• Journal of Animal Science and Technology
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• v.63 no.3
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• pp.603-613
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• 2021

This research improved the growth potential of Bifidobacterium animalis subsp lactis strain JNU306, a commercial medium that is appropriate for large-scale production, in yeast extract, soy peptone, glucose, L-cysteine, and ferrous sulfate. Response surface methodology (RSM) was used to optimize the components of this medium, using a central composite design and subsequent analyses. A second-order polynomial regression model, which was fitted to the data at first, significantly lacked fitness. Thus, through further analyses, the model with linear and quadratic terms plus two-way, three-way, and four-way interactions was selected as the final model. Through this model, the optimized medium composition was found as 2.8791% yeast extract, 2.8030% peptone soy, 0.6196% glucose, 0.2823% L-cysteine, and 0.0055% ferrous sulfate, w/v. This optimized medium ensured that the maximum biomass was no lower than the biomass from the commonly used blood-liver (BL) medium. The application of RSM improved the biomass production of this strain in a more cost-effective way by creating an optimum medium. This result shows that B. animalis subsp lactis JNU306 may be used as a commercial starter culture in manufacturing probiotics, including dairy products.

• Particle and aerosol research
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• v.18 no.3
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• pp.61-68
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• 2022

In this study, a fluidized bed particle generator was developed to generate an aerosol without supply of compressed air and to increase portability. It was assumed that the mixing ratio of the test particles and beads, the input amount, and the air flow rate supplied to the generator would have effect on the aerosol generation characteristics. The product of these three parameters was set as a characteristic parameter and particle generation characteristics according to the change of the characteristic parameter were observed. As a result, it was confirmed that the input amount of test particles and beads was not suitable as a characteristic parameter and a characteristic parameter expressed as a product of the mass mixing ratio and the air flowrate was newly defined. When the new characteristic parameter is applied, it can be confirmed that the total amount of particles generated from the particle generator is a function of the characteristic parameter. As a result of measuring the amount of particle generation by adjusting the characteristic parameter, it was confirmed that the performance required for the test particle generator for the field inspection equipment of PM-2.5 sensors could be satisfied.

• Korean Journal of Construction Engineering and Management
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• v.11 no.2
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• pp.94-105
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• 2010

Recently, resettlement problems of low income groups in the urban regeneration area have been issued in Korea because they have no capability to purchase (or lease) redeveloped housing (or apartment). There are several approaches for supplying affordable housing and one of these is the bidding system which can reduce construction cost. However, the lowest bidding system has many problems such as dumping and substandard quality. In this context, this study proposed bidding system based on technical proposal applying the concept of the lowest total combined bid price for optimization of bid price, reduction of construction cost and period, and maintenance of suitable quality. This bidding system embraces the best value and cost plus time concept on the basis of an improved lowest price bidding system. It consists of the following components: work unit based, project unit based, and period reducing technical proposals. The proposed bidding system for determining bidders are designed to evaluate the adequacy of each technical proposal in the order of the combined minimum price in an effort to effectively optimize bid prices and reduce the construction periods, as well as to maintain a minimum appropriate quality.

• Journal of Digital Convergence
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• v.15 no.4
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• pp.127-137
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• 2017

The role of smartphones is changing from a communication system for exchanging calls and information into a universal platform for cultural services. Also, satisfaction for mobile application services on smartphones is a very important factor in the smart business. In This paper, we analyze the effects of the outcome, service scape, costs, and especially the impact of whether costumers having to pay or free for the app on customer satisfaction. For this purpose, we analyzed survey data on service quality of mobile app service from Chinese mobile app service users. We also analyzed the moderating effects of paid and free mobile app services. As a result, it was confirmed that the quality, servicescape quality and cost of mobile app service that customers perceive have a positive effect on customer satisfaction. In addition, the effect of the cost of mobile app service perceived by the customer on customer satisfaction showed that free mobile app service was more significant than paid mobile app service. This paper can be used as an alternative to monetization for providing a mobile app service provider or a mobile app service provider who wants to switch mobile app service from free to paid service.

• Journal of the Institute of Electronics and Information Engineers
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• v.53 no.5
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• pp.13-18
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• 2016

In Long Term Evolution-Advanced (LTE-A), small cell enhancement(SCE) has been developed as a cost-effective way of supporting exponentially increasing demand of wireless data services and satisfying the user quality of service(QoS). However, there are many problems such as the transmission rate and transmission quality degradation due to the dense and irregular distribution of a large number of small cells. In this paper, we propose a clustering based interference management scheme in dense small cell network. We divide the small cells into different clusters according to the reference signal received power(RSRP) from user equipment(UE). Within a cluster, an almost blank subframe(ABS) is implemented to mitigate interference between the small cells. In addition, we apply the power control to reduce the interference between the clusters. Simulation results show that proposed scheme can improve Signal to Interference plus Noise Ratio(SINR), throughput, and spectral efficiency of small cell users. Eventually, proposed scheme can improve overall cell performance.

• Asian Spine Journal
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• v.12 no.6
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• pp.973-980
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• 2018

Study Design: Retrospective review. Purpose: To identify the trends in stimulator use, pair those trends with various grafting materials, and determine the influence of stimulators on the risk of revision surgery. Overview of Literature: A large number of studies has reported beneficial effects of electromagnetic energy in healing long bone fractures. However, there are few clinical studies regarding the use of electrical stimulators in spinal fusion. Methods: We used insurance billing codes to identify patients with lumbar disc degeneration who underwent anterior lumbar interbody fusion (ALIF). Comparisons between patients who did and did not receive electrical stimulators following surgery were performed using logistic regression analysis, chi-square test, and odds ratio (OR) analysis. Results: Approximately 19% of the patients (495/2,613) received external stimulators following ALIF surgery. There was a slight increase in stimulator use from 2008 to 2014 (multi-level $R^2=0.08$, single-level $R^2=0.05$). Patients who underwent multi-level procedures were more likely to receive stimulators than patients who underwent single-level procedures (p<0.05; OR, 3.72; 95% confidence interval, 3.02-4.57). Grafting options associated with most frequent stimulator use were bone marrow aspirates (BMA) plus autograft or allograft for single-level and allograft alone for multi-level procedures. In both cohorts, patients treated with bone morphogenetic proteins were least likely to receive electrical stimulators (p<0.05). Patients who received stimulation generally had higher reimbursements. Concurrent posterior lumbar fusion (PLF) (ALIF+PLF) increased the likelihood of receiving stimulators (p<0.05). Patients who received electrical stimulators had similar revision rates as those who did not receive stimulation (p>0.05), except those in the multilevel ALIF+PLF cohort, wherein the patients who underwent stimulation had higher rates of revision surgery. Conclusions: Concurrent PLF or multi-level procedures increased patients' likelihood of receiving stimulators, however, the presence of comorbidities did not. Patients who received BMA plus autograft or allograft were more likely to receive stimulation. Patients with and without bone stimulators had similar rates of revision surgery.

• Journal of Korean Society for Quality Management
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• v.11 no.1
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• pp.10-17
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• 1983

This paper studies item-life test plans with the specified item mean life $T_1$ (MTBF) - Producer's risk ${\alpha}$ and item mean life $T_2$ (MTBF, $T_2$ < $T_1$) - Consumer's risk ${\beta}$ when the probability of item survival follows the Weibull distribution (known shape parameter) as a expansion of [1]. And Operating Characteristic Curves and Average Life-testing Times of item-life test plans are computed for this paper and [1]. Cost analysis procedures are same as [1]. These results are computed by using computer program written in Level II Basic for Apple II Plus Micro-computer. Both this paper and [6] reduce the life-testing time for Weibull distribution in comparision with Exponential distribution, but results of [6] were computed for different criterions from this paper.

• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• v.31 no.5
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• pp.417-421
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• 2005

This study was to analyze the changes of levels of alkaline phosphatase before and after enucleation of jaw cysts combined with bone grafting, and to evaluate biochemically the effectiveness of the early detection of bone healing and infection as a prognostic marker. Eighteen patients (13 males, 5 females) with cystic lesions of the jaws were divided into two groups. The bone graft group underwent enucleation and bone graft. The control group underwent only enucleation. Both groups were measured levels of ALP before surgery, and plus-minus 4 weeks postoperatively. The more discriminating results were obtained in the bone graft group. The results were as follows : 1. Levels of ALP after enucleation of jaw cysts were decreased in all patients with and without bone graft. 2. The bone graft group showed more marked decrease in variation of levels of ALP than the control group.(p=0.008) This should be considered as a result of increased osteoblastic activity and new bone formation. 3. Such variation could be used as a prognostic marker for bone healing after cyst operation. In the cost/benefit ratio, measurement of ALP activity could be useful as a convenient procedure in routine clinical practice.

• Journal of the Korean Institute of Illuminating and Electrical Installation Engineers
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• v.16 no.1
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• pp.67-75
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• 2002

This paper presents a PLD design of Gray Mode Graphic STN LCD drive circuit using PC interface. The proposed LCD drive circuit doesn\`t use microprocessor for the convenience of users. Thus, the LCD drive circuit can transfer efficiently image data created under PC to LCD. The LCD drive circuit which is modelled in schematic capture, AHDL and VHDL is simulated in functionally through the use of ALTERA MAX+PLUS II. Also, timing simulation is performed by ALTERA EPM7192SQC160-15 PLD implementation. The PC interface part have been programmed in MS-Visual C++ 6.0. The validity and efficiency of the proposed LCD drive circuit have been verified by test board. After comparing this LCD drive circuit to specify it was verified that the developed LCD drive circuit showed good performances, such as convenience of users, low cost.

• Smart Structures and Systems
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• v.3 no.2
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• pp.189-200
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• 2007

As a functional material, shape memory alloy (SMA) has attracted much attention and research effort to explore its unique properties and its applications in the past few decades. Some of its properties, in particular the electrical resistance (ER) based self-sensing property of SMA, have not been fully studied. Electrical resistance of an SMA wire varies during its phase transformation. This variation is an inherent property of the SMA wire, although it is highly nonlinear with hysteresis. The relationship between the displacement and the electrical resistance of an SMA wire is deterministic and repeatable to some degree, therefore enabling the self-sensing ability of the SMA. The potential of this self-sensing ability has not received sufficient exploration so far, and even the previous studies in literature lack generality. This paper concerns the utilization of the self-sensing property of a spring-biased Nickel-Titanium (Nitinol) SMA actuator for two applications: ER feedback position control of an SMA actuator without a position sensor, and estimation of the opening of a SMA actuated valve. The use of the self-sensing property eliminates the need for a position sensor, therefore reducing the cost and size of an SMA actuator assembly. Two experimental apparatuses are fabricated to facilitate the two proposed applications, respectively. Based on open-loop testing results, the curve fitting technique is used to represent the nonlinear relationships between the displacement and the electrical resistance of the two SMA wire actuators. Using the mathematical models of the two SMA actuators, respectively, a proportional plus derivative controller is designed for control of the SMA wire actuator using only electrical resistance feedback. Consequently, the opening of the SMA actuated valve can be estimated without using an extra sensor.