• Korean Journal of Applied Biomechanics
• /
• v.19 no.1
• /
• pp.179-186
• /
• 2009

This works studied to compare gas analyzer with accelerometer and the estimation of energy expenditure based on different attaching position of tri-axial accelerometer such as waist and top of the foot Based on the fact that oxygen intake increases more radically linearly during walking more than 8.0km/hr. 9 male subjects performed walking and running on the treadmill with speed of $1.5{\sim}8.5km$/hr and $4.5{\sim}13.0km$/hr, respectively. Commercially available Nike + iPod Sports kit was used to compare energy expenditure with sensor module attached to their foot. Actual energy expenditure was determined by a continuous direct gas analyzer and two multiple regression equations of walking and running mode for different attaching position were developed. Results showed that estimation accuracy of energy expenditure using waist mounted accelerometer was higher than that of the top of the foot and Nike + iPod Sports kit. Results of energy expenditure based on waist and top of the foot showed that the crossover state of energy expenditure occurred at 7.5km/hr. But Nike + iPod Sports kit could not find intersection of energy expenditure in all nine subjects. Therefore the sensor module attached to the waist and separate multi regression equation by walking and running mode was the best to estimate more accurate prediction.

• The Journal of Internal Korean Medicine
• /
• v.43 no.4
• /
• pp.582-595
• /
• 2022

Objectives: To investigate the effects of acupuncture at GV20 and EX-HN1 on cerebral blood flow (CBF) velocity and cerebrovascular reactivity (CVR) in the middle cerebral arteries (MCA) and anterior cerebral arteries (ACA) and to compare the effects to acupuncture at GV20. Methods: The study was a randomized, crossover trial that included 10 healthy men aged 20 to 29 years who underwent acupuncture treatment four times with a washout period of one week. The CBF velocity and CVR were measured by transcranial Doppler sonography (TCD) on both MCAs at the first and second visits, and both ACAs at the third and fourth visits. Participants were randomly assigned to one of two groups (A and B) before the first and third visits. Group A received two phases of acupuncture intervention at a single GV20 point and a combination of GV20 and EX-HN1 acupoints. Group B received the same interventions, but in the reverse order. Results: The increase in CO₂ reactivity was significantly higher for the combination acupoints of GV20 and EX-HN1 than for the GV20 single acupoint in both MCAs (Right: 136 to 178, p=0.017; Left: 127 to 191, p=0.017) and ACAs (Right: 133 to 158, p=0.013; Left: 122 to 168, p=0.025). No significant change was noted in the corrected velocity at PETCO₂ 40 mmHg, blood pressure, or heart rate. Conclusions: The findings suggest that improvement of the CBF in the MCA and ACA after GV20 acupuncture increases when acupuncture is also performed at EX-HN1. These results clinically support the combined use of EX-HN1 and GV20 to treat disorders of MCA and ACA circulation.

• Journal of Intelligence and Information Systems
• /
• v.19 no.4
• /
• pp.55-79
• /
• 2013

In this paper, we propose a hybrid genetic algorithm (HGA) approach to effectively solve the reverse logistics network with centralized centers (RLNCC). For the proposed HGA approach, genetic algorithm (GA) is used as a main algorithm. For implementing GA, a new bit-string representation scheme using 0 and 1 values is suggested, which can easily make initial population of GA. As genetic operators, the elitist strategy in enlarged sampling space developed by Gen and Chang (1997), a new two-point crossover operator, and a new random mutation operator are used for selection, crossover and mutation, respectively. For hybrid concept of GA, an iterative hill climbing method (IHCM) developed by Michalewicz (1994) is inserted into HGA search loop. The IHCM is one of local search techniques and precisely explores the space converged by GA search. The RLNCC is composed of collection centers, remanufacturing centers, redistribution centers, and secondary markets in reverse logistics networks. Of the centers and secondary markets, only one collection center, remanufacturing center, redistribution center, and secondary market should be opened in reverse logistics networks. Some assumptions are considered for effectively implementing the RLNCC The RLNCC is represented by a mixed integer programming (MIP) model using indexes, parameters and decision variables. The objective function of the MIP model is to minimize the total cost which is consisted of transportation cost, fixed cost, and handling cost. The transportation cost is obtained by transporting the returned products between each centers and secondary markets. The fixed cost is calculated by opening or closing decision at each center and secondary markets. That is, if there are three collection centers (the opening costs of collection center 1 2, and 3 are 10.5, 12.1, 8.9, respectively), and the collection center 1 is opened and the remainders are all closed, then the fixed cost is 10.5. The handling cost means the cost of treating the products returned from customers at each center and secondary markets which are opened at each RLNCC stage. The RLNCC is solved by the proposed HGA approach. In numerical experiment, the proposed HGA and a conventional competing approach is compared with each other using various measures of performance. For the conventional competing approach, the GA approach by Yun (2013) is used. The GA approach has not any local search technique such as the IHCM proposed the HGA approach. As measures of performance, CPU time, optimal solution, and optimal setting are used. Two types of the RLNCC with different numbers of customers, collection centers, remanufacturing centers, redistribution centers and secondary markets are presented for comparing the performances of the HGA and GA approaches. The MIP models using the two types of the RLNCC are programmed by Visual Basic Version 6.0, and the computer implementing environment is the IBM compatible PC with 3.06Ghz CPU speed and 1GB RAM on Windows XP. The parameters used in the HGA and GA approaches are that the total number of generations is 10,000, population size 20, crossover rate 0.5, mutation rate 0.1, and the search range for the IHCM is 2.0. Total 20 iterations are made for eliminating the randomness of the searches of the HGA and GA approaches. With performance comparisons, network representations by opening/closing decision, and convergence processes using two types of the RLNCCs, the experimental result shows that the HGA has significantly better performance in terms of the optimal solution than the GA, though the GA is slightly quicker than the HGA in terms of the CPU time. Finally, it has been proved that the proposed HGA approach is more efficient than conventional GA approach in two types of the RLNCC since the former has a GA search process as well as a local search process for additional search scheme, while the latter has a GA search process alone. For a future study, much more large-sized RLNCCs will be tested for robustness of our approach.

• Journal of Korean Biological Nursing Science
• /
• v.13 no.1
• /
• pp.8-15
• /
• 2011

Purpose: The purpose of this study was to analyze effects of hand drying methods after hand-washing. Hand drying methods consisted of spontaneous evaporation, paper towel, hand dryer with rubbing, and hand dryer without rubbing. Methods: The research design was a crossover design. The subjects were eighteen university students and randomly assigned in four group. Each group had the schedule of treatment. The schedule tested one drying method per a day and proceeded for 4 days. The data collection was performed from July 27 to July 30, 2010. Data were analyzed by Kruskal-Wallis, Mann-Whitney and Wilcoxon test. Results: There was significant difference between the after CFU between natural dry, paper towel, air dryer with hand rubbing, and air dryer without hand rubbing(p=.006). The after CFUs of paper towel, natural dry and air dryer without hand rubbing groups were statistically less than air dryer with hand rubbing group. Conclusion: It was shown that the paper towel, spontaneous evaporation and without rubbing hand dryer are effective hand drying interventions on reducing CFU on hand. However additional researches with large sample and strict methodology are needed.

• 한국신재생에너지학회:학술대회논문집
• /
• 2010.06a
• /
• pp.129.2-129.2
• /
• 2010

AEM which were used for solid alkaline fuel cell(SAFC) were prepared by photo polymerization in method pore-filling with various quaternary ammonium cationic monomers and crosslinkers without an amination process. Their specific thermal and chemical properties were characterized through various analyses and the physico-chemical properties of the prepared electrolyte membranes such as swelling behavior, ion exchange capacity and ionic conductivity were also investigated in correlation with the electrolyte composition. The polymer electrolyte membranes prepared in this study have a very wide hydroxyl ion conductivity range of 0.01 - 0.45S/cm depending on the composition ratio of the electrolyte monomer and crosslinking agent used for polymerization. However, the hydroxyl ion conductivity of the membranes was relatively higher at the whole cases than those of commercial products such as A201 membrane of Tokuyama. These pore-filling membranes have also excellent properties such as smaller dimensional affects when swollen in solvents, higher mechanical strength, lowest electrolyte crossover through the membranes, and easier preparation process compared of traditional cast membranes. The prepared membranes were then applied to solid alkaline fuel cell and it was found comparable fuel cell performance to A201 membrane of Tokuyama.

• Journal of Korean society of Dental Hygiene
• /
• v.8 no.2
• /
• pp.67-76
• /
• 2008

The purpose of this study was to determine the effect of dentifrice containing 0.1% extracts of garlic on dental plaque and gingivitis in a double blind and crossover clinical studies in 33 healthy adults aged from 20 to 22 years who provided a consent for their participation. Oral examination was performed through clinical periods and on day of baseline, 6, 13, 19, 25 days plaque index and gingival index were scored by Turesky' modified index and L$\ddot{o}$e & Silness index. After 12, 19, 25 days use of their respective dentifrices, statistically decreases of plaque index, gingival index were shown in both the experimental and the control group, respectively, Experimental group exhibited significantly the lower plaque levels and the higher levels of gingival health by the use of the dentifrices contained extract of garlic from 12 days compare with control group(p<0.05). The degree of decrease was more significant on gingivitis level of the experimental group than the control group(p <0.05). This result indicate that the use of dentifrice containing extract of garlic has a positve effect in preventing plaque and gingivitis and treating periodontal diseases.

• Biomolecules & Therapeutics
• /
• v.11 no.2
• /
• pp.145-150
• /
• 2003

The bioequivalence of two tablet formulations of 12.72mg domperidone maleate (Sinil "$Perinal^{\circledR}$" tablets vs. Janssen Korea "Motilium-$M^{\circledR}$" tablets) was assessed in healthy Korean volunteers after oral administration in a randomized crossover study. Blood samples were collected at spccified time intervals, and plasma concentration was measured as the amount of domperidone base using a validated HPLC method. The pharmacokinetic parameters of $AUC_{0{\rightarrow}48},\; C_{max},\;T_{max}$ and $t_{1/2}$ were determined from plasma concentration-time profile of two formulations. Any significant statistical differences were not observed between these two formulations. On the evaluation of bioequivalence according to Korea Food and Drug Administration Guideline, 90％ confidence limits after logmithmic transformation fell within the acceptable range (log 0.8∼log 1.25). Based on these data, it can be concluded that two domperidone maleate tablets showed comparable pharmacokinetic profiles, which means that the Sinil "$Perinal^{\circledR}$" tablet is bioequivalent to the Janssen Korea ""Motilium-M$^{\circledR}$".

• Korean Journal of Materials Research
• /
• v.28 no.6
• /
• pp.330-336
• /
• 2018

In this study, a membrane electrode assembly(MEA) composed of three electrodes(anode, cathode, and reference electrode) is designed to investigate the effects of methanol concentration on the overpotentials of anode and cathode in direct methanol fuel cells(DMFCs). Using the three-electrode cell, in-situ analyses of the overpotentials are carried out during direct methanol fuel cell operation. It is demonstrated that the three-electrode cell can work effectively in transient state operating condition as well as in steady-state condition, and the anode and cathode exhibit different overpotential curves depending on the concentration of methanol used as fuel. Therefore, from the real-time separation of the anode and cathode overpotentials, it is possible to more clearly prove the methanol crossover effect, and it is expected that in-situ analysis using the three-electrode cell will provide an opportunity to obtain more diverse results in the area of fuel cell research.

• Proceedings of the Korean Operations and Management Science Society Conference
• /
• 2001.10a
• /
• pp.253-256
• /
• 2001

Today's rapid development in the computer and network technology makes the environment which enables the companies to consider their decisions on the wide point of view and enables the software vendors to make the software packages to help these decisions. To make these software packages, many algorithms should be developed. The production and distribution planning problem belongs to those problems that industry manufacturers daily face in organizing their overall production plan. However, this combinatorial optimization problem can not be solved optimally in a reasonable time when large instances are considered. This legitimates the search for heuristic techniques. As one of these heuristic techniques, genetic algorithm has been considered in many researches. A standard genetic algorithm is a problem solving method that apply the rules of reproduction, gene crossover, and mutation to these pseudo-organisms so those organisms can Pass beneficial and survival-enhancing traits to new generation. This standard genetic algorithm should not be applied to this problem directly because when we represent the chromosome of this problem, there may exist high epitasis between genes. So in this paper, we proposed the hybrid genetic algorithm which turns out to better result than standard genetic algorithms

• Journal of Electrical Engineering and Technology
• /
• v.8 no.5
• /
• pp.1012-1020
• /
• 2013

In this work, Self-adaptive Differential Evolutionary (SaDE) algorithm is proposed to solve Optimal Location and Size of Capacitor (OLSC) problem in radial distribution networks. To obtain the SaDE algorithm, two improvements have been applied on control parameters of mutation and crossover operators. To expand the study, three load conditions have been considered, i.e., constant, varying and effective loads. Objective function is introduced for the load conditions. The annual cost is fitness of problem, in addition to this cost, CPU time, voltage profile, active power loss and total installed capacitor banks and their related costs have been used for comparisons. To confirm the ability of each improvements of SaDE, the improvements are studied both in separate and simultaneous conditions. To verify the effectiveness of the proposed algorithm, it is tested on IEEE 10-bus and 34-bus radial distribution networks and compared with other approaches.