• Journal of the Korean Data and Information Science Society
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• 제22권4호
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• pp.795-801
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• 2011

In machine learning and statistics it is often the case that some variables are not important, while some variables are more important than others. We propose a novel algorithm for selecting such relevant variables in the kernel Cox regression. We employ the weighted version of ANOVA decomposition kernels to choose optimal subset of relevant variables in the kernel Cox regression. Experimental results are then presented which indicate the performance of the proposed method.

• 응용통계연구
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• 제7권2호
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• pp.53-77
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• 1994

병원의 임상연구실험에서 종종 환자들의 치료에 따른 병세의 호전상태를 여러단계로 분류하여 상이한 치료방법에 따른 치료효과간의 차이를 알고자 하는 경우가 있다. 이와 같이 다중상태의 생존자료분석을 위한 한가지 방법으로 본 논문에서는 비동형의 Markov 모형에 Cox 회귀모형을 적용하여 회귀계수와 기저생존함수, 그리고 이를 바탕으로 반응확률함수를 추정하고 아울러 이들 추정량들의 대표본 성질들을 셈과정(Counting process) 기법을 이용하여 알아 보았다. 그리고 본 논문의 결과에 대해 실제 예를 들어 보였다.

• 응용통계연구
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• 제34권6호
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• pp.957-968
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• 2021

역중도절단확률가중(inverse censoring probability weighting, ICPW)은 생존분석에서 흔히 사용되는 방법이다. 중도절단 회귀모형과 같은 ICPW 방법의 응용에 있어서 중도절단 확률의 정확한 추정은 핵심적인 요소라고 할 수 있다. 본 논문에서는 중도절단 확률의 추정이 ICPW 기반 중도절단 회귀모형의 성능에 어떠한 영향을 주는지 모의실험을 통하여 알아보았다. 모의실험에서는 Kaplan-Meier 추정량, Cox 비례위험(proportional hazard) 모형 추정량, 그리고 국소 Kaplan-Meier 추정량 세 가지를 비교하였다. 국소 KM 추정량에 대해서는 차원의 저주를 피하기 위해 공변량의 차원축소 방법을 추가적으로 적용하였다. 차원축소 방법으로는 흔히 사용되는 주성분분석(principal component analysis, PCA)과 절단역회귀(sliced inverse regression)방법을 고려하였다. 그 결과 Cox 비례위험 추정량이 평균 및 중위수 중도절단 회귀모형 모두에서 중도절단 확률을 추정하는 데 가장 좋은 성능을 보여주었다.

• 한국수학사학회지
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• 제11권2호
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• pp.63-76
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• 1998

When teaching the linear regression analysis in the class, the power transformation must be introduced to fit the linear regression model for nonlinear data. Box and Cox (1964) proposed the attractive power transformation technique which is so called Box-Cox transformation. In this paper, an effective algorithm selecting an appropriate value for Box-Cox transformation is developed which is considered to find a value minimizing error sum of squares. When the proposed algorithm is used to find a value for transformation, the number of iterations needs to be considered. Thus, the number of iterations is examined through simulation study. Since SAS is one of most widely used packages and does not provide the procedure that performs iterative Box-Cox transformation, a SAS program automatically choosing the value for transformation is developed. Hence, the students could learn how the Box-Cox transformation works, moreover, researchers can use this for analysis of data.

• Journal of the Korean Data and Information Science Society
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• 제4권
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• pp.1-11
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• 1993

The Cox's regression model is frequently used for covariate effects in survival data analysis, But, much of the statistical work has focused on asymptotic behavior so the small sample evaluation has been neglected. In this paper, we compare the small or moderate sample performances of the survival function estimators for the Cox's regression model using bootstrap method. The smoothed PL type estimator and the Link estimator are slightly better than corresponding the PL type estimator and the Nelson type estimator in the sense of the achieved error rates.

• Communications for Statistical Applications and Methods
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• 제11권2호
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• pp.227-233
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• 2004

This paper presents our work on constructing a model that is intended to predict the probability of attrition at specified points in time among customers of an insurance company. There are some difficulties in building a data-based model because a data set may contain possibly censored observations. In an effort to avoid such kind of problem, we performed logistic regression over specified time intervals while using explanatory variables to construct the proposed model. Then, we developed a Cox-type regression model for estimating the probability of attrition over a specified period of time using time-dependent explanatory variables subject to changes in value over the course of the observations.

• Journal of the Korean Data and Information Science Society
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• 제12권1호
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• pp.103-125
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• 2001

The Box-Cox transformation is a well known family of power transformation that brings a set of data into agreement with the normality assumption of the residuals and hence the response variable of a postulated model in regression analysis. This paper proposes a new method for estimating the Box-Cox transformation using maximization of the Sample Entropy statistic which forces the data to get closer to normal as much as possible. A comparative study of the proposed procedure with the maximum likelihood procedure, the procedure via artificial regression estimation, and the recently introduced maximization of the Shapiro-Francia W' statistic procedure is given. In addition, we generate a table for the optimal spacings parameter in computing the Sample Entropy statistic.

• 대한간호학회지
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• 제49권5호
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• pp.575-585
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• 2019

Purpose: The purpose of this study was to develop predictive models for pressure ulcer incidence using electronic health record (EHR) data and to compare their predictive validity performance indicators with that of the Braden Scale used in the study hospital. Methods: A retrospective case-control study was conducted in a tertiary teaching hospital in Korea. Data of 202 pressure ulcer patients and 14,705 non-pressure ulcer patients admitted between January 2015 and May 2016 were extracted from the EHRs. Three predictive models for pressure ulcer incidence were developed using logistic regression, Cox proportional hazards regression, and decision tree modeling. The predictive validity performance indicators of the three models were compared with those of the Braden Scale. Results: The logistic regression model was most efficient with a high area under the receiver operating characteristics curve (AUC) estimate of 0.97, followed by the decision tree model (AUC 0.95), Cox proportional hazards regression model (AUC 0.95), and the Braden Scale (AUC 0.82). Decreased mobility was the most significant factor in the logistic regression and Cox proportional hazards models, and the endotracheal tube was the most important factor in the decision tree model. Conclusion: Predictive validity performance indicators of the Braden Scale were lower than those of the logistic regression, Cox proportional hazards regression, and decision tree models. The models developed in this study can be used to develop a clinical decision support system that automatically assesses risk for pressure ulcers to aid nurses.

• 응용통계연구
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• 제21권2호
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• pp.327-340
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• 2008

본 연구에서는 오차항이 AR(1)을 따르는 회귀모형에서 올바른 추론을 도출하고자 모형식별의 문제를 다루었다. 이를 위해 Box-Cox 변환된 회귀모형을 고려하여 (i) Box-Cox 변환모형과 AR(1) 오차에 대한 동시 검정, (ii) AR(1) 오차가 존재하는 모형에서의 Box-Cox 변환모형에 대한 검정 그리고 (iii) 모형이 Box-Cox 변환되어 있을 때 오차가 AR(1) 과정을 따르는지에 대한 LM 검정통계량을 유도하였다. 특히 LM 검정방법에서 여러개의 모수가 비선형관계를 형성하고있어 정보행렬의 추정은 계산상 매우 어렵다. 따라서 정보행렬의 원소에 대한 기대값을 구함에 있어 Taylor전개를 이용하여 정보행렬을 구하고 이에 기반을 둔 LM 검정통계량($LM_E$)를 제안하고 모의실험결과 $LM_E$가 기존의 헤시안행렬에 기반을 둔 LM 검정통계량($LM_H$)에 비하여 유의수준을 잘 유지하고 있는 것으로 나타났다.

• Communications for Statistical Applications and Methods
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• 제24권6호
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• pp.583-604
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• 2017

The most popular regression model for the analysis of time-to-event data is the Cox proportional hazards model. While the model specifies a parametric relationship between the hazard function and the predictor variables, there is no specification regarding the form of the baseline hazard function. A critical assumption of the Cox model, however, is the proportional hazards assumption: when the predictor variables do not vary over time, the hazard ratio comparing any two observations is constant with respect to time. Therefore, to perform credible estimation and inference, one must first assess whether the proportional hazards assumption is reasonable. As with other regression techniques, it is also essential to examine whether appropriate functional forms of the predictor variables have been used, and whether there are any outlying or influential observations. This article reviews diagnostic methods for assessing goodness-of-fit for the Cox proportional hazards model. We illustrate these methods with a case-study using available R functions, and provide complete R code for a simulated example as a supplement.