• Title/Summary/Keyword: Crystal Class

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Development of Optical CT and PT using BSO Single Crystal (BSO를 이용한 광CT, PT 개발)

  • Shin, K.H.;Lee, B.K.;Cho, H.K.;Kim, Y.H.;Kim, Y.S.;Park, H.S.
    • Proceedings of the KIEE Conference
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    • 1992.07a
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    • pp.491-494
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    • 1992
  • This paper described the development example of optical CT(Current Transformer) and optical PT (Potential Transformer) which is measurement system of current and voltage of electric power line using Electro-Optic effect and Magneto-Optic effect. We designed the optical CT of 22KV class and 154KV class and an optical PT of 22KV class. And now the filed testing is in progress in a KEPCO's substation.

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Histone Deactylase Inhibitors as Novel Target for Cancer, Diabetes, and Inflammation

  • Singh, Parul;Madhavan, Thirumurthy
    • Journal of Integrative Natural Science
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    • v.6 no.1
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    • pp.57-63
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    • 2013
  • Histone deacetylase (HDACs) is an enzyme family that deacetylates histones and non-histones protein. Availability of crystal structure of HDAC8 has been a boosting factor to generate target based inhibitors. Hydroxamic class is the most studied one to generate potent inhibitors. HDAC class I and class II enzymes are emerging as a therapeutic target for cancer, diabetes, inflammation and other diseases. DNA methylation and histone modification are epigenetic mechanism, is important for the regulation of cellular functions. HDACs enzymes play essential role in gene transcription to regulate cell proliferation, migration and death. The aim of this article is to provide a comprehensive overview about structure and function of HDACs enzymes, histone deacetylase inhibitors (HDACi) and HDACs enzymes as a therapeutic target for cancer, inflammation and diabetes.

New Methods of Producing Copper Sulfate Crystals Using Small-Scale Chemistry(SSC) in Elementary School Science (초등과학에서 미량화학(SSC)을 이용한 황산구리 결정 만들기의 새로운 방법)

  • Han, Sang-Joon;Kim, Sung-Kyu
    • Journal of Environmental Science International
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    • v.17 no.9
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    • pp.981-992
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    • 2008
  • This study examined how to produce new methods of copper (II) sulfate crystallization by using a small-scale chemistry tool such as small-scale reaction surface and petri dish. The making of copper(II) sulfate is included in the 5th grade elementary science textbooks. Various copper(II) compounds were reacted with a 2 M sulfuric acid solution. The result of this study is as follows: Seven small amounts of copper(II) compounds were reacted with a few drops of 2 M sulfuric acid solution at room temperature to make a copper(II) sulfate crystal of triclinic shape. Using the petri dish method, a copper(II) sulfate crystal could be identified within one hour of reacting copper(II) hydroxide, copper(II) carbonate, copper(II) nitrate, copper(II) perchlorate, cupric(II) formate from a few drops of 2 M sulfuric acid solution at room temperature. When using the lap top method for copper(II) perchlorate, cupric formate, a proper crystal could be identified within one hour as well. SSC methods were used for the first time to make a copper sulfate crystal via chemical reaction. We can make a copper(II) sulfate crystal using a simple method which is easier, safer and saves time in class. And since a small quantity of chemicals are being used in SSC chemical methods, waste is greatly reduced. This lessens the amount of environmental problems caused by the experiment. This can be helpful in preserving nature. In addition the cost of chemical and laboratory equipment is greatly reduced because it uses material that we find in our daily lives. There will be continued study of small-scale methods such as improvement of new programs, study and training of teachers, and securing SSC tools. I would like to suggest such as SSC methods are applicable in elementary School Science. I would like it to become a wide spread program.

Study on Ultrasonic Transducer for Non-Destructive Evaluation of Highly Attenuative Material Using PMN-PT Single Crystal (PMN-PT 압전 단결정을 이용한 고감쇠 재료 비파괴 평가용 초음파 탐촉자 연구)

  • Kim, Ki-Bok;Ahn, Bong-Young;Kim, Young-Gil;Park, Sang-Ki;Ha, Jeong-Soo
    • Journal of the Korean Society for Nondestructive Testing
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    • v.27 no.4
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    • pp.313-320
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    • 2007
  • Recently, a new class of single-crystal piezoelectric materials such as lead metanibobate doped with lead titanate (PMN-PT) has been synthesized and were found to further enhance the electro-mechanical coupling factor compared to piezo-ceramic materials. This paper describes fabrication and evaluation of PMN-PT single crystal ultrasonic transducers for contact measurement of stainless steel that is one of the highly attenuative materials. The design conditions for ultrasonic transducer such as front matching layer between test materials and piezo-material and backing materials were investigated based on the simulation results by KLM model. The PMN-PT single crystal ultrasonic transducers with centre frequencies at 1 and 2.25 MHz were fabricated and their performances were evaluated.

Record keeping system of bugs for software quality assurance

  • Mateen, Ahmed;Zhu, Qingsheng;Afsar, Salman
    • International journal of advanced smart convergence
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    • v.8 no.4
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    • pp.207-213
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    • 2019
  • Assistance for the quality assurance management and developers to provide high quality software products. Using a bug record keeping system is exceptionally important in software progress, and it is followed vastly by majority of software producing companies in modern era. Regular application of a bug record keeping system is very helpful in developing software systems. We developed this system which helps the software testing team to keep a complete record of their testing activities during the software testing, also increases your confidence in the software quality, class and worth. Our proposed system offers trouble-free and effortless approaches to acquire desired information about bug, also produces different kinds of reports like summary reports, detailed reports etc. It gives facility to create, delete and update any project. Our developed application system is designed by using visual c# at front end and sql server 2008 management studio express at back end.

The Role of Lozenge in Drosophila Hematopoiesis

  • Koranteng, Ferdinand;Cha, Nuri;Shin, Mingyu;Shim, Jiwon
    • Molecules and Cells
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    • v.43 no.2
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    • pp.114-120
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    • 2020
  • Drosophila hematopoiesis is comparable to mammalian differentiation of myeloid lineages, and therefore, has been a useful model organism in illustrating the molecular and genetic basis for hematopoiesis. Multiple novel regulators and signals have been uncovered using the tools of Drosophila genetics. A Runt domain protein, lozenge, is one of the first players recognized and closely studied in the hematopoietic lineage specification. Here, we explore the role of lozenge in determination of prohemocytes into a special class of hemocyte, namely the crystal cell, and discuss molecules and signals controlling the lozenge function and its implication in immunity and stress response. Given the highly conserved nature of Runt domain in both invertebrates and vertebrates, studies in Drosophila will enlighten our perspectives on Runx-mediated development and pathologies.

Low-threshold Optical Bistability Based on Bound States in the Continuum

  • Kim, Myunghwan;Kim, Sangin;Kim, Soeun
    • Current Optics and Photonics
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    • v.6 no.1
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    • pp.10-14
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    • 2022
  • Low-threshold optical bistability is essential for practical nonlinear optical applications. Many bistable optical devices based on high-quality-factor resonators have been proposed to reduce the threshold intensity. However, demonstrating high-quality-factor resonance requires complex fabrication techniques. In this work, we numerically demonstrate optical bistability with bound states in the continuum in a simple one-dimensional Si photonic crystal. The designed structure supports bound states in the continuum, producing an ultrahigh quality factor without tough fabrication conditions. The threshold intensity of the designed device is 150 MW/cm2 at the optical communication wavelength. This scheme may lead to a new class of nonlinear photonics.

Transfer RNA Acceptor Stem Determinants for Specific Aminoacylation by Class II Aminoacyl-tRNA Synthetases

  • Musier, Karin
    • BMB Reports
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    • v.31 no.6
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    • pp.525-535
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    • 1998
  • A critical step in the faithful translation of genetic information is specific tRNA recognition by aminoacyl-tRNA synthetases. These enzymes catalyze the covalent attachment of particular amino acids to the terminal adenosine of cognate tRNA substrates. In general, there is one synthetase for each of the twenty amino acids and each enzyme must discriminate against all of the cellular tRNAs that are specific for the nineteen noncognate amino acids. Primary sequence information combined with structural data have resulted in the division of the twenty synthetases into two classes. In recent years, several high-resolution co-crystal structures along with biochemical data have led to an increased understanding of tRNA recognition by synthetases of both classes. The anticodon sequence and the amino acid acceptor stem are the most common locations for critical recognition elements. This review will focus on acceptor stem discrimination by class II synthetases. In particular, the results of in vitro aminoacylation assays and site-directed and atomic group mutagenesis studies will be discussed. These studies have revealed that even subtle atomic determinants can provide signals for specific tRNA aminoacylation.

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