• Journal of the Korean Geotechnical Society
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• v.19 no.2
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• pp.199-206
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• 2003

Particle-size distribution in soils is one of the most fundamental physical properties of soils. One of the latest developments in the study of particle-size distributions has focused on the use of fractal theories. In this study, the fragmentation fractals were used for determining the characteristics of the particle-size distribution curve. It was shown that the mass-size distribution method was more practical than the cumulative number-size distribution method. From the co-relation between fractal dimensions($D_{tot}$) and the coefficient of uniformity($C_{u}$), there was a sharp increase in fractal dimensions for $C_{u}$<4, but fractal dimension converged the single value for $D_{u}$$\geq$6. Fractal dimensions were affected by small sized particles for $C_{c}$$\geq$3 and large sized particles for $C_{c}$/<3. As a result of the analysis of the influence of the effective size($D_{10}$), it was observed that the changes of $D_{tot}$/ were nominal beyond the effective size.

• Proceedings of the KWS Conference
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• 1995.10a
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• pp.3-20
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• 1995

Development of Real-Time Quality Evaluation of Friction Welding by Acousitc Emission : Report 1 ABSTRACT : According as the friction welding has been increasingly applied in manufacturing various machine components because of its significant economic and technical advantages, one of the important concerns is the reliable quality monitoring method for a good weld quality with both joint strength and toughness in the process of its production. However no reliable nondestructive test method is available at present to determine the weld quality particularly in process of production. So this paper presents an experimental examination and quantitative analysis for the real-time evaluation of friction weld quality by acoustic emission, as a new approach which attempts finally to develop an on-line quality monitoring system design for friction welds using AE techniques. As one of the important results, it was confirmed, through this study, that AE techniques can be reliably applied to evaluating the friction weld qualify with 100% joint strength, as the cumulative AE counts occurring during welding period were quantitatively correlated with reliability at 95% confidence level to the joint strength of welds. Real-Time Evaluation of Automatic Production Quality Control for Friction Welding Machine : Report 2 Abstract : Both in-process quality control and high reliability of the weld is one of the major concerns in applying friction welding to the economical and qualified mass-production. No reliable nondestructive monitoring method is available at present to determine the real-time evaluation of automatic production quality control for friction welding machine. This paper, so that, presents the experimental examinations and statistical quantitative analysis of the correlation between the initial cumulative counts of acoustic emission(AE) occurring during plastic deformation period of the welding and the tensile strength of the welded joints as well as the various welding variables, as a new approach which attempts finally to develop an on-line (or real-time) quality monitoring system and a program for the process of real-time friction welding quality evaluation by initial AE cumulative counts. As one of the important results, it was well confirmed that the initial AE cumulative counts were quantitatively and cubically correlated with reliability of 95% confidence level to the joint strength of the welds, bar-to-bar (SCM4 to SUM31, SCM4 to SUM24L) and that an AE technique using initial AE counts can be reliably applied to real-time strength evaluation of the welded joints, and that such a program of the system was well developed resulting in practical possibility of real-time quality control more than 100% joint efficiency showing good weld with no micro-structural defects.

• Transactions of the Korean Society of Mechanical Engineers
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• v.9 no.6
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• pp.757-766
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• 1985

Both in-process quality control and high reliability of the weld is one of the major concerns in applying friction welding to the economical and qualified mass-production. No reliable nondestructive monitoring method is available at present to determine the real-time evaluation of automatic production quality control for friction welding machine. This paper, so that, presents the experimental examinations and statistical quantitative analysis of the correlation between the initial cumulative counts of acoustic emission(AE) occurring during plastic deformation period of the welding and the tensile strength of the welded joints as well as the various welding variables, as a new approach which attempts finally to develop an on-line (or real-time) quality monitoring system and a program for the process of real-time friction welding quality evaluation by initial AE cumulative counts. As one of the important results, it was well confirmed that the initial AE cumulative counts were quantitatively and cubically correlated with reliability of 95% confidence level to the joint strength of the welds, bar-to-bar (SCM4 to SUM31, SCM4 to SUM24L) and that an AE technique using initial AE counts can be reliably applied to real-time strength evaluation of the welded joints, and that such a program of the system was well developed resulting in practical possibility of real-time quality control more than 100% joint efficiency showing good weld with no micro-structural defects.

• Journal of Microbiology and Biotechnology
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• v.25 no.10
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• pp.1761-1767
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• 2015

Sevenband grouper, Epinephelus septemfasciatus, is becoming an important aquaculture species in Korea. However, viral nervous necrosis disease is a large problem causing mass mortality in sevenband grouper aquaculture. Recombinant protein vaccines are one of the best methods to reduce these economic losses. However, the cell-based expression method mainly produces inclusion bodies and requires additional procedures. In this study, we expressed a recombinant viral coat protein of sevenband grouper nervous necrosis virus (NNV) using a cell-free protein synthesis system. The purified recombinant NNV coat protein (rNNV-CP) was injected into sevenband grouper at different doses followed by a NNV challenge. Nonimmunized fish in the first trial (20 μg/fish) began to die 5 days post-challenge and reached 70% cumulative mortality. In contrast, immunized fish also starting dying 5 days postchallenge but lower cumulative mortality (10%) was observed. Cumulative morality in the second trial with different doses (20, 4, and 0.8 μg/fish) was 10%, 40%, and 50%, respectively. These results suggest that rNNV-CP can effectively immunize sevenband grouper depending on the dose administered. This study provides a new approach to develop a recombinant vaccine against NNV infection for sevenband grouper.

• Journal of Korean Neurosurgical Society
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• v.45 no.5
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• pp.275-283
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• 2009

Objective : We retrospectively analyzed survival, local control rate, and incidence of radiation toxicities after radiosurgery for recurrent metastatic brain lesions whose initial metastases were treated with whole-brain radiotherapy. Various radiotherapeutical indices were examined to suggest predictors of radiation-related neurological dysfunction. Methods : In 46 patients, total 100 of recurrent metastases (mean 2.2, ranged 1-10) were treated by CyberKnife radiosurgery at average dose of 23.1 Gy in 1 to 3 fractions. The median prior radiation dose was 32.7 Gy, the median time since radiation was 5.0 months, and the mean tumor volume was $12.4cm^3$. Side effects were expressed in terms of radiation therapy oncology group (RTOG) neurotoxicity criteria. Results : Mass reduction was observed in 30 patients (65%) on MRI. After the salvage treatment, one-year progression-free survival rate was 57% and median survival was 10 months. Age(<60 years) and tumor volume affected survival rate(p=0.03, each). Acute (${\leq}$1 month) toxicity was observed in 22% of patients, subacute and chronic (>6 months) toxicity occurred in 21 %, respectively. Less acute toxicity was observed with small tumors (<$10cm^3$. p=0.03), and less chronic toxicity occurred at lower cumulative doses (<100 Gy, p=0.004). "Radiation toxicity factor" (cumulative dose times tumor volume of <1,000 Gy${\times}cm^3$) was a significant predictor of both acute and chronic CNS toxicities. Conclusion: Salvage CyberKnife radiosurgery is effective for recurrent brain metastases in previously irradiated patients, but careful evaluation is advised in patients with large tumors and high cumulative radiation doses to avoid toxicity.

• The Journal of Internal Korean Medicine
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• v.43 no.3
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• pp.413-422
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• 2022

Objectives: To investigate the weight loss effect of Gambi-tang in obese and overweight adults. Methods: From September 1, 2016 to December 31, 2021, a retrospective chart analysis was conducted on adult men and women who were prescribed Gambi-tang to address obesity and overweight in the National Medical Center (NMC). Partial analysis by age, obesity (Body Mass Index, BMI), duration of dose, and cumulative dose was also conducted. Results: The weight and BMI of the study subjects showed a significant decrease of more than 5% on average before and after treatment. In an analysis of age, significant differences by age could not be confirmed. In the analysis by obesity level, the effect of reducing weight, body fat, and abdominal fat rates in the obese and highly obese groups was greater than in the normal and overweight groups. There was no significant difference by group in the analysis by dosage period. In the analysis by cumulative dose, the greater the cumulative dose up to 1,800 g, the greater the decrease in weight and body fat. The side effect that patients appealed to the most was misjudgment, but not to a serious extent. Conclusions: Gambi-tang has been shown to be effective in weight and body fat loss for both obese and overweight adult men and women.

• Proceedings of the Korean Society of Precision Engineering Conference
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• 2004.10a
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• pp.166-169
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• 2004

A fatigue test was used to evaluate the fatigue life of an actual structure. The loaded state and the constraint condition of an actual structure must be same as the specimen in order to apply the test results to an actual structure by the specimen. The loaded state and constraint conditions can't be same as the specimen in the actual structure which is complicated. In order to reduce these differences, an actual structure test with a lot of frequencies is need to get a fatigue life curve. Therefore, ten sets of accelerated test units which attached unbalanced mass were composed in this study. Acceleration history about the vibration of an actual structure was acquired. Rainflow counting was used on acceleration history, and the life curve return formula was assumed. The return formula that damage satisfied `1' was acquired in a feedback process by the Miner's rule, which was the linear cumulative damage theory. A conservative fatigue life curve was determined with a return formula to have been presumed by each set. The fatigue life of regular rpm condition was calculated by these conservative fatigue life curves.

• The Korean Journal of Applied Statistics
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• v.27 no.3
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• pp.445-459
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• 2014

As a certain job is repeatedly done by a worker, the outcome comparative to the effort to complete the job gets more remarkable. The outcome may be the time required and fraction defective. This phenomenon is referred to a learning-curve effect. We focus on the parametric modeling of the learning-curve effects on count data using a logistic cumulative distribution function and some probability mass functions such as a Poisson and negative binomial. We conduct various simulation scenarios to clarify the characteristics of the proposed model. We also consider a real application to compare the two discrete-type distribution functions.

• Journal of Industrial Technology
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• v.27 no.B
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• pp.83-89
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• 2007

We studied runoff characteristics of combined sewer overflows in a city while it was raining. The event mean concentration (EMC) of biochemical oxygen demand (BOD), chemical oxygen demand ($COD_{Cr}$), suspended solids (SS), total nitrogen (TN), and total phosphorus (TP) in one of the combined sewer sites in Chuncheon was 63.5-211.6 mg/L, 114.9-523.8 mg/L, 70.3-436.4 mg/L, 6.4-33.0 mg/L, and 1.09-6.81 mg/L, respectively. In another combined sewer, the EMC of BOD, COD, SS, TN, and TP was 42.1-131.4 mg/L, 107.7-256.5 mg/L, 33.7-221.1 mg/L, 7.9-26.4 mg/L, and 1.16-3.91 mg/L, respectively. The ratio of the cumulative pollutant mass and the cumulative discharged volume determined using all parameters (BOD, $COD_{Cr}$, SS, TN, and TP) was over 1.0, which shows the first flush effect. Relationships between flow and loadings of BOD, $COD_{Cr}$, SS, TN, and TP were 0.90, 0.89, 0.88, 0.89, 0.92, respectively. Although the size of two areas was almost same, pollutant concentration and loading were different because of the amount of rainfall, rainfall intensity and basin area.

• Development and Reproduction
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• v.24 no.4
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• pp.277-285
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• 2020

The disease-causing koi herpes virus (KHV), also known as cyprinid herpesvirus-3 (CyHV3), causes mass mortality of koi and carp. Koi (Cyprinus carpio) is a host for KHV, one of 12 virus species in the Alloherpesviridae family. We examined the effects of KHV disease koi (KK), and on koi×red common carp (KR) and red common carp×koi (RK) cross, using a virus challenge test. The infected fish had clinical signs that included gill necrosis and skin lesions. The RK and KR were highly more resistant (cumulative mortality: RK; 6% and KR; 8%) to KHV infection than KK fish (cumulative mortality: 28%). KHV DNA was confirmed in the tissues of all dead fish in groups by use of polymerase chain reaction (PCR), and the presence of the KHV protein in kidney was confirmed by immunohistochemistry. Histological analysis showed severe gill lesions and fusion of the lamellae in KK fish, but less severe damage in RK fish. In immunohistochemistry analysis, the KHV protein localized in the cytoplasm of infected kidney cells of KK, but the cross groups had lower levels of KHV antigen. Our data indicate that the cross groups had increased resistance to KHV disease.