by prazosin pretreatment than by yohimbine. These results indicated that there exist in the frog skin two distinctive types of adrenoceptors, ${\alpha}$ and ${\beta}$, which roughly corresponds to those in mammals, and that the ${\alpha}$ type of adrenoceptors mediate the stimulation of PD & SCC, whereas ${\beta}$-adrenoceptors mediate the inhibition. However, based on evidence at hand, no conclusion could be drawn on the subtype of ${\alpha}$-adrenoceptors which is involved in the stimulation of sodium transport in the frog skin.