• The Plant Pathology Journal
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• 제35권4호
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• pp.330-340
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• 2019

The present study was undertaken to evaluate the integrated effect of zinc (Zn) with other nutrients in managing early blight (EB) disease in tomato. A pot experiment was carried out with basal application of the recommended level of macronutrients [nitrogen, phosphorus and potassium (NPK)] and micronutrients [magnesium (Mg) and boron (B)] in bilateral combination with Zn (2.5 and 5.0 mg/kg) in a completely randomized deigned in replicates. Results revealed that interactive effect of Zn with Mg or B was often futile and in some cases synergistic. Zn with NPK yield synergistic outcome, therefore EB disease was managed significantly (disease incidence: 25% and percent severity index: 13%), which resulted in an efficient signaling network that reciprocally controls nutrient acquisition and uses with improved growth and development in a tomato plant. Thus, crosstalk and convergence of mechanisms in metabolic pathways resulted in induction of resistance in tomato plant against a pathogen which significantly improved photosynthetic pigment, total phenolics, total protein content and defense-related enzymes [superoxide dismutase (SOD), catalase (CAT), peroxidase (POX), polyphenol oxidase (PPO) and phenylalanine ammonia-lyase (PAL)]. The tremendous increase in total phenolics and PAL activity suggesting their additive effect on salicylic acid which may help the plant to systemically induce resistance against pathogen attack. It was concluded that interactive effect of Zn (5.0 mg/kg) with NPK significantly managed EB disease and showed positive effect on growth, physiological and biochemical attributes therefor use of Zn + NPK is simple and credible efforts to combat Alternaria stress in tomato plants.

• 전자공학회논문지C
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• 제36C권7호
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• pp.10-16
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• 1999

본 논문은 FCSR(Freedback Control Swing voltage Reduction) 방식을 이용하여 bus 구동전압을 수백 mV이내로 줄일 수 있는 구동기에 대한 내용을 다루고 있다. 이는 MDL 구조와 같이 대용량, 대단위 bus에서의 전력소모를 줄이기 위한 연구로 FCSR은 dual-line bus와 bus precharging을 기본구조로 채택하고 있다. Bus 환경이 변화함에 따라 일정한 구동전압을 유지하기 위하여 구동기의 크기를 자동적으로 조절할 수 있도록 구동기와 bus를 모델링 하였고 또한 odd mode로 동작하는 이웃하는 선간의 커플링 영향을 평행 전류원으로 모델링하여 선간간섭(crosstalk) 영향을 분석하였다. 현대 0.8um 공정으로 제작된 chip은 bus를 600mV로 구동하도록 설계되었으며 테스트결과 3.3V에서 70Mhz로 동작 가능하다. Hspice 시뮬레이션으로 FCSR은 3.3V에서 250Mhz의 동작이 가능하다.

• Journal of Ginseng Research
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• 제40권2호
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• pp.141-150
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• 2016

Background: Adipocyte-macrophage communication plays a critical role regulating white adipose tissue (WAT) inflammatory gene expression. Because WAT inflammation contributes to the development of metabolic diseases, there is significant interest in understanding how exogenous compounds regulate the adipocyte-macrophage crosstalk. An aqueous (AQ) extract of North American (NA) ginseng (Panax quinquefolius) was previously shown to have strong inflammo-regulatory properties in adipocytes. This study examined whether different ginseng extracts influence adipocyte-macrophage crosstalk, as well as WAT inflammatory gene expression. Methods: The effects of AQ and ethanol (EtOH) ginseng extracts ($5{\mu}g/mL$) on adipocyte and macrophage inflammatory gene expression were studied in 3T3-L1 and RAW264.7 cells, respectively, using real-time reverse transcription polymerase chain reaction. Adipose tissue organ culture was also used to examine the effects of ginseng extracts on epididymal WAT (EWAT) and inguinal subcutaneous WAT (SWAT) inflammatory gene expression. Results: The AQ extract caused significant increases in the expression of common inflammatory genes (e.g., Mcp1, Ccl5, Tnf-${\alpha}$, Nos2) in both cell types. Culturing adipocytes in media from macrophages treated with the AQ extract, and vice versa, also induced inflammatory gene expression. Adipocyte Ppar-${\gamma}$ expression was reduced with the AQ extract. The AQ extract strongly induced inflammatory gene expression in EWAT, but not in SWAT. The EtOH extract had no effect on inflammatory gene expression in either both cell types or WAT. Conclusion: These findings provide important new insights into the inflammo-regulatory role of NA ginseng in WAT.

• 전자공학회논문지
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• 제51권12호
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• pp.46-55
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• 2014

고속 전송로를 위한 PCB(Printed Circuit Board) 설계기술은 꾸준히 발전되고 있으며, 통신 시스템의 대용량화에 맞추어 백플레인(Backplane)에 사용되는 스위치 패브릭 인터페이스(Switch Fabric Interface) 또한 10Gbps 이상의 직렬 인터페이스(Serial Interface)를 사용하도록 표준화가 진행되고 있다. 본 논문에서는 테라급 시스템에서 스위치 패브릭 인터페이스로 11.5Gbps의 직렬링크를 사용하기 위하여, PCB 재질 따른 전송로의 전송거리 별 성능을 비교하고, 비아 스터브(Via Stub)의 길이에 의한 영향 및 누화현상(Crosstalk)에 의한 영향을 시뮬레이션을 수행하여 분석하였다. 시뮬레이션의 결과로 백플레인 보드에 저유전 재질 PCB를 사용함으로써, 전송손실에서 8dB의 개선효과를 얻어 표준에서 정한 -25dB 기준을 만족하는 것을 확인하였다. 또한 비아 스터브 길이에 의한 반사손실의 영향을 분석하여 백드릴(Back-drill)여부를 결정하였으며, 전송신호 간 상호간섭을 최소화하는 이격거리를 검증하였다. 이러한 시뮬레이션의 결과로부터 모든 스위치 패브릭 링크에 11.5Gbps의 직렬 링크를 적용할 수 있도록 가장 효율적인 시스템구조를 확정하였다.

• Journal of Microbiology and Biotechnology
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• 제27권5호
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• pp.1032-1037
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• 2017

The poly-${\gamma}$-$\small{D}$-glutamic acid (PGA) capsule, a major virulence factor of Bacillus anthracis, provides protection of the bacterium from phagocytosis and allows its unimpeded growth in the host. We investigated crosstalk between murine natural killer (NK) cells and macrophages stimulated with the PGA capsule of Bacillus licheniformis, a surrogate of the B. anthracis capsule. PGA induced interferon-gamma production from NK cells cultured with macrophages. This effect was dependent on macrophage-derived IL-12 and cell-cell contact interaction with macrophages through NK cell receptor NKG2D and its ligand RAE-1. The results showed that PGA could enhance NK cell activation by inducing IL-12 production in macrophages and a contact-dependent crosstalk with macrophages.

• 한국전자파학회논문지
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• 제11권3호
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• pp.419-428
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• 2000

전송선 방정식을 이용하여 선형소자로 종단된 손실이 있는 다중 전송선에서의 누화(crosstalk)와 외부 전자파 에 의한 결합현상을 FDTD 기법으로 해석하였다. 표피효과에 의한 도체의 손실을 고려하여 해석할 경우 전송선 방정식에 컨벌루션 적분이 나타나게 되는데 컨벌루션 적분의 계산량을 줄이기 위해서 프로니(Prony) 방법을 이 용하였다. 또한 저항뿐만 아니라 인덕터나 커패시터로 종단된 다중 전송션을 해석하기 위해 상태변수 표현식 (state-variable formulation)을 이용하였다, TEM(Transverse Electromagnetic) 셀을 이용해서 다중 전송선에서의 누화와 외부 입사장에 의한 전자파 결합현상을 시간영역에서 측정하였고 이론적으로 구한 시율레이션 결과 와 비교하여 잘 일치함을 확인하였다. 또한 PCB와 같이 KSC 3340 TIV보다 상대적으로 손실이 큰 전송선 구조 인 경우 도체의 길이가 짧아도 손실을 포함해야 정확한 예측이 가능함을 확인하였고 저주파에서의 저항은 정상 시간 응답을 결정하고 고주파에서의 임피던스는 초기시간 응답을 결정함을 보였다.

• IMMUNE NETWORK
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• 제14권6호
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• pp.296-306
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• 2014

There is growing evidence that crosstalk between mantle cell lymphoma (MCL) cells and stromal microenvironments, such as bone marrow and secondary lymphoid tissues, promotes tumor progression by enhancing survival and growth as well as drug resistance of MCL cells. Recent advances in the understanding of lymphoma microenvironment have led to the identification of crucial factors involved in the crosstalk and subsequent generation of their targeted agents. In the present study, we evaluated the combinatory effect of blocking antibodies (Ab) targeting CXCR4 and VLA-4, both of which were known to play significant roles in the induction of environment-mediated drug resistance (EMDR) in MCL cell line, Jeko-1. Simultaneous treatment with anti-CXCR4 and anti-VLA-4 Ab not only reduced the migration of Jeko-1 cells into the protective stromal cells, but also enhanced sensitivity of Jeko-1 to a chemotherapeutic agent to a greater degree than with either Ab alone. These combinatorial effects were associated with decreased phosphorylation of ERK1/2, AKT and NF-${\kappa}B$. Importantly, drug resistance could not be overcome once the adhesion of Jeko-1 to the stromal occurred despite the combined use of Abs, suggesting that the efforts to mitigate migration of MCLs should be attempted as much as possible. Our results provide a basis for a future development of therapeutic strategies targeting both CXCR4 and VLA-4, such as Ab combinations or bispecific antibodies, to improve treatment outcomes of MCL with grave prognosis.

• 한국전기전자재료학회:학술대회논문집
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• 한국전기전자재료학회 2002년도 춘계학술대회 논문집 디스플레이 광소자 분야
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• pp.105-108
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• 2002

We report on the polarization-insensitive design and fabrication of an arrayed waveguide gratings (AWG's) using sol-gel derived silica glass films formed on fused silica substrates to provide cheap and stable tools for better design. An arrayed-waveguide grating multiplexer with raised structure is fabricated in order to effect polarization sensitivity. Since polarization is usually not known after propagation in an optical fiber. passive WDM components such as monolithic wavelength demultiplexer have to be polarization insensitive. Here, we observed that polarization have effect on crosstalk of output spectrum in arrayed-waveguide grating

• 한국전기전자재료학회:학술대회논문집
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• 한국전기전자재료학회 2007년도 하계학술대회 논문집 Vol.8
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• pp.53-54
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• 2007

Charged particle type display using particles which have opposite charge and color is based on effect of reversible optical property due to electric field. we designed mask pattern for fabrication of the charged particle type display based on glass substrate and investigated cell gap dependent of driving voltage and selectively driving method. the panel driven by our selectively driving method, we could obtain image which had vary little crosstalk caused by electrical interference and conform the last image maintained by memory effect without additional voltage.

• 한국통신학회논문지
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• 제37권4A호
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• pp.219-226
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• 2012

본 연구는 조명 및 무선통신이 동시에 가능한 가시광 송수신기에 대해 가시광 통신 본연의 가시성, 무선 통신의 사용 편의성 그리고 고속의 통신 속도를 고려해 edge-emitting laser diode와 silicon photo diode를 기반으로한 고속 가시광 무선 송수신기를 구현하였다. 제안된 가시광 무선 송수신기는 120Mbit/s의 고속에서 양방향 전송이 가능하도록 설계되었으며 이때 발생하는 누화(crosstalk)를 방지하기 위한 방법으로 shielding 방식을 적용해 가시광 송수신기의 성능을 실험적으로 측정 분석하였다. 또 수신기의 시야각 확대를 위한 방법으로는 새로운 구조의 광학적 antenna를 적용해 광학적 antenna가 없는 두 개의 송수신기 사이의 전송링크 특성과 광학적 antenna를 사용한 두 개의 송수신기 사이의 전송링크 특성을 2차원 평면상에서 전송거리, 적용범위 그리고 기울임 정도를 변화시켜 실험과 시뮬레이션을 통해 그 성능을 비교 분석하였다.