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Effects of Moschus, Bovis Calculus, Ursi Fel Aqua-acupuncture on Liver Damage Induced by Radix Aconiti (사향(麝香).우황(牛黃).웅담(熊膽) 약침(藥鍼)이 부자(附子)로 유발(誘發)된 간손상(肝損傷)의 회복(恢復)에 미치는 효과(效果)에 관한 관찰(觀察))

  • Hwang, Byeong-Tae;Na, Chang-Su;Hwang, U-Jun
    • Journal of Pharmacopuncture
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    • v.1 no.1
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    • pp.1-21
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    • 1997
  • In order to investigate experimentally that effect of Moschus, Bovis Calculus, Ursi Fel aqua-acupuncture on acutely damaged liver of rats induced by radix aconiti, the author gave Moschus, Bovis Calculus, Ursi Fel aqua-acupuncture according to method of manufacture stimulation to corresponding points, Kan-su(B18) and Ki-mun(Liv14), and carried out hematological, serological observation. Experimental groups were divided into 2 group : the one group was injected with extracted solution prepared by distillation method (A aqua-acupuncture treatment group), the other group was injected with extracted solution prepared by alchol extraction method (B aqua-acupuncture treatment group). The following results were obtained : 1. WBC level was decreased significantly in the experimental groups at 12, 24 and 48 hours as compared with the control group. RBC and hemoglobin levels were not changed significantly in the experimental groups. 2. Total cholesterol level was decreased significantly in the experimental groups at 12, 24 and 48 hours as compared with the control group. ALP level was decreased significantly in the experimental groups at 6 and 24 hours as compared with the control group. ${\gamma}-GTP$ level was decreased significantly in the experimental groups at 6, 12, 24 and 48 hours as compared with the control group. 3. GOT level was decreased significantly in the experimental groups at 6 and 12 hours as compared with the control group. GPT level was decreased siginificantly in the experimental groups at 12, 24 and 96 hours as compared with the control group. According to the above findings, it is considered that Moschus, Bovis Calculus, Ursi Fel aqua-acupuncture has effects of recovery of acutely damaged liver.

Reproducibility of physiological patterns in disgust visual stimulation design

  • Lee, Kyung-Hwa;E. Sokhadze;Jang, Eun-Hye;Yang, Gyung-Hye;Sohn, Jin-Hun
    • Proceedings of the Korean Society for Emotion and Sensibility Conference
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    • 2000.11a
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    • pp.73-80
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    • 2000
  • The paper is addressed to the topic of physiological response-specificity in disgust induced by visual stimulation. The purpose of this study was to evaluate reproducibility of physiological reactivity pattern during disgust elicited by the International Affective Pictures System (IAPS) in 2 experiments. Twenty-nine subjects participated in the first experiment with 3 visual stimulation sessions with disgust-eliciting slides (3 slides in each 1 min long session). In the second experiment disgust-eliciting slides from the IAPS were presented to 42 subjects in 2 sessions (one slide for 1 min). Spectral power of frontal EEG, skin conductance (SCL, SCR and NS.SCR), heart rate(HR), heart period variability(HPV) and respiration rate were recorded. Visual stimulation evoked 1:.n deceleration, higher power of high frequency component of HPV, increased SCL and NS.SCR frequency, frontal slow alpha blocking and moderate increase in fast beta power in most of the sessions in both experiments. However in the second experiment the EEG pattern associated with disgust showed inconsistent shifts in fast alpha and slow beta bands, but was marked by higher power of theta activity. Our data in both experiments emphasizes presence of disgust-specific profiles of autonomic and at the less extent EEG responses in visual stimulation context. Discussed are potential behavioral mechanisms leading to observed physiological manifestations in disgust elicited by visual stimulation. The results support the consideration that disgust is an withdrawal type negative valence emotion associated with relatively low autonomic arousal (low HR, low amplitude SCRs with relatively high NS.SCR frequency) and moderate EEG activation signs. Obtained data showed more consistent reproducibility of disgust-specific autonomic rather than EEG response patterns during visual stimulation design.

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Chemical Compositions and Physiological Activities of Doraji(Platycodon grandiflorum) (장생 도라지의 화학성분과 생리활성)

  • 손미예;서종권;김행자;성낙주
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.30 no.4
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    • pp.717-720
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    • 2001
  • Chemical compositions and physiological activities of Platycodon grandiflorum roots grown for 4 and 24 years were investigated. Chemical compositions of P. grandiflorum roots grown for 24 years were moisture 82.7%, crude protein 1.6%, crude lipid 2.1% crude ash 0.7%. total sugar 6.0% total dietary fiber 2.3% crude saponin 3.4mg% and ascorbic acid 3.0 mg%. Contents of each components in 24 years old roots were higher than that in 4 years old roots and the most abundant mineral was potassium being 879.9mg/kg. Physiological activities of solvent extract from P. grandiflorum roots grown for 4 and 24 years were high in order of ethanol methanol and water extract. The electron-donating abilities and nitrite-scavenging effect of solvent extract of 24 years were high in order of ethanol methanol and water extract. The electron-donating abilities and nitrite-scavenging effect of solvent extract of 24 years old roots were higher than those of 4 years of old roots in the range of 10~40% respectively.

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Isolation and Identification of Anticancer Compounds from Eucommia ulmoides Leaves (두충잎의 항암성분 분리 및 동정)

  • 김종배;박정륭;전정례;차명화
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.30 no.4
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    • pp.732-738
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    • 2001
  • This study was attempted to isolate and identify the anticancer compounds from Eucommia ulmoides leaves using a human colon cancer cell line HCT-116. The petroleum ether extracts with anticancer activity was chromatographed on silica gel TLC and finally anticancer compounds was purified by HPLC. Their chemical structures were roughly elucidate by UV-VIS absorption spectral data HPLC elution pattern and FAM/MS spectroscopy. From this study these compounds were suspected to be pheophytin a formed by the removal of $Mg^{2+}$ from chlorophyll a and pyropheophytina formed by the removal of acetate group from pheophytin a respectively. To confirm the anticancer effects against HCT-116 cancer cell petroleum ether extract fractions of column chromatography and fractions separated on TLC were tested. All samples tested including the extract of petroleum ether fractions of column chromatograph and three bands (0.13,0.19,0.25) of TLC appeared to inhibit the growth of HCT-116 cancer cell however especially 0.19 and 0.25 fractions separated on TLC plate revealed the strongest effect. These results suggest that chlorophyll derivatives in Eucommia ulmoides may be potential anticancer agents against a human colon cancer cell HCT-116.

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Study on the Principles of Prescriptions of Fire and Heat of Saam Acupuncture (사암침법(舍岩鍼法)의 화열(火熱)에 대한 연구)

  • SaGong, Hee-Chan;Kim, Byung-Soo;Kang, Jung-Soo
    • Journal of Acupuncture Research
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    • v.22 no.4
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    • pp.131-141
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    • 2005
  • Objectives : Saam acupuncture has evident principles of prescription based on acupuncture tonification and purgation of Nan-gyeong but many prescriptions of Saam acupuncture are not typical patterns. This paper studies principles of prescriptions of the king fire and the premier fire. Methods : Through investigation of many medical documents concerning king fire and the premier fire, the author explained of physiological and pathological principle of king and the premier fire, also explained of interacting mechanism through five element. And The theoretical authorities of analysis are Nan-gyeong, works of Joo dan-gye and Li dong-won. Results & Conclusion : 1. The sufficiency and the control of the water is the key to treat the disease by fire. Considering the attack and the treatment of disease, heart and liver give rise to fire in its early stage and kidney and lung are the key to treatment. 2. Consequently the pathology of the disease from fire is corresponding to the theory- Yang Sufficient, Yin Deficient- of Joo dan-gye. It seems that the theory of Joo dan-gye influenced on the medical theory of Saam Acupuncture. 3. On that account I believe that the study of medical theories of the Geum and Won Dynasty that various medical theories had appeared is very available for Saam Acupuncture. At present global warming is accelerating because environmental pollution has been increasing. Therefore the damage of fire to human body will be more and more severe and extensive. Because in the future medical plants will not be free from environmental pollution, acupuncture will be very confidential treatment.

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A Study on Ego-Identity and Adjustment in Nursing Students (간호대학생의 자아정체감과 적응에 대한 연구)

  • Kim, Myeong-Hwa;Han, Sung-Suk
    • Journal of Korean Academy of Nursing Administration
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    • v.11 no.3
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    • pp.289-301
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    • 2005
  • Purpose: This study was to examine the ego-identity of nursing students and their adjustment to home and university in an effort to identify the correlation of their ego-identity to their adjustability and lay the foundation for providing better personality education to them. Method: The subjects in this study were 400 nursing students at H and S universities in south Chungcheong province. The instruments used in this study were Park A-cheong(2003)'s Korean-version Ego-Identity Inventory and Jeong Jonggweon(1998)'s Home and School Adjustment Inventory. For data analysis, SPSS/PC+ Package was used, and statistical data on frequency and percentage were obtained. Besides, t-test, one-way ANOVA and Pearson correlation coefficient were employed. Result: The findings of the study were as follows: The nursing students investigated got a 3.46 and 3.53 in ego-identity and family life adjustment respectively out of possible five points, which were both above the average. Their score in school adjustment was 2.89, which wasn't high. As for connections between general characteristics and ego-identity, their academic school year, their type of residence, presence or absence of parents and their birth order made no statistically significant differences to their ego-identity. But as to motivation of choosing nursing, the students who chose their major at their own option were the best in that regard. Their adjustment to family life made no significant differences, and regarding school adjustment, ego-identity was better among those who lived in a lodging house or dormitory(F=4.01, p<.05) and who chose their major at their own option(F=4.88, p<.01). In addition, those with better ego-identity were better adjusted to home and school. Conclusion: As the above-mentioned findings suggested that nursing educators should teach students by mapping out specific plans to enhance the ego-identity of students and facilitate their school adjustment, and full-fledged nurses should be produced by teaching students to build the right work ethics and become qualified as a professional.

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Embedded-based Power Monitoring Security Module Design (임베디드 전력 모니터링 보안 모듈 설계)

  • Yoon, Chan-Ho;Kim, Gwang-Jun;Jang, Chang-Soo
    • The Journal of the Korea institute of electronic communication sciences
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    • v.8 no.10
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    • pp.1485-1490
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    • 2013
  • The demonstration project of the electrical grid for Smart grid is progressed, the smart digital appliances AV technology, Smart home energy management technology charging the management function of complex energy for the automation management of air conditioning and heating, humidity and air, the health care technology charging the design of housing for the elderly and disabled and the measurement of individual bio information, and the Smart home security technology dealing with the biometric security and motion sensors, etc. have been studied. The power monitoring terminal which uses a variety of wired and wireless networks and protocol is the target additionally to be considered in addition to the security vulnerabilities that was occurred in the existing terminal. In this research paper, the author analyzes the cryptographic techniques corresponding to the smart meter occurred by the problems that are exposed on the outside which are vulnerable to physical attacks, and intends to propose the design of the security systems for the Smart meter terminal being able to maximize the efficiency of the terminal.

Reflex Eye Movements Induced by Stimulation of the Semicircular Canal Nerve in Rabbits (가토반규관신경자극(家兎半規管神經刺戟)에 의(依)한 반사성안구운동기전(反射性眼球運動機轉)에 관(關)하여)

  • Kim, Ki-Ho
    • The Korean Journal of Physiology
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    • v.2 no.2
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    • pp.75-81
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    • 1968
  • According to recent observations of Cohen et al. the patterns of vestibular eye movements of rabbits are different from those of cats. However, the causes of such difference of the reflex eye movements in these species are not wholly explained. While the accumulated data obtained from cats appear to be established, experimental evidences in rabbits are rather meager. The author had re-examined the reflex eye movements of rabbits and attempted to find a mechanism which causes such difference in the reflex eye movements between two species. In anesthesized rabbit, unilateral individual semicircular canal nerve was stimulated selectively with a fine insulated electrode which was inserted through a hole made on the corresponding osseous canal, under a dissecting microscope. When an individual canal nerve was stimulated, the reflex movements of both eyes were observed, photographed, and recorded kymographically. Extraocular muscles were also studied to find their morphological characteristics and to correlate them with the function of the muscles. 1. At the beginning of the stimulation, both eyes moved to a specific direction depending upon the canal stimulated, and such directional eye movements were sustained during the whole course of stimulation. Amplitude of the eye movement showed graded responses to the increasing frequency of the stimulus, reaching to the maximal response at 200-300 cps. 2. Stimulation of the unilateral horizontal canal nerve caused conjugate eye movements, which was also observed in cats and other species by other investigators. 3. Stimulation of the unilateral vertical canal nerve caused a pattern of non-conjugate eye movements, which are different from those observed in cats. Such different patterns of vestibular eye movements in two different species are ascribable to the functional difference of the inferior and superior oblique muscles.

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Cloning and Expression of the Gene Encoding Glucose Permease of the Phosphotransferase System from Brevibacterium flavum in Escherichia coli

  • Kwon, Il;Lee, Kyu-Nam;Lee, Jung-Kee;Pan, Jae-Gu;Oh, Tae-Kwang;Lee, Hyung-Hoan;Yoon, Ki-Hong
    • Journal of Microbiology and Biotechnology
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    • v.5 no.4
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    • pp.188-193
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    • 1995
  • A Brevibacterium flavum gene coding for glucose permease of the phosphoenolpyruvate-dependent phosphotransferase system (PTS) was cloned by complementing the Escherichia coli ZSCl13 mutations affecting a ptsG gene with the B. flavum genomic library. From the E. coli clone grown as red colony on a MacConkey plate supplemented with glucose as an additional carbon source, a recombinant plasmid was isolated and named pBFT93. The plasmid pBFT93 was identified as carrying a 3.6-kb fragment of B. flavum chromosomal DNA which enables the E. coli transformant to use glucose or man nose as a sole carbon source in an M9 minimal medium. The non-metabolizable sugar analogues, 2-deoxy-D-glucose (2-DG) and methyl-$\alpha$-D-glucopyranoside (MeGlc) affected the growth of ZSCl13 cells carrying the plasmid pBFT93 on minimal medium supplemented with non-PTS carbohydrate, glycerol, as a sole cabon source, while the analogues did not repress the growth of ZSCl13 cells without pBFT93. It was also found that both $2-deoxy-D-[U-^{14}C]glucose{\;}and{\;}methyl-{\alpha}-D-[U-^{14}C]glucopyranoside$ could be effectively transported into ZSCl13 cells transformed with plasmid pBFT93. Several in vivo complementation studies suggested that the B. flavum DNA in pBFT93 encodes a glucose permease specific for glucose and mannose.

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Study on Developing the Scale of Korea Citizen's Intentionality out of Inborn Ability and Mission (한국 도시민의 목적지향 성향 척도 개발을 위한 연구)

  • Sohnn, Jou-Hwan;Ha, Kyu-Soo
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.15 no.10
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    • pp.6056-6065
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    • 2014
  • The aim of this study was to develop a scale of the Korea citizen's intentionality out of their inborn ability and mission. To set up the concept of the above intentionality, there have been many academic and religious studies for reference in addition to the existing productivity, Korea elderly successful aging scale, and the scale of life qualities for review. The first 57 items for questionnaires were created thereafter. The final 27 items were confirmed, which were constantly modified by a professor of statistics and corresponding author in effective response and in removing the redundant items after the first items had been reduced to 44 preliminary items through the many an item-by-item discussions with pastors, theologians and social workers. A survey was conducted around the metropolitan area and 380 records were collected. Factor analysis to verify the validity of the measurement tool was completed, and showed that there were 6 sub-factors; "recognition of being", "autonomous life", "self-completion", "initiative", "acceptance", and "economic feasibility". In addition, reliability analysis was implemented and found to be reliable because the Cronbach's ${\alpha}$ value was 0.6 or more.