• 제목/요약/키워드: Core Center

검색결과 2,385건 처리시간 0.028초

Intercellular Trafficking of Homeodomain Proteins

  • Kim, Seon-Won;Moon, Jun-Yeon;Jung, Jin-Hee;Chen, Xiongyan;Shi, Chunlin;Rim, Yeong-Gil;Kwon, Hey-Jin;Jackson, David;Datla, Raju;Joliot, Alain;Kim, Jae-Yean
    • The Plant Pathology Journal
    • /
    • 제21권1호
    • /
    • pp.21-26
    • /
    • 2005
  • Homeotic proteins have pivotal roles during the development of both plant and animals. Many homeotic proteins exert control over cell fate in cells where their genes are not expressed, i.e., in a non-cell autonomous manner. Cell-to-cell communication, which delivers critical information for position-dependent specification of cell fate, is an essential biological process in multicellular organisms. In plants, there are two pathways for intercellular communication that have been identified: the ligand/receptor-mediated apoplastic pathway and the plasmodesmata-mediated symplasmic pathway. Regulatory proteins and RNAs traffic symplasmically via plasmodesmata and play a critical role in intercellular communication. Thus, the non-cell autonomous function of homeotic proteins can be explained by the recent discovery of cell-to-cell trafficking of proteins or RNAs. This article specifically focuses on understanding the intercellular movement of homeodomain proteins, a family of homeotic proteins.

In Vitro Formation of Protein Nanoparticle Using Recombinant Human Ferritin H and L Chains Produced from E. coli

  • RO HYEON SU;PARK HYUN KYU;KIM MIN GON;CHUNG BONG HYUN
    • Journal of Microbiology and Biotechnology
    • /
    • 제15권2호
    • /
    • pp.254-258
    • /
    • 2005
  • We have conducted in vitro reconstitution study of ferritin from its subunits FerH and FerL. For the reconstitution, FerH was produced from an expression vector construct in Escherichia coli and was purified from a heat treated cell extract by using one-step column chromatography. FerL was expressed as inclusion bodies. The denatured form of FerL was obtained by a simple washing step of the inclusion bodies with 3 M urea. The reconstitution experiment was conducted with various molar ratios of urea-denatured FerH and FerL to make the ferritin nanoparticle with a controlled composition of FerH and FerL. SDS-PAGE analysis of the reconstituted ferritins revealed that the reconstitution required the presence of more than 40 molar$\%$ of FerH in the reconstitution mixture. The assembly of the subunits into the ferritin nanoparticle was confmned by the presence of spherical particles with diameter of 10 nm by the atomic force microscopic image. Further analysis of the particles by using a transmission electron microscope revealed that the reconstituted particles exhibited different percentages of population with dense iron core. The reconstituted ferritin nanoparticles made with molar ratios of [FerH]/[FerL]=l00/0 and 60/40 showed that 80 to $90\%$ of the particles were apoferritin, devoid of iron core. On the contrary, all the particles formed with [FerH]/[FerL]=85/ 15 were found to contain the iron core. This suggests that although FerH can uptake iron, a minor portion of FerL, not exceeding $40\%$ at most, is required to deposit iron inside the particle.

내열성 플라스틱 광섬유 코어재료의 열적 및 광학적 성질 (Thermal and Optical Properties of Heat-Resistant Core Materials in Plastic Optical Fiber)

  • 이규호;조원근;박민;이현정
    • 폴리머
    • /
    • 제30권2호
    • /
    • pp.158-161
    • /
    • 2006
  • 본 연구에서는 고온 고압하의 반응기내에서 일차 아민(primary amine)과 PMMA의 이미드화 반응을 유도하여 내열성 플라스틱 광섬유(plastic optical fiber, POF) 재료인 polyglutarimide(PGI)를 제조하였다. 에틸 아민과 이소프로필 아민, 두 종류를 사용하였으며, 반응시 함량을 다르게 하여 합성한 후 PGI의 여러 가지 물성을 비교하였다. $^1H$ NMR과 FTIR을 사용하여 PGI의 이미드 전환율을 비교하였고, DSC와 TGA를 통해 열적 특성을 조사하였다. 에틸 아민을 사용하여 합성된 PGI 화합물들이 높은 이미드 전환율을 보이면서 향상된 내열성을 나타내었다. POF재료로서 필수적인 광학적 성질은 분광광도계와 아베굴절계로 굴절률과 광 투과율을 조사하였다. 대부분의 PGI는 PMMA 수준의 광 투과율을 유지하였으며, 보다 높은 굴절률을 나타내었다. 이것은 합성된 PGI가 POF 코어물질로써 우수한 광 효율 및 내열성 향상에 기여할 수 있음을 의미한다.

Solutions for the Location-Based Services

  • Kim, K.H.;Hong, S.G.;Park, J.H.;Lee, J.H.
    • 대한원격탐사학회:학술대회논문집
    • /
    • 대한원격탐사학회 2003년도 Proceedings of ACRS 2003 ISRS
    • /
    • pp.651-653
    • /
    • 2003
  • As a result of the project 'Development of core technology for open LBS', we developed several solutions such as personal navigation system, mobile game, and emergency system. In this paper, we explain the approach and architecture of these solutions and consider their meaning on spatial information bases and expectation in the future computing environments. The final goal of this suggested solution is to test the efficiency of our open LBS system and verify the applicability and usability in real application environments. Our approaches will be headed to the future ubiquitous computing environments.

  • PDF

주의력결핍 과잉행동장애 한국형 치료 권고안 개정안(I) - 서론, 임상양상 및 공존질환 - (The Revised Korean Practice Parameter for the Treatment of Attention-Deficit Hyperactivity Disorder (I) - Clinical Presentation and Comorbidity -)

  • 김은진;김윤신;서완석;이소희;박은진;배승민;신동원
    • Journal of the Korean Academy of Child and Adolescent Psychiatry
    • /
    • 제28권2호
    • /
    • pp.46-57
    • /
    • 2017
  • Attention-deficit hyperactivity disorder (ADHD) is a common psychiatric disorder that can affect individuals across their lifespan. It is characterized by the core symptoms of inattention, impulsivity and hyperactivity. ADHD develops as a result of the complex interplay between genetic and environmental factors. Children and adults with ADHD usually suffer concomitantly from other psychiatric comorbidities, including both externalizing and internalizing disorders. It is associated with functional impairment and poor long-term outcomes. This review aims to summarize the key findings from recent research into ADHD and its prevalence, core symptoms, cause and comorbidities from childhood to adulthood.

Influence of Crown Margin Design on the Stress Distribution in Maxillary Canine Restored by All-Ceramic Crown: A Finite Element Analysis

  • Ozer, Zafer;Kurtoglu, Cem;Mamedov, Amirullah M.;Ozbay, Ekmel
    • Journal of Korean Dental Science
    • /
    • 제8권1호
    • /
    • pp.28-35
    • /
    • 2015
  • Purpose: To investigate the influence of crown margin design on the stress distribution and to localize critical sites in maxillary canine under functional loading by using three dimensional finite element analysis. Materials and Methods: The bite force of 100 N, 150 N, and 200 N was applied with an angulation of $45^{\circ}$ to the longitudinal axis of tooth. Six models were restored with IPS e.max (Ivoclar Vivadent, Schaan, Liechtenstein) with a different margin design. With lingual ledge and various thicknesses, three different core ceramics were designed in each model. Result: In the core ceramic, the maximum tensile stresses were found at the labiocervical region. In the veneering ceramic the maximum tensile stresses were found at the area where the force was applied in all models. Conclusion: Shoulder and chamfer margin types are acceptable for all-ceramic rehabilitations. A ledge on the core ceramic at cervical region may affect the strength of all-ceramic crowns.

Insulation Test for the 22.9 kV Class HTS Power Transmission Cable

  • J.W. Cho;Kim, H.J.;K.C. Seong;H.M. Jang;Kim, D.W.;Kim, S.H.
    • 한국초전도ㆍ저온공학회논문지
    • /
    • 제5권3호
    • /
    • pp.48-51
    • /
    • 2003
  • HTS power transmission cable is expected to transport large electric power with a compact size. We are developing a 3-core, 22.9 kV, 50 MVA class HTS power cable, and each core consists of a conductor and shield wound with Bi-2223 tapes, electrical insulation with laminated polypropylene paper (LPP) impregnated with liquid nitrogen. This paper describes the design and experimental results of the model cable for the 22.9 kV, 50 MVA class HTS power transmission cable. The model cable was used the SUS tapes instead of HTS tapes because of testing the electrical characteristics only. The model cable was 1.3 m long and electrical insulation thickness was 4.5 mm. The model cable was evaluated the partial discharge (PD), AC and Impulse withstand voltage in liquid nitrogen. The AC and Impulse withstands voltage and PD inception stress was satisfied with the standard of Korea Electric Power Corporation (KEPCO) in the test results. The 3-core 22.9 kV, 50 MVA class HTS power cable has been designed and manufactured based on these experimental results.