• 제목/요약/키워드: Current bleeding

검색결과 85건 처리시간 0.022초

높은 선형성을 갖는 새로운 구조의 MMIC 저잡음 증폭기 (A High Linearity Low Noise Amplifier Using Modified Cascode Structure)

  • 박승표;어경준;노승창;이문규
    • 한국전자파학회논문지
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    • 제27권2호
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    • pp.220-223
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    • 2016
  • 본 논문에서는 캐스코드(cascode) 구조에 트랜지스터를 추가하여 잡음 특성을 유지하면서 높은 선형성을 갖는 저잡음 증폭기 구조를 제안하고 설계하였다. 제안한 구조는 트랜지스터의 사이즈 최적화를 통해 잡음원을 최소화 했으며, 전류원분리(current bleeding) 효과를 주어 선형성을 개선하였다. 저잡음 특성에 유리한 $0.5{\mu}m$ pHEMT 공정을 이용해 제작된 저잡음 증폭기는 1.8~2.6 GHz의 동작 대역에서 30.8 dBm의 $OIP_3$, 15.0 dB의 이득, 1.1 dB의 NF, 11.6 dB/10.4 dB의 입출력 반사 손실 특성을 보였다.

심방세동 환자의 심율동전환 시행 전·후 warfarin 치료의 적절성 평가 (Evaluation of Peri-procedural Warfarin Therapy Undergoing Cardioversion in Patients with Atrial fibrillation)

  • 문정연;김보람;조은정;조윤숙;한현주;최의근
    • 한국임상약학회지
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    • 제26권3호
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    • pp.201-206
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    • 2016
  • Objective: Direct current cardioversion for atrial fibrillation could be associated with the risk of thromboembolic events. Anticoagulation therapy with warfarin (INR 2.0-3.0) is recommended 3 weeks before and 4 weeks after cardioversion to reduce the risk of thromboembolism. This study evaluated warfarin therapy in pharmacist-managed anticoagulant services (ACS). Methods: This retrospective study was performed in 106 patients with atrial fibrillation from 2012 to 2013. The primary efficacy endpoint was the composite of stroke, transient ischemic attack, myocardial infarction, and cardiovascular death. The primary safety measure was major bleeding. To evaluate the peri-procedural effects of warfarin treatment, we studied whether target INR was maintained, as well as the maintenance period of the therapeutic range. Quality of treatment was measured by time in therapeutic range (TTR) by using the Rosendaal method. Results: There were no thromboembolic events, but TEE examination at time of cardioversion showed a left atrial thrombus in three patients (2.8%). Bleeding complications after cardioversion occurred in 2 patients (1.9%). The average INR value at the time of cardioversion was $2.59{\pm}0.8$, and was within the therapeutic range in 83 patients (78%). Analysis of the patients in whom the value was within the therapeutic range twice consecutively showed that the ratio of TTR was 80% and the therapeutic range was maintained in 67 patients (63%) for an average of 4.90 weeks prior to cardioversion. Similarly, 76 patients (72%) had a stable INR within the therapeutic range for an average of 5.70 weeks and a mean TTR of 83%. Conclusion: Pharmacists significantly contributed to appropriate warfarin treatment with close monitoring during cardioversion. Likewise, active pharmacist monitoring and systemic management should be considered to reduce thromboembolism and bleeding complications in the peri-cardioversion period.

Association between soluble forms of the receptor for advanced glycation end products and periodontal disease: a retrospective study

  • Kim, Keun-Suh;Lee, Yun Jong;Ahn, Soyeon;Chang, Yoon-Seok;Choi, Yonghoon;Lee, Hyo-Jung
    • Journal of the Korean Association of Oral and Maxillofacial Surgeons
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    • 제47권6호
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    • pp.445-453
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    • 2021
  • Objectives: Periodontitis is the most common chronic disease that causes tooth loss and is related to systemic diseases such as cardiovascular disease and diabetes. An objective indicator of the current activity of periodontitis is necessary. Soluble forms of the receptor for advanced glycation end products (sRAGE) are markers that reflect the status of inflammatory diseases. In this study, the relationship between sRAGE and periodontitis was analyzed to determine whether it can be used to diagnose the current state of periodontitis. Patients and Methods: Eighty-four patients without any systemic diseases were diagnosed with periodontitis using three classifications of periodontitis. Demographics and oral examination data such as plaque index (PI), bleeding on probing (BOP) index, and probing pocket depth (PPD) were analyzed according to each classification. In addition, correlation and partial correlation between sRAGE and the values indicating periodontitis were analyzed. Results: In each classification, the level of sRAGE tended to decrease if periodontitis was present or severe, but this change was not statistically significant. sRAGE and periodontitis-related variables exhibited a weak correlation, among which the BOP index showed a relatively strong negative correlation (ρ=-0.20). Based on this, on analyzing the correlation between the BOP index and sRAGE in the group with more severe periodontitis (PPD≥5 mm group, severe group of AAP/CDC [American Academy of Periodontology/Centers for Disease Control and Prevention], periodontitis group of López), the correlation further increased (ρ=-0.23, -0.40, -0.50). Partial correlation analysis of the sRAGE and BOP index showed a stronger negative correlation (ρ=-0.36, -0.55, -0.45). Conclusion: sRAGE demonstrated a tendency to decrease upon increased severity of periodontitis according to the classifications used. Above all, the correlation with the BOP index, which reflects the current state of periodontitis, was higher in the group with severe periodontitis. This indicates that the current status of periodontitis can be diagnosed through sRAGE.

피부질환을 위한 $CO_2$ 레이저의 공극 (1.0mm 및 1.6mm)차이에 따른 동작출력 파형변화에 관한 특성연구 (Special quality research about action output waveform change by gap (1.0mm and 1.6mm) difference of $CO_2$ laser for skin disease)

  • 김휘영
    • 대한전기학회:학술대회논문집
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    • 대한전기학회 2007년도 춘계학술대회 논문집 전기기기 및 에너지변환시스템부문
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    • pp.156-158
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    • 2007
  • Laser wave length can have evaporation effect by absorption because outer skin or tissue of focus is consisted of water almost though absorption of water occurs more than 90% almost in formation thickness of very thin floor Can operate outer skin, steam by floor and correct incision of formation is available. Suture surgical operation is avaliable to vein or lymph system and surgical operation region can dry and see as eye and radish bleeding surgical operation is avaliable Specially, stability of tube both end output about pulse by weight very, this research can cause various curative effect because can reduce bulk and control easily current wave style of medical laser using electric power conversion device of high frequency way. If introduce ZVS (Zero Voltage Switching) or ZVZCS (Zero Voltage and Zero Current Switching), is more profitable because can reduce switching damage Because electric power department of proposed medical laser can do stable soft-switching in wide subordinate extent introducing ZVZCS technique by the first help and control department composes microcontroller, output current waveform user have free form make. Result that experiment because design and manufacture, brought result that improve of 20% than existing equipment, and will be bought to get into superior result if supplement as systematic late.

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피부질환을 위한 $CO_2$ 레이저의 공극차이에 따른 동작출력 변화에 관한 연구 (Special quality research about action output waveform change by gap (1.0mm and 1.6mm) difference of $CO_2$ laser for skin disease)

  • 김휘영
    • 대한전기학회:학술대회논문집
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    • 대한전기학회 2007년도 심포지엄 논문집 정보 및 제어부문
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    • pp.52-54
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    • 2007
  • Laser wave length can have evaporation effect by absorption because outer skin or tissue of focus is consisted of water almost though absorption of water occurs more than 90% almost in formation thickness of very thin floor. Can operate outer skin, steam by floor and correct incision of formation is available. Suture surgical operation is available to vein or lymph system and surgical operation region can dry and see as eye and radish bleeding surgical operation is available. Specially, stability of tube both end output about pulse by weight very, this research can cause various curative effect because can reduce bulk and control easily current wave style of medical laser using electric power conversion device of high frequency way. If introduce ZVS (Zero Voltage Switching) or ZVZCS (Zero Voltage and Zero Current Switching), is more profitable because can reduce switching damage. Because electric power department of proposed medical laser can do stable soft-switching in wide subordinate extent introducing ZVZCS technique by the first help and control department composes microcontroller, output current waveform user have free form make. Result that experiment because design and manufacture, brought result that improve of 20% than existing equipment, and will be bought to get into superior result if supplement as systematic late.

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혈우병 환자의 질병관련 특성과 관리실태 (Treatment and Characteristics Related to Patients with Hemophilia)

  • 강현숙;김원옥;유명철;최진이
    • 근관절건강학회지
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    • 제13권2호
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    • pp.119-129
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    • 2006
  • Purpose: The purpose of this study was to analyze current treatments and characteristics of patients with hemophilia. Method: research design is a descriptive study exploring the current treatments, accompanied disorders, features related to the disease and subjects' social-demographic characteristics. The sample consisted of 218 hemophilia patients registered at Korea Hemophilia Foundation. Results: 80.3% of the subjects were diagnosed of this disease before the age of 10. 64.7% of them had a hemophilia familial history. 74.3% of them had disabilities. Main characters related to the disease were lack of the 8th factor and bleeding tendencies. Levels of severity had significant relationship with the number of hemorrhagic experiences. A common comorbidity found was hepatitis C. A treatment agent frequently use was GREENMONO INJ. and most patients injected it by themselves. 47.7% of the subjects used a dosage of 100 unit, and 45.4% of them injected to once a week. Conclusion: These data will be used as valuable knowledge for planning a patient care and managing their symptoms.

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Drug-Coated Balloon Treatment for De Novo Coronary Lesions: Current Status and Future Perspectives

  • Ae-Young Her;Eun-Seok Shin
    • Korean Circulation Journal
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    • 제54권9호
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    • pp.519-533
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    • 2024
  • The outstanding development in contemporary medicine, highlighted by percutaneous coronary intervention (PCI), was achieved through the adoption of drug-eluting stents (DESs). Although DES is the established therapy for patients undergoing PCI for de novo coronary artery disease (CAD), their drawbacks include restenosis, stent thrombosis, and the requirement for dual antiplatelet therapy (DAPT) with an uncertain duration regarding its optimality. Drug-coated balloon (DCB) treatment leaves nothing behind on the vessel wall, providing the benefit of avoiding stent thrombosis and not necessitating obligatory extended DAPT. After optimizing coronary blood flow, DCB treatment delivers an anti-proliferative drug directly coated on a balloon. Although more evidence is needed for the application of DCB treatment in de novo coronary lesions, recent studies suggest the safety and effectiveness of DCB treatment for diverse conditions including small and large vessel diseases, complex lesions like bifurcation lesions or diffuse or multivessel diseases, chronic total occlusion lesions, acute myocardial infarctions, patients at high risk of bleeding, and beyond. Consequently, we will review the current therapeutic choices for managing de novo CAD using DCB and assess the evidence supporting their concurrent application. Additionally, it aims to discuss future important perspectives.

Retrospective Study on the Flow and Characteristics of Dental Emergency Patients in Chosun University Hospital

  • Lee, Sung-Suk;Kim, Su-Gwan;Oh, Ji-Su;Moon, Seong-Yong;You, Jae-Seek;Yu, Kyoung-Hwan;Jo, Ji-Ho;Park, Jin-Sung;Yang, Wang-Sik;Seo, Dong-Kook
    • Journal of Korean Dental Science
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    • 제8권1호
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    • pp.10-15
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    • 2015
  • Purpose: The aim of the present study is to assess the importance of proper treatment timing for dental emergency patients by characterizing current patient care in the emergency room. Materials and Methods: A retrospective chart review of 3,211 patients who visited the Chosun University Hospital's dental emergency department (Gwangju, Korea) was conducted from January 1, 2011 to May 31, 2014. Information regarding age, gender, onset date, main causes, and diagnoses were collected and analyzed. The main causes were divided into six categories: assault, household/play, sports, traffic, work, and others. Result: Emergency visits were more common for men (69%), and the ratio of males to females was 2.2:1 On average, the major cause was household/play (49.8%), followed by others (18.9%), traffic (16.6%), assault (9.1%), sports (2.9%), and work (2.6%). The most frequent diagnosis on average was dental trauma with 82.4%, followed by infection (10.7%), others (4.7%), and bleeding (2.2%). Conclusion: The main reasons for visits to the dental emergency department are dental trauma, dental infection, bleeding, and others. The most frequent reason for dental emergency patients to visit the emergency department was dental trauma (82.4%).

Percutaneous Dilatational Tracheostomy in a Cardiac Surgical Intensive Care Unit: A Single-Center Experience

  • Vignesh Vudatha;Yahya Alwatari;George Ibrahim;Tayler Jacobs;Kyle Alexander;Carlos Puig-Gilbert;Walker Julliard;Rachit Dilip Shah
    • Journal of Chest Surgery
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    • 제56권5호
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    • pp.346-352
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    • 2023
  • Background: A significant proportion of cardiac surgery intensive care unit (CSICU) patients require long-term ventilation, necessitating tracheostomy placement. The goal of this study was to evaluate the long-term postoperative outcomes and complications associated with percutaneous dilatational tracheostomy (PDT) in CSICU patients. Methods: All patients undergoing PDT after cardiac, thoracic, or vascular operations in the CSICU between January 1, 2013 and January 1, 2021 were identified. They were evaluated for mortality, decannulation time, and complications including bleeding, infection, and need for surgical intervention. Multivariable regression models were used to identify predictors of early decannulation and the complication rate. Results: Ninety-three patients were identified for this study (70 [75.3%] male and 23 [24.7%] female). Furthermore, 18.3% of patients had chronic obstructive pulmonary disease (COPD), 21.5% had history of stroke, 7.5% had end-stage renal disease, 33.3% had diabetes, and 59.1% were current smokers. The mean time from PDT to decannulation was 39 days. Roughly one-fifth (20.4%) of patients were on dual antiplatelet therapy and 81.7% had anticoagulation restarted 8 hours post-tracheostomy. Eight complications were noted, including 5 instances of bleeding requiring packing and 1 case of mediastinitis. There were no significant predictors of decannulation prior to discharge. Only COPD was identified as a negative predictor of decannulation at any point in time (hazard ratio, 0.28; 95% confidence interval, 0.08-0.95; p=0.04). Conclusion: Percutaneous tracheostomy is a safe and viable alternative to surgical tracheostomy in cardiac surgery ICU patients. Patients who undergo PDT have a relatively short duration of tracheostomy and do not have major post-procedural complications.

Bump가 있는 초음속 흡입구 유동장의 수치적 연구 (THE NUMERICAL STUDY ON THE SUPERSONIC INLET FLOW FIELD WITH A BUMP)

  • 김상덕;송동주
    • 한국전산유체공학회지
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    • 제10권3호
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    • pp.19-26
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    • 2005
  • The purpose of this paper is the study on the characteristics of an inlet system with shock/boundary layer interactions by using various types of bumps which are substituted for the conventional bleeding system in supersonic inlet. in this study a comprehensive numerical analysis has been performed to understand the three-dimensional flow field including shock/boundary layer interaction and growth of turbulent boundary layer that might occur around a three-dimensional bump in a supersonic inlet. The characteristics of boundary layer seen in the current numerical simulations indicate the potential capability of a three-dimensional bump to control shock/boundary layer interaction in supersonic inlets.