• Tuberculosis and Respiratory Diseases
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• v.68 no.4
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• pp.218-225
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• 2010

Background: Bronchoalveolar lavage (BAL) is a useful technique to recover lower airway fluid and cells involved in many respiratory diseases. Miliary tuberculosis is potentially lethal, but the clinical manifestations are nonspecific and typical radiologic findings may not be seen until late in the course of disease. In addition, invasive procedures are often needed to confirm disease diagnosis. This study analyzed the cells and the T-lymphocyte subset in BAL fluid from patients with miliary tuberculosis to determine specific characteristics of BAL fluid that may help in the diagnosis of miliary tuberculosis, using a less invasive procedure. Methods: On a retrospective basis, we enrolled 20 miliary tuberculosis patients; 12 patients were male and the mean patient age was $40.5{\pm}16.2$ years. We analyzed differential cell counts of BAL fluid and the T-lymphocyte subset of BAL fluid. Results: Total cells and lymphocytes were increased in number in the BAL fluid. The percentage of CD4+ Tlymphocytes and the CD4/CD8 ratio in BAL fluid were significantly decreased and the percentage of CD8+ T-lymphocytes was relatively higher. These findings were more prominent in patients infected with the human immunodeficiency virus (HIV). In the HIV-infected patients, the proportion of lymphocytes was significantly higher in BAL fluid than in peripheral blood. There were no significant differences between the BAL fluid and the peripheral blood T-lymphocytes subpopulation. Conclusion: BAL fluid in patients with miliary tuberculosis demonstrated lymphocytosis, a lower percentage of CD4+ T-lymphocytes, a higher percentage of CD8+ T-lymphocytes, and a decreased CD4/CD8 ratio. These findings were more significant in HIV-infected subjects.

• Tuberculosis and Respiratory Diseases
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• v.52 no.4
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• pp.376-384
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• 2002

Background : The mortality from acute respiratory distress syndrome(ARDS) in the late stage, which is characterized by progressive pulmonary fibroproliferation, is ${\geq}80%$. Although previous prospective trials failed to show a survival benefit of steroid therapy in early ARDS, recently, a few of reports have described the survival benefit of the long-term use of steroid in patients with late ARDS. In this study, we analyzed the effect of steroid therapy on patients with late ARDS retrospectively in a single. Medral intensive care unit (MICU). Methods : Over a 3-year period, the medical records of 48 ARDS patients who had been on mechanical ventilation more than 8 days were reviewed. 14 patients were treated by the long-term use of methylprednisolone and another 34 patients served as a control. Both groups were comparable regarding clinical and physiologic data lung injury score(LIS), multiple organ failure score, APACHE III and SAPS II score. Because steroid was instituted after 8 days of advanced mechanical ventilatory support in average, we arbitrarily defined the $8^{th}$ day of ARDS as first day of the study. Results : Initially, the groups had similar PF($PaO_2/FiO_2$) ratio, LIS, APACHE III and SAPS II score. By 7th day after the start of steroid therapy, there were significant improvements in PF ratio, LIS, APACHE III and SAPS II score. The mortality in the steroid treated group was significantly lower(42.9% vs 73.5%, p<0.05). Conclusion : Although the data of this study was retrospective and was not randomized, in order to improve the patient's outcomes, steroid therapy should be considered in late ARDS patients. However, prospective trials are needed to define the indication and the effect of steroid therapy in late ARDS.

• Proceedings of the KSME Conference
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• 2001.06e
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• pp.329-334
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• 2001

In order to investigate the operating characteristics of a supersonic steam ejector, the axisymmetric, compressible, Reynolds-averaged, Navier-Stokes computations are performed using a finite volume method. The secondary and back pressures of the ejector system with a second throat are changed to investigate their effects on the suction mass flow. Three operation modes of the steam ejector system, the critical mode, subcritical mode and back flow mode, are discussed to predict the critical suction mass flow. The present computations are validated with some experimental results. The secondary and back pressures of the supersonic steam ejector significantly affect the critical suction mass flow. The present computations predict the experimented critical mass flow with fairly good accuracy. A good correlation is obtained for the critical suction mass flow. The present results show that provided the primary nozzle configuration and secondary pressure are known, we can predict the critical mass flow with good accuracy.

• Journal of Korean Society of Steel Construction
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• v.17 no.6 s.79
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• pp.699-705
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• 2005

This paper investigates critical loads of tapered cantilever columns with a tip mass, subjected to a follower force. The linearly tapered solid rectangular cross-sections are adopted as the column taper. The differential equation governing free vibrations of such columns, also called Beck's columns, is derived using the Bernoulli-Euler beam theory. Both divergence and flutter critical loads are calculated from the load-frequency curves that are obtained by solving the differential equation. The critical loads are presented as functions of various non-dimensional system parameters, namely, the taper type, the subtangential parameter, and the mass ratio.

• Proceedings of the Korean Geotechical Society Conference
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• 2008.03a
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• pp.211-219
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• 2008

The hazard warning levels are necessary for the rational design and safety construction of underground space, as mountain and urban tunnel. Sakurai provided the hazard warning levels for assessing the stability of tunnels using the critical strain of rock mass, which is defined as a ratio between uni-axial compressive strength and the Young's modulus. The concept of critical strain guidelines is introduced in this study for the assessment of tunnel safety during excavation. Moreover, in this paper, the critical strain properties of sedimentary rock in Korea has investigated and analysed in detail by Lab. test, as the uniaxial compression tests. Finally, critical strain properties of sedimentary rock is discussed the relationship of failure strain values, uniaxial compression strengths and Young's modulus.

• Proceedings of the Korean Geotechical Society Conference
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• 2008.03a
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• pp.821-832
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• 2008

The hazard warning levels are necessary for the rational design and safety construction of underground space, as mountain and urban tunnel. Sakurai provided the hazard warning levels for assessing the stability of tunnels using the critical strain of rock mass, which is defined as a ratio between uni-axial compressive strength and the Young's modulus. The concept of critical strain guidelines is introduced in this study for the assessment of tunnel safety during excavation. Moreover, in this paper, the critical strain properties of sedimentary rock in Korea has investigated and analysed in detail by Lab. test, as the uniaxial and triaxial compression tests. Finally, critical strain properties of sedimentary rock on uniaxial and triaxial stress condition is discussed the relationship of failure strain values, uniaxial and triaxial compression strengths, confining pressure and Young's modulus.

• KIEE International Transactions on Power Engineering
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• v.2A no.4
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• pp.131-135
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• 2002

This paper describes a new ultra-fast contingency screening algorithm for on-line TSA without time simulation. All machines are represented in a classical model and the stability index is defined as the ratio between acceleration power during a fault and deceleration power after clearing the fault. Critical clustering of machines is done based on the stability index, and the power-angle curve of the critical machines is drawn assuming that the angles of the critical machines increase uniformly, while those of the non-critical ones remain constant. Finally, the critical clearing time (CCT) is computed using the power-angle curve. The proposed algorithm is tested on the KEPCO system comprised of 900-bus and 230-machines. The CCT values computed with the screening algorithm are in good agreement with those computed using the detailed model and the SIME method. The computation time for screening about 270 contingencies is 17 seconds with 1.2 GHz PC.

• Structural Engineering and Mechanics
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• v.55 no.3
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• pp.605-638
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• 2015

It is intended to perform buckling analysis of steel gabled frames with tapered members and flexible connections. The method is based on the exact solutions of the governing differential equations for stability of a gabled frame with I-section elements. Corresponding buckling load and subsequently effective length factor are obtained for practical use. For several popular frames, the influences of the shape factor, taper ratio, span ratio, flexibility of connections and elastic rotational and translational restraints on the critical load, and corresponding equivalent effective length coefficient are studied. Some of the outcomes are compared against available solutions, demonstrating the accuracy, efficiency and capabilities of the presented approach.

• Geotechnical Engineering
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• v.14 no.3
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• pp.63-72
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• 1998

Laboratory model test results for ultimate uplift capacity of horizontal circular anchors embedded in soft clay overlain by dense sand are presented. The effect of the critical embedment ratio on the thickness of the clay layer was evalyated. An approximate preocedure for estimating the net ultimate capacity is presented.

• Journal of KSNVE
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• v.8 no.2
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• pp.353-360
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• 1998

In this paper, a modeling method for the bending vibration analysis of rotating Timoshenko beams with concentrated mass and mass moment of inertia is presented. The shear and rotary inertia effects become critical for the accurate estimation of the natural frequencies and mode shapes as the slenderness ratio decreases. The natural frequencies obtained by using the Timoshenko beam theory are lower than those by using the Euler beam theory. The critical angular speed, which does not exist only with the concentrated mass, exists with the concentrated mass moment of inertia.