• Title/Summary/Keyword: Cornea

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A Sunglasses Design to Prevent Snow Blindness at High Altitude (설맹 방지를 위한 고소등반용 선글라스 디자인)

  • Choi, Byung-Jin;Jang, Joon-Young
    • Journal of Korean Ophthalmic Optics Society
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    • v.12 no.4
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    • pp.19-22
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    • 2007
  • Recently, the population of people exploring High Mountain trekking or expedition is increasing as an increase in the backpackers. Many accidents occurring at High Mountain above 6,000 m are the results of snow blindness. The damage of cornea and/or retina is direct cause of snow blindness. The UV intensity increases on the hand, along with the altitude caused by decrease in the atmospheric pressure, on the other hand the reflections by bright snow at high mountain area. And it increases approximately 3 times and 4 times higher than the ground level at altitude of 4,000 m and 8,000 m, respectively. The use of sunglasses is more favorable than goggles for the protection of snow blindness at High Mountains. The eye frames that have high mechanical strength and the plastic lenses which can protect UV 100% are recommended. The attachable shielding pads are needed to prevent the incident UV light reflected or scattered from the gap between glasses frame and face. The sunglasses must have flexible and long temples to wind the ears adequately for the prevention of detachment during climbing and it is recommended that the metal frame to be coated with plastics to prevent the eye surroundings from frostbite.

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Skin and Eye Irritation Test of Bovine Somatotrophine-sustained Release (BST-SR) in Rabbits (토끼에게 소성장 홀몬-서방형 제형(BST-SR)의 피부 및 안점막 자극에 관한 연구)

  • 강경선;최경철;신동진;김형욱;조재진;이영순
    • Journal of Food Hygiene and Safety
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    • v.6 no.3
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    • pp.171-177
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    • 1991
  • According to the Established Regulations of National Institute of Safety Research, the skin-irritation test of BST-SR (Lucky Ltd.) was perfonned for seven days in New Zealand White Rabbits. During treatment periods no significant clinical symptom was observed. Significant changes such as erythema, scar tissue and edema were not shown on the applicating sites. According to Primary Irritation Index of Draize, skin irritation rate was assessed as "Zero". The eye irritation of BST-SR (Lucky Ltd.) was examined in nine New Zealand White rabbits, based on the Established Regulation of National Institute of Safety Research. 0.1 ml of test material was dropped on right eye, and after 20~30 seconds, three rabbits' eyes were cleaned with wann saline for 1 minute. Other six rabbits' eyes were left uncleaned. The untreated left eyes were negative control. The lesions of cornea, iris and conjuntiva were assessed by the Grade table (from the Regulation of National Institute of Safety Research), and it is concluded that BST-SR has no eye-irritation.

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Flora and Community Structure of Benthic Marine Algae in Ilkwang Bay, Korea (한국 일광만 저서 해조류의 해조상과 군집구조)

  • Kang, Pil-Joon;Kim, Young-Sik;Nam, Ki-Wan
    • ALGAE
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    • v.23 no.4
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    • pp.317-326
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    • 2008
  • Marine algal flora and community structure were investigated seasonally at three sites in Ilkwang Bay on the southern east coast of Korea from May 2007 to February 2008. Total 103 species including 10 of green algae, 17 of brown algae, 76 of red algae were collected and identified. Among these species, 21 species were found throughout the year. Ulva pertusa, Enteromorpha linza, Grateloupia lanceolata, Chondracanthus intermedia and Caulacanthus ustulatus were distributed dominantly in upper intertidal zone. By contrast, crustose coralline algae, Grateloupia spp., Chondracanthus tenellus, Prionitis cornea and Sargassum spp. occurred predominantly in middle intertidal zone. Grateloupia spp., Sargassum spp., Ecklonia cava and Ulva pertusa were dominant in lower intertidal zone. Annual mean biomass in wet weight was 478.3 g m$^{-2}$. Maximum biomass was recorded in site 1 (731.8 g m$^{-2}$), and minimum was recorded in site 3 (78.5 g m$^{-2}$). The R/P, C/P and (R + C)/P value reflecting flora characteristics were 4.47, 0.59 and 5.06, respectively. Two groups produced by cluster analysis, one including sites 1, 2 and the other including site 3, showed meaningful difference in similarity, each other. Site 3 showed the limited species composition due to inflow of fresh water and absence of solid substratum. However, there was no significant difference between site 1 and site 2. In conclusion, the number of marine algae species and biomass in Ilkwang Bay were markedly reduced comparing with the previous studies. These suggest that a solution for reconstruction of the poor marine algal vegetation is considerably demanded.

Temporal Variation of Seaweed Biomass in Korean Coasts: Yokjido, Gyeongnam Province (한국 연안 해조류 생물량의 연간 변동 양상: 경상남도 욕지도 지역)

  • Choi, Chang-Geun;Kim, Jeong-Ha;Chung, Ik-Kyo
    • ALGAE
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    • v.23 no.4
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    • pp.311-316
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    • 2008
  • The seasonal variation of marine algal biomass and community were studied with nondestructive sampling and quadrat method during May 2006 to April 2008 in the intertidal and subtidal zone at Yokjido. As result, total 120 species, 13 Chlorophyta, 34 Phaeophyta, 71 Rhodophyta and 2 Spermatophyta were identified in this study. The major species which contributed significantly to the total biomass were Ulva pertusa, Undaria pinnatifida, Ecklonia stolonifera, Sargassum horneri, S. serratifolium, Gelidium amansii and Prionitis cornea. The mean biomass was 235.5 g wet wt m$^{-2}$ in intertidal, 1,038.9 g wet wt m$^{-2}$ in 1 m, 1,013.1 g wet wt m$^{-2}$ in 5 m, and 19.7 g wet wt m$^{-2}$ in 10 m depths of mean sea level. Seasonal biomass change in intertidal zone, the peak season was in spring, while the lowest was in autumn. The vertical distribution of marine vegetation was characterized by Ulva pertusa - Gelidium divaricatum - Gloiopeltis furcata - Sargassum thunbergii - Hizikia fusiformis at intertidal zone, and Caulerpa okamurae - Gelidium amansii - Chondrus ocellatus - Ecklonia stolonifera - Sargassum horneri - Gracilaria textorii at subtidal zone. These result indicates that the marine algal species and biomass of 1 m and 5 m depths in subtidal zone are greater than intertidal zone, and Ecklonia stolonifera and Sargassum spp. are the dominant species of Yokjido.

A Study of Ultrastructure on attachment of Soft Contact Lens Surface of Incubated Pseudomonas aeruginosa (배양된 Pseudomonas aeruginosa의 소프트 콘택트 렌즈 표면부착에 대한 미세구조적 연구)

  • Kim, Douk Hoon;Park, Yong Tae;You, Hae Byung
    • Journal of Korean Ophthalmic Optics Society
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    • v.5 no.2
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    • pp.11-14
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    • 2000
  • The soft contact lens was very simple technique in handling, good sensation in fitting, good effect of a beauty, and good attachment state on the cornea in physical movement. So that, the subjects have used the correct of visual acuity. If the contact lens handling have not skill, they have acquired the side effect on eye. To analysis of a study of ultrastructure on soft contact lens surface of incubated P. aeruginosa. We have observed the soft contact lens surface by SEM. We have founded the good technical method. On the method of sample process of manufacture, the best observation of samlpe tissue was $OsO_4$ postfixation and tannic acid treatment. In this case, P. aeruginosa was a rod shape and one cilia in ultrastructure and the identification was very good. But, On the process of manufacture have not used the $OsO_4$ and tannic acid treatment, this tissue sample appeared the foreign body materials and artifacts, and the identification of the P. aeruginosa was very difficult.

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Image Analysis Algorithm for the Corneal Endothelium

  • Kim Young-Yoon;Kim Beop-Min;Park Hwa-Joon;Im Kang-Bin;Lee Jin-Su;Kim Dong-Youn
    • Journal of Biomedical Engineering Research
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    • v.27 no.3
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    • pp.125-130
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    • 2006
  • The number of the living endothelial cells and the shape of those are very import clinical parameters for the evaluation of the quality of cornea. In this paper, we developed the automated endothelial cell counting and shape analysis algorithm for a confocal microscope. Since, the endothelial images from the confocal microscope has a non-uniform illumination and low contrast between cell boundaries and cell bodies, it is very difficult to segment the cells from the endothelial images. To cope with these difficulties, we proposed the new two stage image processing algorithm. At first stage algorithm, we used a high-pass filter and histogram equalization to compensate the non-uniform brightness pattern and a morphological filter and a watershed method are applied to detect the boundary of cells. From this stage, we could count the number of cells in an endothelial image. At second stage algorithm, we used a Voronoi diagram method to classify the shape of cells. This cell shape analysis and the percent of hexagonal cells are very sensitive in detecting the early endothelium damage. To evaluate the performance of the proposed system, we p개cessed seven endothelial images obtained using a confocal microscope. The proposed system correctly counted 95.5% cells and classified 92.0% of hexagonal cell shapes. This result is better than any others in this research area.

The Effect of Salt in Medicine for Salt Pharmacopuncture (염약침(鹽藥鍼)을 위한 소금의 의학적 효용)

  • Kim, Kee Hyun;Kim, Jee Hwa;Song, Ho Sueb
    • Journal of Acupuncture Research
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    • v.32 no.2
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    • pp.131-145
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    • 2015
  • Objectives : The purpose of this study was to demonstrate the effectiveness and availability of salt pharmacopuncture of Korean sun-dried salt and processing salt on the basis of bibliographical review. Methods : This study was done through a narrative review of related bibliography including medical books, journals, general bibliography, and web sites. Results : 1. Korean sun-dried salt is produced in the ground with soil, tiles, and pottery. Sun-dried, traditional, granulated, bamboo, and grilled salts are all appropriate for medical use. They are composed of a lower level of NaCl and unnecessary substances, and have a higher water and mineral content. 2. The 9~30 g of NaCl included in the physiological saline matches the ratio of a normal human body. However, if the saline is used for water supply, it should be improved because the recommended amount is much lower. 3. Medicine that includes NaCl is applied for lessening the congestion of the nasal cavity, alleviating cornea swelling, or for a lack of water. NaCl can also be used for washing contact lenses as well as cleaning the mucous membrane of the eyes and nose. 4. Salt relieves anger, detoxifies, induces vomiting, builds strong muscles and bones, gives energy, slows aging, and ultimately improves health. 5. Salt treats many diseases including: cardiovascular, hematosis, respirometer, obstetric, musculoskeletal, mineral supplement, eye, teeth and skin issues, etc.. However, salt is not used for treating asthma, cough, or other ailments mainly affecting the vascular system. 6. While NaCl in salt absorbs water and the vascular constriction results in higher blood pressure, the pressure induced from salt is actually a physiologically temporary rise. Rather, salt helps remove oil from the body and its potassium lowers blood pressure. Conclusions : It was suggested that salt pharmacopuncture of Korean sun-dried salt and processing salt should be made available for adjusting the physiological salt concentration and control of the Na side effects, therefore it would be useful in the treatment of diseases.

Dynamic properties of the retinal neurons by using of the intracellular recording method (세포내 기록법으로써 검출한 망막 신경원의 동적 특성)

  • 이성종;정창섭;배선호
    • Progress in Medical Physics
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    • v.9 no.2
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    • pp.95-104
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    • 1998
  • The dynamic properties of the 3rd-order neuron of the retina was investigated by using conventional intracellular recording techniques. Experiments were performed in the superfused retina-eyecup preparation of the channel catfish, Ictalurus punctatus. The cornea, iris, lens, and vitreous were removed by absorption with Kimwipe tissue under the dissection microscope thereby exposing the retina in a hemi -eyecup. The electrical signal was amplified by electrometer, viewed on oscilloscope. Regular signals from the cells were recorded on a penwriter and stored by data recorder and computer. Full-field, spot or annular light stimuli were generated on a computer monitor and focused onto the retina. Baclofen hyperpolarized the dark membrane potential, suppressed sustained component and enhanced transient component of the ON-sustained cell with a large transient component, but did not affect the surround antagonism of the cell. Baclofen selectively suppressed responses evoked by moving bar light stimuli on the ON-OFF transient cell. The results suggest that transient cells have directional selectivity in the inner retina. These dynamic properties of amacrine and ganglion cells were modulated by baclofen. Therefore, it is presumed that there is baclofen-induced directional selectivity in ON-OFF transient cells in the catfish retina.

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Audiological Findings of Congenital Ichthyosiform Dermatosis with Sensorineural Hearing Loss (난청을 동반한 선천성 어린선상 피부병의 청각학적 소견)

  • 한태희;최진택;김광현;박찬일
    • Proceedings of the KOR-BRONCHOESO Conference
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    • 1981.05a
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    • pp.40.3-41
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    • 1981
  • The ichthyosiform dermatosis is consisted of a heterogenous group of hereditary disorders. Authors report a case of 26 year old female patient who has congenital ichthyosiform dermatosis associated with sensorineural hearing loss, neovascularization of cornea, partial alopecia and abnormalities of nails and teeth. The audiological findings of this patient were as follows: 1. Bilateral severe sensorineural hearing loss. 2. SISI scores: 100% at 1, 000 Hz and 4, 000 Hz on both ear. 3. Tone decay test: 25 dB decay at 1, 000 Hz and 4, 000 Hz respectively on both ear. 4. SRTs : 85 dB on both ear. 5. Speech discrimination scores : 80% at 95 dB hearing level(MCL) on both ear. With above results, cochlear lesion is suspected in this syndrome.

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A Case Study on Swine Farms for the Planning of Gnotobiotic Pigs' Facility - Focused on Space Organization and Circulation System - (무균돼지 사육시설 계획을 위한 사례연구 - 공간구성 및 동선계획을 중심으로 -)

  • Kwon, Soon-Jung;Seong, Je-Kyung;Yeom, Su-Cheong
    • Journal of The Korea Institute of Healthcare Architecture
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    • v.12 no.1
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    • pp.49-59
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    • 2006
  • According to the increase of demand for human organs such as kidney, heart, pancreas, joint, and cornea for therapeutic transplantation, the production of alternative organs based on Gnotobiotic Pigs gains a lot of concerns all over the world. However, it is not common to design and build Gnotobiotic Pigs' facility, and there are only a few those facilities and planning principles for them. Considering the situation above, this paper tries to develop planning guidelines for space organization and circulation system of standardized Germ Free Pig's facility on the bases of case analysis. The results of this study are as follows. At first, four swine farms including a Gntobiotic Pig's facility has been analysed from the point of space organization and circulation system. Secondly, the space zoning of Gnotobiotic Pigs' facility has been proposed into 5 groups : pigs' area, adminstration area, operating room and laboratory, service area, and mechanical area. Space components of each group have been presented also. Finally, circulation system of Gnotobiotic Pigs' facility has been explored from a operational point of view. This, also, includes human circulation, pig's circulation, and goods' circulation. This study has some limitations because it does not consider the SOPs(standard operational policies) of that facility to the fullest measure and does not suggest space area of each part, either. Despite of some weaknesses, it is expected that this study can give some useful guidelines for the design and planning of Germ Free Pigs' facilities.

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