• 제목/요약/키워드: Core-Journal

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문제중심학습 개념의 환자관리 Core Skill-TLP 교육교재 개발 및 적용 (An Examples Development and Implementation of Core Skill-TLP Package in Patient Management)

  • 이영아
    • 한국응급구조학회지
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    • 제14권2호
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    • pp.25-40
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    • 2010
  • Purpose : The purpose of this study was to develop and apply a Core Skill-TLP(Core Skill-Tutorial, Laboratory, Practicum) package in Patient Management and to effect of core skill-TLP education. Methods : This study was used to developed Patient Management' Core Skill-TLP package throughout 14 steps of Core Skill-TLP package development model. Then, Core Skill-TLP Learning methodology was implemented in first year student in the undergraduate emergency medical technology, and survey was done. Results : 1. Core Skill-TLP package model was presented based on conceptual model of PBL(S-PBL). 2, The student in OSCE did significantly better in clinical patient management core skills performance. 3. As to the satisfaction of Core Skill-TLP package management, student, tutor and self-satisfaction score was 3.21, 3.42, 3.38 respectively. Conclusion : This study was suggested that Core Skill-TLP education would be necessary with well-structured package and achieved advantage of simulation and PBL.

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PMMA/PBA와 PBA/PMMA Core Shell 복합입자의 제조 - 유화제의 영향 - (Manufacture of PMMA/PBA and PBA/PMMA core Shell Composite Particles - Effect of emulsifier -)

  • 설수덕
    • 접착 및 계면
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    • 제11권3호
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    • pp.112-119
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    • 2010
  • PMMA와 PBA core 제조 시 개시제는 APS를, 유화제 SDBS의 농도를 0.01에서 0.03 wt% 일 때 전환율이 95.8과 92.3%로 가장 우수하였으며, core-shell 복합입자의 제조 시에는 SDBS의 농도 0.02 wt% 일 때 PMMA/PBA core-shell 복합입자는 전환율이 90.0%, PBA/PMMA core-shell 복합입자는 89.0%가 되었다. FT-IR 분석과 GPC에 의한 평균분자량 측정을 통해 core와 shell 단량체들이 중합되어 있음을 확인하고, 복합입자의 형태는 상온에서의 필름형성정도와 TEM 분석으로 확인하였다. DSC에 의해 유리전이온도를 측정함으로써 일반 공중합체와는 달리 2개의 유리전이온도가 존재하여 core-shell 복합입자가 형성되었음을 알 수 있고, 각각의 core-shell 복합입자의 인장강도와 신율의 측정을 통해 고기능성 접착바인더로서의 사용가능성을 확인하였다.

Hepatitis C Virus Core Protein Sensitizes Cells to Apoptosis Induced by Anti-Cancer Drug

  • Kang, Mun-Il;Mong Cho;Kim, Sun-Hee;Kang, Chi-Dug;Kim, Dog-Wan
    • Journal of Microbiology
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    • 제37권2호
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    • pp.90-96
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    • 1999
  • The core protein of the hepatitis C virus (HCV) is a multifunctional protein. The HCV core protein was reported to regulate cellular gene expression and transform primary rat embryo fibroblast cells. However, the role of the core protein in the pathogenesis of HCV-associated liver diseases is not well understood. To investigate the functional role of the core protein in cytophathogenicity, we have constructed stable expression systems of full length or truncated HCV core protein lacking the C-terminal hyderophobic domains and established HepG2 cell clones constitutively expressing the core protein. The full length core protein was localized in the cytoplasm and the C-terminal truncated core protein was localized in the nucleus. HepG2 cells expressing nuclear, truncated core protein showed elevated cell death during cultivation compared to untransfected cells and full length core-expressing cells. In the treatment with bleomycin, both cell clones expressing full length or truncated core protein appeared to be more sensitive to blemoycin than the parental HepG2 cells. These results suggest that the core protein may play a role in HCV pathogenesis promoting apoptotic cell death of infected cells.

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Designs of 10 MW Air-core and Iron-core HTS Wind Power Generators

  • Sung, Hae-Jin;Park, Minwon;Yu, In-Keun
    • Journal of Electrical Engineering and Technology
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    • 제10권2호
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    • pp.545-550
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    • 2015
  • High Temperature Superconducting (HTS) synchronous generators can be designed with either an air-core type or iron-core type. The air-core type has higher efficiency under rated rotating speed and load than the iron-core type because of the iron losses which may produce much heat. However, the total length of HTS wire in the air-core type is longer than the iron-core type because the generated magnetic flux density of the air-core type is low. This paper deals with designs of 10 MW air-core and iron-core HTS wind power generators for wind turbines. Fully air-core, partially iron-core, and fully iron-core HTS generators are designed, and various stator winding methods in the three HTS generators are also considered, such as short-pitch concentrated winding, full-pitch concentrated winding, short-pitch distributed winding, and full-pitch distributed winding. These HTS generators are analyzed using a 3D finite elements method program. The analysis results of the HTS generators are discussed in detail, and the results will be effectively utilized for large-scale wind power generation systems.

비대칭적 임베디드 멀티코어 프로세서의 성능 연구 (A Performance Study of Asymmetric Embedded Multi-Core Processors)

  • 이종복
    • 한국인터넷방송통신학회논문지
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    • 제16권1호
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    • pp.233-238
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    • 2016
  • 근래에 임베디드 프로세서의 성능을 향상시키기 위하여 멀티코어 프로세서 구조가 널리 이용되고 있다. 이러한 멀티코어 프로세서는 크게 대칭적 구조와 비대칭적 구조로 나뉘며, 비대칭적 멀티코어 프로세서가 대칭적 멀티코어 프로세서에 비하여 더욱 성능이 높고 효율적이라고 알려져 있다. 본 논문에서는 임베디드 프로세서에 대하여 이것을 확인하기 위하여, 다양한 구성을 갖는 비대칭적 임베디드 듀얼코어, 쿼드코어, 옥타코어 및 헥사데카코어 프로세서에 대하여 MiBench 벤치마크를 입력으로 하여 모의실험을 수행하여 그 성능을 측정하였다. 또한, 비슷한 하드웨어 규모의 대칭적 임베디드 멀티코어 프로세서와 비교하여 성능의 우수성을 확인하였다.

WordNet을 매개로 한 CoreNet-SUMO의 매핑 (Mapping between CoreNet and SUMO through WordNet)

  • 강신재;강인수;남세진;최기선
    • 한국지능시스템학회논문지
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    • 제21권2호
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    • pp.276-282
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    • 2011
  • CoreNet은 한-중-일 다국어 텍스트의 분석, 언어 간 변환을 포함한 자연어처리에 유용한 자원이다. CoreNet의 보다 광범위한 분야 및 응용에의 활용을 장려하고 다국어 어휘의미망으로서의 국제적 위상을 제고하기 위해 SUMO에 연결하는 작업을 하였다. CoreNet과 SUMO를 매핑하기 위해 간접 매핑과 직접 매핑 방법을 모두 사용하였는데, CoreNet-KorLex-PWN-SUMO에 이르는 간접 매핑 작업을 통하여 한국어 중심의 CoreNet과 영어로 기술된 SUMO의 언어 간 변환의 어려움을 완화하고 CoreNet 개념에 대응하는 SUMO 클래스의 재현율을 극대화하였다.

OCBT 멀티캐스트 프로토콜에서 core 노드의 분산 계층 위치 결정 (Distributed Hierarchical Location Placement of Core Nodes in the OCBT Multicast Protocol)

  • 황경호;조동호
    • 한국통신학회논문지
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    • 제25권1A호
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    • pp.90-95
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    • 2000
  • Ordered Core Based Tree (OCBT) 프로토콜에서 core 스위치의 위치는 성능에 영향을 끼치는 가장 중요한 요소이다. 본 논문에서는 여러 level의 core 스위치를 어디에 둘 것인가에 대한 방법을 연구한다. 제안된 알고리즘은 전체 네트워크는 3개의 논리적 계층-Small, Medium, Large-으로 나누어, 네트워크의 각 노드(라우터)들은 자기 이와의 다른 노드들로부터 자신의 노드까지의 최단경로 비용의 합을 계산한다. S지역에서 최소의 비용을 가지는 노드를 core노드로 만들고, 같은 M지역에 속한 S지역의 core 노드들은 다른 core 노드들로부터의 최단 경로 합을 계산해서 그 값이 가장 작은 노드가 레벨이 하나 높은 core 노드가 된다. 그리고 M지역에서의 core노드에서 같은 방법으로 가장 높은 레벨을 가지는 core노드를 정한다. 제안한 방법을 네트워크에서 core 노드를 정하는 두 가지 일반적인 방법과 비교한다. 첫 번째 방법은 random 방법으로 같은 수의 core 노드를 random하게 선정하는 방법이다. 두 번째 방법은 center 방법으로 각각의 S지역에서 중심에 가까운 노드를 core 노드로 만들고, M지역이나 L 지역에서의 core는 하위 레벨 core 중에서 해당 熾だ\ulcorner중심에 가까운 core로 결정한다. 시뮬레이션을 통하여 제안한 방법이 mean tree cost와 join latency관점에서 비교된 다른 방법들 보다 우월한 성능을 가지는 것을 확인할 수 있었다.

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Expression and Characterization of Hepatitis C Virus Core Proteins: Effects of Single Amino Acid Substitution on Protein Conformation and Subcellular Localization

  • Hwang, Soon-Bong
    • BMB Reports
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    • 제31권3호
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    • pp.281-286
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    • 1998
  • Hepatitis C virus (HCV) core proteins from two different isolates (HCV-1 and HCV-RH) were expressed in Spotioptera Jrugiperda (Sf9) insect cells. The RH core consisted of two major species of proteins (21 kDa and 19 kDa). On the other hand, the HCV-1 core was approximately 16 kDa in a SDS-PAGE gel. Both core proteins were phosphorylated in vivo on serine residues. Furthermore, the RH core but not HCV-1 core formed dimers, indicating that the protein conformation of the core in these two isolates is dfferent from one another. Immunofluorescence studies showed that the RH core was present in the cytoplasm, whereas the HCV-1 core was localized predominantly to the nucleus in recombinant baculovirus-infected insect cells. Since the major difference between the two isolates is the codon 9 of the core protein, a single amino acid substitution appears to play a major role in the protein conformation and these properties may reflect the different biological functions of core proteins in HCV-infected cells.

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Numerical comparison between lattice and honeycomb core by using detailed FEM modelling

  • Giuseppe, Pavano
    • Advances in aircraft and spacecraft science
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    • 제9권5호
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    • pp.377-400
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    • 2022
  • The aim of this work is a numerical comparison (FEM) between lattice pyramidal-core panel and honeycomb core panel for different core thicknesses. By evaluating the mid-span deflection, the shear rigidity and the shear modulus for both core types and different core thicknesses, it is possible to define which core type has got the best mechanical behaviour for each thickness and the evolution of that behaviour as far as the thickness increases. Since a specific base geometry has been used for the lattice pyramidal core, the comparison gives us the opportunity to investigate the unit cell strut angle giving the higher mechanical properties. The presented work considers a detailed FEM modelling of a standard 3-point bending test (ASTM C393/C393M Standard Practice). Detailed FEM modelling addresses to detailed discretization of cores by means of beam elements for lattice core and shell elements for honeycomb core. Facings, instead, have been modelled by using shell elements for both sandwich panels. On lattice core structure, elements of core and facings are directly connected, to better simulate the additive manufacturing process. Otherwise, an MPC-based constraint between facings and core has been used for honeycomb core structure. Both sandwich panels are entirely built of Aluminium alloy. Prior to compare the two models, the FEM sandwich panel model with lattice pyramidal core needs to be validated with 3-point bending test experimental results, in order to ensure a good reliability of the FEM approach and of the comparison. Furthermore, the analytical validation has been performed according to Allen's theory. The FEM analysis is linear static with an increasing midspan load ranging from 50N up to 500N.

스퀴즈캐스팅용 Salt Core의 제조 및 용탕침투성에 관한 연구 (A Study on the Fabrication Process and Melt Infiltration of Salt Core in Squeeze Casting Method)

  • 김기배;노상우;이호인;남태운
    • 한국주조공학회지
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    • 제17권4호
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    • pp.402-410
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    • 1997
  • Developing a salt core for squeeze casting process, two different salt cores(pure salt core and mixed salt core) were fabricated and investigated. Pure salt core was composed of 100% NaCl and mixed salt core was made by mixtures of NaCl with MgO(1%), $Na_2B_4O_7$(2%), and talc(1%) as a binder or a strengthening agent. Salt cores were compacted to various theoretical density, heat treated, and then squeeze-cast with molten Al alloy(AC8A). The compression strength of salt cores were measured and the squeeze-cast products were examined for shape retention, infiltration of molten metal into the cores, and microstructures. The shape of salt core compacted at above 75% of the theoretical density was maintained stably. The higher theoretical density of salt cores gave higher compression strength, and the compression strength of mixed salt core was higher than that of pure salt core. Namely at 90% theoretical density, the compression strength of mixed salt core was $6.3 kg/mm^2$, compared to $4.6 kgmm^2$ for pure salt core. At a squeeze casting pressure of $1000 kg/cm^2$, molten Al alloy was infiltrated into pure salt core of under 85% of the theoretical density. At squeeze casting pressure of $1000 kg/cm^2$, only mixed salt core above 90% of the theoretical density were valid, but the shape of the core was altered in the case of pure salt core at 90% of theoretical density. A key factor for developing a salt core for squeeze casting process was estimated as the ultimate compressive strength of salt core.

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