• Smart Structures and Systems
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• 제14권6호
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• pp.1031-1054
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• 2014

Real-time hybrid simulation (RTHS) of a stacked wood shear wall retrofitted with a rate-dependent seismic energy dissipation device (viscous damper) was conducted at the newly constructed Structural Engineering Laboratory at the University of Alabama. This paper describes the implementation process of the RTHS focusing on the controller scheme development. An incremental approach was adopted starting from a controller for the conventional slow pseudodynamic hybrid simulation and evolving to the one applicable for RTHS. Both benchmark-scale and full-scale tests are discussed to provide a roadmap for future RTHS implementation at different laboratories and/or on different structural systems. The developed RTHS controller was applied to study the effect of a rate-dependent energy dissipation device on the seismic performance of a multi-story wood shear wall system. The test specimen, setup, program and results are presented with emphasis given to inter-story drift response. At 100% DBE the RTHS showed that the multi-story shear wall with the damper had 32% less inter-story drift and was noticeably less damaged than its un-damped specimen counterpart.

• 한국산업정보학회:학술대회논문집
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• 한국산업정보학회 2000년도 춘계학술대회논문집
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• pp.59-64
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• 2000

능동 레이더 반사기는 지금까지는 특히 비행물체와 미사일의 레이더 유효 반사 면적을 효과적으로 증가시키기 위한 군사적 응용에만 사용이 제한되어져 왔기 때문에 그다지 친숙한 용어는 아니다. 레이더 트랜스폰더의 가장 잘 알려진 응용은 군용의 피아 식별 장치 (IFF ; Identification Friend or Foe)와 이것의 민간 항공부문이고, 항공 교통 관제(An , hir Traffic Control)를 위한 2차 감시 레이더(SSR : Second Surveillance Radar), 그리고 보다 최근에는 전 세계 해상 조난 및 안전 제도(GMDSS ; Global Maritime Distress and Safety System)의 수색 구조용 트랜스폰더(SART ; Search And Rescue Transponder)등이 있다. 최근 연안이나 대양에서의 해난사고가 빈번히 발생되고 있으므로, 이로 인한 해양오염이 심각한 실정이다. 이제는 전통적인 항해표지 및 시설로써 해상교통의 안전을 유지하기에는 충분치 못하며, 새로운 개념과 구조가 적용되어야만 한다. 따라서 본 연구에서는 개선된 구조를 가진 능동 레이더 반사기를 제안하고 제작하였다. 제작된 시스템은 기존의 시설에 비해 높은 성능 향상을 보인다.

• 한국통신학회논문지
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• 제23권5호
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• pp.1349-1359
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• 1998

본 논문에서는 디지털 FM 스테레오 합성 신호 발생기(FM stereo composite signal generator)의 구현 결과를 제시하였다. 직접 디지털 주파수 합성기(DDFS)를 응용하여 단일 칩으로 디지털화 하였으며, $1.0\mu\textrm{m}$ CMOS 게이트­어레이 기술로 구현하였다. 설계 결과는 시뮬레이션을 통해 신호 발생 과정을 검증하였고, 디지털 칩을 실장한 평가용 인쇄회로기판을 제작하여 신호 발생 값을 비교 분석하였다. 측정 결과 디지털-아날로그 변환기의 비트 수가 12비트일 때 신호 대 잡음비가 74dB가 측정되었으며, 이는 아날로그 회로보다 14dB 더 우수한 것이다. 범용 스테레오 입출력으로 16비트 디지털-아날로그 변환기를 사용할 경우 아날로그 방식보다 훨씬 우수한 스펙트럼 순수도를 얻을 수 있을 것으로 기대한다. 디지털 FM 스테레오 합성 신호 발생기는 신호 대 잡음비, 정확도, 튜닝 안정성,그리고 집적도측면에서 기존의 아날로그회로보다 우수한 특성을 보인다.

• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• 제35권5호
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• pp.304-309
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• 2009

Purpose: Fibrous dysplasia (FD) is a fibro-osseous disease associated with activating missense mutations of the gene encoding the $\alpha$-subunit of stimulatory G protein. FD may affect a single bone (called monostotic form) or multiple bones (called polyostotic form). The extent of lesions reflects the onset time of mutation. In this study, cells from monostotic FD in maxilla of a patient were isolated and cultured in vitro for characterization. Materials and Methods: The single cells were released from FD lesion which was surgical specimen from 15 years-old boy. These isolated cells were cultured in vitro and tested their proliferation activity with MTT assay. In osteogenic media, these cells underwent differentiation process comparing with its normal counterpart i.e. bone marrow stromal cells. The proliferated FD cells were detached and transplanted into the dordsal pocket of nude mouse and harvested in 6 weeks and 12 weeks. Results and Summary: FD cells have an increased proliferation rate and poor differentiation. As a result, cells isolated from FD lesion decreased differentiation into osteoblast and increased proliferation capacity. MTT assay presented that proliferation rate of FD cells were higher than control. However, the mineral induction capacity of FD was lesser than that of control. Monostotic FD cells make fewer amounts of bone ossicles and most of them are woven bone rather than lamellar bone in vivo transplantation. In transplanted FD cells, hematopoietic marrow were not seen in the marrow space and filled with the organized fibrous tissue. Therefore, they were recapitulated to the original histological features of FD lesion. Collectively, these results indicated that the FD cells were shown that the increased proliferation and decreased differentiation potential. These in vitro and in vivo system can be useful to test FD cell's fate and possible.

• 한국정보통신학회:학술대회논문집
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• 한국정보통신학회 2015년도 춘계학술대회
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• pp.947-950
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• 2015

우리나라 전체 교통사고 원인에 있어서 졸음운전은 음주운전보다도 더 큰 비중을 차지하고 있는 위험요소로 나타나고 있다. 따라서 사전에 졸음운전사고를 예방하기 위하여 운전자의 졸음을 인식하고 경고해주는 시스템 개발과 관련된 연구가 활발하게 이루어지고 있는 추세이며, 졸음의 지표는 뇌파의 알파파를 분석하는 것이 효과적이라는 선행 연구결과들이 발표되었다. 본 연구에서는 LabView 프로그램을 이용하여 졸음지표를 검출할 수 있는 신호처리 알고리즘을 적용시킨 뇌파측정 장치를 자체 개발하였다. 소수의 실험자를 대상으로 졸음유도 실험을 실시한 결과 알파파의 상대 파워스펙트럼 변화를 기준으로 졸음상태를 의미하는 뇌파의 패턴을 검출 할 수 있었다. 이후 기존의 뇌파측정 장비들을 사용하여 측정한 졸음패턴과 비교분석한 결과 유사한 패턴을 나타내는 것을 확인 할 수 있었다. 이러한 결과를 바탕으로 차후 운전자의 졸음예방 시스템에 활용한다면 졸음운전 사고로 인한 사망률을 낮추는데 기여할 수 있을 것으로 기대된다.

• 농업과학연구
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• 제43권2호
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• pp.205-214
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• 2016

A drought-tolerant transgenic rice (Agb0103) was developed using a pepper methionine sulfoxide reductase (CaMsrB2) under the control of rice Rab21 promoter with a selection marker, the phosphinothricin acetyltransferase (PAT) gene. Commercialization of genetically modified (GM) crops will require the evaluation of risks associated with the release of GM crops. With the potential problems associated to GM crops safety testing, the investigation of their effects on non-target organisms is necessary for environmental risk research. This study was carried out to assess acute toxicity of a GM crop using the water flea (Daphnia magna) for non-target organism risk evaluation. The effect of acute toxicity on Daphnia magna of Agb0103 rice and a non-GM rice, Ilmibyeo, were investigated at different concentrations (0, 625, 1,250, 2,500, 5,000, and 10,000 mg/L). The Agb0103 rice used for the test was confirmed to express the CaMsrB2/PAT gene by the PCR and ELISA. Daphnia magna feeding tests showed no significant differences in cumulative immobility or abnormal response with either Agb0103 rice or non-GM rice. The 48hr-EC50 values showed no difference between Agb0103 rice (2243 mg/L) and non-GM rice (2694 mg/L). These results suggest that there is no significant difference in toxicity to Daphnia magna between Agb0103 rice and its non-GM counterpart.

• Asian Pacific Journal of Cancer Prevention
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• 제15권5호
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• pp.2345-2351
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• 2014

Lysyl oxidase-like 2 (LOXL2), a member of the lysyl oxidase (LOX) family, is a copper-dependent enzyme that catalyzes oxidative deamination of lysine residues on protein substrates. LOXL2 was found to be overexpressed in esophageal squamous cell carcinoma (ESCC) in our previous research. We later identified a LOXL2 splicing variant LOXL2-delta72 and we overexpressed LOXL2-delta72 and its wild type counterpart in ESCC cells following microarray analyses. First, the differentially expressed genes (DEGs) of LOXL2 and LOXL2-delta72 compared to empty plasmid were applied to generate protein-protein interaction (PPI) sub-networks. Comparison of these two sub-networks showed hundreds of different proteins. To reveal the potential specific roles of LOXL2- delta72 compared to its wild type, the DEGs of LOXL2-delta72 vs LOXL2 were also applied to construct a PPI sub-network which was annotated by Gene Ontology. The functional annotation map indicated the third PPI sub-network involved hundreds of GO terms, such as "cell cycle arrest", "G1/S transition of mitotic cell cycle", "interphase", "cell-matrix adhesion" and "cell-substrate adhesion", as well as significant "immunity" related terms, such as "innate immune response", "regulation of defense response" and "Toll signaling pathway". These results provide important clues for experimental identification of the specific biological roles and molecular mechanisms of LOXL2-delta72. This study also provided a work flow to test the different roles of a splicing variant with high-throughput data.

• 한국콘텐츠학회논문지
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• 제12권9호
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• pp.182-193
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• 2012

벨소리와 통화연결음 시장의 확대에 주목하여 음원소비가 감상용 음원에서 꾸미기용 음원으로의 활용 확대되는 시점에서 발신자와 수신자가 음원에 대하여 브랜드개성으로 인식하는지, 자아표현이 어떠한 방식으로 이루어 질 것인가에 관한 연구이다. 대학생 196명을 대상으로 본인의 자아이미지와 본인이 선택 혹은 선택 예정인 벨소리와 통화연결음이 일치하는지에 대한 설문조사를 실시하였다. 표본을 대상으로 SPSS 19.0 통계패키지를 사용하여 대응표본 t테스트를 실시한 결과 자아이미지의 요인으로 도출된 내향성, 외향성과 벨소리, 통화연결음의 요인으로 도출된 내향성과 외향성의 관계가 서로 불일치하였다. 즉 내향성을 가진 소비자는 외향적인 음원을, 외향적인 소비자는 내향적인 음원을 선택하고 있었다. 휴대전화 발신자는 벨소리와 통화연결음 등 음원을 선택함에 있어 본인이 아닌 상대방을 염두에 두어 본인의 자아이미지와 상반되는 브랜드개성을 가진 음원을 선택하는 즉 과시적 소비성향을 보여주고 있다.

• Food Science and Biotechnology
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• 제15권1호
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• pp.5-12
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• 2006

Degradation performance of environmentally friendly plastics that can be disintegrated by combination of sunlight, microbes in soil, and heat produced in landfills was evaluated for use in industries. Two multi-degradable master batches (MCC-101 and MCC-102 were manufactured, separately mixed with polyethylene using film molding machine to produce 0.025 mm thick films, and exposed to sunlight, microbes, and heat. Low- and high-density polyethylene (LDPE and HDPE) films containing MCC-101 and MCC-102 became unfunctional by increasing severe cleavage at the surface and showed high reduction in elongation after 40 days of exposure to ultraviolet light. LDPE and HDPE films showed significant physical degradation after 100 and 120 days, respectively, of incubation at $68{\pm}2^{\circ}C$. SEM images of films cultured in mixed mold spore suspension at $30^{\circ}C$ and 85% humidity for 30 days revealed accelerated biodegradation on film surfaces by the action of microbes. LDPE films containing MCC-l01 showed absorption of carbonyls, photo-sensitive sites, at $1710\;cm${-1}$ when exposed to light for 40 days, whereas those not exposed to ultraviolet light showed no absorption at the same frequency. MCC-101-based LDPE films showed much lower $M_w$ distribution after exposure to UV than its counterpart, due to agents accelerating photo-degradation contained in MCC-101.

• 소성∙가공
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• 제24권3호
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• pp.205-211
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• 2015

The current investigation was performed to study sliding-wear-rate deviation (wear-rate data scatter) in carbon steels with various microstructures. Pure iron, 0.2 wt. % C steel, 0.45 wt. % C steel, and bearing steel (AISI52100) were used for the investigation. These steels possess different microstructures. Microstructures of the pure iron, two carbon steel and the bearing steel were full ferrite, ferrite + pearlite and full pearlite, respectively. Depending on the carbon content, the carbon steel had different pearlite-volume fractions. Dry sliding wear tests of the steel were conducted using a ball-on-disk wear tester at a sliding speed of 0.1 m/s using a bearing ball (AISI52100) as a counterpart. Applied load and sliding distance were 100 N and 300 m, respectively. More than three (up to twelve) tests were conducted for each steel under the same conditions, and the mean deviations in the wear rate of the steel (microstructure) were compared. The wear-rate deviation in the steel with ferrite + pearlite microstructure was higher than that with ferrite microstructure, and the deviation decreased with the increase of pearlite volume fraction. The pure iron and the bearing steel specimens showed much less deviation. The high deviation observed from the ferrite + pearlite steel was attributed to irregular subsurface-crack nucleation and growth at the interface between the two micro constituents (ferrite and pearlite) during the wear test.