• 제목/요약/키워드: Cox proportional Hazard model

검색결과 271건 처리시간 0.024초

주요 위험요인별 허혈성심질환 사망위험도 분석 (The relative risk of major risk factors of ischemic heart disease)

  • 고민정;한준태
    • Journal of the Korean Data and Information Science Society
    • /
    • 제21권2호
    • /
    • pp.201-209
    • /
    • 2010
  • 최근 10년간 허혈성심질환 사망은 급격히 증가하였기에 이에 대한 효과적인 예방대책이 매우 중요한 실정이다. 이에 본 연구에서는 1996년 국민건강보험공단 건강검진 수검자 2,268,018명을 약 10년간 추적하여 허혈성심질환의 주요 위험요인별 상대위험도를 콕스비례위험모형을 통해 파악하고자 하였다. 그 결과 남자에서는 체질량지수, 혈압, 흡연, 여자에서는 고혈압, 주관적 건강감 및 감마-글루타밀전이효소가 허혈성심질환과 유의한 관련성이 있었다.

서울시 홍대상권 내 업종변화 필지의 공간적 특성 분석 - 상업 젠트리피케이션의 관점에서 - (Analysis of Spatial Characteristics of Business-Type-Changed Parcel in Hongik-University Commercial Area, Seoul - Focused on the View Point of Commercial Gentrification -)

  • 김동준;김기중;이승일
    • 국토계획
    • /
    • 제54권2호
    • /
    • pp.5-16
    • /
    • 2019
  • The purpose of this study is to analyze the spatial characteristics of business-type-changed parcel in the Hongik-University commercial area, from the view point of commercial gentrification. A commercial gentrification occurs through a business-type-change in a spatial basic unit (microscopic spatial unit such as parcel) of an area which has not been considered in relavent policies and research. So, this study analyzed the spatial characteristics of business-type-changed parcels using the Cox's proportional hazard regression model. The main results of this study are as follows. First, as new developments in the adjacent area occur, the business-type-change probability increases. Second, by the commercial area division, the business-type-change probability is different. Finally, the accessibility is better, the probability is higher. These results could suggest that a consideration of the spatial characteristics form microscopic viewpoint is necessary to understand the commercial gentrification. And these could be used as basic data for a gentrification diagnostic and management system, which can predict gentrification from the view point of business-type-change on the basis of a parcel.

First Job Waiting Times after College Graduation Based on the Graduates Occupational Mobility Survey in Korea

  • Lee, Sungim;Moon, Jeounghoon
    • 응용통계연구
    • /
    • 제25권6호
    • /
    • pp.959-975
    • /
    • 2012
  • Each year research institutions such as the Korea Employment Information Service(KEIS), a government institution established for the advancement of employment support services, and Job Korea, a popular Korean job website, announce first job waiting times after college graduation. This provides useful information understand and resolve youth unemployment problems. However, previous reports deal with the time as a completely observed one and are not appropriate. This paper proposes a new study on first job waiting times after college graduation set to 4 months prior to graduation. In Korea, most college students hunt for jobs before college graduation in addition, the full-fledged job markets also open before graduation. In this case the exact waiting time of college graduates can be right-censored. We apply a Cox proportional hazards model to evaluate the associations between first job waiting times and risk factors. A real example is based on the 2008 Graduates Occupational Mobility Survey(GOMS).

A Study on the Conditional Survival Function with Random Censored Data

  • Lee, Won-Kee;Song, Myung-Unn
    • Journal of the Korean Data and Information Science Society
    • /
    • 제15권2호
    • /
    • pp.405-411
    • /
    • 2004
  • In the analysis of cancer data, it is important to make inferences of survival function and to assess the effects of covariates. Cox's proportional hazard model(PHM) and Beran's nonparametric method are generally used to estimate the survival function with covariates. We adjusted the incomplete survival time using the Buckley and James's(1979) pseudo random variables, and then proposed the estimator for the conditional survival function. Also, we carried out the simulation studies to compare the performances of the proposed method.

  • PDF

A Covariate-adjusted Logrank Test for Paired Survival Data

  • Jeong, Gyu-Jin
    • Communications for Statistical Applications and Methods
    • /
    • 제9권2호
    • /
    • pp.533-542
    • /
    • 2002
  • In this paper, a covariate adjusted logrank test is considered for censored paired data under the Cox proportional hazard model. The proposed score test resembles the adjusted logrank test of Tsiatis, Rosner and Tritchler (1985), which is derived from the partial likelihood. The dependence structure for paired data is accommodated into the test statistic by using' sum of square type' variance estimators. Several weight functions are also considered, which produce a class of covariate adjusted weighted logrank tests. Asymptotic normality of the proposed test is established and simulation studies with moderate sample size show the proposed test works well, particularly when there are dependence structure between treatment and covariates.

Estimating the Mixture of Proportional Hazards Model with the Constant Baseline Hazards Function

  • Kim Jong-woon;Eo Seong-phil
    • 한국신뢰성학회:학술대회논문집
    • /
    • 한국신뢰성학회 2005년도 학술발표대회 논문집
    • /
    • pp.265-269
    • /
    • 2005
  • Cox's proportional hazards model (PHM) has been widely applied in the analysis of lifetime data, and it can be characterized by the baseline hazard function and covariates influencing systems' lifetime, where the covariates describe operating environments (e.g. temperature, pressure, humidity). In this article, we consider the constant baseline hazard function and a discrete random variable of a covariate. The estimation procedure is developed in a parametric framework when there are not only complete data but also incomplete one. The Expectation-Maximization (EM) algorithm is employed to handle the incomplete data problem. Simulation results are presented to illustrate the accuracy and some properties of the estimation results.

  • PDF

60, 81mm 박격포탄의 저장수명 요인 연구 (A study on the factors affecting shelf-life for 60, 81mm mortar ammunition)

  • 장수희;전희주;조인호;윤근식;강민정;박동수
    • 응용통계연구
    • /
    • 제31권5호
    • /
    • pp.611-620
    • /
    • 2018
  • ASRP(Ammunition Stockpile Reliability Program; 저장탄약신뢰성평가) 업무는 인적, 물적 문제로 인하여 모든 탄에 대해 주기적 검사 수행이 어려운 실정으로, 저장탄약 수명예측 연구는 효율적인 ASRP 업무 수행에 기여할 수 있다. 본 연구는 2003년 2016년에 수행한 60,81mm 박격포탄약에 대한 ASRP 결과를 기초로 저장수명 요인을 연구하였다. 기존의 수명예측 연구에서 저장기간을 주요 독립변인으로 분석한 연구방법과는 다르게, 탄약고형태, 기상요인 등 저장환경을 독립변인으로 Cox의 비례위험모형을 활용하여 분석하였다. 그 결과 60, 81mm 박격포탄의 저장수명에 영향을 미치는 요인은 탄약고형태, 최고온도 요인, 강수량 요인으로 분석되었다.

Black Hispanic and Black Non-Hispanic Breast Cancer Survival Data Analysis with Half-normal Model Application

  • Khan, Hafiz Mohammad Rafiqullah;Saxena, Anshul;Vera, Veronica;Abdool-Ghany, Faheema;Gabbidon, Kemesha;Perea, Nancy;Stewart, Tiffanie Shauna-Jeanne;Ramamoorthy, Venkataraghavan
    • Asian Pacific Journal of Cancer Prevention
    • /
    • 제15권21호
    • /
    • pp.9453-9458
    • /
    • 2014
  • Background: Breast cancer is the second leading cause of cancer death for women in the United States. Differences in survival of breast cancer have been noted among racial and ethnic groups, but the reasons for these disparities remain unclear. This study presents the characteristics and the survival curve of two racial and ethnic groups and evaluates the effects of race on survival times by measuring the lifetime data-based half-normal model. Materials and Methods: The distributions among racial and ethnic groups are compared using female breast cancer patients from nine states in the country all taken from the National Cancer Institute's Surveillance, Epidemiology, and End Results cancer registry. The main end points observed are: age at diagnosis, survival time in months, and marital status. The right skewed half-normal statistical probability model is used to show the differences in the survival times between black Hispanic (BH) and black non-Hispanic (BNH) female breast cancer patients. The Kaplan-Meier and Cox proportional hazard ratio are used to estimate and compare the relative risk of death in two minority groups, BH and BNH. Results: A probability random sample method was used to select representative samples from BNH and BH female breast cancer patients, who were diagnosed during the years of 1973-2009 in the United States. The sample contained 1,000 BNH and 298 BH female breast cancer patients. The median age at diagnosis was 57.75 years among BNH and 54.11 years among BH. The results of the half-normal model showed that the survival times formed positive skewed models with higher variability in BNH compared with BH. The Kaplan-Meir estimate was used to plot the survival curves for cancer patients; this test was positively skewed. The Kaplan-Meier and Cox proportional hazard ratio for survival analysis showed that BNH had a significantly longer survival time as compared to BH which is consistent with the results of the half-normal model. Conclusions: The findings with the proposed model strategy will assist in the healthcare field to measure future outcomes for BH and BNH, given their past history and conditions. These findings may provide an enhanced and improved outlook for the diagnosis and treatment of breast cancer patients in the United States.

중소기업 청년인턴 취업자의 재직기간 분석 (Study on the determinants of employment duration in the youth-intern project)

  • 박성익;류장수;김종한;조장식
    • Journal of the Korean Data and Information Science Society
    • /
    • 제27권2호
    • /
    • pp.285-294
    • /
    • 2016
  • 취업자들이 재직기간이 경과하면서 이직 또는 실업 상태로 탈출확률 및 탈출요인 문제를 분석하는 것은 취업의 질을 측정할 수 있는 하나의 방법이다. 일반적으로 취업자들의 이직 또는 실업으로의 탈출확률은 취업자의 개인특성뿐만 아니라, 직종 특성에도 영향을 받는 복수의 분석단위를 가지게 된다. 복수의 분석단위를 가지는 위계적 (hierarchical) 자료구조에서는 직종별로 공유되는 특성이 존재하게 되어, 동일 직종 집단 내의 상관이 발생할 수 있다. 따라서 본 연구에서는 취업자 개인특성 (1-수준)과 직종 특성 (2-수준)의 위계적 자료구조 하에서 콕스의 비례위험 모형 (Cox's proportional hazard model)을 이용하여 중소기업 청년인턴사업에 참여한 취업자들의 재직기간 중 실직 및 이직으로의 탈출요인을 분석하였다. 분석결과를 요약하면 다음과 같다. 처리집단 (인턴집단)이 통제집단 (비인턴집단)에 비해서 탈출확률이 통계적으로 유의하게 낮음을 알 수 있다. 또한 남자들이 여자들에 비해서 탈출할 확률이 높고, 연령이 높을수록 탈출할 확률이 더 낮아지는 것을 알 수 있다. 그리고 기업규모가 클수록 탈출확률이 낮으며, 직종별로는 관리사무 관련직에 비해서 전문 서비스 관련직의 탈출확률이 더 낮게 나타났다.

Kernel Estimation of Hazard Ratio Based on Censored Data

  • 최명희;이인석;송재기
    • Journal of the Korean Data and Information Science Society
    • /
    • 제12권2호
    • /
    • pp.125-143
    • /
    • 2001
  • We, in this paper, propose a kernel estimator of hazard ratio with censored survival data. The uniform consistency and asymptotic normality of the proposed estimator are proved by using counting process approach. In order to assess the performance of the proposed estimator, we compare the kernel estimator with Cox estimator and the generalized rank estimators of hazard ratio in terms of MSE by Monte Carlo simulation. Two examples are illustrated for our results.

  • PDF