• Title/Summary/Keyword: Cost-utility analysis

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Comparing Endoscopy and Upper Gastrointestinal X-ray for Gastric Cancer Screening in South Korea: A Cost-utility Analysis

  • Chang, Hoo-Sun;Park, Eun-Cheol;Chung, Woo-Jin;Nam, Chung-Mo;Choi, Kui-Son;Cho, Eun;Cho, Woo-Hyun
    • Asian Pacific Journal of Cancer Prevention
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    • v.13 no.6
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    • pp.2721-2728
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    • 2012
  • Background: There are limited data evaluating the cost-effectiveness of gastric cancer screening using endoscopy or upper gastrointestinal x-ray in the general population. Objective: To evaluate the cost-effectiveness of population-based screening for gastric cancer in South Korea by decision analysis. Methods: A time-dependent Markov model for gastric cancer was constructed for healthy adults 30 years of age and older, and a deterministic sensitivity analysis was performed. Cost-utility analysis with multiple strategies was conducted to compare the costs and effects of 13 different screening alternatives with respect to the following eligibility criteria: age at the beginning of screening, screening interval, and screening method. The main outcome measurement was the incremental cost-effectiveness ratio. Results: The results revealed that annual endoscopic screening from ages 50-80 was the most cost-effective for the male population. In the females, biennial endoscopy screening from ages 50-80 was calculated as the most cost-effective strategy among the 12 screening alternatives. The most cost-effective screening strategy may be adjustable according to the screening costs and the distribution of cancer stage at screening. The limitation was that effectiveness data were obtained from published sources. Conclusions: Using the threshold of $19,162 per quality-adjusted life year on the basis of the Korean gross domestic product (2008), as suggested by the World Health Organization, endoscopic gastric cancer screening starting at the age of 50 years was highly cost-effective in the Korean population. The national recommendation for gastric cancer screening should consider the starting age of screening, the screening interval, and the screening modality.

A Systematic Review of Economic Analysis on Idiopathic Short Stature (특발성 저신장의 경제성 평가 연구 경향 분석: 체계적 문헌고찰)

  • Lee, Boram;Kwon, Chan-Young;Jang, Soobin
    • The Journal of Pediatrics of Korean Medicine
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    • v.35 no.2
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    • pp.1-10
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    • 2021
  • Objectives We aimed to examine health-related economic analysis of available interventions on idiopathic short stature (ISS). Methods Eight studies were reviewed from English, Korean, and Chinese databases which were published up to December 24, 2020. Effectiveness, utility, and cost data were extracted from the studies and descriptive analysis of the individual studies was conducted Results Five studies were chosen. In the two economic evaluation studies, the incremental cost-effectiveness ratio (ICER) of growth hormone (GH) treatment was presented by performing cost-effectiveness analysis based on the deterministic decision tree approach for the GH and untreated group. Final adult height and direct medical costs were analyzed as effectiveness and cost outcomes. In 1 review article, an ICER of GH was presented based on systematic review on the effects of the GH treatment. In the two clinical trials, the effectiveness and cost of the 12 months Oriental medicine combination treatment were presented in comparison with the GH treatment alone. There were no literatures that provided utility data of available intervention on ISS. Conclusions The results of this study will be used as basic data for the economic analysis of Oriental medicine treatment on ISS in the future.

A Scoping Review for Economic Evaluation of Korean Medicine for Whiplash Associated Disorders (교통사고 상해증후군의 한의치료에 대한 경제성평가를 위한 주제범위 문헌고찰)

  • Kang, Shin-Woo;Hwang, Yun Gyeong;Hwang, Man-Suk;Lee, Hye-Yoon
    • The Journal of Churna Manual Medicine for Spine and Nerves
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    • v.16 no.2
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    • pp.97-105
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    • 2021
  • Objectives This study is aimed to evaluate cost-effectiveness of treatment of Korean Medicine for whiplash associated disorders (WAD) and to suggest the direction of future research. Methods We searched papers in Pubmed database to use some keywords indicating whiplash injury syndrome, treatment of Korean Medicine and cost-effectiveness. After searching, appropriate papers were selected depending on the exclusion criteria. The selected papers were analyzed in the sections of author, publication year, intervention and control groups, outcome measurement, the list including in the cost, cost-effectiveness, cost-utility and study design. Results Four studies about effect of Korean medicine and 3 studies about economic evaluation were finally included. Acupuncture was effective for balance disorder and neck pain. Economic evaluation studies used analytical decision model or cost-consequence analysis. Cost-effectiveness analysis using visual analog scale and cost-utility analysis using quality adjusted life years were performed. Initiating timing of proper management affected the consequence of treatments. Direct and indirect medical costs including supportive devices, and non-medical costs such as litigation were considered. Conclusions We conclude that studies haven't been conducted so far to evaluate the cost-effectiveness of Korean Medicine in whiplash injury syndrome. Thus, future studies are needed in this section.

Performance Evaluation Model for Future Weapon Systems (미래무기체계의 성능평가모형)

  • 김의환;최규명;정창모;김종윤
    • Journal of the military operations research society of Korea
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    • v.23 no.2
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    • pp.15-24
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    • 1997
  • In this paper we suggested a performance evaluation model for future weapon systems. Weapon Performance Index(WPI) model transform the characteristics of alternatives as indices. We can easily obtain WPIs of alternatives with the model. The highest WPI recommended as the best solution. The performance elements in hierachy for future weapon systems are determined by systems engineering procedure. Priorities in hierachy can be determined through survey of experts engineering procedure. Priorities in hierachy can be determined through survey of experts and statistical analysis. Utility function is formulated as a probability model and utility score is predicted on the basis of historical data about the same category of weapon systems in the world. WPI is calculate from sum of product of priorities and utility scores. The model can be applied to trade-off analysis, cost and effectiveness analysis, war game model.

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An Exploratory Study for the Telecommunications Service Failure Cases in South Korea (정보통신 서비스의 실패 요인: 한국의 텔레콤 서비스시장에서의 실패사례연구)

  • 안재현;권재원;김명수;이동주;이상윤;한상필
    • Journal of the Korean Operations Research and Management Science Society
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    • v.27 no.3
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    • pp.115-133
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    • 2002
  • In this paper, 15 South Korean telecommunications service failure cases were analyzed. Through the in-depth case study, 8 factors were found to be the major causes contributing to the telecommunications service failure. They were (1) ineffective marketing, (2) poor demand forecasting due to misjudgment of customer preference, (3) failure to satisfy technical specifications, (4) loss of cost advantage due to the price cut of competing services or new entry with lower price, (5) loss of utility advantage due to the increased utility of competing services or new entry with higher utility (6) decrease of market attractiveness due to change of customer preference, (7) impact of government policy, and (8) insufficient or low quality of contents. Additional analysis was done to derive managerial implications to the new telecommunications service development strategy. The findings from the paper will provide valuable Insight to the successful Implementation of new service development and service provisioning processes.

Utility of Nuclear Morphometry in Effusion Cytology

  • Ambroise, Marie Moses;Jothilingam, Prabhavati;Ramdas, Anita
    • Asian Pacific Journal of Cancer Prevention
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    • v.15 no.16
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    • pp.6919-6922
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    • 2014
  • Background: The cytological analysis of serous effusions is a common investigation and yields important diagnostic information. However, the distinction of reactive mesothelial cells from malignant cells can sometimes be difficult for the cytopathologist. Hence cost-effective ancillary methods are essential to enhance the accuracy of cytological diagnosis. The aim of this study was to examine the utility of nuclear morphometry in differentiating reactive mesothelial cells from malignant cells in effusion smears. Materials and Methods: Sixty effusion smears consisting of 30 effusions cytologically classified as malignant (adenocarcinomas) and 30 benign effusions showing reactive mesothelial cells were included in the study. ImageJ was used to measure the nuclear area, perimeter, maximal feret diameter, minimal feret diameter and the circularity. A total of ten representative cells were studied in each case. Results: Significant differences were found between benign and malignant effusions for the nuclear area, perimeter, maximal feret diameter and minimal feret diameter. No significant difference was found for circularity, a shape descriptor. Receiver operating characteristic (ROC) curve analysis revealed that nuclear area, perimeter, maximal feret diameter, and minimal feret diameter are helpful in discriminating benign and malignant effusions. Conclusions: Computerised nuclear morphometry is a helpful ancillary technique to distinguish benign and malignant effusions. ImageJ is an excellent cost effective tool with potential diagnostic utility in effusion cytology.

A Study on the Effect of Travel Time and Cost by Means on the Mode and Destination Choice of a Commuter by the Household Income Class - Based on the Utility-Based Accessibility Approach - (통행수단별 소요시간과 비용이 가구소득계층별 통근통행자의 수단 및 목적지 선택에 미치는 영향 분석 - 효용기반 접근도 개념에 근거하여 -)

  • Jang, Seongman
    • Journal of Korea Planning Association
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    • v.54 no.1
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    • pp.52-66
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    • 2019
  • Travel is a factor that stimulates the vitality of the urban and is widely used as an indicator of sustainable growth of the region. In Korea, however, no studies has been made to predict changes in traffic and calculate the accessibility of the region by comprehensively considering the socio-economic conditions of the travelers. The purpose of this study is to classify commuters according to the household income and to analyse the traffic characteristics of each class. The analysis results are aggregated into two. First, the analysis of study found different transport characteristics for different income classes. This is the result that underpins the argument of a previous study that suggested that a discriminatory approach is necessary for each income in determining the accessibility of the region. Second, this study calculated utility values differently for each income class based on the transit time and cost required between each zone. Through these measures, transport characteristics were analyzed by income class using indicators that considered transportation infrastructure, and socio-economic conditions of the travelers. This study is meaningful in that it provided the basis for calculating the accessibility that could take into account the activities of the housing consumers in establishing domestic housing policies.

Economic Evaluation of Ramosetron in Male Patients with Diarrhea-predominant Irritable Bowel Syndrome in Korea (설사형 과민성 장 증후군 남성 환자에게 사용되는 ramosetron 의 경제성 평가)

  • Sohn, Hyun-Soon;Lee, Tae-Jin;Kim, Sun
    • Korean Journal of Clinical Pharmacy
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    • v.20 no.3
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    • pp.268-277
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    • 2010
  • This study was conducted to analyze the cost-utility of ramosetron monotherapy, trimebutine monotherapy and trimebutine+loperamide combination therapy in male diarrhea-predominant patients with irritable bowel syndrome (IBS) in Korean healthcare setting. We constructed a decision-analytical model to estimate both total costs for each state of health and outcomes such as IBS-symptoms improvement for 3 and 6 months time horizon. Base analysis found that for ramosetron treatment with the price of KW910 for 5 ${\mu}g$ tablet, incremental cost effectiveness ratios (ICERs, cost per quality-adjusted life day) were KW85,000 and KW62,000 for 3 months and 6 months, respectively, compared with trimebutine. But ramosetron was a dominant strategy when compared with trimebutine+loperamide for both 3 months and 6 months. Sensitivity analyses showed robust results for drug acquisition costs till ramosetron price of KW950/tablet. In conclusion, ramosetron was a cost-effective regimen compared with trimebutine or trimebutine+loperamide from the societal perspective.

A Modified EGEAS Model with Avoided Cost and the Optimization of Generation Expansion Plan (회피비용을 고려한 EGEAS 모형 개발과 전원개발계획의 최적화)

  • 이재관;홍성의
    • Journal of the Korean Operations Research and Management Science Society
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    • v.17 no.1
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    • pp.117-117
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    • 1992
  • Pubilc utility industries including the electric utility industry are facing a new stream of privatization com-petition with the private sector and deregulation. The necewssity to solve now and in the future power supply and demand problems has been increasing through the sophisticated generation expansion plan(GEP) approach con-sidering not only KEPCo's supply-side resources but also outside resources such as non-utility generation(NUG) demand-side management (DSM). Under the environmental situation in the current electric utility industry a new approach is needed to acquire multiple resources competitively. This study presents the development of a modified electric generation expansion analysis system(EGEAS) model with avoided cost based on the existing EGEAS model which is a dynamic program to develope an optimal generation expansion plan for the electric utility. We are trying to find optimal GEP in Korea's case using our modified model and observe the difference for the level of reliabilities such as the reserve margin(RM) loss of load probability(LOLP) and expected unserved energy percent(EUEP) between the existing EGEAS model and our model. In addition we are trying to calculate avoided cost for NUG resources which is a criterion to evaluate herem and test possibility of connection calculation of avoided cost with GEP implementation using our modified model. The results of our case study are as follows. First we were able to find that the generation expansion plan and reliability measures were largely influenced by capacity size and loading status of NUG resources, Second we were able to find that avoided cost which are criteria to evaluate NUG resources could be calculated by using our modified EGEAS model with avoided cost. We also note that avoided costs were calculated by our model in connection with generation expansion plans.

An Analysis of Best Practices for Efficient Utility Relocation and an Inquiry into the Applicability of SUE (효율적인 지하지장물 이설을 위한 모범사례분석 및 SUE 적용에 관한 연구)

  • Lee, Seung-Hyun;Baek, Seung-Ho;Tae, Yong-Ho;Ahn, Bang-Ryul;Park, Hyeon-Yong
    • Proceedings of the Korean Institute Of Construction Engineering and Management
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    • 2007.11a
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    • pp.971-976
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    • 2007
  • In the U.S., utility damages or utility delay caused by conflicts during the underground utility relocation is one of the weighty problem in the construction industry. Also, in domestic case, delay and additional cost caused by underground utility(i.e, electricity, communication, gas, water supply and sewerage) relocation has been happened so that there is an increase of claims for responsibility between owners and contractors. However, there is insufficient survey for the recent circumstance of additional cost for delay and design changes caused by utility relocation and shortage of enough research for solving and analyzing of causes and their ripple effect. This research presents a result of the study about the best practices of FHWA(Federal Highway Administration), SHAs(State Highway Agencies) and the utility companies managing utility relocation. Also, it presents the basic concept of SUE(Subsurface Utility Engineering), the most reliable tool of FHWA presented, and investigates the developing status about SUE in Korea. At the end of this paper, this research proposes a practical and more applicable study about the efficient utility relocation focusing on local industry.

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